Current Strategies in Development of New Chromone Derivatives with Diversified Pharmacological Activities: A Review

Synthesis, in vitro α-glucosidase inhibitory activity and docking studies of novel chromone-isatin derivatives

(2018) Guangcheng Wang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis and molecular docking study of new benzofuran and furo[3,2- g ]chromone-based cytotoxic agents against breast cancer and p38α MAP kinase inhibitors

(2018) Kamelia M. Amin et al.   BIOORGANIC CHEMISTRY

Synthesis, characterization and antioxidant activity of chitosan-chromone derivatives

(2018) Cahit Demetgül et al.   CARBOHYDRATE POLYMERS

Synthesis, nematicidal activity and docking study of novel chromone derivatives containing substituted pyrazole

(2018) Wei Li et al.   CHINESE CHEMICAL LETTERS

Ionic Liquid-Promoted Synthesis of Novel Chromone-Pyrimidine Coupled Derivatives, Antimicrobial Analysis, Enzyme Assay, Docking Study and Toxicity Study

(2018) Shailee Tiwari et al.   MOLECULES

Identification of potent chromone embedded [1,2,3]-triazoles as novel anti-tubercular agents

(2018) Viswanadh Nalla et al.   Royal Society Open Science

Synthesis, molecular docking, and biological activity of 2-vinyl chromones: Toward selective butyrylcholinesterase inhibitors for potential Alzheimer's disease therapeutics

(2018) Galina F. Makhaeva et al.   BIOORGANIC & MEDICINAL CHEMISTRY

When Will Alzheimer's Disease be Cured? A Pharmaceutical Perspective

(2018) Matthew Townsend   JOURNAL OF ALZHEIMERS DISEASE

Synthesis and biological evaluation of novel isoxazolines linked via piperazine to 2- benzoisothiazoles as potent apoptotic agents

(2017) Sathish Byrappa et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis, Molecular Docking, Molecular Dynamics Studies, and Biological Evaluation of 4H-Chromone-1,2,3,4-tetrahydropyrimidine-5-carboxylate Derivatives as Potential Antileukemic Agents

(2017) Zahra Dolatkhah et al.   Journal of Chemical Information and Modeling

One-pot, three-component synthesis and in vitro antibacterial evaluation of novel 3-amino-N-benzyl-1-aryl-1H-benzo[f]chromene-2-carboxamide derivatives

(2017) Behjat Pouramiri et al.   Journal of the Iranian Chemical Society

A novel chromonyl thiohydantoin with anti-proliferative action on primary hepatocellular carcinoma cells

(2017) Cigdem Ozen et al.   MEDICINAL CHEMISTRY RESEARCH

Synthesis and antiprotozoal activity of furanchalcone–quinoline, furanchalcone–chromone and furanchalcone–imidazole hybrids

(2017) Elisa García et al.   MEDICINAL CHEMISTRY RESEARCH

Synthesis, leishmanicidal, trypanocidal and cytotoxic activities of quinoline-chalcone and quinoline-chromone hybrids

(2017) Juan C. Coa et al.   MEDICINAL CHEMISTRY RESEARCH

Synthesis and cytotoxicity evaluation of some novel chromone annulated phosphorus heterocycles

(2017) Tarik E. Ali et al.   PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS

New Hybrid Hydrazinyl Thiazole Substituted Chromones: As Potential α-Amylase Inhibitors and Radical (DPPH & ABTS) Scavengers

(2017) Uzma Salar et al.   Scientific Reports

Synthesis and anticancer activity of novel 4-morpholino-7,8-dihydro-5H-thiopyrano[4,3-d]pyrimidine derivatives bearing chromone moiety

(2016) Chengyu Sun et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis and Antimicrobial Activity of Furochromone, Benzofuran and Furocoumarin Derivatives Bearing Sulfonyl Moiety

(2016) Sadia A. Hessein et al.   CROATICA CHEMICA ACTA

Flavonoid derivatives as selective ABCC1 modulators: Synthesis and functional characterization

(2016) José Esteban Obreque-Balboa et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Novel chromone and xanthone derivatives: Synthesis and ROS/RNS scavenging activities

(2016) Carina Proença et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of Succinimide-Containing Chromones, Naphthoquinones, and Xanthones under Rh(III) Catalysis: Evaluation of Anticancer Activity

(2016) Sang Hoon Han et al.   JOURNAL OF ORGANIC CHEMISTRY

Synthesis and antimicrobial evaluation of some novel thiomorpholine derived 1,4-disubstituted 1,2,3-triazoles

(2016) Kumaraswamy Battula et al.   JOURNAL OF THE SERBIAN CHEMICAL SOCIETY

Synthesis and evaluation of chromone-2-carboxamide derivatives as cytotoxic agents and 5-lipoxygenase inhibitors

(2016) Fatima Bousejra-ElGarah et al.   MEDICINAL CHEMISTRY RESEARCH

Synthesis, antimicrobial evaluation, and molecular docking studies of novel chromone based 1,2,3-triazoles

(2016) Vidya S. Dofe et al.   RESEARCH ON CHEMICAL INTERMEDIATES

Synthesis and biological screening of some chromonyl-substituted heterocycles derived from 2(3H)-furanone derivative

(2016) Ahmed K. El-Ziaty et al.   SYNTHETIC COMMUNICATIONS

Synthesis of 3-(2-nitrovinyl)-4H-chromones: useful scaffolds for the construction of biologically relevant 3-(pyrazol-5-yl)chromones

(2016) Raquel G. Soengas et al.   TETRAHEDRON

Discovery of the first A1 adenosine receptor ligand based on the chromone scaffold

(2016) F. Cagide et al.   RSC Advances

Design, synthesis and evaluation of chromone-2-carboxamido-alkylbenzylamines as multifunctional agents for the treatment of Alzheimer’s disease

(2015) Qiang Liu et al.   BIOORGANIC & MEDICINAL CHEMISTRY

A new class of hybrid anticancer agents inspired by the synergistic effects of curcumin and genistein: Design, synthesis, and anti-proliferative evaluation

(2015) Qiao-Hong Chen et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Design, synthesis and docking studies of novel thienopyrimidine derivatives bearing chromone moiety as mTOR/PI3Kα inhibitors

(2015) Wufu Zhu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis, carbonic anhydrase inhibition and cytotoxic activity of novel chromone-based sulfonamide derivatives

(2015) Fadi M. Awadallah et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

In Vitro Studies of Chromone-Tetrazoles against Pathogenic Protozoa, Bacteria, and Fungi

(2015) Pedro Cano et al.   MOLECULES

Synthesis and anti-inflammatory activities of 4H-chromene and chromeno[2,3-b]pyridine derivatives

(2015) Shu-Ting Chung et al.   RESEARCH ON CHEMICAL INTERMEDIATES

Antimalarial activity of HIV-1 protease inhibitor in chromone series

(2014) Pradith Lerdsirisuk et al.   BIOORGANIC CHEMISTRY

Synthesis and Biological Evaluation of 3-Styrylchromone Derivatives as Free Radical Scavengers and α-Glucosidase Inhibitors

(2014) Koichi Takao et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

Synthesis of Some New Heterocyclic Compounds Derived from 3-Formylchromones and Their Antimicrobial Evaluation

(2014) A. Bari et al.   Chemistry of Heterocyclic Compounds

Chromones and their Derivatives as Radical Scavengers: A Remedy for Cell Impairment

(2014) Preeti Yadav et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Rational design, synthesis and evaluation of chromone-indole and chromone-pyrazole based conjugates: Identification of a lead for anti-inflammatory drug

(2014) Shaveta et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis, Antiproliferative, and c-Src Kinase Inhibitory Activities of 4-Oxo-4H-1-benzopyran Derivatives

(2014) Karam Chand et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

Synthesis, Leishmanicidal and Cytotoxic Activity of Triclosan-Chalcone, Triclosan-Chromone and Triclosan-Coumarin Hybrids

(2014) Elver Otero et al.   MOLECULES

Design, synthesis and anticancer activity of benzofuran derivatives targeting VEGFR-2 tyrosine kinase

(2014) Omaima M. Abdelhafez et al.   RSC Advances

Design and synthesis of novel chromenone derivatives as interleukin-5 inhibitors

(2013) Eeda Venkateswararao et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Design, Synthesis and Antiviral Activity of 2-(3-Amino-4-piperazinylphenyl)chromone Derivatives

(2013) Mi Kyoung Kim et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

Antioxidant Activities of Some New Chromonyl-2,4-Thiazolidinediones and Chromonyl-2,4-Imidazolidinediones Having Chromone Cores

(2013) Paweł Berczyński et al.   JOURNAL OF FLUORESCENCE

Synthesis, characterization, DNA-binding studies and acetylcholinesterase inhibition activity of new 3-formyl chromone derivatives

(2013) Mehtab Parveen et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

6-Methyl 3-chromonyl 2,4-thiazolidinedione/2,4-imidazolidinedione/2-thioxo-imidazolidine-4-one compounds: novel scavengers of reactive oxygen species

(2013) Paweł Berczyński et al.   LUMINESCENCE

Development of PI3K inhibitors: lessons learned from early clinical trials

(2013) Jordi Rodon et al.   Nature Reviews Clinical Oncology

Synthesis and cytotoxicity evaluation of regioisomeric substituted N-phenyl-3′-(chrom-4-one-3-yl)-isoxazolidines: induction of apoptosis through a mitochondrial-dependent pathway

(2013) Gagandeep Singh et al.   MedChemComm

Novel benzofuran–chromone and –coumarin derivatives: synthesis and biological activity in K562 human leukemia cells

(2013) Clemens Zwergel et al.   MedChemComm

Synthesis and biological evaluation of novel piperazine derivatives of flavone as potent anti-inflammatory and antimicrobial agent

(2012) Girish D. Hatnapure et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis and biological activity assays of some new N1-(flavon-7-yl)amidrazone derivatives and related congeners

(2012) Marwa N. Abu-Aisheh et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and antidiabetic activity of 2,4-thiazolidindione, imidazolidinedione and 2-thioxo-imidazolidine-4-one derivatives bearing 6-methyl chromonyl pharmacophore

(2012) Meltem Ceylan Unlusoy et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

New Tacrine–4-Oxo-4H-chromene Hybrids as Multifunctional Agents for the Treatment of Alzheimer’s Disease, with Cholinergic, Antioxidant, and β-Amyloid-Reducing Properties

(2012) María Isabel Fernández-Bachiller et al.   JOURNAL OF MEDICINAL CHEMISTRY

Ultrasonication-Induced Synthesis and Antimicrobial Evaluation of Some Multifluorinated Pyrazolone Derivatives

(2012) Anil Gadhave et al.   Journal of Chemistry

Synthesis and anticancer activity of chromone-based analogs of lavendustin A

(2010) Dong Hyuk Nam et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and evaluation of indole, pyrazole, chromone and pyrimidine based conjugates for tumor growth inhibitory activities – Development of highly efficacious cytotoxic agents

(2010) Palwinder Singh et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and antidiabetic activity of some new chromonyl-2,4-thiazolidinediones

(2010) Meltem Ceylan-Ünlüsoy et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Chromone derivatives from the wood-decay fungus Rhizina sp. BCC 12292

(2010) Masahiko Isaka et al.   Phytochemistry Letters

Synthesis and antitumor activity of novel dithiocarbamate substituted chromones

(2009) Wei Huang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY