Article
Optics
Jing-Zhi Huang, Wen-Qi Wei, Jia-Jian Chen, Zi-Hao Wang, Ting Wang, Jian-Jun Zhang
Summary: This study achieved the monolithic integration of a stable III-V laser on a standard silicon-on-insulator substrate, proposed a double-side heat dissipation design, successfully demonstrated room-temperature operation of InAs/GaAs QD lasers, and showed the effectiveness of top heat sink design through thermal profile simulation.
Article
Optics
Hao Liang, Tingting Jin, Chaodan Chi, Jialiang Sun, Xiaolei Zhang, Tiangui You, Min Zhou, Jiajie Lin, Shumin Wang
Summary: This research successfully fabricated communication band InAs QD ridge waveguide lasers on GaAsOI substrates using ion-slicing technique and molecular beam epitaxy growth. The devices showed comparable performance to those on GaAs substrates, demonstrating great potential for highly integrated light sources on silicon for photonic integrated circuits.
Article
Chemistry, Multidisciplinary
Junjie Yang, Keshuang Li, Hui Jia, Huiwen Deng, Xuezhe Yu, Pamela Jurczak, Jae-Seong Park, Shujie Pan, Wei Li, Siming Chen, Alwyn Seeds, Mingchu Tang, Huiyun Liu
Summary: This study clarifies the mechanism of APB annihilation and the interaction between TDs and periodic APBs during the growth of GaAs on a CMOS-compatible Si (001) substrate. It is found that both APBs and TDs can be reduced simultaneously by optimizing GaAs growth methods. This finding opens up possibilities for growing high-performance III-V optoelectronic devices on CMOS-compatible Si (001) substrates.
Article
Optics
Zi-Hao Wang, Wen-Qi Wei, Qi Feng, Ting Wang, Jian-Jun Zhang
Summary: Silicon-based InAs quantum dot mode locked lasers offer advantages of high frequency, low power consumption, and low-cost production, but larger linewidths may introduce additional phase noise. A demonstration of a single section MLL grown on a silicon substrate showed significant reduction in RF linewidth through self-injection feedback locking.
Article
Chemistry, Multidisciplinary
Buqing Xu, Guilei Wang, Yong Du, Yuanhao Miao, Ben Li, Xuewei Zhao, Hongxiao Lin, Jiahan Yu, Jiale Su, Yan Dong, Tianchun Ye, Henry H. Radamson
Summary: This manuscript presents the integration of high-performance Si-based III-V quantum-dot lasers on an advanced GaAs virtual substrate. By modifying the GaAs crystal, the lasers achieved low defect density and improved performance. This work provides a feasible proposal for integrating efficient O-band lasers with a standard Si platform in the future.
Article
Materials Science, Multidisciplinary
Lina Zhu, Jun Wang, Yuanqing Yang, Guofeng Wu, Weirong Chen, Yongqing Huang, Xiaomin Ren
Summary: The study introduces a silicon-based multi-wavelength microring laser array, which achieves stable multi-wavelength laser output in the 1.3 μm band through numerically optimized structure parameters. Results show that specific structure parameters lead to stable mode wavelength output and high optical coupling efficiency.
APPLIED PHYSICS A-MATERIALS SCIENCE & PROCESSING
(2021)
Article
Physics, Applied
Shihao Ding, Bozhang Dong, Heming Huang, John Bowers, Frederic Grillot
Summary: The spectral dependence of the linewidth enhancement factor (alpha(H)-factor) of a multimode InAs/GaAs quantum dot laser was analyzed. The results show that the induced conversion efficiency is increased at lasing wavelengths where the linewidth enhancement is lower.
APPLIED PHYSICS LETTERS
(2022)
Review
Optics
Eric Tournie, Laura Monge Bartolome, Marta Rio Calvo, Zeineb Loghmari, Daniel A. Diaz-Thomas, Roland Teissier, Alexei N. Baranov, Laurent Cerutti, Jean-Baptiste Rodriguez
Summary: This article reviews the research field of mid-infrared semiconductor lasers integrated on Si substrates, with a focus on the epitaxial integration of antimonide lasers. It explains the high-performance diode lasers, quantum cascade lasers, and interband cascade lasers achieved through molecular-beam epitaxy and metal-organic vapor phase epitaxy techniques. The article also discusses the potential of etching the facets of antimonide lasers grown on Si for photonic integrated circuits.
LIGHT-SCIENCE & APPLICATIONS
(2022)
Article
Nanoscience & Nanotechnology
Abhiroop Chellu, Eero Koivusalo, Marianna Raappana, Sanna Ranta, Ville Polojarvi, Antti Tukiainen, Kimmo Lahtonen, Jesse Saari, Mika Valden, Heli Seppanen, Harri Lipsanen, Mircea Guina, Teemu Hakkarainen
Summary: Several passivation techniques for close-to-surface InAs/GaAs quantum dots were compared for their ability to preserve optical properties. It was found that AlNx passivation method significantly reduces surface recombination velocity and shows long-term stability.
Article
Physics, Applied
Junjie Yang, Zizhuo Liu, Pamela Jurczak, Mingchu Tang, Keshuang Li, Shujie Pan, Ana Sanchez, Richard Beanland, Jin-Chuan Zhang, Huan Wang, Fengqi Liu, Zhibo Li, Samuel Shutts, Peter Smowton, Siming Chen, Alwyn Seeds, Huiyun Liu
Summary: This paper investigates the replacement of a thin Ge buffer layer for part of the GaAs buffer layer in a III-V quantum-dot laser grown on Si, resulting in improved laser performance. By using this approach, a very high operating temperature of 130 degrees Celsius has been demonstrated for the InAs/GaAs QD laser.
JOURNAL OF PHYSICS D-APPLIED PHYSICS
(2021)
Article
Optics
Andres Remis, Laura Monge-Bartolome, Michele Paparella, Audrey Gilbert, Guilhem Boissier, Marco Grande, Alan Blake, Liam O'Faolain, Laurent Cerutti, Jean-Baptiste Rodriguez, Eric Tournie
Summary: Silicon photonics is a key technology in many fields, enabled by mature Si process technology, large silicon wafer size, and promising Si optical properties. However, monolithic integration of III-V lasers and Si photonic devices on the same Si substrate has been a challenge. In this study, we demonstrate the first semiconductor laser grown on a patterned Si photonics platform with light coupled into a waveguide. This work lays an important foundation for future low-cost, large-scale, fully integrated photonic chips.
LIGHT-SCIENCE & APPLICATIONS
(2023)
Article
Physics, Multidisciplinary
Antian Du, Chunfang Cao, Shixian Han, Hailong Wang, Qian Gong
Summary: This paper reports the realization of high performance 1.31µm InAs/GaAs quantum dot lasers on a Si substrate with all-MBE. Under continuous wave operation mode, Si-based InAs quantum dot lasers with a narrow ridge structure achieved a low threshold current density of 375 A cm(-2), high output power of 63 mW, and high operating temperature of 80°C. It has great potential for application in the development of Si-based photonic integration circuits.
Article
Optics
M. Al Huwayz, H. V. A. Galeti, O. M. Lemine, K. H. Ibnaouf, A. Alkaoud, Y. Alaskar, A. Salhi, S. Alhassan, S. Alotaibi, A. Almalki, A. Almunyif, A. Alhassni, D. A. Jameel, Y. Galvao Gobato, M. Henini
Summary: Extensive research has been done on InAs quantum dots grown on GaAs substrates, but using different substrate materials such as silicon for achieving full integration of photonic and electronic systems remains a challenge. In this study, the effect of substrate material (Si and GaAs) and strain reducing layer on the optical properties of InAs quantum dots was investigated. The results show that InAs quantum dots grown on Si substrate exhibit a red shift in photoluminescence peak energy compared to those grown on GaAs substrate, accompanied by a broadening of the photoluminescence spectrum. This finding opens up new possibilities for controlling the emission of InAs quantum dots and integrating them into photonic devices using Si substrates.
JOURNAL OF LUMINESCENCE
(2022)
Article
Nanoscience & Nanotechnology
Ya-Qi Qiu, Zun-Ren Lv, Hong Wang, Hao-Miao Wang, Xiao-Guang Yang, Tao Yang
Summary: The direct Si doping significantly improves the linewidth enhancement factor of 1.3-mu m InAs/GaAs quantum dot lasers, reducing the alpha(H)-factor. The increase in electron quasi-Fermi level in conduction due to Si doping leads to population inversion and accelerated capture of electrons into QDs with strengthened confinement effect.
Article
Chemistry, Multidisciplinary
Jingwei Mu, Shaoyun Huang, Zhi-Hai Liu, Weijie Li, Ji-Yin Wang, Dong Pan, Guang-Yao Huang, Yuanjie Chen, Jianhua Zhao, H. Q. Xu
Summary: The research team successfully demonstrated a highly tunable linear quadruple QD system in a nanowire and obtained characteristic two-dimensional charge stability diagrams through electron transport measurements, providing important experimental evidence for studying multiple QD systems.
Article
Fisheries
Jing Wu, Yifan Nie, Jingya Wang, Guoqing Feng, Le Hao, Yanping Ma, Yugu Li, Zhenxing Liu
Summary: This study found the phagocytic ability in largemouth bass B cells and investigated the regulatory mechanism of phagocytosis. The results suggested that the Fc gamma receptor-mediated phagocytosis signaling pathway is involved in the phagocytosis of B cells.
JOURNAL OF FISH BIOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Xiaopei Zhou, Qingsong Xi, Weimin Jia, Zhou Li, Zhenxing Liu, Geng Luo, Chenxi Xing, Dazhi Zhang, Meiqi Hou, Huihui Liu, Xue Yang, Yalin Luo, Xuejie Peng, Guihua Wang, Tingting Zou, Lixia Zhu, Lei Jin, Xianqin Zhang
Summary: Male infertility is a global public health problem with complex pathogenic causes. Through whole-exome sequencing, we identified a novel homozygous missense mutation in the ACTL7A gene in two infertile brothers with teratozoospermia. In vitro fertilization and intracytoplasmic sperm injection showed fertilization failure, and further analysis revealed irregular perinuclear theca (PT) and acrosomal ultrastructural defects in the sperm of these patients. The mutation also caused abnormal localization and reduced expression of PLCZ1, which may contribute to the fertilization failure. This study expands the understanding of ACTL7A mutations and provides a basis for genetic counseling.
MOLECULAR GENETICS AND GENOMICS
(2023)
Correction
Oncology
Hong Zhao, Zhen-Dong Liu, Yong-Bo Zhang, Xiao-Yu Gao, Cui Wang, Yi Liu, Xun-Fen Wang
MOLECULAR MEDICINE REPORTS
(2023)
Article
Medicine, General & Internal
Chunmei Jiang, Zhixiang Xu, Jin Li, Jiaqi Zhang, Xingkui Xue, Jingxia Jiang, Guihua Jiang, Xisheng Wang, Yun Peng, Tian Chen, Zhenzhen Liu, Liu Xie, Haibin Gao, Yingxia Liu, Yang Yang
Summary: In this case study, a 31-year-old immunocompetent adult was diagnosed with aseptic meningitis caused by recombinant echovirus 18. The patient recovered after 4 days of antiviral treatment. This is the first report of echovirus 18-induced meningitis in an immunocompetent adult from mainland China, highlighting the importance of surveillance for echovirus 18 infection in both children and adults.
FRONTIERS IN MEDICINE
(2023)
Article
Public, Environmental & Occupational Health
Yunhe Pei, Hailin Chen, Zhenhai Liu, Haozhi Hu
Summary: Environmental pollution is a significant threat to public health, and environmental regulation plays a crucial role in addressing pollution. This study utilizes ologit model and China General Social Survey data to examine the impact and mechanisms of environmental regulation on public health. The findings show that environmental regulation has a positive influence on improving residents' health, which becomes more pronounced over time. The effect varies among residents with different characteristics, with more significant improvements observed among those with higher education levels, urban-registered residences, and residents in economically developed areas. Mechanism analysis reveals that environmental regulation achieves better health outcomes by reducing pollutant emissions and enhancing environmental quality. Additionally, a cost-benefit analysis demonstrates that environmental regulation significantly enhances the welfare of individuals and society as a whole. However, it is crucial to consider the potential negative impact of environmental regulation on residents' employment and income.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Microbiology
Guo-Jie Li, Tie-Zhi Liu, Shou-Mian Li, Shi-Yi Zhao, Cai-Yun Niu, Zhen-Zhen Liu, Xue-Jiao Xie, Xu Zhang, Lu-Yao Shi, Yao-Bin Guo, Ke Wang, Bin Cao, Rui-Lin Zhao, Ming Li, Chun-Ying Deng, Tie-Zheng Wei
Summary: Four new species, R. begonia, R. photinia, R. rhodochroa, and R. rufa, from northern and southwestern China under coniferous and deciduous trees are proposed. The illustrations and descriptions of R. gracillima, R. leucomarginata, R. roseola, and the above four new species are provided based on morphological characters and phylogenetic analyses. The relationships between these new species and related taxa are discussed.
Article
Clinical Neurology
Xiyu Pan, Jun Qiao, Zhen Liu, Benlong Shi, Saihu Mao, Song Li, Xu Sun, Zezhang Zhu, Yong Qiu
Summary: This study compared radiographic parameters, functional and surgical outcomes between lumbar adolescent idiopathic scoliosis (AIS) and lumbar adult idiopathic scoliosis (AdIS). The AdIS group had larger L3 and L4 tilt and translation, higher T10-L2 angle, smaller T5-T12 angle, and higher VAS scores and pain domain of SRS-22 scores compared to the AIS group. The AdIS group also had longer fusion time, larger TL/L curve angle, and less correction of major curve and vertebral body derotation. However, the incidence of adding-on was similar between the two groups.
Article
Biochemistry & Molecular Biology
Ke Ma, Wei Chen, Xiao-Qi Lin, Zhen-Zhen Liu, Tao Wang, Jia-Bao Zhang, Jian-Gang Zhang, Cheng-Kai Zhou, Yu Gao, Chong-Tao Du, Yong-Jun Yang
Summary: Pure cultures of chicken intestinal microbial species are important for understanding gut microbiota function and developing potential probiotics and bioactive metabolites. This study isolated and identified 507 bacterial isolates, including 89 previously uncultured ones, with 63 Lactobacillus strains exhibiting antibacterial activity against S. Pullorum. L. reuteri strain YPG14 showed strong acid tolerance and other probiotic properties, and its consumption significantly improved body weight, reduced S. Pullorum loads, and alleviated damage caused by S. Pullorum.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Chemistry, Physical
M. Y. Ruan, Z. L. Guo, Q. C. Luo, L. Wang, X. L. Wei, T. Y. Li
Summary: We investigated the size effect on the magnetocaloric effect (MCE) of Er2BaNiO5, a Haldane spin-chain antiferromagnet. The results showed that the decrease in average crystallite size led to an enhancement of magnetization and paramagnetic-like behavior. The dominant antiferromagnetic (AFM) interactions in the bulk sample were suppressed in the nano-size samples, resulting in a dramatic reduction of the Haldane gap. Additionally, the size effect significantly influenced the MCE, leading to a monotonic increase in MCE in the nano-size samples compared to the disappearance of negative MCE in the bulk sample. The maximum entropy change of the nano-size samples increased nearly 3.2 times compared to the bulk sample. The ESR results confirmed the increasing of paramagnetic (PM) ions in the nano-size samples, as evidenced by the observed ESR signals of Er3+ and Ni2+ ions.
JOURNAL OF ALLOYS AND COMPOUNDS
(2023)
Article
Environmental Sciences
Jian-qiang Zhang, Zong-ji Yang, Qing-kai Meng, Jiao Wang, Kai-heng Hu, Yong-gang Ge, Feng-huan Su, Bo Zhao, Bo Zhang, Ning Jiang, Yu Huang, Zai-yang Ming, Yi-fan Zhang, Zhen-xing Liu, Chun-hao Wu, Wen-tao Zhou, Xin-yue Liang, Yu-qing Sun, Lian-bing Yang, Hong-kun Yao, Pei-hua Feng, Jia-li Liu
Summary: At 12:52 pm on September 5, 2022, a Ms 6.8 earthquake occurred in Luding County, Sichuan Province, China. A total of 8685 earthquake-triggered landslides (EQTLs) covering an area of 30.7 km(2) were identified based on aerial photographs, satellite imageries, and field investigation. The characteristics of these EQTLs were analyzed, including their distribution along fault lines, rivers, and roads, as well as their association with ground deformation caused by the earthquake.
JOURNAL OF MOUNTAIN SCIENCE
(2023)
Article
Microbiology
Ting-Ting Du, Xiao-Chen Liu, Yu He, Xiong Gao, Zhen-Zhen Liu, Zheng-Li Wang, Lu-Quan Li
Summary: This study aimed to explore the value of gut microbiota and tricarboxylic acid (TCA) metabolites in early diagnosis of NEC among infants with abdominal manifestations. High-throughput sequencing was used to analyze the gut microbiota, and multiple reaction monitoring (MRM) targeted metabolomics was used to measure TCA metabolites. The results showed that decreased levels of unclassified Staphylococcus, Lactobacillaceae, and Bifidobacterium animalis subsp. lactis at the species level, as well as increased levels of succinate, L-malic acid, and oxaloacetate, have potential value for the early diagnosis of NEC.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Pharmacology & Pharmacy
Hua Miao, Yan-Ni Wang, Xiao-Yong Yu, Liang Zou, Yan Guo, Wei Su, Fei Liu, Gang Cao, Ying-Yong Zhao
Summary: This study identified alterations in gut microbiota and serum metabolites mediating an AhR mechanism in MN rats and IMN patients, providing insights into the pathogenesis of MN.
BRITISH JOURNAL OF PHARMACOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Pengfei Li, Shuxin Xu, Yanjie Han, Hui He, Zhen Liu
Summary: A machine learning-empowered mass spectrometry platform was developed for accurate profiling and quantification of cis-diol metabolites associated with liver cancer. The platform improved the detection coverage and demonstrated higher sensitivity and specificity in diagnosing liver cancer compared to protein biomarker-based methods.
Article
Chemistry, Multidisciplinary
Weihua Lu, Jingran Chen, Zhanchen Guo, Yanyan Ma, Zikuan Gu, Zhen Liu
Summary: Hypervalent bispecific gold nanoparticle-anchored aptamer chimeras (AuNP-APTACs) were developed as effective lysosome-targeting chimeras (LYTACs) for reversing multidrug resistance (MDR) in cancer cells by degrading the ABCG2 protein. The AuNP-APTACs improved drug accumulation in resistant cells and showed comparable efficacy to small-molecule inhibitors. This new strategy holds great promise for overcoming MDR and has significant implications for cancer therapy.
CHEMICAL COMMUNICATIONS
(2023)
Proceedings Paper
Computer Science, Artificial Intelligence
Ben Fei, Zhaoyang Lyu, Liang Pan, Junzhe Zhang, Weidong Yang, Tianyue Luo, Bo Zhang, Bo Dai
Summary: This work proposes the Generative Diffusion Prior (GDP) method to effectively model the posterior distributions in image restoration. GDP can handle both linear and non-linear problems, and achieve blind image restoration by optimizing the degradation model parameters. Experimental results demonstrate the versatility of GDP on various image datasets.
2023 IEEE/CVF CONFERENCE ON COMPUTER VISION AND PATTERN RECOGNITION (CVPR)
(2023)
