Journal
CLINICAL NUCLEAR MEDICINE
Volume 41, Issue 10, Pages e449-e451Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/RLU.0000000000001291
Keywords
PSMA; PET/CT; cerebral metastasis; ischemic stroke; MRI; pitfall; GCPII
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A 65-year-old man with disseminated bone metastases of prostate cancer was referred for Ga-68-PSMA-HBED-CC-PET/CT (short PSMA-PET/CT) to exclude visceral metastases before treatment of bone metastases with Ra-223-dichloride. Apart from disseminated bone metastases, PSMA-PET/CT revealed a focal cerebral tracer uptake in the right frontal lobe highly suspicious for cerebral spread. According to patient history, a cerebral infarction occurred 14 days before PSMA imaging in corresponding localization confirmed by MRI scanning. This case demonstrates the possibility of false-positive finding of cerebral metastases in PSMA-PET early after stroke.
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