Interleukin-6 trans-signaling increases the expression of carcinoembryonic antigen-related cell adhesion molecules 5 and 6 in colorectal cancer cells

Colorectal carcinogenesis-update and perspectives

(2015) Hans Raskov   WORLD JOURNAL OF GASTROENTEROLOGY

European cancer mortality predictions for the year 2014

(2014) M. Malvezzi et al.   ANNALS OF ONCOLOGY

Diagnostic value of preoperative serum carcinoembryonic antigen and carbohydrate antigen 19-9 in colorectal cancer

(2014) E. Polat et al.   Current Oncology

Diet-induced hypoxia responsive element demethylation increases CEACAM6 expression, favouring Crohn's disease-associatedEscherichia colicolonisation

(2014) Jérémy Denizot et al.   GUT

Master regulator of intestinal disease: IL-6 in chronic inflammation and cancer development

(2014) Maximilian J. Waldner et al.   SEMINARS IN IMMUNOLOGY

Ulcerative colitis-associated colorectal cancer

(2014) Masakazu Yashiro   WORLD JOURNAL OF GASTROENTEROLOGY

Carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) in cancer progression and metastasis

(2013) Nicole Beauchemin et al.   CANCER AND METASTASIS REVIEWS

Declining Risk of Colorectal Cancer in Inflammatory Bowel Disease

(2013) Maurice W. M. D. Lutgens et al.   INFLAMMATORY BOWEL DISEASES

STAT3 and HIF1α cooperatively activate HIF1 target genes in MDA-MB-231 and RCC4 cells

(2013) M R Pawlus et al.   ONCOGENE

Interleukin-6: From basic biology to selective blockade of pro-inflammatory activities

(2013) Jürgen Scheller et al.   SEMINARS IN IMMUNOLOGY

Interleukin-6 Trans-Signaling and Colonic Cancer Associated with Inflammatory Bowel Disease

(2012) Athena Chalaris et al.   DIGESTIVE DISEASES

Hitting a complex target: an update on interleukin-6 trans-signalling

(2012) Georg H Waetzig et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Interleukin-6: from an inflammatory marker to a target for inflammatory diseases

(2012) Mercedes Rincon   TRENDS IN IMMUNOLOGY

Hypoxia-inducible Factor-1α Enhances Haptoglobin Gene Expression by Improving Binding of STAT3 to the Promoter

(2011) Mi-Kyung Oh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Species Specificity of ADAM10 and ADAM17 Proteins in Interleukin-6 (IL-6) Trans-signaling and Novel Role of ADAM10 in Inducible IL-6 Receptor Shedding

(2011) Christoph Garbers et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Novel Anti-CEACAM5 Monoclonal Antibody, CC4, Suppresses Colorectal Tumor Growth and Enhances NK Cells-Mediated Tumor Immunity

(2011) Chaogu Zheng et al.   PLoS One

Novel STAT3 Phosphorylation Inhibitors Exhibit Potent Growth-Suppressive Activity in Pancreatic and Breast Cancer Cells

(2010) L. Lin et al.   CANCER RESEARCH

IL-6 and Stat3 Are Required for Survival of Intestinal Epithelial Cells and Development of Colitis-Associated Cancer

(2009) Sergei Grivennikov et al.   CANCER CELL

STAT3 inhibits the degradation of HIF-1α by pVHL-mediated ubiquitination

(2009) Joo Eun Jung et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Defect in CEACAM family member expression in Crohnʼs disease IECs is regulated by the transcription factor SOX9

(2009) Giulia Roda et al.   INFLAMMATORY BOWEL DISEASES

Essential Roles of IL-6 Trans-Signaling in Colonic Epithelial Cells, Induced by the IL-6/Soluble-IL-6 Receptor Derived from Lamina Propria Macrophages, on the Development of Colitis-Associated Premalignant Cancer in a Murine Model

(2009) S. Matsumoto et al.   JOURNAL OF IMMUNOLOGY