Epigenetic priming by Dppa2 and 4 in pluripotency facilitates multi-lineage commitment

Dppa2 and Dppa4 directly regulate the Dux-driven zygotic transcriptional program

(2019) Mélanie Eckersley-Maslin et al.   GENES & DEVELOPMENT

Theoretical analysis of Polycomb-Trithorax systems predicts that poised chromatin is bistable and not bivalent

(2019) Kim Sneppen et al.   Nature Communications

DPPA2/4 and SUMO E3 ligase PIAS4 opposingly regulate zygotic transcriptional program

(2019) Yao-Long Yan et al.   PLOS BIOLOGY

Genomic functions of developmental pluripotency associated factor 4 (Dppa4) in pluripotent stem cells and cancer

(2018) Rachel Herndon Klein et al.   Stem Cell Research

A quantitative mass spectrometry-based approach to monitor the dynamics of endogenous chromatin-associated protein complexes

(2018) Evangelia K. Papachristou et al.   Nature Communications

Histone variants H2A.Z and H3.3 coordinately regulate PRC2-dependent H3K27me3 deposition and gene expression regulation in mES cells

(2018) Yan Wang et al.   BMC BIOLOGY

Dppa2/4 Facilitate Epigenetic Remodeling during Reprogramming to Pluripotency

(2018) Charles Hernandez et al.   Cell Stem Cell

Promoter bivalency favors an open chromatin architecture in embryonic stem cells

(2018) Glòria Mas et al.   NATURE GENETICS

hnRNPK Recruits PCGF3/5-PRC1 to the Xist RNA B-Repeat to Establish Polycomb-Mediated Chromosomal Silencing

(2017) Greta Pintacuda et al.   MOLECULAR CELL

Chromatin-state discovery and genome annotation with ChromHMM

(2017) Jason Ernst et al.   Nature Protocols

2016 update of the PRIDE database and its related tools

(2016) Juan Antonio Vizcaíno et al.   NUCLEIC ACIDS RESEARCH

MERVL/Zscan4 Network Activation Results in Transient Genome-wide DNA Demethylation of mESCs

(2016) Mélanie A. Eckersley-Maslin et al.   Cell Reports

H2A.Z.1 Monoubiquitylation Antagonizes BRD2 to Maintain Poised Chromatin in ESCs

(2016) Lauren E. Surface et al.   Cell Reports

Competition between DNA methylation and transcription factors determines binding of NRF1

(2015) Silvia Domcke et al.   NATURE

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

Tip60 complex binds to active Pol II promoters and a subset of enhancers and co-regulates the c-Myc network in mouse embryonic stem cells

(2015) Sarina Ravens et al.   Epigenetics & Chromatin

Proteins that bind regulatory regions identified by histone modification chromatin immunoprecipitations and mass spectrometry

(2015) Erik Engelen et al.   Nature Communications

Phenotype Specific Analyses Reveal Distinct Regulatory Mechanism for Chronically Activated p53

(2015) Kristina Kirschner et al.   PLoS Genetics

H3K4me3 Breadth Is Linked to Cell Identity and Transcriptional Consistency

(2014) Bérénice A. Benayoun et al.   CELL

Mll2 is required for H3K4 trimethylation on bivalent promoters in embryonic stem cells, whereas Mll1 is redundant

(2014) S. Denissov et al.   DEVELOPMENT

FGF Signaling Inhibition in ESCs Drives Rapid Genome-wide Demethylation to the Epigenetic Ground State of Pluripotency

(2013) Gabriella Ficz et al.   Cell Stem Cell

A double take on bivalent promoters

(2013) P. Voigt et al.   GENES & DEVELOPMENT

The Mll2 branch of the COMPASS family regulates bivalent promoters in mouse embryonic stem cells

(2013) Deqing Hu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

PRC2 binds active promoters and contacts nascent RNAs in embryonic stem cells

(2013) Syuzo Kaneko et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Polycomb Associates Genome-wide with a Specific RNA Polymerase II Variant, and Regulates Metabolic Genes in ESCs

(2012) Emily Brookes et al.   Cell Stem Cell

H2A.Z Facilitates Access of Active and Repressive Complexes to Chromatin in Embryonic Stem Cell Self-Renewal and Differentiation

(2012) Gangqing Hu et al.   Cell Stem Cell

H2A.Z landscapes and dual modifications in pluripotent and multipotent stem cells underlie complex genome regulatory functions

(2012) Manching Ku et al.   GENOME BIOLOGY

Bismark: a flexible aligner and methylation caller for Bisulfite-Seq applications

(2011) Felix Krueger et al.   BIOINFORMATICS

Essential Roles of ECAT15-2/Dppa2 in Functional Lung Development

(2011) T. Nakamura et al.   MOLECULAR AND CELLULAR BIOLOGY

DPPA4 modulates chromatin structure via association with DNA and core histone H3 in mouse embryonic stem cells

(2010) Hisaharu Masaki et al.   GENES TO CELLS

The Pluripotency-Associated Gene Dppa4 Is Dispensable for Embryonic Stem Cell Identity and Germ Cell Development but Essential for Embryogenesis

(2009) B. Madan et al.   MOLECULAR AND CELLULAR BIOLOGY

H2AZ Is Enriched at Polycomb Complex Target Genes in ES Cells and Is Necessary for Lineage Commitment

(2008) Menno P. Creyghton et al.   CELL