Serum amyloid A is a soluble pattern recognition receptor that drives type 2 immunity

Soluble pattern recognition molecules: Guardians and regulators of homeostasis at airway mucosal surfaces

(2020) Ursula Smole et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The Cytokines of Asthma

(2019) Bart N. Lambrecht et al.   IMMUNITY

Serum Amyloid A1 Is an Epithelial Prorestitutive Factor

(2018) Benjamin H. Hinrichs et al.   AMERICAN JOURNAL OF PATHOLOGY

Environmental allergens induce allergic inflammation through proteolytic maturation of IL-33

(2018) Corinne Cayrol et al.   NATURE IMMUNOLOGY

SmSP2: A serine protease secreted by the blood fluke pathogen Schistosoma mansoni with anti-hemostatic properties

(2018) Adrian Leontovyč et al.   PLoS Neglected Tropical Diseases

Prevention of allergy by virus-like nanoparticles (VNP) delivering shielded versions of major allergens in a humanized murine allergy model

(2018) Bernhard Kratzer et al.   ALLERGY

Serum amyloid A promotes LPS clearance and suppresses LPS‐induced inflammation and tissue injury

(2018) Ni Cheng et al.   EMBO REPORTS

Interleukin-33 is activated by allergen- and necrosis-associated proteolytic activities to regulate its alarmin activity during epithelial damage

(2018) Ian C. Scott et al.   Scientific Reports

Serum Amyloid A3 is required for normal lung development and survival following influenza infection

(2018) Jennifer L. Ather et al.   Scientific Reports

Suppression of Lipopolysaccharide-Induced Inflammatory Response by Fragments from Serum Amyloid A

(2017) Huibin Zhou et al.   JOURNAL OF IMMUNOLOGY

Serum amyloid A self-assembles with phospholipids to form stable protein-rich nanoparticles with a distinct structure: A hypothetical function of SAA as a “molecular mop” in immune response

(2017) Nicholas M. Frame et al.   JOURNAL OF STRUCTURAL BIOLOGY

Serum amyloid A forms stable oligomers that disrupt vesicles at lysosomal pH and contribute to the pathogenesis of reactive amyloidosis

(2017) Shobini Jayaraman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Serum amyloid A1: Structure, function and gene polymorphism

(2016) Lei Sun et al.   GENE

An IL-23R/IL-22 Circuit Regulates Epithelial Serum Amyloid A to Promote Local Effector Th17 Responses

(2015) Teruyuki Sano et al.   CELL

The unusual lipid binding proteins of parasitic helminths and their potential roles in parasitism and as therapeutic targets

(2015) Gisela R. Franchini et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Farm dust and endotoxin protect against allergy through A20 induction in lung epithelial cells

(2015) M. J. Schuijs et al.   SCIENCE

Dimerization of lipocalin allergens

(2015) Merja H. Niemi et al.   Scientific Reports

Level of Fatty Acid Binding Protein 5 (FABP5) Is Increased in Sputum of Allergic Asthmatics and Links to Airway Remodeling and Inflammation

(2015) Hille Suojalehto et al.   PLoS One

Association between Group 2 Innate Lymphoid Cells enrichment, nasal polyps and allergy in Chronic Rhinosinusitis

(2014) D. Miljkovic et al.   ALLERGY

IL-21 receptor signalling partially mediates Th2-mediated allergic airway responses

(2014) S. Lajoie et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Group 2 Innate Lymphoid Cells Are Critical for the Initiation of Adaptive T Helper 2 Cell-Mediated Allergic Lung Inflammation

(2014) Timotheus Y.F. Halim et al.   IMMUNITY

Serum amyloid A1 isoforms display different efficacy at Toll-like receptor 2 and formyl peptide receptor 2

(2014) Mingjie Chen et al.   IMMUNOBIOLOGY

Alternaria-derived serine protease activity drives IL-33–mediated asthma exacerbations

(2014) Robert J. Snelgrove et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Group 2 innate lymphoid cells facilitate sensitization to local, but not systemic, TH2-inducing allergen exposures

(2014) Matthew J. Gold et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Structural mechanism of serum amyloid A-mediated inflammatory amyloidosis

(2014) J. Lu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Serum amyloid A is a retinol binding protein that transports retinol during bacterial infection

(2014) Mehabaw G Derebe et al.   eLife

IL-33–Responsive Innate Lymphoid Cells Are an Important Source of IL-13 in Chronic Rhinosinusitis with Nasal Polyps

(2013) Joanne L. Shaw et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Ligand-specific conformational change of the G-protein-coupled receptor ALX/FPR2 determines proresolving functional responses

(2013) S. N. Cooray et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Damage-associated molecular patterns stimulate interleukin-33 expression in nasal polyp epithelial cells

(2013) Gina Paris et al.   International Forum of Allergy & Rhinology

Endogenous Acute Phase Serum Amyloid A Lacks Pro-Inflammatory Activity, Contrasting the Two Recombinant Variants That Activate Human Neutrophils through Different Receptors

(2013) Karin Christenson et al.   Frontiers in Immunology

SAA does not induce cytokine production in physiological conditions

(2012) Myung-Hee Kim et al.   CYTOKINE

IL-33, but not thymic stromal lymphopoietin or IL-25, is central to mite and peanut allergic sensitization

(2012) Derek K. Chu et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Serum amyloid A 2.2 refolds into a octameric oligomer that slowly converts to a more stable hexamer

(2011) Yun Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

IL-33-activated dendritic cells are critical for allergic airway inflammation

(2011) Anne-Gaëlle Besnard et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Allergen-induced expression of IL-25 and IL-25 receptor in atopic asthmatic airways and late-phase cutaneous responses

(2011) Chris J. Corrigan et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Asthma endotypes: A new approach to classification of disease entities within the asthma syndrome

(2011) Jan Lötvall et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

N-Formyl Peptide Receptor 3 (FPR3) Departs from the Homologous FPR2/ALX Receptor with Regard to the Major Processes Governing Chemoattractant Receptor Regulation, Expression at the Cell Surface, and Phosphorylation

(2011) Marie-Josèphe Rabiet et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Serum Amyloid A Activates the NLRP3 Inflammasome and Promotes Th17 Allergic Asthma in Mice

(2011) J. L. Ather et al.   JOURNAL OF IMMUNOLOGY

The proinflammatory activity of recombinant serum amyloid A is not shared by the endogenous protein in the circulation

(2010) Lena Björkman et al.   ARTHRITIS AND RHEUMATISM

Impact of serum amyloid A on high density lipoprotein composition and levels

(2010) Maria C. de Beer et al.   JOURNAL OF LIPID RESEARCH

Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria

(2009) Ivaylo I. Ivanov et al.   CELL

IL-33–activated dendritic cells induce an atypical TH2-type response

(2009) Matthew A. Rank et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

New insights into innate immune mechanisms underlying allergenicity

(2009) M Wills-Karp et al.   Mucosal Immunology

Serum amyloid A: An acute-phase protein involved in tumour pathogenesis

(2008) E. Malle et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Increased T-cell survival by structural bronchial cells derived from asthmatic subjects cultured in an engineered human mucosa

(2008) Marie-Eve Darveau et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY