Role of Rutin in 5-Fluorouracil-Induced Intestinal Mucositis: Prevention of Histological Damage and Reduction of Inflammation and Oxidative Stress

Luteolin prevents irinotecan‐induced intestinal mucositis in mice through antioxidant and anti‐inflammatory properties

(2020) Thaise Boeing et al.   BRITISH JOURNAL OF PHARMACOLOGY

Potential Therapeutic Anti-Inflammatory and Immunomodulatory Effects of Dihydroflavones, Flavones, and Flavonols

(2020) Cristina Zaragozá et al.   MOLECULES

Probiotic mixture containing Lactobacillus spp. and Bifidobacterium spp. attenuates 5-fluorouracil-induced intestinal mucositis in mice

(2019) Marielle Quaresma et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Combined effect of a natural flavonoid rutin from Citrus sinensis and conventional antibiotic gentamicin on Pseudomonas aeruginosa biofilm formation

(2018) Murugesan Sathiya Deepika et al.   FOOD CONTROL

Are phytosomes a superior nanodelivery system for the antioxidant rutin?

(2018) Hanh T.H. Vu et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Troxerutin, a mixture of O -hydroxyethyl derivatives of the natural flavonoid rutin: Chemical stability and analytical aspects

(2018) Michele Bianchi et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Rutin attenuates neurobehavioral deficits, oxidative stress, neuro-inflammation and apoptosis in fluoride treated rats

(2018) Kpobari W. Nkpaa et al.   NEUROSCIENCE LETTERS

Intestinal Anti-Inflammatory Activity of the Aqueous Extract from Ipomoea asarifolia in DNBS-Induced Colitis in Rats

(2018) Valéria da Silva et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Natural Product Interventions for Chemotherapy and Radiotherapy-Induced Side Effects

(2018) Qing-Yu Zhang et al.   Frontiers in Pharmacology

TLR9 Regulates the NF-κB–NLRP3–IL-1β Pathway Negatively inSalmonella-Induced NKG2D-Mediated Intestinal Inflammation

(2017) Yan Li et al.   JOURNAL OF IMMUNOLOGY

Secretion of biologically active pancreatitis-associated protein I (PAP) by genetically modified dairy Lactococcus lactis NZ9000 in the prevention of intestinal mucositis

(2017) Rodrigo D. Carvalho et al.   Microbial Cell Factories

Effect of rutin on proinflammatory cytokines and oxidative stress in toxin-mediated hepatotoxicity

(2017) Noura AlDrak et al.   Toxin Reviews

Positive and Negative Signals in Mast Cell Activation

(2017) Silvia Bulfone-Paus et al.   TRENDS IN IMMUNOLOGY

Rutin attenuates intestinal toxicity induced by Methotrexate linked with anti-oxidative and anti-inflammatory effects

(2016) Raju Gautam et al.   BMC Complementary and Alternative Medicine

MicroRNA-149 Increases the Sensitivity of Colorectal Cancer Cells to 5-Fluorouracil by Targeting Forkhead Box Transcription Factor FOXM1

(2016) Xiaobei Liu et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Prospective, Multicenter Study of 5-Fluorouracil Therapeutic Drug Monitoring in Metastatic Colorectal Cancer Treated in Routine Clinical Practice

(2016) Martin Wilhelm et al.   Clinical Colorectal Cancer

Population Pharmacokinetic–Pharmacodynamic Modeling of 5-Fluorouracil for Toxicities in Rats

(2016) Shinji Kobuchi et al.   EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS

Fractional laser-assisted topical delivery leads to enhanced, accelerated and deeper cutaneous 5-fluorouracil uptake

(2016) Emily Wenande et al.   Expert Opinion on Drug Delivery

Development and evaluation of nanostructured lipid carrier-based hydrogel for topical delivery of 5-fluorouracil

(2016) Paruvathanahalli Rajinikanth et al.   International Journal of Nanomedicine

Flavonoids in Inflammatory Bowel Disease: A Review

(2016) Teresa Vezza et al.   Nutrients

Rutin ameliorates methotrexate induced hepatic injury in rats

(2015) Esra Erdogan et al.   Acta Cirurgica Brasileira

In a Methotrexate-Induced Model of Intestinal Mucositis, Olmesartan Reduced Inflammation and Induced Enteropathy Characterized by Severe Diarrhea, Weight Loss, and Reduced Sucrose Activity

(2015) Aurigena Antunes de Araújo et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Rebamipide Attenuates 5-Fluorouracil-Induced Small Intestinal Mucositis in a Mouse Model

(2015) Hyun Jin Kim et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Elemental diet moderates 5-fluorouracil-induced gastrointestinal mucositis through mucus barrier alteration

(2015) Rei Kawashima et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Rutin nanostructured lipid cosmeceutical preparation with sun protective potential

(2015) Rabab Kamel et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Influence of an elemental diet on 5-fluorouracil-induced morphological changes in the mouse salivary gland and colon

(2015) Rei Kawashima et al.   SUPPORTIVE CARE IN CANCER

Prevalence of oral mucositis, dry mouth, and dysphagia in advanced cancer patients

(2015) Sebastiano Mercadante et al.   SUPPORTIVE CARE IN CANCER

Amelioration of Chemotherapy-Induced Intestinal Mucositis by Orally Administered Probiotics in a Mouse Model

(2015) Chun-Yan Yeung et al.   PLoS One

Treatment with Saccharomyces boulardii reduces the inflammation and dysfunction of the gastrointestinal tract in 5-fluorouracil-induced intestinal mucositis in mice

(2014) Priscilla F. C. Justino et al.   BRITISH JOURNAL OF NUTRITION

The Multifaceted Mast Cell in Inflammatory Bowel Disease

(2014) Matthew J. Hamilton et al.   INFLAMMATORY BOWEL DISEASES

Traditional uses of medicinal plants in gastrointestinal disorders in Nepal

(2014) Maan B. Rokaya et al.   JOURNAL OF ETHNOPHARMACOLOGY

Rutin has intestinal antiinflammatory effects in the CD4+ CD62L+ T cell transfer model of colitis

(2014) Cristina Mascaraque et al.   PHARMACOLOGICAL RESEARCH

Synthesis and antioxidant activities of flavonoids derivatives, troxerutin and 3’, 4’, 7-triacetoxyethoxyquercetin

(2013) Jian-Dong Xu et al.   CHINESE CHEMICAL LETTERS

Low doses of Celecoxib attenuate gut barrier failure during experimental peritonitis

(2013) Scott S Short et al.   LABORATORY INVESTIGATION

The Antioxidant Effects of the Flavonoids Rutin and Quercetin Inhibit Oxaliplatin-Induced Chronic Painful Peripheral Neuropathy

(2013) Maria Isabel Azevedo et al.   Molecular Pain

Development and validation of a HPLC method for the quantification of three flavonoids in a crude extract of Dimorphandra gardneriana

(2013) Leonardo P. Landim et al.   Revista Brasileira de Farmacognosia-Brazilian Journal of Pharmacognosy

CCl4-induced hepatotoxicity: protective effect of rutin on p53, CYP2E1 and the antioxidative status in rat

(2012) Rahmat A Khan et al.   BMC Complementary and Alternative Medicine

Inflammatory intestinal damage induced by 5-fluorouracil requires IL-4

(2012) Pedro M.G. Soares et al.   CYTOKINE

A New and Fast HPLC Method for Determination of Rutin, Troxerutin, Diosmin and Hesperidin in Food Supplements Using Fused-Core Column Technology

(2012) Dalibor Šatínský et al.   Food Analytical Methods

Interaction of wild type, G68R and L125M isoforms of the arylamine-N-acetyltransferase from Mycobacterium tuberculosis with isoniazid: a computational study on a new possible mechanism of resistance

(2012) Ricardo Martins Ramos et al.   JOURNAL OF MOLECULAR MODELING

Leishmanicidal and cholinesterase inhibiting activities of phenolic compounds of Dimorphandra gardneriana and Platymiscium floribundum, native plants from Caatinga biome

(2012) Nadja S. Vila-Nova et al.   PESQUISA VETERINARIA BRASILEIRA

5-Fluorouracil Induced Intestinal Mucositis via Nuclear Factor-κB Activation by Transcriptomic Analysis and In Vivo Bioluminescence Imaging

(2012) Chung-Ta Chang et al.   PLoS One

Management of oral and gastrointestinal mucositis: ESMO Clinical Practice Guidelines

(2011) D. E. Peterson et al.   ANNALS OF ONCOLOGY

Intestinal mast cells in gut inflammation and motility disturbances

(2011) Benedicte Y. De Winter et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Gastroprotective Effect of Rutin against Indomethacin-Induced Ulcers in Rats

(2010) Ihab T. Abdel-Raheem   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Mast cells and inflammation

(2010) Theoharis C. Theoharides et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Influence of rutin treatment on biochemical alterations in experimental diabetes

(2009) Ana Angélica Henrique Fernandes et al.   BIOMEDICINE & PHARMACOTHERAPY

Evaluation for Protective Effect of Rutin, a Natural Flavonoid, against HCl/Ethanol-Induced Gastric Lesions

(2009) Choon-Sik Jeong   Biomolecules & Therapeutics

Regioselective enzymatic acylation of troxerutin in nonaqueous medium

(2009) Yong Mei Xiao et al.   CHINESE CHEMICAL LETTERS

Gastrointestinal Microflora and Mucins May Play a Critical Role in the Development of 5-Fluorouracil-Induced Gastrointestinal Mucositis

(2009) Andrea M. Stringer et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Flavonoids with Gastroprotective Activity

(2009) Kelly Samara de Lira Mota et al.   MOLECULES

In vitro antioxidant properties of rutin

(2007) Jianxiong Yang et al.   LWT-FOOD SCIENCE AND TECHNOLOGY