PSCs Reveal PUFA-Provoked Mitochondrial Stress as a Central Node Potentiating RPE Degeneration in Bietti’s Crystalline Dystrophy

Title
PSCs Reveal PUFA-Provoked Mitochondrial Stress as a Central Node Potentiating RPE Degeneration in Bietti’s Crystalline Dystrophy
Authors
Keywords
BCD-iPSC disease model, CYP4V2 g, ene mutant PSC control, RPE, poly-unsaturated fatty acid, lipotoxicity, AAV2 gene therapy
Journal
MOLECULAR THERAPY
Volume -, Issue -, Pages -
Publisher
Elsevier BV
Online
2020-07-25
DOI
10.1016/j.ymthe.2020.07.024

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