Dissociation of functional and structural plasticity of dendritic spines during NMDAR and mGluR-dependent long-term synaptic depression in wild-type and fragile X model mice

Unconventional NMDA Receptor Signaling

(2017) Kim Dore et al.   JOURNAL OF NEUROSCIENCE

β-Arrestin2 Couples Metabotropic Glutamate Receptor 5 to Neuronal Protein Synthesis and Is a Potential Target to Treat Fragile X

(2017) Laura J. Stoppel et al.   Cell Reports

Mechanistic target of rapamycin is necessary for changes in dendritic spine morphology associated with long-term potentiation

(2017) Fredrick E. Henry et al.   Molecular Brain

Dysregulated NMDA-Receptor Signaling Inhibits Long-Term Depression in a Mouse Model of Fragile X Syndrome

(2016) A. K. H. Toft et al.   JOURNAL OF NEUROSCIENCE

Convergence of Hippocampal Pathophysiology in Syngap+/- and Fmr1-/y Mice

(2015) S. A. Barnes et al.   JOURNAL OF NEUROSCIENCE

Non-Ionotropic NMDA Receptor Signaling Drives Activity-Induced Dendritic Spine Shrinkage

(2015) I. S. Stein et al.   JOURNAL OF NEUROSCIENCE

Contribution of mGluR5 to pathophysiology in a mouse model of human chromosome 16p11.2 microdeletion

(2015) Di Tian et al.   NATURE NEUROSCIENCE

Agonist binding to the NMDA receptor drives movement of its cytoplasmic domain without ion flow

(2015) Kim Dore et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Conformational signaling required for synaptic plasticity by the NMDA receptor complex

(2015) Jonathan Aow et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ionotropic NMDA Receptor Signaling Is Required for the Induction of Long-Term Depression in the Mouse Hippocampal CA1 Region

(2014) W. E. Babiec et al.   JOURNAL OF NEUROSCIENCE

Structural and Molecular Remodeling of Dendritic Spine Substructures during Long-Term Potentiation

(2014) Miquel Bosch et al.   NEURON

GABA promotes the competitive selection of dendritic spines by controlling local Ca2+ signaling

(2013) Tatsuya Hayama et al.   NATURE NEUROSCIENCE

Long Lasting Protein Synthesis- and Activity-Dependent Spine Shrinkage and Elimination after Synaptic Depression

(2013) Yazmín Ramiro-Cortés et al.   PLoS One

Long-term depression and other synaptic plasticity in the cerebellum

(2013) Tomoo HIRANO   PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES

Long-term depression triggers the selective elimination of weakly integrated synapses

(2013) J. S. Wiegert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

AMPA receptor pHluorin-GluA2 reports NMDA receptor-induced intracellular acidification in hippocampal neurons

(2013) M. Rathje et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metabotropic NMDA receptor function is required for NMDA receptor-dependent long-term depression

(2013) S. Nabavi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Structural plasticity upon learning: regulation and functions

(2012) Pico Caroni et al.   NATURE REVIEWS NEUROSCIENCE

Haploinsufficiency of Cyfip1 Produces Fragile X-Like Phenotypes in Mice

(2012) Ozlem Bozdagi et al.   PLoS One

Synapse-specific and size-dependent mechanisms of spine structural plasticity accompanying synaptic weakening

(2012) Won Chan Oh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rescue of dendritic spine phenotype in Fmr1 KO mice with the mGluR5 antagonist AFQ056/Mavoglurant

(2012) Andreea S. Pop et al.   PSYCHOPHARMACOLOGY

Structural plasticity of dendritic spines

(2011) Miquel Bosch et al.   CURRENT OPINION IN NEUROBIOLOGY

AMPA receptor subunit GluR1 (GluA1) serine-845 site is involved in synaptic depression but not in spine shrinkage associated with chemical long-term depression

(2011) Kaiwen He et al.   JOURNAL OF NEUROPHYSIOLOGY

mGluR and NMDAR activation internalize distinct populations of AMPARs

(2011) Tanya M. Casimiro et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Loss of the Fragile X Mental Retardation Protein Decouples Metabotropic Glutamate Receptor Dependent Priming of Long-Term Potentiation From Protein Synthesis

(2010) Benjamin D. Auerbach et al.   JOURNAL OF NEUROPHYSIOLOGY

Dysregulation of mTOR Signaling in Fragile X Syndrome

(2010) A. Sharma et al.   JOURNAL OF NEUROSCIENCE

Hypersensitivity to mGluR5 and ERK1/2 Leads to Excessive Protein Synthesis in the Hippocampus of a Mouse Model of Fragile X Syndrome

(2010) E. K. Osterweil et al.   JOURNAL OF NEUROSCIENCE

mTOR signaling: At the crossroads of plasticity, memory and disease

(2009) Charles A. Hoeffer et al.   TRENDS IN NEUROSCIENCES

Homer Interactions Are Necessary for Metabotropic Glutamate Receptor-Induced Long-Term Depression and Translational Activation

(2008) J. A. Ronesi et al.   JOURNAL OF NEUROSCIENCE

The magnitude of hippocampal long term depression depends on the synaptic location of activated NR2-containing N-methyl-d-aspartate receptors

(2008) M. Kollen et al.   NEUROSCIENCE

Protein Synthesis and Neurotrophin-Dependent Structural Plasticity of Single Dendritic Spines

(2008) J.-i. Tanaka et al.   SCIENCE