Nonsense‐mediated decay factor SMG7 sensitizes cells to TNFα‐induced apoptosis via CYLD tumor suppressor and the noncoding oncogene Pvt1

Hacking the Cancer Genome: Profiling Therapeutically Actionable Long Non-coding RNAs Using CRISPR-Cas9 Screening

(2019) Roberta Esposito et al.   CANCER CELL

GTP Cyclohydrolase 1/Tetrahydrobiopterin Counteract Ferroptosis through Lipid Remodeling

(2019) Vanessa A. N. Kraft et al.   ACS Central Science

Genome-wide Scan Identifies Role for AOX1 in Prostate Cancer Survival

(2018) Weiqiang Li et al.   EUROPEAN UROLOGY

Double-slit photoelectron interference in strong-field ionization of the neon dimer

(2018) Maksim Kunitski et al.   Nature Communications

Proteomic Landscape of Patient-Derived CD4+ T Cells in Recent-Onset Type 1 Diabetes

(2017) Marlen F. Lepper et al.   JOURNAL OF PROTEOME RESEARCH

An atlas of human long non-coding RNAs with accurate 5′ ends

(2017) Chung-Chau Hon et al.   NATURE

Salmon provides fast and bias-aware quantification of transcript expression

(2017) Rob Patro et al.   NATURE METHODS

Identification of nonsense-mediated mRNA decay pathway as a critical regulator of p53 isoform β

(2017) Lauren E. Cowen et al.   Scientific Reports

Targeting the NF-κB pathway in prostate cancer: a promising therapeutic approach?

(2016) Daniela Verzella et al.   CURRENT DRUG TARGETS

Cell spheroids: the new frontiers in in vitro models for cancer drug validation

(2016) Maria Chatzinikolaidou   DRUG DISCOVERY TODAY

miR-20a induces cisplatin resistance of a human gastric cancer cell line via targeting CYLD

(2016) Mingxia Zhu et al.   Molecular Medicine Reports

NF-κB-HOTAIR axis links DNA damage response, chemoresistance and cellular senescence in ovarian cancer

(2016) A R Özeş et al.   ONCOGENE

Nonsense-mediated mRNA decay: novel mechanistic insights and biological impact

(2016) Evangelos D. Karousis et al.   Wiley Interdisciplinary Reviews-RNA

SMG7 is a critical regulator of p53 stability and function in DNA damage stress response

(2016) Hongwei Luo et al.   Cell Discovery

MicroRNA-362-5p promotes tumor growth and metastasis by targeting CYLD in hepatocellular carcinoma

(2015) Fang Ni et al.   CANCER LETTERS

Tumor necrosis factor, tumor necrosis factor inhibition, and cancer risk

(2015) Hervé Lebrec et al.   CURRENT MEDICAL RESEARCH AND OPINION

Extending the Limits of Quantitative Proteome Profiling with Data-Independent Acquisition and Application to Acetaminophen-Treated Three-Dimensional Liver Microtissues

(2015) Roland Bruderer et al.   MOLECULAR & CELLULAR PROTEOMICS

Highly specific epigenome editing by CRISPR-Cas9 repressors for silencing of distal regulatory elements

(2015) Pratiksha I Thakore et al.   NATURE METHODS

Pan-cancer transcriptome analysis reveals long noncoding RNAs with conserved function

(2015) Christopher R Cabanski et al.   RNA Biology

Expression of TNF-α and CD44 is implicated in poor prognosis, cancer cell invasion, metastasis and resistance to the sunitinib treatment in clear cell renal cell carcinomas

(2014) Shuji Mikami et al.   INTERNATIONAL JOURNAL OF CANCER

PVT1 dependence in cancer with MYC copy-number increase

(2014) Yuen-Yi Tseng et al.   NATURE

Role of the lncRNA-p53 regulatory network in cancer

(2014) A. Zhang et al.   Journal of Molecular Cell Biology

CYLD controls c-MYC expression through the JNK-dependent signaling pathway in hepatocellular carcinoma

(2013) Rajeswara Rao Pannem et al.   CARCINOGENESIS

The SMG5-SMG7 heterodimer directly recruits the CCR4-NOT deadenylase complex to mRNAs containing nonsense codons via interaction with POP2

(2013) B. Loh et al.   GENES & DEVELOPMENT

An unusual arrangement of two 14-3-3-like domains in the SMG5-SMG7 heterodimer is required for efficient nonsense-mediated mRNA decay

(2013) S. Jonas et al.   GENES & DEVELOPMENT

The Noncoding RNA MALAT1 Is a Critical Regulator of the Metastasis Phenotype of Lung Cancer Cells

(2012) T. Gutschner et al.   CANCER RESEARCH

Myoblasts Inhibit Prostate Cancer Growth by Paracrine Secretion of Tumor Necrosis Factor-α

(2012) Meline Nogueira Lucena Stölting et al.   JOURNAL OF UROLOGY

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

(2012) Jordi Barretina et al.   NATURE

Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks

(2012) Cole Trapnell et al.   Nature Protocols

MicroRNA and transcription factor co-regulatory network analysis reveals miR-19 inhibits CYLD in T-cell acute lymphoblastic leukemia

(2012) Huashan Ye et al.   NUCLEIC ACIDS RESEARCH

Cancer syndromes and therapy by stop-codon readthrough

(2012) Renata Bordeira-Carriço et al.   TRENDS IN MOLECULAR MEDICINE

The functional role of long non-coding RNA in human carcinomas

(2011) Ewan A Gibb et al.   Molecular Cancer

Long noncoding RNAs and human disease

(2011) Orly Wapinski et al.   TRENDS IN CELL BIOLOGY

Tumor Necrosis Factor Receptor Expression and Signaling in Renal Cell Carcinoma

(2010) Rafia S. Al-Lamki et al.   AMERICAN JOURNAL OF PATHOLOGY

NMD: RNA biology meets human genetic medicine

(2010) Madhuri Bhuvanagiri et al.   BIOCHEMICAL JOURNAL

Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis

(2010) Rajnish A. Gupta et al.   NATURE

CYLD: a tumor suppressor deubiquitinase regulating NF-κB activation and diverse biological processes

(2009) S-C Sun   CELL DEATH AND DIFFERENTIATION

Universal sample preparation method for proteome analysis

(2009) Jacek R Wiśniewski et al.   NATURE METHODS

A Human snoRNA with MicroRNA-Like Functions

(2008) Christine Ender et al.   MOLECULAR CELL

Pvt1-encoded microRNAs in oncogenesis

(2008) Gabriele B Beck-Engeser et al.   Retrovirology