Fibroblast growth factor‐2, derived from cancer‐associated fibroblasts, stimulates growth and progression of human breast cancer cells via FGFR1 signaling

Approaches to treat immune hot, altered and cold tumours with combination immunotherapies

(2019) Jérôme Galon et al.   NATURE REVIEWS DRUG DISCOVERY

GPER Mediates a Feedforward FGF2/FGFR1 Paracrine Activation Coupling CAFs to Cancer Cells Toward Breast Tumor Progression

(2019) Maria Francesca Santolla et al.   Cells

Effect of FGF/FGFR pathway blocking on lung adenocarcinoma and its cancer‐associated fibroblasts

(2019) Ahmed E. Hegab et al.   JOURNAL OF PATHOLOGY

CD26 expression is attenuated by TGF‐β and SDF‐1 autocrine signaling on stromal myofibroblasts in human breast cancers

(2019) Yoshihiro Mezawa et al.   Cancer Medicine

The biological and clinical significance of stromal-epithelial interactions in breast cancer

(2017) Robert McCuaig et al.   PATHOLOGY

Cancer-associated fibroblasts secrete FGF-1 to promote ovarian proliferation, migration, and invasion through the activation of FGF-1/FGFR4 signaling

(2017) Yuanzhen Sun et al.   TUMOR BIOLOGY

Covalent Targeting of Fibroblast Growth Factor Receptor Inhibits Metastatic Breast Cancer

(2016) W. S. Brown et al.   MOLECULAR CANCER THERAPEUTICS

Association between transforming growth factor-β1 expression and the clinical features of triple negative breast cancer

(2016) MING-JIAN DING et al.   Oncology Letters

Cytoplasmic cyclin D1 regulates cell invasion and metastasis through the phosphorylation of paxillin

(2016) Noel P. Fusté et al.   Nature Communications

Myoepithelial Cell Differentiation Markers in Ductal Carcinoma in Situ Progression

(2015) Tanya D. Russell et al.   AMERICAN JOURNAL OF PATHOLOGY

Stromal gene expression defines poor-prognosis subtypes in colorectal cancer

(2015) Alexandre Calon et al.   NATURE GENETICS

Fibroblast surface-associated FGF-2 promotes contact-dependent colorectal cancer cell migration and invasion through FGFR-SRC signaling and integrin αvβ5-mediated adhesion

(2015) Sarah Knuchel et al.   Oncotarget

Metabolic Reprogramming of Stromal Fibroblasts through p62-mTORC1 Signaling Promotes Inflammation and Tumorigenesis

(2014) Tania Valencia et al.   CANCER CELL

Cancer-associated fibroblasts induce epithelial–mesenchymal transition of breast cancer cells through paracrine TGF-β signalling

(2013) Y Yu et al.   BRITISH JOURNAL OF CANCER

Human breast cancer associated fibroblasts exhibit subtype specific gene expression profiles

(2012) Julia Tchou et al.   BMC Medical Genomics

Dependency of Colorectal Cancer on a TGF-β-Driven Program in Stromal Cells for Metastasis Initiation

(2012) Alexandre Calon et al.   CANCER CELL

Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment

(2012) Douglas Hanahan et al.   CANCER CELL

CCL2 Mediates Cross-talk between Cancer Cells and Stromal Fibroblasts That Regulates Breast Cancer Stem Cells

(2012) A. Tsuyada et al.   CANCER RESEARCH

FGFR1 cleavage and nuclear translocation regulates breast cancer cell behavior

(2012) Athina-Myrto Chioni et al.   JOURNAL OF CELL BIOLOGY

Functional Screen of Paracrine Signals in Breast Carcinoma Fibroblasts

(2012) Gui Su et al.   PLoS One

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Role of TGF-β and the Tumor Microenvironment During Mammary Tumorigenesis

(2011) MOLLY A. TAYLOR et al.   GENE EXPRESSION

Role of cancer-associated fibroblasts in breast cancer development and prognosis

(2011) Abdelilah Aboussekhra   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Breast Cancer Cells Induce Cancer-Associated Fibroblasts to Secrete Hepatocyte Growth Factor to Enhance Breast Tumorigenesis

(2011) Shiaw-Wei Tyan et al.   PLoS One

Tumor–stroma ratio in the primary tumor is a prognostic factor in early breast cancer patients, especially in triple-negative carcinoma patients

(2010) Esther M. de Kruijf et al.   BREAST CANCER RESEARCH AND TREATMENT

Cancer-Associated Fibroblasts Are Activated in Incipient Neoplasia to Orchestrate Tumor-Promoting Inflammation in an NF-κB-Dependent Manner

(2010) Neta Erez et al.   CANCER CELL

FGFR1 Amplification Drives Endocrine Therapy Resistance and Is a Therapeutic Target in Breast Cancer

(2010) N. Turner et al.   CANCER RESEARCH

Reciprocal Activation of Prostate Cancer Cells and Cancer-Associated Fibroblasts Stimulates Epithelial-Mesenchymal Transition and Cancer Stemness

(2010) E. Giannoni et al.   CANCER RESEARCH

Autophagy in cancer associated fibroblasts promotes tumor cell survival

(2010) Ubaldo E. Martinez-Outschoorn et al.   CELL CYCLE

Stromal fibroblasts from the interface zone of human breast carcinomas induce an epithelial-mesenchymal transition-like state in breast cancer cells in vitro

(2010) M.-Q. Gao et al.   JOURNAL OF CELL SCIENCE

Interactions with Fibroblasts Are Distinct in Basal-Like and Luminal Breast Cancers

(2010) J. T. Camp et al.   MOLECULAR CANCER RESEARCH

Carcinoma-associated fibroblasts activate progesterone receptors and induce hormone independent mammary tumor growth: A role for the FGF-2/FGFR-2 axis

(2008) Sebastián Giulianelli et al.   INTERNATIONAL JOURNAL OF CANCER

Podoplanin expression by cancer associated fibroblasts predicts poor prognosis of lung adenocarcinoma

(2008) Akikazu Kawase et al.   INTERNATIONAL JOURNAL OF CANCER

FGF-1-induced matrix metalloproteinase-9 expression in breast cancer cells is mediated by increased activities of NF-κB and activating protein-1

(2007) Gina Lungu et al.   MOLECULAR CARCINOGENESIS