Article
Chemistry, Multidisciplinary
Jan Janesch, Markus Bacher, Sidhant Padhi, Thomas Rosenau, Wolfgang Gindl-Altmutter, Christian Hansmann
Summary: In this study, a novel approach for the preparation of renewable alkyd resins using vegetable triglycerides, glycerol, and FDME was proposed. The results showed that increasing the content of FDME led to resins with higher molecular weight and viscosity, and successfully formed solid film coatings.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2023)
Article
Chemistry, Analytical
Lorenzo Vannoni, Silvia Pizzimenti, Giulia Caroti, Jacopo La Nasa, Celia Duce, Ilaria Bonaduce
Summary: In this study, a methodological approach for investigating the molecular features of oil paint layers upon curing was implemented using a simplified model of oil binder. Various mass spectrometric techniques were used to analyse the compounds produced during natural aging, revealing the crucial differences in stability between paint layers containing different pigments, particularly related to the cross-linked fraction.
MICROCHEMICAL JOURNAL
(2022)
Article
Polymer Science
Antonella Hadzich, Santiago Flores, Ashley E. Masucci, Enrique D. Gomez, G. Alexander Gross
Summary: NMR spectroscopy and GPC were used to characterize the differences in chemical structure, molecular distribution, and dispersity of oil-based and fatty acid-based alkyd resins. Important structural differences were observed by comparing two different synthesis methods. GPC analysis revealed that alkyd resins synthesized with the fatty acid process can have homogeneous and high molecular weights.
Article
Chemistry, Physical
Yong-A Choe, Su-Il Kim, Kyong-Sik Ju
Summary: This study evaluated the use of acrylic pimaric acid (APA) as a bio-based substitute for the aromatic diacid monomer in high oil length alkyd resins. The results showed that HOARs containing 9% APA exhibited excellent gloss, pencil hardness, impact strength, and alkaline resistance. Moreover, the price of these resins decreased by about 20% compared to conventional AR, making them a valuable binder in the field of protective paint.
CHEMICAL PHYSICS LETTERS
(2022)
Article
Chemistry, Applied
Laura M. Orozco, Sandra Cardona, Claudia Gomez, Helen Inciarte, Yurany Villada, Luis Rios
Summary: This study suggests using KHSO4 as a re-usable catalyst in the dehydration of castor oil, which offers desired yields, easy separation, and low environmental impact. The catalyst showed good stability in five consecutive experiments. Partial transformation of KHSO4 into K2SO4 and K2S2O7 during the reaction led to a decrease in acidity.
PROGRESS IN ORGANIC COATINGS
(2021)
Article
Chemistry, Applied
C. Hejjaj, A. AitAghzzaf, N. Scharnagl, M. L. Zheludkevich, R. Hakkou, C. B. Fischer
Summary: The novel hybrid phosphate pigment 6-amino hexanoic acid (6-AHA) intercalated in layered aluminum dihydrogen tripolyphosphate (ATP-6-AHA) was successfully embedded in an alkyd coating on low carbon steel, demonstrating superior corrosion protection. Various tests revealed the formation of a protective film on the coated surface, effectively preventing corrosion of the steel.
PROGRESS IN ORGANIC COATINGS
(2021)
Article
Plant Sciences
Joseph Lee, Mei Wang, Jianping Zhao, Zulfiqar Ali, Mohammed F. Hawwal, Ikhlas A. Khan
Summary: Copaiba oil-resin has gained popularity worldwide over recent years due to its medicinal properties and industrial applications. However, there is a lack of standardization and issues with product adulteration for maximum profits. This study analyzed forty copaiba oil-resin samples using GC/MS and found six characteristic compounds present in varying concentrations, except for the commercial samples. Compositional patterns were observed, and principal component analysis (PCA) showed distinct groups corresponding to sample origin, with commercial samples detected as outliers and showing adulteration with soybean oil.
Article
Environmental Sciences
Ian J. Vander Meulen, Danna M. Schock, Fardausi Akhter, Lukas J. Mundy, Kristin M. Eccles, Catherine Soos, Kerry M. Peru, Dena W. McMartin, John V. Headley, Bruce D. Pauli
Summary: This study investigated the occurrence and characteristics of naphthenic acids (NAs) in boreal wetlands in the Athabasca oil sands region of Alberta, Canada. The results showed that NAs in surface waters were mainly derived from oil sands deposits, but similar patterns were also observed in undeveloped natural wetlands.
ENVIRONMENTAL POLLUTION
(2023)
Article
Chemistry, Multidisciplinary
Corinne A. Lutomski, Tarick J. El-Baba, Joshua D. Hinkle, Idlir Liko, Jack L. Bennett, Neha V. Kalmankar, Andrew Dolan, Carla Kirschbaum, Kim Greis, Leonhard H. Urner, Parth Kapoor, Hsin-Yung Yen, Kevin Pagel, Christopher Mullen, John E. P. Syka, Carol V. Robinson
Summary: By using an infrared laser in a high-pressure linear ion trap, researchers were able to remove detergent micelles and obtain good sequence coverage for membrane proteins and their complexes through top-down mass spectrometry.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Materials Science, Multidisciplinary
Anthony Glenn, Alan T. Jensen, Fabricio Machado
Summary: The study synthesized chia air-dry alkyd resins and confirmed the presence of functional groups through FTIR spectroscopy and NMR. Various experiments were conducted to evaluate the impact of process parameters, with catalysts playing a fundamental role in reducing reaction time and promoting formation of monoglycerides.
ACS APPLIED POLYMER MATERIALS
(2021)
Article
Polymer Science
Parineeta Das, Namita Sharma, Amrit Puzari, Dilip Kumar Kakati, Nirmala Devi
Summary: Neem seed oil was extracted using petroleum ether and used to synthesize alkyd resins, with the addition of maleic anhydride improving their performance in various surface coating applications. The resins showed excellent corrosion protection on mild steel plates and higher maleic anhydride content resulted in superior properties. The synthesized resins have great potential for marine vessel finishes to resist salt corrosion.
Article
Polymer Science
V. S. Benitha, K. Jeyasubramanian, B. Vijayakumari, V. S. Prabhin
Summary: The advent of organic polyester alkyd resin has revolutionized the coating industry, and the incorporation of CaF2 Nps in the polyester alkyd coating provides good antibacterial and anticorrosive properties, making it suitable for multifunctional coating applications.
JOURNAL OF APPLIED POLYMER SCIENCE
(2023)
Article
Materials Science, Multidisciplinary
Miroslav Kohl, Fouzy Alafid, Karolina Bostikova, Anna Krejcova, Stanislav Slang, Dominik Reznicek, Radim Hrdina, Andrea Kalendova
Summary: This study investigates the properties and testing of newly prepared organic pigments based on melamine cyanurate with magnesium or zinc cations. The synthesized pigments showed anticorrosive properties, with differences in performance depending on the structure of the pigments. The highest anticorrosion efficiency was achieved by the pigment based on melamine cyanurate with magnesium cation.
Article
Optics
Siwen Wang, Grite L. Abma, Peter Kruger, Andre van Roij, Michiel Balster, Niek Janssen, Daniel A. Horke
Summary: The vaporisation step is a major obstacle in the gas-phase study of larger molecular systems. Laser-induced acoustic desorption (LIAD) sources offer a promising approach for intact introduction of sample molecules into the gas-phase. In this study, we compare nanosecond pulsed and continuous desorption lasers for the first time, using adenine as a prototypical biological molecule. Our observations reveal different desorption mechanisms but no fragmentation of the target molecule unless excessive desorption energy is applied. This makes LIAD a powerful tool for gas-phase techniques requiring high density and high purity samples.
EUROPEAN PHYSICAL JOURNAL D
(2022)
Article
Polymer Science
Fatimah Ali M. Al-Zahrani, Long Lin, Hamada Abd El-Wahab
Summary: By partially substituting glycerol with 1,3,5-tris-(2-hydroxyethyl) cyanuric acid, new modified alkyd resins with different oil length and hydroxyl content can be produced. These modified alkyd resins exhibit improved drying qualities and corrosion resistance.
Article
Chemistry, Physical
Andrea Basagni, Veronica Torresan, Pasquina Marzola, Marcela B. Fernandez van Raap, Luca Nodari, Vincenzo Amendola
Summary: Metastable alloy nanoparticles with complex ultrastructure and dynamic evolution have potential applications in various fields such as photocatalysis and nanomedicine. In this study, metastable Au-Fe alloy nanoparticles were successfully synthesized by laser ablation in liquid, and their properties were characterized using different techniques.
FARADAY DISCUSSIONS
(2023)
Article
Chemistry, Analytical
Francesca Sabatini, Iacopo Corsi, Alessio Ceccarini, Marco Brillanti, Maria Perla Colombini, Ilaria Bonaduce
Summary: This paper investigates the characterization and identification of metal-free leather using pyrolysis-gas chromatography-mass spectrometry (Py-GC-MS). Thirty-three bovine split leather samples tanned with various metal-free tanning agents were analyzed, and pyrolytic markers were determined in reference materials, intermediates, and end-products. Evolved gas analysis coupled with mass spectrometry was used to compare the thermodegradative profiles of metal-free leathers and chromium tanned leather.
JOURNAL OF ANALYTICAL AND APPLIED PYROLYSIS
(2023)
Article
Spectroscopy
Michele Cassetta, Beatrice Giannetta, Francesco Enrichi, Claudio Zaccone, Gino Mariotto, Marco Giarola, Luca Nodari, Marco Zanatta, Nicola Daldosso
Summary: This study examines the effects of alkali vs iron ratio on the properties of synthetic basaltic glasses using Raman spectroscopy and calorimetry. The results show that changes in this ratio alter the glass transition interval and the structure of the glass. The study also reveals that increasing the alkali vs iron content results in a harder elastic medium without changing its nature.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2023)
Editorial Material
Chemistry, Analytical
B. Campanella, F. Poggialini, S. Legnaioli, B. Cocciaro, G. Lorenzetti, S. Raneri, V. Palleschi
ANALYTICA CHIMICA ACTA
(2023)
Article
Agricultural Engineering
Jose Gonzalez-Rivera, Beatrice Campanella, Elena Pulidori, Emilia Bramanti, Maria Rosaria Tine, Luca Bernazzani, Massimo Onor, Paolo Barberi, Celia Duce, Carlo Ferrari
Summary: Novel green extraction method (US-IMWAE) using simultaneous ultrasound and microwave irradiation allows for full exploitation of aromatic herbs while minimizing energy consumption and extraction cost. This method has successfully yielded essential oils with appealing composition profiles for cosmetic and medical industries, as well as valuable solid residues for alternative fuel production.
INDUSTRIAL CROPS AND PRODUCTS
(2023)
Article
Chemistry, Analytical
Francesca De Falco, Tommaso Nacci, Lee Durndell, Richard C. Thompson, Ilaria Degano, Francesca Modugno
Summary: Biodegradable polymers offer a potential solution to plastic pollution, but assessing their degradation process and chemical composition is crucial. This study used Py-GC-MS and EGA-MS techniques to analyze the thermal degradation profiles, main m/z ions, and pyrolysis markers of different biodegradable polymers and commercial products. The presence of additives and impurities was also identified. These findings contribute to a better understanding of the degradation process and chemical composition of biodegradable polymers in the environment.
JOURNAL OF ANALYTICAL AND APPLIED PYROLYSIS
(2023)
Article
Polymer Science
Rosa Costantini, Luca Nodari, Jacopo La Nasa, Francesca Modugno, Lucia Bonasera, Sara Rago, Alfonso Zoleo, Stefano Legnaioli, Patrizia Tomasin
Summary: This study investigates the instability of polyurethane foam used in artworks, which requires careful conservation strategies. Various analytical techniques were used to characterize the main components and additives of the foam. Morphological changes and harmful environmental factors were also studied. The findings provide important insights for preventive conservation of these artworks.
Article
Chemistry, Multidisciplinary
Francesco Poggialini, Stefano Legnaioli, Beatrice Campanella, Bruno Cocciaro, Giulia Lorenzetti, Simona Raneri, Vincenzo Palleschi
Summary: This paper discusses the issues related to determining the limits of detection (LOD) in laser-induced breakdown spectroscopy (LIBS) analytical applications. It illustrates the derivation of the commonly used '3-sigma over slope' rule and its evolution towards the new official definition recently adopted by the International Union of Pure and Applied Chemistry (IUPAC). Methods for extending LOD calculation to LIBS multivariate analysis are also discussed, using the detection of Cu traces in cast iron samples by LIBS as an example.
APPLIED SCIENCES-BASEL
(2023)
Article
Biochemistry & Molecular Biology
Beatrice Campanella, Stefano Legnaioli, Massimo Onor, Edoardo Benedetti, Emilia Bramanti
Summary: Saliva is a sample that can be easily collected and contains a wealth of biochemical information related to an individual's health status. The fast and straightforward analysis of saliva using vibrational spectroscopy provides a good basis for large-scale preclinical studies. This study explored the effects of saliva collection (spitting/swab) and processing (deproteinization procedures) and found that special care is needed when using swabs due to the significant interaction between the polymeric material and saliva components. Additionally, analyzing saliva before and after deproteinization by FTIR and Raman spectroscopy provides complementary biological information.
Article
Humanities, Multidisciplinary
Lucrezia Milillo, Marei Hacke, Sara Norrehed, Ilaria Degano, Francesca Gherardi, Ellinor Gunnarsson
Summary: This study is the first scientific research on khipu dyes and inorganic mordants and auxiliaries, providing a new approach to understanding the meaningful materiality, technology, and colours of khipus. Khipus are often described as Andean knotted records, but they are more than just complex knotted cords: a significant amount of encoded information resides in the incredible colours of khipus.
Article
Polymer Science
Francesca Sabatini, Silvia Pizzimenti, Irene Bargagli, Ilaria Degano, Celia Duce, Laura Cartechini, Francesca Modugno, Francesca Rosi
Summary: In this study, the chemical and thermal properties of an ABS-based polymer and its photodegradation process were investigated through various analytical techniques. LEGO® building blocks were chosen as the sample for studying ABS properties and subjected to UV-Vis photo-oxidative-accelerated ageing. The multimodal approach provided new evidence on the degradation pathway of ABS and the feasibility of using external reflection FT-IR spectroscopy as a non-invasive portable tool for monitoring the conservation of plastic museum objects in-situ.
Article
Humanities, Multidisciplinary
Francesca Sabatini, Jacopo La Nasa, Ilaria Degano, Beatrice Campanella, Stefano Legnaioli, Ilaria Saccani, Francesca Modugno, Marta Manso
Summary: In recent years, there has been a growing recognition of the social and cultural significance of street art murals, leading to a focus on preserving representative modern urban murals. The UBUNTU mural is an interesting case study, as it has undergone significant changes in appearance over a few years due to exposure to sunlight and environmental factors. Analysis of collected samples has revealed the painting materials used by the artist and the aging phenomena responsible for the fading colors of the mural.
Article
Polymer Science
Elisa Della Latta, Francesca Sabatini, Cosimo Micheletti, Marco Carlotti, Francesca Martini, Francesca Nardelli, Antonella Battisti, Ilaria Degano, Marco Geppi, Andrea Pucci, Svenja Pohl, Guido Kickelbick
Summary: In this study, flexible luminescent solar concentrators (LSCs) with a size of 5 x 5 cm(2) were prepared by integrating a reactive perylene bisimide fluorophore (FC546) into a polysiloxane network. The LSCs exhibited higher thermal and light stability, as well as superior device efficiency, compared to other similar-sized flexible LSC systems.
Article
Chemistry, Analytical
Michelle Buoso, Beatrice Campanella, Massimo Onor, Emanuela Pitzalis, Alessandro D'Ulivo
Summary: The use of BH intermediates as derivatization reagents significantly improves the tolerance to interference from transition metal ions in the generation of SbH3 and BiH3, and shows high tolerance in a wide range of acidity. The method has been successfully applied to the determination of Sb and Bi in complex samples, providing further understanding of the chemical behavior of borohydrides.
JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY
(2024)
Article
Chemistry, Applied
Adele Ferretti, Ilaria Degano, Stefano Legnaioli, Beatrice Campanella, Aurora Sainati, Maria Perla Colombini
Summary: Throughout history, human beings have used writing as a means of communication and expression. This study focuses on the analysis of red inks produced in France during the late 19th to early 20th century. By utilizing various analytical techniques, the researchers were able to identify the dyes, pigments, binders, and additives used in these inks. The findings provide valuable insights into the early days of the synthetic dye industry.
Article
Chemistry, Analytical
Michel Rocha Baqueta, Augusto Cesar Costa-Santos, Ana Paula Rebellato, Gisele Marcondes Luz, Juliana Azevedo Lima Pallone, Federico Marini, Alexsandro Lara Teixeira, Douglas N. Rutledge, Patricia Valderrama
Summary: This study reports the essential element composition of new Brazilian Canephora coffees and applies chemometric tools for analysis. The results demonstrate the suitability of this method for origin and species discrimination based on the inorganic fraction of coffee.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Mengjie Li, Jiapeng Wang, You Zhou, Yang Chen, Lingying Xia
Summary: A novel photoelectrochemical biosensor based on gold nanoparticles and specific structures was developed for highly sensitive detection of mercury ion. The multiple sandwich structures hindered electron supply and light harvesting, resulting in a weakened PEC signal, while the specific structures extinguished the PEC signal, enabling quantitative detection of Hg2+. The sensor exhibited high selectivity and stability, with potential applications in environmental detection, biological analysis, and medical research.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Mohamed A. Korany, Rasha M. Youssef, Marwa A. A. Ragab, Mostafa A. Afify
Summary: A stability-indicating fit-for-purpose method was developed for the determination of HC, TL, and PS in syrup dosage form. The method successfully separated CL from THY and quantified the analytes using HPLC-DAD. The robustness of the method was assessed through statistical analysis and self-validation.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Lingling Lin, Minyu Li, Ping Li, Chenqing Ye, Huanglong Zhuang, Shaohuang Weng, Feng Chen
Summary: This study developed a highly sensitive and selective electrochemical sensor for simultaneous detection of dopamine and uric acid. The sensor exhibited excellent anti-interference and stability, and could accurately measure dopamine and uric acid in human urine samples.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Peifang Chen, Caiyun Jiang, Zhouping Wang, Hong-zhen Lian, Xiaoyuan Ma
Summary: In this study, a high-performance SERS-active aptasensor was successfully developed for the quantitative analysis of AFB1 in cereal grains, which is of great significance in the field of food safety.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
E. Abas, C. Marina-Montes, C. Perez-Marin, J. Puimedon, J. Anzano
Summary: This study conducted a comprehensive measurement of natural and anthropogenic radionuclides in soil, water, and air in different locations around Deception Island in Antarctica. The results revealed significant levels of 210Pb and anthropogenic 137Cs in soil samples near old human settlements and facilities, as well as detectable levels of 137Cs and 60Co in water samples from old hunting areas. The findings also suggested potential resuspension processes based on higher-than-expected air quality results.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Joao Franciso Allochio, Nayara A. dos Santos, Nathalia dos S. Conceicao, Clara S. D. Baptista, Keyller B. Borges, Valdemar Lacerda Jr, Wanderson Roma
Summary: This study developed a fiber spray ionization mass spectrometry (FSI-MS) method, which shows great potential in detecting illicit drugs. Compared with paper spray ionization mass spectrometry (PSI-MS), FSI-MS demonstrates higher sensitivity in COC detection.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Dina A. Ahmed, Ola G. Hussein, Mamdouh R. Rezk, Mohamed Abdelkawy, Yasmin Rostom
Summary: The main goal of this study was to develop two green chromatographic techniques, HPLC and TLC, for the determination of alcaftadine (ALF) in pharmaceutical formulation and biological samples. The developed HPLC technique showed high efficiency and minimal environmental impact, successfully identifying ALF in the presence of its degradate. The TLC method provided a stability indicating study for ALF and was determined to be safe, green, and eco-friendly.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Abdullah Taner Bisgin
Summary: A green, speedy, and handy method for separation and determination of four commonly used food colorants was established using vortex assisted sequential-simultaneous liquid phase micro-extraction (VA-SS-LPME). The method does not require any instrumental chromatographic techniques. The procedure includes sequential separation steps using different extractants and simultaneous UV-vis spectrophotometric determination steps. The method is environmentally friendly and applicable for determination of colorants in food and pharmaceuticals.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Yifan Zhang, Tong Zhang, Wenjing Ba, Li Liu, Yuan Rao, Xiaodan Zhang, Hanhan Zhang, Xiu Jin
Summary: This paper proposes a novel spectral transfer modelling method based on neural network architecture searching for the asymptomatic prediction of Akizuki pear cork spot disorder. The experiments show that the model by this method is more effective, achieving an accuracy of 82.61%.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Krzysztof Greda, Maja Welna, Anna Szymczycha-Madeja, Pawel Pohl
Summary: For the first time, a dispersive micro-solid phase extraction (D-mu SPE) based on graphene oxide was used for the ultrasensitive determination of Cd. With this method, Cd can be efficiently extracted from a mixture of alkali and alkaline earth metals without the need for an elution step. The combination of D-mu SPE and SAGD OES significantly reduces matrix effects and improves the tolerance of Cd to alkali metals. The method shows simplicity in the measurement system and the commercially available nanosorbent used.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
P. K. Fathima Anjila, G. R. Tharani, Anand Sundaramoorthy, Venkat Kumar Shanmugam, Karthikeyan Subramani, Shanmugavel Chinnathambi, Ganesh N. Pandian, Vimala Raghavan, Andrews Nirmala Grace, Singaravelu Ganesan, Mangaiyarkarasi Rajendiran
Summary: This work proposes a rapid and sensitive spectroscopic method for detecting melamine in food products using rare-earth Terbium-doped Graphene Quantum Dots (Tb-GQDs) synthesized by microwave and simple chemical conjugation methods. The synthesized Tb-GQDs show a spherical shape with a size of approximately 6 nm and a quantum yield of 52%. The maximum detection limit for melamine concentration in milk and milk products is found to be 0.31 μM. The dual emitting Tb-GQDs provide a sensitive and effective platform for real-time detection of melamine in food samples, particularly in milk, and show promising potential in the food industry.
MICROCHEMICAL JOURNAL
(2024)
Review
Chemistry, Analytical
Piyush Dey, Mandeep Kaur, Akhil Khajuria, Dilmeet Kaur, Manpreet Singh, Hema Kumari Alajangi, Neha Singla, Gurpal Singh, Ravi Pratap Barnwal
Summary: Environmental issues, such as the uncontrolled release of dangerous pollutants, have significant impacts on human health. Traditional methods for detecting pollutants require specialized personnel and equipment, but nanotechnology has improved the performance of biosensors. This article discusses the use of nanotechnology in pollutant detection and the associated techniques.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Sa Dong, Qiuyun Shi, Lingjun Guan, Yulong Wang, Pengyan Liu, Cunzheng Zhang, Jianguo Feng
Summary: In this study, a highly sensitive indirect competitive chemiluminescence enzyme immunoassay (icCLEIA) method was developed for the determination of sodium pentachlorophenolate (PCP-Na) and its metabolite pentachlorophenol (PCP). The method showed high specificity and affinity with a detection limit of 0.0032 ng/mL for PCP-Na and 0.0192 ng/mL for PCP. The method had no cross reaction with other chlorophenols compounds except for PCP. The average recoveries in chicken, pork and fish samples were 81.3-105.8% with low coefficient of variation (CV).
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Palaniappan Ilayaraja, Murugan Manivannan, Paramasivam Parthiban
Summary: Nirmatrelvir, an antiviral drug used for the treatment of COVID-19, has been recommended by the World Health Organization. We developed an optimized analytical method for the quantification of Nirmatrelvir and its products, with high sensitivity and a wide linear range. The method also meets the requirements for greenness evaluation.
MICROCHEMICAL JOURNAL
(2024)
