Evidence for inflammasome activation in the brain of mucopolysaccharidosis type II mice

Haematopoietic stem cell gene therapy with IL ‐1Ra rescues cognitive loss in mucopolysaccharidosis IIIA

(2020) Helen Parker et al.   EMBO Molecular Medicine

The role of lysosomal cysteine cathepsins in NLRP3 inflammasome activation

(2019) Rhiannon I. Campden et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

The role of astroglia in Alzheimer's disease: pathophysiology and clinical implications

(2019) Amaia M Arranz et al.   LANCET NEUROLOGY

Caspase-1 activity influences juvenile Batten disease (CLN3) pathogenesis

(2018) Maria Burkovetskaya et al.   JOURNAL OF NEUROCHEMISTRY

Cathepsin B inhibition attenuates cardiovascular pathology in mucopolysaccharidosis I mice

(2018) Esteban Alberto Gonzalez et al.   LIFE SCIENCES

Aversive and non-aversive memory impairment in the mucopolysaccharidosis II mouse model

(2017) Amanda Stapenhorst Azambuja et al.   METABOLIC BRAIN DISEASE

Identification of age-dependent motor and neuropsychological behavioural abnormalities in a mouse model of Mucopolysaccharidosis Type II

(2017) Hélène F. E. Gleitz et al.   PLoS One

Oxidative and nitrative stress and pro-inflammatory cytokines in Mucopolysaccharidosis type II patients: effect of long-term enzyme replacement therapy and relation with glycosaminoglycan accumulation

(2016) Carlos Eduardo Diaz Jacques et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Glial degeneration with oxidative damage drives neuronal demise in MPSII disease

(2016) Cristina Zalfa et al.   Cell Death & Disease

Mucopolysaccharidosis type II: Identification of 30 novel mutations among Latin American patients

(2013) A.C. Brusius-Facchin et al.   MOLECULAR GENETICS AND METABOLISM

Evidence of a progressive motor dysfunction in Mucopolysaccharidosis type I mice

(2012) Guilherme Baldo et al.   BEHAVIOURAL BRAIN RESEARCH

A practical guide to evaluating colocalization in biological microscopy

(2011) Kenneth W. Dunn et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Autophagy Controls IL-1β Secretion by Targeting Pro-IL-1β for Degradation

(2011) James Harris et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Inflammasomes

(2010) Kate Schroder et al.   CELL

The inflammasomes: mechanisms of activation and function

(2010) Eicke Latz   CURRENT OPINION IN IMMUNOLOGY

Abnormal production of macrophage inflammatory protein-1α by microglial cell lines derived from neonatal brains of Sandhoff disease model mice

(2009) Eri Kawashita et al.   JOURNAL OF NEUROCHEMISTRY

Involvement of the Toll-like receptor 4 pathway and use of TNF-  antagonists for treatment of the mucopolysaccharidoses

(2009) C. M. Simonaro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Innate and adaptive immune activation in the brain of MPS IIIB mouse model

(2008) Julianne DiRosario et al.   JOURNAL OF NEUROSCIENCE RESEARCH