Article
Medicine, General & Internal
Yen-Fu Cheng, Sudha Xirasagar, Chin-Shyan Chen, Dau-Ming Niu, Herng-Ching Lin
Summary: This study examines the associations between Fabry disease and hearing-related manifestations using a nationwide population-based dataset. It found that Fabry disease is significantly associated with certain auditory manifestations, including hearing loss, sudden deafness, and tinnitus.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Otorhinolaryngology
Tzahi Yamin, Yahav Oron, Ophir Handzel, Rani Abu Eta, Nidal Muhanna, Omer J. Ungar
Summary: This study aimed to investigate the association between neurovascular conflict (NVC) of the 8th cranial nerve (CN8) and unilateral sudden sensorineural hearing loss (SSNHL). A systematic literature search was conducted and a total of 941 publications were identified. The results showed that the prevalence of NVC was not significantly different between SSNHL affected ears and controls.
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
(2023)
Article
Clinical Neurology
Kengo Yamamoto, Takaomi Kurioka, Motofumi Ohki, Hajime Sano, Taku Yamashita
Summary: This study investigated the effect of repetitive systemic corticosteroid treatment on idiopathic sudden sensorineural hearing loss (ISSHL). The results show that repetitive systemic corticosteroid administration may have a supplementary role in hearing improvement, and early sufficient corticosteroid treatment leads to good hearing outcomes.
FRONTIERS IN NEUROLOGY
(2023)
Article
Neurosciences
Jin-Chao Hua, Xiao-Min Xu, Zhen-Gui Xu, Jin-Jing Xu, Jing-Hua Hu, Yuan Xue, Yuanqing Wu
Summary: This study investigated the topological properties of the brain connectome in sudden sensorineural hearing loss (SNHL) patients with tinnitus and its relationship with cognitive deficits. The findings suggest that SNHL patients show altered global and nodal characteristics in the brain network connectivity, which are associated with cognitive abilities and the duration of SNHL.
FRONTIERS IN NEUROSCIENCE
(2022)
Article
Otorhinolaryngology
Kimberly Luu, Amber D. Shaffer, David H. Chi
Summary: A survey was conducted to assess the practice patterns of pediatric otolaryngologists in managing children with SSNHL. Results showed that most physicians treat SSNHL with systemic steroids, but there are significant variations in other diagnostic and treatment methods.
AMERICAN JOURNAL OF OTOLARYNGOLOGY
(2023)
Article
Otorhinolaryngology
Bang-Yan Zhang, Yi-Ho Young
Summary: The study revealed that there was no significant difference in the treatment outcome of sudden sensorineural hearing loss between geriatric patients aged over 65 and non-geriatric patients aged 55-64, indicating that the aging process may not affect the treatment outcome of SD.
AMERICAN JOURNAL OF OTOLARYNGOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Reyhaneh Abgoon, Printha Wijesinghe, Cathie Garnis, Desmond A. Nunez
Summary: Sudden sensorineural hearing loss (SSNHL) is an acquired idiopathic hearing loss. This study aimed to determine if the differential expression of miRNAs persists in SSNHL patients within 1 month of hearing loss onset compared to patients 3-12 months after hearing loss onset. The study found no significant difference in miRNA expression levels, hearing recovery status, and initial and final affected ear PTA audiometric thresholds between the two groups.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Clinical Neurology
Yupeng Liu, Wenjin Wu, Shuna Li, Qing Zhang, Jingchun He, Maoli Duan, Jun Yang
Summary: The clinical characteristics and prognosis of sudden sensorineural hearing loss (SSNHL) in patients with single-sided deafness (SSD) are not well-documented. This study aimed to investigate the clinical features and treatment outcomes of SSNHL in SSD patients. The results showed that the prognosis of SSNHL in SSD patients is unsatisfactory, with SSNHL accounting for the maximum proportion of causes of SSD in this group of patients. SSD patients with SSNHL in the contralateral ear had less hearing improvement after treatment compared to SSD patients with other causes.
FRONTIERS IN NEUROLOGY
(2023)
Article
Public, Environmental & Occupational Health
Pei-Xun Zhong, I-Hsun Li, Jui-Hu Shih, Chin-Bin Yeh, Kuan-Wei Chiang, Li-Ting Kao
Summary: The use of antidepressants, regardless of class, has been found to increase the risk of sudden sensorineural hearing loss. Patients taking a higher number of classes of antidepressants are at a higher risk of developing SSNHL compared to those taking a lower number of classes.
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
(2021)
Review
Medicine, General & Internal
So Young Jeon, Dae Woong Kang, Sang Hoon Kim, Jae Yong Byun, Seung Geun Yeo
Summary: Recurrent ISSNHL patients have lower recovery rates compared to the first episode, and ear fullness symptoms and early treatment onset are associated with recovery after recurrent episodes.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Clinical Neurology
Ji Hyuk Han, SeungMin Kwak, Jeonggum Lee, Yujin Lee, Dachan Kim, Seong Hoon Bae
Summary: In this study, we evaluated the long-term prognosis and risk factors associated with tinnitus and aural fullness in patients with sudden sensorineural hearing loss. The persistence of tinnitus was significantly affected by hearing recovery after treatment, while aural fullness was not associated with hearing recovery.
OTOLOGY & NEUROTOLOGY
(2023)
Article
Medicine, General & Internal
Erum Naz, Ghulam Saqulain, Nazia Mumtaz, Muhammad Naveed Babur
Summary: This study analyzed the prevalence and characteristics of sudden sensorineural hearing loss, revealing that it is more common in males and in the age group of 15-25 years. It is mainly characterized by severe to profound degree of hearing loss, downward sloping audiogram, and is not associated with vertigo or tinnitus.
PAKISTAN JOURNAL OF MEDICAL SCIENCES
(2021)
Article
Psychology, Multidisciplinary
Wenping Xiong, Qinglei Dai, Yingjun Wang, Zhiqiang Hou, Kunpeng Lu, Xiao Sun, Fujia Duan, Haibo Wang, Daogong Zhang, Mingming Wang
Summary: This study analyzed the hearing improvement and prognosis factors of idiopathic sudden sensorineural hearing loss (ISSNHL) in different ages with initial total hearing loss. The results showed that the treatment outcomes were poor, but the 18-30 years group had better recovery than the other age groups.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Clinical Neurology
Weiming Hao, Lei Ye, Huiqian Yu, Huawei Li
Summary: This study aimed to evaluate the prognosis of vestibular function in patients with idiopathic sudden sensorineural hearing loss (ISSNHL) and vertigo. The study found that restoration of peripheral vestibular sensory input and central vestibular compensation can occur during the course of ISSNHL with vertigo. However, the recovery rate is better for the semicircular canals than for the otolith organs, and incomplete and in-process restoration of vestibular dysfunction may perturb and delay the establishment of central compensation for balance.
JOURNAL OF NEUROLOGY
(2023)
Article
Clinical Neurology
Linor Klein, Ophir Handzel, Shahaf Shilo, Yahav Oron, Rani Abu Eta, Nidal Muhanna, Omer J. Ungar
Summary: This study aims to establish a treatment cutoff for unilateral idiopathic sudden sensorineural hearing loss (ISSNHL) as an otologic emergency and determine the optimal outcome based on treatment initiation. The results show that initiating treatment within the first three days after the event leads to the best recovery outcome compared to starting treatment on or after the fourth day. Treatment initiation within the first seven or 14 days also significantly improves the chances of recovery compared to longer delays. Therefore, unilateral ISSNHL should be considered a medical emergency, and early treatment is crucial for optimal outcomes.
OTOLOGY & NEUROTOLOGY
(2023)
Article
Otorhinolaryngology
Joshua W. Wood, Blakely Thornton, C. Scott Brown, Jennifer D. McLevy, Jerome W. Thompson
INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY
(2015)
Article
Otorhinolaryngology
J. Wood, J. Ver Halen, S. Samant, N. Florendo
JOURNAL OF LARYNGOLOGY AND OTOLOGY
(2015)
Article
Otorhinolaryngology
Caleb D. Wilson, Kenneth Kennedy, Joshua W. Wood, T. K. Susheel Kumar, Rose Mary S. Stocks, Rebecca E. Thompson, Jerome W. Thompson
OTOLARYNGOLOGY-HEAD AND NECK SURGERY
(2016)
Article
Otorhinolaryngology
Bobby D. Kim, Seokchun Lim, Josh Wood, Sandeep Samant, Jon P. Ver Halen, John Y. S. Kim
ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY
(2015)
Article
Otorhinolaryngology
Jai Bikhchandani, Joshua Wood, Alan T. Richards, Russell B. Smith
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
(2014)
Letter
Surgery
Joshua Wood, Jon Ver Halen, Sandeep Samant
JOURNAL OF RECONSTRUCTIVE MICROSURGERY
(2014)
Article
Otorhinolaryngology
James B. Tansey, John Hamblin, Madhu Mamidala, Jerome Thompson, Jennifer Mclevy, Joshua Wood, Anthony Sheyn
ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY
(2020)
Article
Otorhinolaryngology
Andrew J. Maroda, Kimberly K. Coca, Jennifer D. McLevy-Bazzanella, Joshua W. Wood, Erica C. Grissom, Anthony M. Sheyn
OTOLARYNGOLOGIC CLINICS OF NORTH AMERICA
(2020)
Article
Otorhinolaryngology
Mohammad Al-Alawneh, Ladd Caballero, Elijah DeBroux, Michael J. Herr, Amy Claire Petro, Jerome Thompson, Jennifer McLevy, Joshua Wood, Madhu Mamidala, Anthony Sheyn
Summary: This study found that approximately half of the 130 patients experienced significant improvement in swallowing function after undergoing injection laryngoplasty for laryngeal clefts. Patients who were older and had more severe aspiration and penetration issues were more likely to benefit from the treatment.
ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY
(2021)
Article
Otorhinolaryngology
Kaci DeJarnette, Robert M. Frederick, Atia J. Harris, Ahsan Bashir, Joshua Wood, Anthony Sheyn
Summary: This study aimed to determine the predictive value of the VOTE score in pediatric OSA postoperative outcomes. Results showed a weakly positive correlation between VOTE score and postoperative AHI, as well as a relationship between improved postoperative AHI and postoperative O2 nadir. The study suggested that a larger sample size may be needed to validate the validity of VOTE, or a different scoring system may be required for pediatric OSA.
INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY
(2022)
Article
Otorhinolaryngology
Timothy Fan, Robert Frederick, Ahmad Abualsoud, Anthony Sheyn, Jennifer McLevy-Bazzanella, Jerome Thompson, Cem Akkus, Joshua Wood
Summary: This study retrospectively investigated the efficacy and safety of botulinum toxin injections for sialorrhea in patients under the age of three. The study found that pediatric sialorrhea was commonly associated with congenital and/or neurologic comorbidities and disproportionately impacted medically underserved black patients. Four-gland BTX injections were associated with a significant decrease in hospitalization, anticholinergic usage, and additional surgeries for sialorrhea management.
INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY
(2022)
Article
Surgery
Vikrum Thimmappa, Aaron Smith, Joshua Wood, Courtney B. Shires, Sarah Langsdon, Merry Sebelik
Article
Clinical Neurology
Joshua Wood, Jaron Densky, John Boughter, Merry Sebelik, Courtney Shires
JOURNAL OF NEUROLOGICAL SURGERY REPORTS
(2018)
Meeting Abstract
Critical Care Medicine
E. M. Newman, J. W. Wood, J. D. McLevy, J. W. Thompson, R. E. Joyner, D. C. Stokes, B. K. Haberman
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2014)