A novel patient-derived organoids-based xenografts model for preclinical drug response testing in patients with colorectal liver metastases

Cancer statistics, 2019

(2019) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Diagnostic performance of contrast-enhanced ultrasound and magnetic resonance imaging for detecting colorectal liver metastases: A systematic review and meta-analysis

(2019) Luni Zhang et al.   DIGESTIVE AND LIVER DISEASE

Epithelial NOTCH Signaling Rewires the Tumor Microenvironment of Colorectal Cancer to Drive Poor-Prognosis Subtypes and Metastasis

(2019) Rene Jackstadt et al.   CANCER CELL

An interventional image‐guided microdevice implantation and retrieval method for in‐vivo drug response assessment

(2019) Sharath K. Bhagavatula et al.   MEDICAL PHYSICS

Current and Future Horizons of Patient-Derived Xenograft Models in Colorectal Cancer Translational Research

(2019) Inoue et al.   Cancers

Patient-derived organoids can predict response to chemotherapy in metastatic colorectal cancer patients

(2019) Salo N. Ooft et al.   Science Translational Medicine

Clinical Practice Use of Liquid Biopsy to Identify RAS/BRAF Mutations in Patients with Metastatic Colorectal Cancer (mCRC): A Single Institution Experience

(2019) Vitiello et al.   Cancers

Using patient-derived xenograft models of colorectal liver metastases to predict chemosensitivity

(2018) Kai M. Brown et al.   JOURNAL OF SURGICAL RESEARCH

A surgical orthotopic organoid transplantation approach in mice to visualize and study colorectal cancer progression

(2018) Arianna Fumagalli et al.   Nature Protocols

The path to metastatic mouse models of colorectal cancer

(2018) Gabriele Romano et al.   ONCOGENE

Modeling Wnt signaling by CRISPR-Cas9 genome editing recapitulates neoplasia in human Barrett epithelial organoids

(2018) Xi Liu et al.   CANCER LETTERS

PRSS8 suppresses colorectal carcinogenesis and metastasis

(2018) Yonghua Bao et al.   ONCOGENE

Low tumor purity is associated with poor prognosis, heavy mutation burden, and intense immune phenotype in colon cancer

(2018) Yihao Mao et al.   Cancer Management and Research

Trial watch: Immunogenic cell death induction by anticancer chemotherapeutics

(2017) Abhishek D. Garg et al.   OncoImmunology

Model-based contextualization of in vitro toxicity data quantitatively predicts in vivo drug response in patients

(2016) Christoph Thiel et al.   ARCHIVES OF TOXICOLOGY

Endoscopy-guided orthotopic implantation of colorectal cancer cells results in metastatic colorectal cancer in mice

(2016) Dominik Bettenworth et al.   CLINICAL & EXPERIMENTAL METASTASIS

In Vivo Imaging Reveals Extracellular Vesicle-Mediated Phenocopying of Metastatic Behavior

(2015) Anoek Zomer et al.   CELL

Prospective Derivation of a Living Organoid Biobank of Colorectal Cancer Patients

(2015) Marc van de Wetering et al.   CELL

Modeling colorectal cancer using CRISPR-Cas9–mediated engineering of human intestinal organoids

(2015) Mami Matano et al.   NATURE MEDICINE

Discovery and saturation analysis of cancer genes across 21 tumour types

(2014) Michael S. Lawrence et al.   NATURE

‘Druggable’ alterations detected by Ion Torrent in metastatic colorectal cancer patients

(2014) WEIJIA FANG et al.   Oncology Letters

Development of a Colon Cancer GEMM-Derived Orthotopic Transplant Model for Drug Discovery and Validation

(2013) E. S. Martin et al.   CLINICAL CANCER RESEARCH

A Personalized Preclinical Model to Evaluate the Metastatic Potential of Patient-Derived Colon Cancer Initiating Cells

(2013) I. Puig et al.   CLINICAL CANCER RESEARCH

Fluorescently labeled chimeric anti-CEA antibody improves detection and resection of human colon cancer in a patient-derived orthotopic xenograft (PDOX) nude mouse model

(2013) Cristina A. Metildi et al.   JOURNAL OF SURGICAL ONCOLOGY

Landscape of genomic alterations in cervical carcinomas

(2013) Akinyemi I. Ojesina et al.   NATURE

Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples

(2013) Kristian Cibulskis et al.   NATURE BIOTECHNOLOGY

Targeted Sequencing of Cancer-Related Genes in Colorectal Cancer Using Next-Generation Sequencing

(2013) Sae-Won Han et al.   PLoS One

Dependency of Colorectal Cancer on a TGF-β-Driven Program in Stromal Cells for Metastasis Initiation

(2012) Alexandre Calon et al.   CANCER CELL

Mapping the Hallmarks of Lung Adenocarcinoma with Massively Parallel Sequencing

(2012) Marcin Imielinski et al.   CELL

Intestinal Tumorigenesis Initiated by Dedifferentiation and Acquisition of Stem-Cell-like Properties

(2012) Sarah Schwitalla et al.   CELL

Comprehensive molecular characterization of human colon and rectal cancer

(2012)   NATURE

Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium

(2011) Toshiro Sato et al.   GASTROENTEROLOGY

A framework for variation discovery and genotyping using next-generation DNA sequencing data

(2011) Mark A DePristo et al.   NATURE GENETICS

GISTIC2.0 facilitates sensitive and confident localization of the targets of focal somatic copy-number alteration in human cancers

(2011) Craig H Mermel et al.   GENOME BIOLOGY

A scalable, fully automated process for construction of sequence-ready human exome targeted capture libraries

(2011) Sheila Fisher et al.   GENOME BIOLOGY

High-resolution mapping of copy-number alterations with massively parallel sequencing

(2008) Derek Y Chiang et al.   NATURE METHODS