Rapid Polysorbate 80 Degradation by Liver Carboxylesterase in a Monoclonal Antibody Formulated Drug Substance at Early Stage Development

Title
Rapid Polysorbate 80 Degradation by Liver Carboxylesterase in a Monoclonal Antibody Formulated Drug Substance at Early Stage Development
Authors
Keywords
Antibody, Antibody drugs, Hydrolysis, Liquid chromatography-mass spectrometry (LC-MS), Proteomic
Journal
JOURNAL OF PHARMACEUTICAL SCIENCES
Volume -, Issue -, Pages -
Publisher
Elsevier BV
Online
2020-07-25
DOI
10.1016/j.xphs.2020.07.018

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