Article
Oncology
Cecelia MacFarling Meure, Belinda Steer, Judi Porter
Summary: The relationship between nutritional intake and clinical outcomes in hospitalised adult oncology patients remains unclear. This study found no significant relationship between nutritional intake and clinical outcomes. However, patients at risk of malnutrition had longer length of stay.
Review
Nutrition & Dietetics
Aitana Martin-Cantero, Esmee M. Reijnierse, Benjamin M. T. Gill, Andrea B. Maier
Summary: Nutritional interventions are effective in improving muscle mass in older adults, with amino acids, creatine, beta-hydroxy-beta-methylbutyrate, and protein with amino acids supplementation showing significant improvements. However, there is high variability in dose, duration, frequency, timing, and adherence among studies, making it challenging to establish an optimum intervention profile.
Article
Oncology
L. Bargetzi, C. Brack, J. Herrmann, A. Bargetzi, L. Hersberger, M. Bargetzi, N. Kaegi-Braun, P. Tribolet, F. Gomes, C. Hoess, V Pavlicek, S. Bilz, S. Sigrist, M. Brandle, C. Henzen, R. Thomann, J. Rutishauser, D. Aujesky, N. Rodondi, J. Donze, A. Laviano, Z. Stanga, B. Mueller, P. Schuetz
Summary: The study demonstrates that individualized nutritional support can reduce the risk of mortality and improve functional and quality of life outcomes for cancer patients with nutritional risk. These data further support the inclusion of nutritional care in cancer management guidelines.
ANNALS OF ONCOLOGY
(2021)
Review
Nutrition & Dietetics
Olivia Di Vincenzo, Maurizio Marra, Ada Di Gregorio, Fabrizio Pasanisi, Luca Scalfi
Summary: PhA is decreased in sarcopenic subjects and the prevalence of sarcopenia is higher in subjects with low PhA. PhA and sarcopenia are independent predictors of survival in cancer patients and geriatric hospitalized patients.
CLINICAL NUTRITION
(2021)
Article
Medicine, General & Internal
Seong-Jung Kim, In Ae Chun, Ju-Yeon Cho, Jun Hyung Lee, Jun Lee, Young-Dae Kim, Chan-Guk Park
Summary: This retrospective study investigated the safety and efficacy of omega-3 fatty acid-enriched parenteral nutrition in patients with acute variceal bleeding. The results showed that this nutritional approach significantly reduced the length of hospital stay.
Review
Nutrition & Dietetics
Haotian Wu, Ping'an Ding, Jiaxiang Wu, Peigang Yang, Yuan Tian, Qun Zhao
Summary: Sarcopenia refers to the age-related loss of muscle mass and function, which can be caused by various factors. Phase angle (PhA), measured through bioelectrical impedance analysis, has shown promising potential as a marker for sarcopenia in the future.
FRONTIERS IN NUTRITION
(2022)
Article
Nutrition & Dietetics
Iasmin M. Sousa, Ana Paula T. Fayh, Julia Lima, Maria Cristina Gonzalez, Carla M. Prado, Flavia M. Silva
Summary: Calf circumference (CC) is important for predicting adverse outcomes, but its accuracy is influenced by adiposity. BMI-adjusted CC has been proposed as a solution, but its predictive validity is unknown. This study evaluates the predictive validity of BMI-adjusted CC in hospital settings.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2023)
Article
Nutrition & Dietetics
Francisco Jose Sanchez-Torralvo, Nuria Porras, Ignacio Ruiz-Garcia, Cristina Maldonado-Araque, Maria Garcia-Olivares, Maria Victoria Giron, Montserrat Gonzalo-Marin, Casilda Olveira, Gabriel Olveira
Summary: This study assessed the usefulness of muscle ultrasonography in patients with cystic fibrosis and compared it with other body composition techniques. The results showed that muscle ultrasound measurements correlated adequately with body composition, muscle function, and respiratory parameters, as well as nutritional status.
Review
Nutrition & Dietetics
Oscar Barnes, Rebekah L. Wilson, Paola Gonzalo-Encabo, Dong-Woo Kang, Cami N. Christopher, Thomas Bentley, Christina M. Dieli-Conwright
Summary: Advanced and metastatic cancers significantly alter body composition, leading to physical dysfunction and poor prognosis. Little is known about the effects of exercise and nutritional interventions in patients with advanced or metastatic cancer, and further research is needed.
Article
Anesthesiology
Austin L. Du, Dennis J. Danforth, Ruth S. Waterman, Rodney A. Gabriel
Summary: This retrospective study aimed to investigate the association between recipient BMI and length of stay and mortality after liver transplant. The results showed that overweight and class 1 obesity were associated with decreased length of stay and mortality, while underweight and class 3 obesity were associated with prolonged length of stay.
ANESTHESIA AND ANALGESIA
(2022)
Article
Nutrition & Dietetics
Arabella Fischer, Cecilia Veraar, Isabella Worf, Silvia Tarantino, Noemi Kiss, Christian Schuh, Michael Hiesmayr
Summary: ICU patients face nutritional risks and a previous ICU stay may affect nutritional support upon transfer to the ward. This study found that patients with a previous ICU stay were more likely to receive enteral nutrition, parenteral nutrition, or oral nutritional supplements compared to those without an ICU stay. These findings suggest the importance of improving nutritional support for patients upon transfer to the ward, regardless of their previous ICU experience.
Review
Oncology
Maria Cristina Mele, Emanuele Rinninella, Marco Cintoni, Gabriele Pulcini, Agnese Di Donato, Futura Grassi, Ilaria Trestini, Carmelo Pozzo, Giampaolo Tortora, Antonio Gasbarrini, Emilio Bria
Summary: Lung cancer patients commonly experience malnutrition, a problem often underestimated in clinical settings. The role of nutritional interventions in these patients is not strongly proven, necessitating further research for confirmation.
CLINICAL LUNG CANCER
(2021)
Article
Oncology
Isabel M. Vegas-Aguilar, Patricia Guirado-Pelaez, Rocio Fernandez-Jimenez, Hatim Boughanem, Francisco J. Tinahones, Jose Manuel Garcia-Almeida
Summary: This study found that phase angle measured by BIA was a good diagnostic tool for detecting cancer complications in females and the risk of sarcopenia in males among colorectal cancer patients. These sex bias differences are relevant to understanding the nutritional status of CRC patients and their personalized nutritional treatment.
Article
Nutrition & Dietetics
Katja Uhlmann, Fabienne Schaller, Undine Lehmann
Summary: The application of muscle parameters in daily practice of nutritional care by dietitians in Switzerland is lacking, with low frequency of use. Lack of knowledge, practical experience, and equipment are the most common barriers for usage. Strengthening the application, along with providing practical training and education, could promote the use of muscle parameters.
Review
Nutrition & Dietetics
Desiree Victoria-Montesinos, Ana Maria Garcia-Munoz, Julia Navarro-Marroco, Carmen Lucas-Abellan, Maria Teresa Mercader-Ros, Ana Serrano-Martinez, Oriol Abellan-Aynes, Pablo Barcina-Perez, Pilar Hernandez-Sanchez
Summary: Malnutrition is a significant factor affecting the progression and mortality of cancer patients. This study aimed to analyze the relationship between different nutritional strategies, phase angle, and handgrip strength in cancer patients and their impact on other nutritional status indicators. The systematic review of randomized clinical trials showed that different nutritional strategies led to significant increases in phase angle and handgrip strength, suggesting their potential use in nutritional and functional assessment of patients.
Article
Radiology, Nuclear Medicine & Medical Imaging
Glen Lo, Angela Jacques, Jan E. Dickinson
Summary: This study aimed to review the MRI appearances of the placenta in low-risk pregnancies. A total of 83 pregnancies were included in the analysis. The results demonstrated that placental thickness, T2 heterogeneity, and T2 dark bands varied with gestational age.
JOURNAL OF MEDICAL IMAGING AND RADIATION ONCOLOGY
(2023)
Article
Anesthesiology
Alexander J. T. Wood, Rashmi Rauniyar, Angela Jacques, Robert N. Palmer, Bradley Wibrow, Matthew H. Anstey
Summary: Vasopressor dependence is a common problem in critical illness recovery, and midodrine is often used off-label to expedite weaning. However, a case-control study showed that midodrine did not accelerate the weaning from vasopressor infusions in patients who had already received prolonged courses of these infusions.
ANAESTHESIA AND INTENSIVE CARE
(2023)
Article
Emergency Medicine
Kwok M. Ho, Priya Patel, Jenny Chamberlain, Sana Nasim, Frederick B. Rogers
Summary: This study investigates the long-term outcomes of using vena cava filters to prevent symptomatic pulmonary embolism. The results show that long-term complications are rare and the cost of using filters is acceptable under certain conditions.
EUROPEAN JOURNAL OF TRAUMA AND EMERGENCY SURGERY
(2023)
Article
Emergency Medicine
Melinda Williamson, Annette Barton, Deborah Edwards, Claire Morrisby, Angela Jacques, Kristie J. Harper
Summary: The study aimed to assess the concordance between ED treatment for older adults who fall in Australia and falls prevention and management clinical guidelines. A retrospective audit of medical records revealed that assessment of cognition, medication review, and falls risk screening were commonly completed, while gait evaluation and vision review were less commonly documented. Compliance with guideline care recommendations was more likely among older patients with higher comorbidity levels, who required care assistance and received treatment from a multidisciplinary team in an observation ward.
AUSTRALASIAN EMERGENCY CARE
(2023)
Article
Medicine, General & Internal
Ailbhe C. McAlister, Kwok M. Ho
Summary: This study aimed to validate a prediction equation embedded in a smartphone application to guide dosing of Prothrombinex-VF in critically ill patients. The results showed that the app was reasonably accurate at predicting normalisation of elevated INRs after administration of Prothrombinex-VF, especially among patients without liver disease. The app's dosing recommendations were similar to or possibly better than preexisting warfarin reversal guidelines in over 85% of the situations analysed.
INTERNAL MEDICINE JOURNAL
(2023)
Article
Rehabilitation
Jessica Nolan, Angela Jacques, Erin Godecke, Hiroaki Abe, Suzanne Babyar, Jeannine Bergmann, Melissa Birnbaum, Shenhao Dai, Cynthia Danells, Taiza G. S. Edwards, Marialuisa Gandolfi, Klaus Jahn, Ryan Koter, Avril Mansfield, Junji Nakamura, Vicky Pardo, Dominic Perennou, Celine Piscicelli, David Punt, Devra Romick-Sheldon, Wim Saeys, Nicola Smania, Nathalie Vaes, Abigail L. Whitt, Barbara Singer
Summary: This study aimed to provide consensus-based clinical practice recommendations for managing post-stroke lateropulsion using an international expert panel. After four rounds of surveys, a total of 119 recommendations for rehabilitation approaches and considerations were achieved. These recommendations can guide interventions for post-stroke lateropulsion.
CLINICAL REHABILITATION
(2023)
Article
Neuroimaging
Arosha S. Dissanayake, Emalee Burrows, Kwok M. Ho, Timothy J. Phillips, Stephen Honeybul, Graeme J. Hankey
Summary: In a retrospective analysis of patients with aneurysmal subarachnoid hemorrhage (aSAH) treated with ultra-early intervention, the World Federation of Neurosurgical Societies (WFNS) grade was found to be superior to three published models for predicting re-bleeding.
JOURNAL OF NEUROINTERVENTIONAL SURGERY
(2023)
Article
Multidisciplinary Sciences
Jeffrey R. Cooley, Per Kjaer, Tue S. Jensen, Angela Jacques, Jean Theroux, Jeffrey J. Hebert
Summary: This study explores the associations between lumbar multifidus muscle quality and clinical outcomes relating to low back pain. The results indicate that higher lumbar multifidus muscle quality is associated with lower levels of low back pain-related disability and leg pain intensity, suggesting that muscle quality may play a role in the etiology of lumbar spine disorders.
Letter
Biochemistry & Molecular Biology
Kwok M. Ho
Summary: The study by Kenny et al. is highly significant as it suggests a dichotomized association between ergothioneine concentrations and preeclampsia, with a high ergothioneine level over the 90th percentile being protective against preeclampsia. Further analysis using univariable and multivariable analyses confirmed the non-linear association between ergothioneine concentrations and preeclampsia, and also identified body mass index as significantly associated with an increased risk of preeclampsia.
BIOSCIENCE REPORTS
(2023)
Article
Anesthesiology
Tomas. B. Corcoran, Catherine Martin, Edmond O'Loughlin, Kwok Ho, Matthew Chan, Andrew Forbes, Kate Leslie, Paul Myles
Summary: This study found that administering dexamethasone intraoperatively can help reduce pain levels after surgery and does not increase the occurrence of neuropathic features.
BRITISH JOURNAL OF ANAESTHESIA
(2023)
Article
Cardiac & Cardiovascular Systems
Kwok M. Ho
Summary: Biological age was found to be predictive of unplanned ICU readmission during the same hospitalization. Patients with a higher biological age compared to their chronological age were more likely to have unplanned ICU readmissions.
Article
Medicine, General & Internal
Kwok M. Ho, David J. Morgan, Mason Johnstone, Cyrus Edibam
Summary: Biological age is more accurate than chronological age in determining chronic health outcomes. This study found that biological age, assessed on ICU admission, can predict hospital mortality better than chronological age. Being phenotypically older than one's chronological age was associated with an increased risk of mortality in a dose-related fashion in the critically ill.
INTERNAL AND EMERGENCY MEDICINE
(2023)
Article
Medicine, General & Internal
Janes Alfitian, Bernhard Riedel, Hilmy Ismail, Kwok M. Ho, Sophia Xie, Philipp Zimmer, Tobias Kammerer, Duminda N. Wijeysundera, Robert Schier, METS Study Investigators
Summary: This study found that sex-specific thresholds of peak VO2 in preoperative cardiopulmonary exercise testing can better predict postoperative complications than non-sex-specific thresholds.
Article
Public, Environmental & Occupational Health
Chiara Naseri, Janet Beilby, Sharmila Vaz, Angela Jacques, Dan Xu, Luke Garswood, Hilary O'Connell, Anne-Marie Hill
Summary: This study evaluated the effectiveness of a wellness program delivered from a community hub to address the wellness needs of older adults at risk of social isolation and declining physical activity. The findings showed that the program helped older adults increase their exercise duration and prioritize social connections.
PROGRESS IN COMMUNITY HEALTH PARTNERSHIPS-RESEARCH EDUCATION AND ACTION
(2023)
Article
Medicine, General & Internal
Liying Dai, Tashi Dorje, Jan Gootjes, Amit Shah, Lawrence Dembo, Jamie Rankin, Graham Hillis, Suzanne Robinson, John J. Atherton, Angela Jacques, Christopher M. Reid, Andrew Maiorana
Summary: This study aims to evaluate the effectiveness of a multifaceted intervention to support adherence to heart failure management guidelines in primary care. A randomised controlled trial will be conducted with 200 participants, assessing the prescription of five guideline-recommended treatments and various secondary outcomes. The results will be disseminated through peer-reviewed publications and conferences.