Zonisamide promotes survival of human‐induced pluripotent stem cell‐derived dopaminergic neurons in the striatum of female rats

Human iPS cell-derived dopaminergic neurons function in a primate Parkinson’s disease model

(2017) Tetsuhiro Kikuchi et al.   NATURE

Zonisamide inhibits monoamine oxidase and enhances motor performance and social activity

(2017) Maiko T. Uemura et al.   NEUROSCIENCE RESEARCH

Extensive graft-derived dopaminergic innervation is maintained 24 years after transplantation in the degenerating parkinsonian brain

(2016) Wen Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

X-linked severe combined immunodeficiency (X-SCID) rats for xeno-transplantation and behavioral evaluation

(2015) Bumpei Samata et al.   JOURNAL OF NEUROSCIENCE METHODS

Cell-based therapies for Parkinson disease—past insights and future potential

(2015) Roger A. Barker et al.   Nature Reviews Neurology

Structural basis for LAR-RPTP/Slitrk complex-mediated synaptic adhesion

(2014) Ji Won Um et al.   Nature Communications

Isolation of Human Induced Pluripotent Stem Cell-Derived Dopaminergic Progenitors by Cell Sorting for Successful Transplantation

(2014) Daisuke Doi et al.   Stem Cell Reports

Slitrk gene duplication and expression in the developing zebrafish nervous system

(2013) Jennifer Round et al.   DEVELOPMENTAL DYNAMICS

SLITRK6 mutations cause myopia and deafness in humans and mice

(2013) Mustafa Tekin et al.   JOURNAL OF CLINICAL INVESTIGATION

Protective Effects of Zonisamide Against Rotenone-Induced Neurotoxicity

(2013) Salvatore Condello et al.   NEUROCHEMICAL RESEARCH

LAR-RPTPs: synaptic adhesion molecules that shape synapse development

(2013) Ji Won Um et al.   TRENDS IN CELL BIOLOGY

Long-term Clinical Outcome of Fetal Cell Transplantation for Parkinson Disease

(2013) Zinovia Kefalopoulou et al.   JAMA Neurology

Zonisamide up-regulated the mRNAs encoding astrocytic anti-oxidative and neurotrophic factors

(2012) ME Choudhury et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Striatal Dopamine Release Is Triggered by Synchronized Activity in Cholinergic Interneurons

(2012) Sarah Threlfell et al.   NEURON

Zonisamide Attenuates MPTP Neurotoxicity in Marmosets

(2010) Mohammed Emamussalehin Choudhury et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Zonisamide reduces cell death in SH-SY5Y cells via an anti-apoptotic effect and by upregulating MnSOD

(2010) Sumihiro Kawajiri et al.   NEUROSCIENCE LETTERS

Generation of Knockout Rats with X-Linked Severe Combined Immunodeficiency (X-SCID) Using Zinc-Finger Nucleases

(2010) Tomoji Mashimo et al.   PLoS One

Neuroprotective effects of zonisamide target astrocyte

(2009) Masato Asanuma et al.   ANNALS OF NEUROLOGY

Differential expression of slitrk family members in the mouse nervous system

(2009) François Beaubien et al.   DEVELOPMENTAL DYNAMICS

Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling

(2009) Stuart M Chambers et al.   NATURE BIOTECHNOLOGY

Disorganized Innervation and Neuronal Loss in the Inner Ear of Slitrk6-Deficient Mice

(2009) Kei-ichi Katayama et al.   PLoS One