Immune Suppression of Glia Maturation Factor Reverses Behavioral Impairment, Attenuates Amyloid Plaque Pathology and Neuroinflammation in an Alzheimer’s Disease Mouse Model

Neuron-Derived Estrogen Regulates Synaptic Plasticity and Memory

(2019) Yujiao Lu et al.   JOURNAL OF NEUROSCIENCE

Glia Maturation Factor Dependent Inhibition of Mitochondrial PGC-1α Triggers Oxidative Stress-Mediated Apoptosis in N27 Rat Dopaminergic Neuronal Cells

(2018) Govindhasamy Pushpavathi Selvakumar et al.   MOLECULAR NEUROBIOLOGY

Co-Localization of Glia Maturation Factor with NLRP3 Inflammasome and Autophagosome Markers in Human Alzheimer’s Disease Brain

(2017) Mohammad Ejaz Ahmed et al.   JOURNAL OF ALZHEIMERS DISEASE

Co-Expression of Glia Maturation Factor and Apolipoprotein E4 in Alzheimer’s Disease Brain

(2017) Ramasamy Thangavel et al.   JOURNAL OF ALZHEIMERS DISEASE

Low-level laser therapy for beta amyloid toxicity in rat hippocampus

(2017) Yujiao Lu et al.   NEUROBIOLOGY OF AGING

Glia Maturation Factor and Mitochondrial Uncoupling Proteins 2 and 4 Expression in the Temporal Cortex of Alzheimer’s Disease Brain

(2017) Ramasamy Thangavel et al.   Frontiers in Aging Neuroscience

Beneficial Effects of a CaMKIIα Inhibitor TatCN21 Peptide in Global Cerebral Ischemia

(2016) Mohammad Ejaz Ahmed et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Methylene Blue promotes cortical neurogenesis and ameliorates behavioral deficit after photothrombotic stroke in rats

(2016) Mohammad Ejaz Ahmed et al.   NEUROSCIENCE

Early Cognitive/Social Deficits and Late Motor Phenotype in Conditional Wild-Type TDP-43 Transgenic Mice

(2016) Julio A. Alfieri et al.   Frontiers in Aging Neuroscience

TREM2 deficiency eliminates TREM2+inflammatory macrophages and ameliorates pathology in Alzheimer’s disease mouse models

(2015) Taylor R. Jay et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Neuroinflammation in Alzheimer's disease

(2015) Michael T Heneka et al.   LANCET NEUROLOGY

Microglia constitute a barrier that prevents neurotoxic protofibrillar Aβ42 hotspots around plaques

(2015) Carlo Condello et al.   Nature Communications

Altered microglial response to Aβ plaques in APPPS1-21 mice heterozygous for TREM2

(2014) Jason D Ulrich et al.   Molecular Neurodegeneration

Metabotropic P2Y1 receptor signalling mediates astrocytic hyperactivity in vivo in an Alzheimer’s disease mouse model

(2014) Andrea Delekate et al.   Nature Communications

Microglia actions in Alzheimer’s disease

(2013) Stefan Prokop et al.   ACTA NEUROPATHOLOGICA

Enzyme Immunoassay and Enzyme-Linked Immunosorbent Assay

(2013) Stephanie D. Gan et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Glia Maturation Factor Induces Interleukin-33 Release from Astrocytes: Implications for Neurodegenerative Diseases

(2013) Duraisamy Kempuraj et al.   Journal of Neuroimmune Pharmacology

Neuron loss in the 5XFAD mouse model of Alzheimer’s disease correlates with intraneuronal Aβ42 accumulation and Caspase-3 activation

(2013) William A Eimer et al.   Molecular Neurodegeneration

Glia Maturation Factor Expression in Hippocampus of Human Alzheimer’s Disease

(2013) Deirdre Stolmeier et al.   NEUROCHEMICAL RESEARCH

Neuron-released oligomeric α-synuclein is an endogenous agonist of TLR2 for paracrine activation of microglia

(2013) Changyoun Kim et al.   Nature Communications

Heterogeneity of CNS myeloid cells and their roles in neurodegeneration

(2011) Marco Prinz et al.   NATURE NEUROSCIENCE

Caffeine prevents disruption of memory consolidation in the inhibitory avoidance and novel object recognition tasks by scopolamine in adult mice

(2010) Paulo Henrique Botton et al.   BEHAVIOURAL BRAIN RESEARCH

Anti-PrPC monoclonal antibody infusion as a novel treatment for cognitive deficits in an alzheimer's disease model mouse

(2010) Erika Chung et al.   BMC NEUROSCIENCE

Mortalin overexpression attenuates beta-amyloid-induced neurotoxicity in SH-SY5Y cells

(2010) Mingyue Qu et al.   BRAIN RESEARCH

Glial and neuronal control of brain blood flow

(2010) David Attwell et al.   NATURE

The Role of Microglia in Antibody-Mediated Clearance of Amyloid-Beta from the Brain

(2009) Dave Morgan   CNS & Neurological Disorders-Drug Targets

Aging-dependent changes of microglial cells and their relevance for neurodegenerative disorders

(2009) Rommy von Bernhardi et al.   JOURNAL OF NEUROCHEMISTRY

Formation and maintenance of Alzheimer's disease β-amyloid plaques in the absence of microglia

(2009) Stefan A Grathwohl et al.   NATURE NEUROSCIENCE

Inhibition of soluble TNF signaling in a mouse model of Alzheimer's disease prevents pre-plaque amyloid-associated neuropathology

(2009) Fiona E. McAlpine et al.   NEUROBIOLOGY OF DISEASE

Spaced initial stimulus familiarization enhances novelty preference in Long-Evans rats

(2008) Matthew J. Anderson et al.   BEHAVIOURAL PROCESSES

Glia maturation factor modulates β-amyloid-induced glial activation, inflammatory cytokine/chemokine production and neuronal damage

(2008) Asgar Zaheer et al.   BRAIN RESEARCH

Microglial Dysfunction and Defective  -Amyloid Clearance Pathways in Aging Alzheimer's Disease Mice

(2008) S. E. Hickman et al.   JOURNAL OF NEUROSCIENCE

Expression of interleukin-18 is increased in the brains of Alzheimer's disease patients

(2007) Johanna Ojala et al.   NEUROBIOLOGY OF AGING