Review
Clinical Neurology
Xavier Corominas-Teruel, Rosa Maria San Segundo Mozo, Montserrat Fibla Simo, Maria Teresa Colomina Fosch, Antoni Valero-Cabre
Summary: This systematic review summarizes the current state-of-the-art on the effects of tDCS for gait rehabilitation in stroke subjects. The results highlight the potential of tDCS to contribute to gait recovery following stroke, but also emphasize the urgent need to improve current stimulation strategies and subject-customized interventions.
FRONTIERS IN NEUROLOGY
(2022)
Review
Clinical Neurology
Paloma Cristina Alves de Oliveira, Thiago Anderson Brito de Araujo, Daniel Gomes da Silva Machado, Abner Cardoso Rodrigues, Marom Bikson, Suellen Marinho Andrade, Alexandre Hideki Okano, Hougelle Simplicio, Rodrigo Pegado, Edgard Morya
Summary: There was no significant short-term effect of tDCS alone on motor function, balance, gait, dyskinesias, or motor fluctuations in Parkinson's disease, regardless of brain area or the number of stimulated targets.
FRONTIERS IN NEUROLOGY
(2022)
Review
Clinical Neurology
B. Gonzalez-Rodriguez, N. Serradell-Ribe, R. Viejo-Sobera, J. P. Romero-Munoz, Elena M. Marron
Summary: This systematic review evaluated the effectiveness of transcranial direct current stimulation (tDCS) in the rehabilitation of hemispatial neglect after stroke. The findings indicate that tDCS can effectively improve neglect recovery, particularly when combined with other interventions. However, due to the limited number of studies and certain design risks, categorical conclusions cannot be drawn at this time. Further research is needed to determine the advantages of tDCS in stroke patients.
JOURNAL OF NEUROLOGY
(2022)
Review
Neurosciences
Sara Simula, Maeva Daoud, Giulio Ruffini, Maria Chiara Biagi, Christian-G Benar, Pascal Benquet, Fabrice Wendling, Fabrice Bartolomei
Summary: Transcranial electrical current stimulation (tES) has been proposed as a non-invasive therapy for pharmacoresistant epilepsy. This systematic review summarizes the clinical and fundamental effects of tES in epilepsy patients. The review shows that both direct current (tDCS) and alternating current (tACS) stimulation are safe and clinically relevant techniques for epilepsy. Further research is needed to understand the specific effects of tES on epileptic brain activity and to optimize stimulation parameters for personalized therapy.
FRONTIERS IN NEUROSCIENCE
(2022)
Review
Medicine, General & Internal
Martin Blay, Ondine Adam, Remy Bation, Filipe Galvao, Jerome Brunelin, Marine Mondino
Summary: This study aimed to investigate the effects of non-invasive brain stimulation (NIBS) on clinical and cognitive insight in patients with schizophrenia. Despite the lack of high-quality large randomized controlled trials, the available findings provide preliminary evidence that NIBS can improve clinical insight in patients with schizophrenia.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Substance Abuse
Julia P. Imperatore, Daniel M. McCalley, Jeffrey J. Borckardt, Kathleen T. Brady, Colleen A. Hanlon
Summary: For chronic pain patients with opiate misuse issues, transcranial magnetic stimulation may be more effective in reducing pain interference and opiate dependence. The study found that stimulation of the motor cortex showed more significant effects in reducing pain interference and urge to use opiates compared to stimulation of the dorsolateral prefrontal cortex.
DRUG AND ALCOHOL DEPENDENCE
(2021)
Review
Clinical Neurology
G. Darmani, T. O. Bergmann, K. Butts Pauly, C. F. Caskey, L. de Lecea, A. Fomenko, E. Fouragnan, W. Legon, K. R. Murphy, T. Nandi, M. A. Phipps, G. Pinton, H. Ramezanpour, J. Sallet, S. N. Yaakub, S. S. Yoo, R. Chen
Summary: Transcranial ultrasound stimulation (TUS) has the potential to alter neural circuits non-invasively in both animals and humans. Unlike other non-invasive brain stimulation methods, TUS can focus on both cortical and deep brain targets with unprecedented spatial resolution. The neuromodulatory effects of TUS are derived from the interaction of ultrasound waves with neuronal membranes, resulting in changes in excitability and firing rate. After years of research, TUS is now being applied in human studies and can be assessed using non-invasive brain mapping techniques. This review provides a comprehensive overview of the principles, mechanisms, effects, and potential applications of TUS.
CLINICAL NEUROPHYSIOLOGY
(2022)
Article
Clinical Neurology
Emilie Cardon, Laure Jacquemin, Hanne Vermeersch, Iris Joossen, Julie Moyaert, Griet Mertens, Olivier M. Vanderveken, Marc J. W. Lammers, Paul van de Heyning, Vincent Van Rompaey, Annick Gilles
Summary: In this study, the effects of transcranial direct current stimulation (tDCS) on chronic subjective tinnitus were investigated. The results showed that dual-site sequential high-definition tDCS did not alleviate tinnitus severity. However, Tinnitus Functional Index scores decreased more significantly in males and subjects with baseline symptoms of anxiety.
Review
Nutrition & Dietetics
James Chmiel, Anna Gladka, Jerzy Leszek
Summary: Transcranial direct current stimulation (tDCS), a non-invasive brain neuromodulation technique, has shown potential in treating anorexia nervosa (AN). Studies have demonstrated that tDCS stimulation of the left dorsolateral prefrontal cortex (DLPFC) can improve AN clinical symptoms, alter eating behavior, body weight, food intake, and reduce depression symptoms.
Review
Engineering, Biomedical
Natalia Comino-Suarez, Juan C. Moreno, Julio Gomez-Soriano, Alvaro Megia-Garcia, Diego Serrano-Munoz, Julian Taylor, Monica Alcobendas-Maestro, Angel Gil-Agudo, Antonio J. del-Ama, Juan Avendano-Coy
Summary: The systematic review found that the combination of tDCS with RT did not improve upper limb function, strength, spasticity, functional independence, or velocity of movement after stroke. However, tDCS may enhance the effects of RT alone for lower limb function.
JOURNAL OF NEUROENGINEERING AND REHABILITATION
(2021)
Article
Neurosciences
Samuel Montero-Hernandez, Luca Pollonini, Lindsey Park, Geraldine Martorella, Hongyu Miao, Kenneth B. Mathis, Hyochol Ahn
Summary: This study used fNIRS technology to investigate the effects of tDCS treatment on functional connectivity in the brains of older adults with knee OA. The results showed that tDCS intervention significantly modulated pain-related connectivity and reduced functional connections during nociception in specific brain regions. This is the first study to examine the effects of tDCS on pain-related connectivity using fNIRS.
Review
Medicine, General & Internal
Andres Pino-Esteban, Alvaro Megia-Garcia, David Martin-Caro Alvarez, Hector Beltran-Alacreu, Juan Avendano-Coy, Julio Gomez-Soriano, Diego Serrano-Munoz
Summary: Transcranial direct current stimulation (tDCS) is a non-invasive, well-tolerated, and safe technique that can affect brain excitability, particularly in individuals over the age of 60. Studies have shown that anodal tDCS applied over the motor cortex may be effective in improving balance and posture control in healthy older adults, but further high-quality randomized controlled trials are needed to determine the most effective protocols and potential benefits for this population.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Anesthesiology
Nitza Segal, Dorit Pud, Hagai Amir, Motti Ratmansky, Pora Kuperman, Liat Honigman, Roi Treister
Summary: Combining mirror therapy with tDCS resulted in a strong and long-lasting analgesic effect for patients with phantom pain, significantly reducing pain intensity and outperforming the effects of mirror therapy alone in the long term. These findings may aid in understanding the underlying mechanisms of phantom pain.
Article
Clinical Neurology
Xiaoyun Li, Junjie Yao, Wenyun Zhang, Shengxiong Chen, Weiwei Peng
Summary: This study aimed to assess the robustness of tDCS effects on experimental pain perception among healthy populations. The results showed a significant tDCS effect on attenuating pain intensity ratings to suprathreshold noxious stimuli, while effects on pain threshold and tolerance were not significant. Moderator analysis suggested that stimulation parameters and experimental pain modality moderated the effectiveness of tDCS in reducing pain intensity ratings.
CLINICAL NEUROPHYSIOLOGY
(2021)
Review
Neurosciences
Tian-Tian Chang, Yu-Hao Chang, Shu-Hao Du, Pei-Jie Chen, Xue-Qiang Wang
Summary: This article summarizes the effectiveness and limitations of NIBS techniques in the management of chronic low back pain (CLBP). It suggests that NIBS may be effective for treating CLBP, but there are limitations in current research that require further investigation.
FRONTIERS IN MOLECULAR NEUROSCIENCE
(2022)
Review
Health Care Sciences & Services
Marco Cascella, Federica Monaco, Davide Nocerino, Elisabetta Chine, Roberta Carpenedo, Paola Picerno, Laura Migliaccio, Angela Armignacco, Giulia Franceschini, Sergio Coluccia, Piergiacomo Di Gennaro, Maura C. Tracey, Cira A. Forte, Mariangela Tafuri, Anna Crispo, Francesco Cutugno, Alessandro Vittori, Silvia Natoli, Arturo Cuomo
Summary: The study conducted a bibliometric network analysis on the use of ROOs for BTcP treatment, revealing trends in published articles, distribution in journals, and main research topics. Most articles focused on the efficacy of ROOs, while abuse and misuse issues were not sufficiently addressed. Additionally, the semantic network analysis showed connections between breakthrough cancer pain, opioids, and cancers.
JOURNAL OF PAIN AND SYMPTOM MANAGEMENT
(2022)
Article
Rehabilitation
Mohammad Etoom, Kamal N. Aldaher, Abrar AlAbed Abdelhaq, Anoud Alawneh, Alia A. Alghwiri
Summary: This study investigated the perception of physiotherapy students towards the quality and satisfaction of distance learning (DL) during the COVID-19 pandemic. The results showed that while most students rated the quality of DL as good, their satisfaction levels were low. Factors such as instructor support, personal relevance, previous DL experience, and student status were identified as potential predictors of DL satisfaction.
PHYSIOTHERAPY THEORY AND PRACTICE
(2023)
Article
Rehabilitation
Salameh Aldajah, Mohammad Etoom, Sunitha Bhagavathi Mysore, Anoud Alawneh, Hikmat Hadoush, Muhammed Al Jarrah, Auwal Abdullahi
Summary: This study assessed the implementation of evidence-based physiotherapy practice (EBPTP) among physiotherapists in Jordan and identified barriers to its implementation in clinical practice. The findings revealed a clear gap in the implementation of EBPTP, which was primarily influenced by educational factors and work facilities.
PHYSIOTHERAPY THEORY AND PRACTICE
(2022)
Article
Clinical Neurology
Mohammad Al-Wardat, Christian Geroin, Tommaso Schirinzi, Mohammad Etoom, Michele Tinazzi, Antonio Pisani, Silvia Natoli
Summary: Axial postural abnormalities and pain are significant factors affecting the quality of life in Parkinson's disease patients. This study aimed to assess the characteristics of pain and other non-motor symptoms in PD patients with Pisa syndrome and camptocormia. The results showed that PD patients with Pisa syndrome or camptocormia experience more musculoskeletal, chronic, and fluctuation pain compared to PD patients without axial postural abnormalities, suggesting different etiologies of pain and potential differences in treatment approaches.
JOURNAL OF NEURAL TRANSMISSION
(2023)
Review
Environmental Sciences
Silvia Natoli, Alessandro Vittori, Marco Cascella, Massimo Innamorato, Gabriele Finco, Antonino Giarratano, Franco Marinangeli, Arturo Cuomo
Summary: The article summarizes the current situation of chronic pain management in Italy and emphasizes the importance of providing appropriate pain care to patients. It calls for more attention and multidisciplinary treatment for chronic pain patients.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2023)
Editorial Material
Clinical Neurology
Christian Geroin, Carlo Alberto Artusi, Jorik Nonnekes, Camila Aquino, Divyani L. Garg, Marian Dale, Darbe Schlosser, Yijie Lai, Mohammad Al-Wardat, Mehri Salari, Robin Wolke, Valery Tsinda Labou, Gabriele Imbalzano, Serena Camozzi, Marcelo R. Merello, Bastiaan Bloem, Tamine Capato, Ruth Djaldetti, Karen Doherty, Alfonso Fasano, Houyam Tibar, Leonardo G. Lopiano, Nils Margraf, Caroline Moreau, Yoshikazu Ugawa, Roongroj Bhidayasiri, Michele Tinazzi
MOVEMENT DISORDERS
(2023)
Article
Clinical Neurology
Felice Occhigrossi, Roberta Carpenedo, Matteo Luigi Giuseppe Leoni, Giustino Varrassi, Elisabetta Chine, Marco Cascella
Summary: A modified Delphi strategy was used to obtain recommendations for the management of percutaneous radiofrequency treatment of lumbar facet joint syndrome due to poor quality literature. A comprehensive literature search was conducted, and a semi-structured questionnaire was developed. The need for standardized protocols to address this clinical problem and fill gaps in scientific evidence was emphasized.
Article
Clinical Neurology
Mohammad Al-Wardat, Piergiorgio Grillo, Tommaso Schirinzi, Chiara Pavese, Chiara Salimei, Antonio Pisani, Silvia Natoli
Summary: Parkinson's Disease patients with constipation experience more severe pain symptoms compared to those without constipation, indicating a possible interplay between these two symptoms that needs further investigation.
JOURNAL OF NEURAL TRANSMISSION
(2023)
Article
Health Care Sciences & Services
Mohammad Al-Wardat, Mohammad Etoom, Francesco Lena, Leonardo Pellicciari, Francesco D'Amone, Oyene Kossi, Fabrizio Brindisino, Auwal Abdullahi
Summary: This study investigated the knowledge and use of effective communication strategies among Italian physiotherapists. A questionnaire with 19 questions was used to collect data on their knowledge and use of these strategies. The results showed that only 35.8% of the respondents were aware of communication strategies related to physiotherapy, and their exposure to these strategies occurred during their degree program. The study highlights the need for improvements in the training and education of physiotherapists in Italy, particularly in the area of communication strategies.
Review
Clinical Neurology
Carlo Alberto Artusi, Christian Geroin, Jorik Nonnekes, Camila Aquino, Divyani Garg, Marian L. Dale, Darbe Schlosser, Yijie Lai, Mohammad Al-Wardat, Mehri Salari, Robin Wolke, Valery Tsinda Labou, Gabriele Imbalzano, Serena Camozzi, Marcelo Merello, Bastiaan R. Bloem, Tamine Capato, Ruth Djaldetti, Karen Doherty, Alfonso Fasano, Houyam Tibar, Leonardo Lopiano, Nils G. Margraf, Caroline Moreau, Yoshikazu Ugawa, Roongroj Bhidayasiri, Michele Tinazzi
Summary: Axial postural abnormalities are common in patients with Parkinson's disease and atypical parkinsonism, and have a significant impact on the patients' quality of life. However, there is limited understanding of the pathophysiology and clinical predictors of these symptoms, highlighting the need for further research in this area.
MOVEMENT DISORDERS CLINICAL PRACTICE
(2023)
Article
Medicine, General & Internal
Manal M. Al Battat, Mohammad Etoom, Alia A. Alghwiri
Summary: The study aimed to investigate the relationship between sleep quality and shoulder disorders in people after a stroke, as well as its association with stroke outcomes. The results showed that sleep quality was more closely related to the non-motor outcomes of stroke, such as pain, cognitive fatigue, and mental status. Considering sleep quality is essential in upper extremity rehabilitation and care processes.
MEDICINA-LITHUANIA
(2023)
Article
Clinical Neurology
Christian Geroin, Carlo Alberto Artusi, Jorik Nonnekes, Camila Aquino, Divyani Garg, Marian L. Dale, Darbe Schlosser, Yijie Lai, Mohammad Al-Wardat, Mehri Salari, Robin Wolke, Valery Tsinda Labou, Gabriele Imbalzano, Serena Camozzi, Marcelo Merello, Bastiaan R. Bloem, Tamine Capato, Ruth Djaldetti, Karen Doherty, Alfonso Fasano, Houyam Tibar, Leonardo Lopiano, Nils G. Margraf, Caroline Moreau, Yoshikazu Ugawa, Roongroj Bhidayasiri, Michele Tinazzi
MOVEMENT DISORDERS
(2023)
Article
Health Care Sciences & Services
Mohammad Etoom, Alhadi M. M. Jahan, Alia Alghwiri, Francesco Lena, Nicola Modugno
Summary: Management of ataxia involves rehabilitation, symptomatic management, and functional improvement. Content analysis of recommended ataxia rating scales can help clinicians select the most appropriate scale for assessing ataxic symptoms and their impact on function.
Article
Health Care Sciences & Services
Marco Cascella, Alessandro Vittori, Emiliano Petrucci, Franco Marinangeli, Antonino Giarratano, Cristina Cacciagrano, Emiliano Simone Tizi, Luca Miceli, Silvia Natoli, Arturo Cuomo
Summary: The strengths of cancer pain management in Italy include careful opioid prescriptions, strategies for treating neuropathic pain, patient/provider partnerships, and breakthrough cancer pain management. However, there are weaknesses that need to be addressed, such as poor adherence to guidelines, inadequate attention to patient quality of life, insufficient use of minimally invasive techniques, lack of teamwork approaches, inappropriate timing of pain specialist engagement, and underutilization of telemedicine.
