Discovery and anti-cancer evaluation of two novel non-ATP-competitive FGFR1 inhibitors in non-small-cell lung cancer

Discovery and identification of new non-ATP competitive FGFR1 inhibitors with therapeutic potential on non-small-cell lung cancer

(2013) Yi Wang et al.   CANCER LETTERS

Small molecule inhibition of fibroblast growth factor receptors in cancer

(2013) Guang Liang et al.   CYTOKINE & GROWTH FACTOR REVIEWS

MicroRNA-198 Inhibits Proliferation and Induces Apoptosis of Lung Cancer Cells Via Targeting FGFR1

(2013) Jun Yang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Fibroblast growth factor receptor 1 (FGFR1) copy number is an independent prognostic factor in non-small cell lung cancer

(2013) Thang N. Tran et al.   LUNG CANCER

High rate of FGFR1 amplifications in brain metastases of squamous and non-squamous lung cancer

(2013) Matthias Preusser et al.   LUNG CANCER

Activation of the FGF2-FGFR1 Autocrine Pathway: A Novel Mechanism of Acquired Resistance to Gefitinib in NSCLC

(2013) Hideki Terai et al.   MOLECULAR CANCER RESEARCH

Strategies for the Selective Regulation of Kinases with Allosteric Modulators: Exploiting Exclusive Structural Features

(2012) Zhizhou Fang et al.   ACS Chemical Biology

Translating the Therapeutic Potential of AZD4547 in FGFR1-Amplified Non-Small Cell Lung Cancer through the Use of Patient-Derived Tumor Xenograft Models

(2012) J. Zhang et al.   CLINICAL CANCER RESEARCH

FGFR1 Amplification in Squamous Cell Carcinoma of The Lung

(2012) Rebecca S. Heist et al.   Journal of Thoracic Oncology

Anticancer molecules targeting fibroblast growth factor receptors

(2012) Guang Liang et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

FGFR1 expression and gene copy numbers in human lung cancer

(2012) Lukas H. Kohler et al.   VIRCHOWS ARCHIV

A Novel Mode of Protein Kinase Inhibition Exploiting Hydrophobic Motifs of Autoinhibited Kinases

(2011) Sudharshan Eathiraj et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evaluation and Discovery of Novel Synthetic Chalcone Derivatives as Anti-Inflammatory Agents

(2011) Jianzhang Wu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Inhibitor-Sensitive FGFR1 Amplification in Human Non-Small Cell Lung Cancer

(2011) Amit Dutt et al.   PLoS One

NF449 Is a Novel Inhibitor of Fibroblast Growth Factor Receptor 3 (FGFR3) Signaling Active in Chondrocytes and Multiple Myeloma Cells

(2010) Pavel Krejci et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tyrosine-kinase inhibitors—new standard for NSCLC therapy

(2010) Nagahiro Saijo   Nature Reviews Clinical Oncology

Resistance to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Non-Small Cell Lung Cancer

(2009) P. S. Hammerman et al.   CLINICAL CANCER RESEARCH

Epidermal Growth Factor Receptor Inhibitors and Antiangiogenic Agents for the Treatment of Non-Small Cell Lung Cancer

(2009) L. Horn et al.   CLINICAL CANCER RESEARCH

The fibroblast growth factor receptor signaling pathway as a mediator of intrinsic resistance to EGFR-specific tyrosine kinase inhibitors in non-small cell lung cancer

(2009) Scott A. Kono et al.   DRUG RESISTANCE UPDATES

Novel mutant-selective EGFR kinase inhibitors against EGFR T790M

(2009) Wenjun Zhou et al.   NATURE

Nordihydroguaiaretic Acid Inhibits an Activated Fibroblast Growth Factor Receptor 3 Mutant and Blocks Downstream Signaling in Multiple Myeloma Cells

(2008) A. N. Meyer et al.   CANCER RESEARCH