4.6 Article

Repeated COVID-19 relapse during post- discharge surveillance with viral shedding lasting for 67 days in a recovered patient infected with SARS-CoV-2

Journal

JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION
Volume 54, Issue 1, Pages 101-104

Publisher

ELSEVIER TAIWAN
DOI: 10.1016/j.jmii.2020.07.017

Keywords

Coronavirus disease 2019; Prognosis; Recovered patients; SARS-CoV-2 re-positive; Viral shedding

Funding

  1. Hangzhou research project of 2019coronavirus disease [20202013A01]

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This case study revealed a prolonged viral shedding time of 67 days, with COVID-19 relapse attributed to inconsistent chest radiography and SARS-CoV-2-RNA detection post-discharge. Lopinavirinterferon a2b boosted ribavirin with subsequent lopinavir boosted budesonide may be an effective treatment for viral clearance.
A case who revealed the longest duration of viral shedding (67 days) in current reports, presented complicated characteristic on the relapse of COVID-19 due to the inconsistent performance of chest radiography and SARS-CoV-2-RNA detection after discharge. Lopinavirinterferon a2b boosted ribavirin following with lopinavir boosted budesonide might be a potent treatment for viral clearance. Copyright (c) 2020, Taiwan Society of Microbiology. Published by Elsevier Taiwan LLC. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/bync-nd/4.0/).

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