Andrographolide enhanced radiosensitivity by downregulating glycolysis via the inhibition of the PI3K-Akt-mTOR signaling pathway in HCT116 colorectal cancer cells

Cancer statistics, 2019

(2019) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Advances and challenges in developing andrographolide and its analogues as cancer therapeutic agents

(2019) Hon Liong Soo et al.   DRUG DISCOVERY TODAY

Andrographolide: A natural product template for the generation of structurally and biologically diverse diterpenes

(2019) Sai Giridhar Sarma Kandanur et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

RBBP6 increases radioresistance and serves as a therapeutic target for preoperative radiotherapy in colorectal cancer

(2018) Chao Xiao et al.   CANCER SCIENCE

Silencing the Girdin gene enhances radio-sensitivity of hepatocellular carcinoma via suppression of glycolytic metabolism

(2017) Li Yu et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Enzyme targeting strategies for prevention and treatment of cancer: Implications for cancer therapy

(2017) Mohammad Hassan Baig et al.   SEMINARS IN CANCER BIOLOGY

Increased reactive oxygen species levels cause ER stress and cytotoxicity in andrographolide treated colon cancer cells

(2017) Aditi Banerjee et al.   Oncotarget

CCR6 Is a Predicting Biomarker of Radiosensitivity and Potential Target of Radiosensitization in Rectal Cancer

(2017) Hui Chang et al.   Cancer Research and Treatment

The Emerging Hallmarks of Cancer Metabolism

(2016) Natalya N. Pavlova et al.   Cell Metabolism

Warburg effect, hexokinase-II, and radioresistance of laryngeal carcinoma

(2016) Jiang-Tao Zhong et al.   Oncotarget

Andrographolide impedes cancer stemness and enhances radio-sensitivity in oral carcinomas via miR-218 activation

(2016) Po-Yu Yang et al.   Oncotarget

Targeting pyruvate kinase M2 contributes to radiosensitivity of non-small cell lung cancer cells in vitro and in vivo

(2015) Mao-Bin Meng et al.   CANCER LETTERS

Targeting PI3K/Akt/mTOR signaling pathway in the treatment of prostate cancer radioresistance

(2015) Lei Chang et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Targeting EGFR-PI3K-AKT-mTOR signaling enhances radiosensitivity in head and neck squamous cell carcinoma

(2015) Dominik Horn et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Cancer metabolism and the Warburg effect: the role of HIF-1 and PI3K

(2015) Rupert Courtnay et al.   MOLECULAR BIOLOGY REPORTS

Andrographolide radiosensitizes human ovarian cancer SKOV3 xenografts due to an enhanced apoptosis and autophagy

(2015) Chao Zhang et al.   TUMOR BIOLOGY

Radiation-induced microRNA-622 causes radioresistance in colorectal cancer cells by down-regulating Rb

(2015) Wenhui Ma et al.   Oncotarget

Small molecule-driven mitophagy-mediated NLRP3 inflammasome inhibition is responsible for the prevention of colitis-associated cancer

(2014) Wenjie Guo et al.   Autophagy

Icariin Enhances Radiosensitivity of Colorectal Cancer Cells by Suppressing NF-κB Activity

(2014) Yi Zhang et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Andrographolide radiosensitizes human esophageal cancer cell line ECA109 to radiationin vitro

(2014) Z.-M. Wang et al.   DISEASES OF THE ESOPHAGUS

Andrographolide reduces proliferation and migration of lens epithelial cells by modulating PI3K/Akt pathway

(2014) Forum Kayastha et al.   EXPERIMENTAL EYE RESEARCH

A Fresh View of Glycolysis and Glucokinase Regulation: History and Current Status

(2014) Sigurd Lenzen   JOURNAL OF BIOLOGICAL CHEMISTRY

Synthetic Genistein Glycosides Inhibiting EGFR Phosphorylation Enhance the Effect of Radiation in HCT 116 Colon Cancer Cells

(2014) Aleksandra Gruca et al.   MOLECULES

Major Late Toxicities After Conformal Radiotherapy for Nasopharyngeal Carcinoma—Patient- and Treatment-Related Risk Factors

(2008) Anne W.M. Lee et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS