Article
Gastroenterology & Hepatology
Rosario Arena, Andrea Lisotti, Alessandro Mussetto, Alberto Merighi, Alessandro Pezzoli, Omero Triossi
Summary: Our study found that male gender, age, antithrombotic medications, and right-sided diverticular disease are independently associated with diverticular bleeding.
DIGESTIVE AND LIVER DISEASE
(2021)
Review
Gastroenterology & Hepatology
Giacomo Calini, Mohamed A. Abd El Aziz, Lucia Paolini, Solafah Abdalla, Matteo Rottoli, Giulio Mari, David W. Larson
Summary: Symptomatic Uncomplicated Diverticular Disease (SUDD) is a chronic condition characterized by local abdominal pain and bowel movement changes. It impairs quality of life and is associated with low-grade inflammation. Risk factors include age, genetic predisposition, obesity, physical inactivity, low-fiber diet, and smoking. The pathogenesis of SUDD involves fecal microbiota alterations, neuro-immune enteric interactions, and muscular system dysfunction. Treatment aims to improve symptoms and quality of life through a healthy lifestyle, probiotics, and medications like Rifaximin and Mesalazine. Surgery may be considered for patients with treatment failure and impaired quality of life. However, further studies are needed to evaluate the efficacy and safety of these interventions.
CLINICAL AND EXPERIMENTAL GASTROENTEROLOGY
(2023)
Article
Surgery
Joshua Underhill, Maria C. Mora Pinzon, Ethan Ritz, Miles Grunvald, Sarah Jochum, Adan Becerra, Anuradha Bhama, Henry Govekar, Theodore Saclarides, Dana Hayden
Summary: This study analyzed the demographic characteristics of diverticular fistula on a national level. It found that diverticular fistula is a rare diagnosis, accounting for 3.12% of hospital admissions for diverticular disease. Younger females are more likely to be affected, but only 64.9% of patients received surgical treatment.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2023)
Article
Public, Environmental & Occupational Health
Gabriella Yazbeck, Diana Malaeb, Hamid Shaaban, Abir Sarray El Dine, Souheil Hallit, Rabih Hallit
Summary: This study aimed to assess the rate of unidentified IBS among Lebanese adults and investigate the role of socio-demographic factors, anxiety, depression, insomnia, and eating attitudes on IBS diagnosis. A cross-sectional study was conducted using a self-reporting questionnaire distributed via social media. The study found that higher psychological distress and insomnia severity were significantly associated with higher odds of having possible unidentified IBS.
Review
Gastroenterology & Hepatology
David Saavedra-Perez, Yuhamy Curbelo-Pena, Jaime Sampson-Davila, Sonia Albertos, Alejandro Serrano, Luis Ibanez, Xavier Errando, Xavier Perez
Summary: The aim of this systematic review is to clarify the scientific evidence and analyze the diagnostic and therapeutic options for Symptomatic Uncomplicated Diverticular Colon Disease (SUDCD), comparing their advantages and disadvantages and proposing a diagnostic-therapeutic algorithm along with new research questions.
GASTROENTEROLOGIA Y HEPATOLOGIA
(2021)
Review
Health Care Sciences & Services
Antonio Tursi, Valerio Papa, Loris Riccardo Lopetuso, Lorenzo Maria Vetrone, Antonio Gasbarrini, Alfredo Papa
Summary: Colonoscopy is a crucial tool in the management of diverticular disease, with roles in diagnosis, differential diagnosis, prognostic evaluation, and treatment of complications.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Gastroenterology & Hepatology
Chanyang Lee, Geoffrey Menezes
Summary: Small bowel diverticulosis is a rare and usually asymptomatic condition that can lead to the formation of enteroliths and bowel obstruction. This case report presents a rare recurrence of small bowel diverticula enterolith impaction.
WORLD JOURNAL OF GASTROINTESTINAL SURGERY
(2022)
Article
Medicine, General & Internal
Christopher F. Brewer, Yayha Al Abed
Summary: A man in his 40's was admitted to the general surgery ward with multiple episodes of painless bright red rectal bleeding and clots. Urgent outpatient colonoscopy revealed a diverticulum with a wide diameter blood vessel originating from its base, which was not actively bleeding. This case is one of the first to clearly identify large caliber blood vessels emerging from a colonic diverticulum.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2021)
Article
Gastroenterology & Hepatology
Antonio Tursi, Walter Elisei, Marilisa Franceschi, Marcello Picchio, Francesco Di Mario, Giovanni Brandimarte
Summary: The prevalence of symptomatic uncomplicated diverticular disease (SUDD) in a real-life population seems to be lower than expected, with most patients with diverticulosis and abdominal symptoms likely suffering from irritable bowel syndrome (IBS)-like symptoms or other causes. SUDD and post-diverticulitis SUDD (PD-SUDD) were more common in older patients (>60 years), while IBS-like symptoms were more common in younger patients.
EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
(2021)
Article
Gastroenterology & Hepatology
Scott MacDonald, Linda MacDonald, Jon Godwin, Angus Macdonald, Michelle Thornton
Summary: Provisional research on faecal immunohistochemical test (FIT) for symptomatic colorectal patients has shown high sensitivity for CRC and SBD, with nearly 100% negative predictive value for CRC. However, using FIT as the sole referral pathway for symptomatic colorectal patients may miss a certain percentage of diseases.
COLORECTAL DISEASE
(2022)
Article
Plant Sciences
Zhaoqin Wang, Manwen Xu, Zheng Shi, Chunhui Bao, Huirong Liu, Cili Zhou, Yilu Yan, Chunye Wang, Guona Li, Wei Zhang, Anqi Gao, Huangan Wu
Summary: This study aimed to evaluate the effects of mild moxibustion (MM) for the treatment of irritable bowel syndrome with diarrhea (IBS-D) and compare them with placebo moxibustion. The findings suggest that mild moxibustion may be more effective than placebo moxibustion for the treatment of IBS-D, with effects lasting up to 12 weeks.
JOURNAL OF ETHNOPHARMACOLOGY
(2022)
Review
Gastroenterology & Hepatology
Sarvee Moosavi, Mark Pimentel, Melissa S. Wong, Ali Rezaie
Summary: Irritable bowel syndrome (IBS) is more common in women, especially those of childbearing age, but there is a lack of research and guidelines on managing IBS during pregnancy. Multidisciplinary approach emphasizing education and cautious use of safe dietary modifications and medications should be employed for pregnant women with IBS.
AMERICAN JOURNAL OF GASTROENTEROLOGY
(2021)
Article
Medicine, General & Internal
Venkata Vinod Kumar Matli, Viveksandeep Thoguluva Chandrasekar, Jason L. Campbell, Chandana Karanam, Sathya Jaganmohan
Summary: Diverticulosis is a rare bowel wall condition that can affect the small or large bowel. Jejunal diverticulosis, particularly jejunal diverticulitis, is a rare complication that can be managed conservatively with antibiotics. This case report describes a successful conservative management of adhesive jejunal diverticulitis in a 41-year-old patient, highlighting the distinctive finding of fat stranding.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2022)
Article
Gastroenterology & Hepatology
Moana Gelu-Simeon, Matthieu Schnee, Marie-Josee Lafrance, Pauline Plazy-Chabrand, Anne-Sophie Schneck, Georgette Saint-Georges, Marceline Alexis, Stephanie Delumeau, Philippe Montigny, Roger Faroux, Jerome Dimet, Eric Saillard
Summary: This study compares the anatomical presentation and severity of colonic diverticulosis in African Caribbeans and Europeans. The findings suggest that diverticulosis in African Caribbeans tends to be pancolonic and associated with more severe hemorrhage, possibly driven by genetic factors.
CANADIAN JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
(2022)
Review
Psychiatry
Shefaly Shorey, Alla Demutska, Valerie Chan, Kewin Tien Ho Siah
Summary: This study synthesized 17 qualitative studies on the experiences of adults living with IBS, highlighting the negative impacts on physical, psychological, and social aspects, and the need for future research on diverse geographical locations. Furthermore, interventions such as technology-based support, trained peer volunteers, mindfulness, and cognitive behavioural therapy are essential for supporting IBS patients. Collaboration among stakeholders is crucial for developing standardized tools and materials for accurate testing, diagnosis, assessment, treatment, and management of IBS.
JOURNAL OF PSYCHOSOMATIC RESEARCH
(2021)
Article
Multidisciplinary Sciences
Anna Andreasson, Bianka Karshikoff, Lisa Lidberg, Torbjorn Akerstedt, Martin Ingvar, Caroline Olgart Hoglund, John Axelsson, Mats Lekander
Article
Gastroenterology & Hepatology
David T. McNaughton, Anna Andreasson, Brjann Ljotsson, Alissa P. Beath, Julia M. Hush, Nicholas J. Talley, Gunnar Ljunggren, Peter T. Schmidt, Lars Agreus, Michael P. Jones
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2020)
Article
Gastroenterology & Hepatology
Hannes Hagstrom, Mats Talback, Anna Andreasson, Goran Walldius, Niklas Hammar
Article
Gastroenterology & Hepatology
Brjann Ljotsson, Michael Jones, Nicholas J. Talley, Lars Kjellstrom, Lars Agreus, Anna Andreasson
UNITED EUROPEAN GASTROENTEROLOGY JOURNAL
(2020)
Article
Gastroenterology & Hepatology
Bjarki Alexandersson, Yousef Hamad, Anna Andreasson, Carlos A. Rubio, Yugo Ando, Kyosuke Tanaka, Tamaki Ichiya, Reza Rezaie, Peter T. Schmidt
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2020)
Article
Gastroenterology & Hepatology
Hannes Hagstrom, Mats Talback, Anna Andreasson, Goran Walldius, Niklas Hammar
JOURNAL OF HEPATOLOGY
(2020)
Editorial Material
Gastroenterology & Hepatology
Nicholas J. Talley, Marjorie M. Walker, Lars Agreus, Anna Andreasson
ALIMENTARY PHARMACOLOGY & THERAPEUTICS
(2021)
Article
Pathology
Mudar Zand Irani, Nicholas J. Talley, Jukka Ronkainen, Pertti Aro, Anna Andreasson, Lars Agreus, Michael Vieth, Mike P. Jones, Marjorie M. Walker
Summary: In healthy individuals, the healthy esophageal mucosa does not contain more than three IELs per five HPF in the distal esophagus. Independent predictors of an elevated IEL count include spongiosis on histology and current smoking.
Article
Clinical Neurology
Anna Andreasson, John Axelsson, Jos A. Bosch, Leonie J. T. Balter
Summary: This study showed that long sleep duration is associated with poorer self-rated health only if combined with poor sleep quality, while good sleep quality can protect individuals with long sleep duration from poor health. Fatigue and sleep quality are potential pathways linking both short and long sleep durations with self-rated health. Different dimensions of sleep interact in their association with health, highlighting the importance of an integrative approach in future research.
Article
Gastroenterology & Hepatology
Hannes Hagstrom, Jacinth Yan, Mats Talback, Anna Andreasson, Goran Walldius, Matteo Bottai, Niklas Hammar
Summary: This study aims to improve the commonly used FIB-4 score in identifying subgroups at risk of cirrhosis by using commonly available biomarkers. The results show that the accuracy of identifying severe liver disease risk can be significantly improved by combining age and specific biomarkers with the FIB-4 score.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS
(2023)
Article
Gastroenterology & Hepatology
Bjarki T. Alexandersson, Luisa W. Hugerth, Charlotte Hedin, Anna Forsberg, Nicholas J. Talley, Lars Agreus, Ellionore Jarbrink-Sehgal, Lars Engstrand, Anna Andreasson, Peter T. Schmidt
Summary: This population-based study compared the fecal and mucosa-associated microbiota between participants with and without diverticulosis, as well as participants who later developed acute diverticulitis versus those who did not. The results showed no significant differences in microbiota composition between participants with or without diverticulosis, except for a higher abundance of the genus Comamonas in individuals who later developed diverticulitis. This suggests a limited role for the gut microbiota in the etiopathogenesis of diverticular disease.
SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY
(2023)
Article
Nutrition & Dietetics
Therese Liljebo, Stine Storsrud, Anna Andreasson
Article
Immunology
Anna Andreasson, David Mcnaughton, Alissa Beath, Karin Lodin, Rikard K. Wicksell, Mats Lekander, Michael P. Jones
BRAIN, BEHAVIOR, & IMMUNITY - HEALTH
(2020)
Article
Psychology, Clinical
Martin A. Jonsjo, Rikard K. Wicksell, Linda Holmstrom, Anna Andreasson, Gunnar L. Olsson
JOURNAL OF CONTEXTUAL BEHAVIORAL SCIENCE
(2019)
Article
Immunology
Karin Lodin, Mats Lekander, Predrag Petrovic, Gustav Nilsonne, Erik Hedman-Lagerlof, Anna Andreasson
EUROPEAN JOURNAL OF INFLAMMATION
(2019)