Considerations for Empiric Antimicrobial Therapy in Sepsis and Septic Shock in an Era of Antimicrobial Resistance

Supply Chain Delays in Antimicrobial Administration After the Initial Clinician Order and Mortality in Patients With Sepsis

(2019) Markos G. Kashiouris et al.   CRITICAL CARE MEDICINE

Diagnosis and Treatment of Adults with Community-acquired Pneumonia. An Official Clinical Practice Guideline of the American Thoracic Society and Infectious Diseases Society of America

(2019) Joshua P. Metlay et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Impact of an automated antibiotic time-out alert on the de-escalation of broad-spectrum antibiotics at a large community teaching hospital

(2019) Jenna R. Wolfe et al.   INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY

Antibiotic Order-to-Infusion Time for Patients With Septic Shock

(2019) Michael Klompas et al.   CRITICAL CARE MEDICINE

Prolonged versus short-term intravenous infusion of antipseudomonal β-lactams for patients with sepsis: a systematic review and meta-analysis of randomised trials

(2018) Konstantinos Z Vardakas et al.   LANCET INFECTIOUS DISEASES

Prehospital antibiotics in the ambulance for sepsis: a multicentre, open label, randomised trial

(2018) Nadia Alam et al.   Lancet Respiratory Medicine

Effect of Piperacillin-Tazobactam vs Meropenem on 30-Day Mortality for Patients With E coli or Klebsiella pneumoniae Bloodstream Infection and Ceftriaxone Resistance

(2018) Patrick N. A. Harris et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Comparison of SIRS, qSOFA, and NEWS for the early identification of sepsis in the Emergency Department

(2018) Omar A. Usman et al.   AMERICAN JOURNAL OF EMERGENCY MEDICINE

Empiric Antibiotic Treatment Thresholds for Serious Bacterial Infections: A Scenario-Based Survey Study

(2018) Alex M Cressman et al.   CLINICAL INFECTIOUS DISEASES

Antibiotic Thresholds for Sepsis and Septic Shock

(2018) Marin H Kollef et al.   CLINICAL INFECTIOUS DISEASES

The ideal patient profile for new beta-lactam/beta-lactamase inhibitors

(2018) Philippe Montravers et al.   CURRENT OPINION IN INFECTIOUS DISEASES

Ceftolozane-Tazobactam for the Treatment of Multidrug-Resistant Pseudomonas aeruginosa Infections: A Multicenter Study

(2018) Jason C Gallagher et al.   Open Forum Infectious Diseases

Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016

(2017) Andrew Rhodes et al.   INTENSIVE CARE MEDICINE

Should we consider faecal colonisation with extended-spectrum β-lactamase-producing Enterobacteriaceae in empirical therapy of community-onset sepsis?

(2017) Daša Stupica et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Incidence and Trends of Sepsis in US Hospitals Using Clinical vs Claims Data, 2009-2014

(2017) Chanu Rhee et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Time to Treatment and Mortality during Mandated Emergency Care for Sepsis

(2017) Christopher W. Seymour et al.   NEW ENGLAND JOURNAL OF MEDICINE

The impact of delayed biliary decompression and anti-microbial therapy in 260 patients with cholangitis-associated septic shock

(2016) C. J. Karvellas et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

A Clinical Decision Tree to Predict Whether a Bacteremic Patient Is Infected With an Extended-Spectrum β-Lactamase–Producing Organism

(2016) Katherine E. Goodman et al.   CLINICAL INFECTIOUS DISEASES

Implementing an Antibiotic Stewardship Program: Guidelines by the Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America

(2016) Tamar F. Barlam et al.   CLINICAL INFECTIOUS DISEASES

Management of Adults With Hospital-acquired and Ventilator-associated Pneumonia: 2016 Clinical Practice Guidelines by the Infectious Diseases Society of America and the American Thoracic Society

(2016) Andre C. Kalil et al.   CLINICAL INFECTIOUS DISEASES

Executive Summary: Clinical Practice Guideline for the Management of Candidiasis: 2016 Update by the Infectious Diseases Society of America

(2016) Peter G. Pappas et al.   CLINICAL INFECTIOUS DISEASES

Fecal Colonization With Extended-spectrum Beta-lactamase–ProducingEnterobacteriaceaeand Risk Factors Among Healthy Individuals: A Systematic Review and Metaanalysis

(2016) Styliani Karanika et al.   CLINICAL INFECTIOUS DISEASES

Empirical Micafungin Treatment and Survival Without Invasive Fungal Infection in Adults With ICU-Acquired Sepsis, Candida Colonization, and Multiple Organ Failure

(2016) Jean-Francois Timsit et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Implementation of Rapid Molecular Infectious Disease Diagnostics: the Role of Diagnostic and Antimicrobial Stewardship

(2016) Kevin Messacar et al.   JOURNAL OF CLINICAL MICROBIOLOGY

De-Escalation of Antibiotics Does Not Increase Mortality in Critically Ill Surgical Patients

(2016) Kristin C. Turza et al.   Surgical Infections

The global epidemiology of carbapenemase-producing Enterobacteriaceae

(2016) David van Duin et al.   Virulence

Predictive Value of Prior Colonization and Antibiotic Use for Third-Generation Cephalosporin-Resistant Enterobacteriaceae Bacteremia in Patients With Sepsis

(2015) Wouter C. Rottier et al.   CLINICAL INFECTIOUS DISEASES

A targeted real-time early warning score (TREWScore) for septic shock

(2015) Katharine E. Henry et al.   Science Translational Medicine

Fecal ESBL Escherichia coli carriage as a risk factor for bacteremia in patients with hematological malignancies

(2015) Patricia Cornejo-Juárez et al.   SUPPORTIVE CARE IN CANCER

A quality improvement project to improve early sepsis care in the emergency department

(2015) Medley O'Keefe Gatewood et al.   BMJ Quality & Safety

Executive Summary: Practice Guidelines for the Diagnosis and Management of Skin and Soft Tissue Infections: 2014 Update by the Infectious Diseases Society of America

(2014) Dennis L. Stevens et al.   CLINICAL INFECTIOUS DISEASES

Risk factors for carbapenem-resistant Klebsiella pneumoniae bloodstream infection among rectal carriers: a prospective observational multicentre study

(2014) M. Giannella et al.   CLINICAL MICROBIOLOGY AND INFECTION

Empiric Antibiotic Treatment Reduces Mortality in Severe Sepsis and Septic Shock From the First Hour

(2014) Ricard Ferrer et al.   CRITICAL CARE MEDICINE

Surgical delay is a critical determinant of survival in perforated peptic ulcer

(2013) D. L. Buck et al.   BRITISH JOURNAL OF SURGERY

Late recognition and illness severity are determinants of early death in severe septic patients

(2013) FR Machado et al.   Clinics

Trends and Significance of VRE Colonization in the ICU: A Meta-Analysis of Published Studies

(2013) Panayiotis D. Ziakas et al.   PLoS One

National prevalence of methicillin-resistant Staphylococcus aureus in inpatients at United States health care facilities, 2010

(2012) William R. Jarvis et al.   AMERICAN JOURNAL OF INFECTION CONTROL

Empiric antibiotic, mechanical ventilation, and central venous catheter duration as potential factors mediating the effect of a checklist prompting intervention on mortality: an exploratory analysis

(2012) Curtis H Weiss et al.   BMC HEALTH SERVICES RESEARCH

Asymptomatic rectal carriage of blaKPC producing carbapenem-resistant Enterobacteriaceae: who is prone to become clinically infected?

(2012) V. Schechner et al.   CLINICAL MICROBIOLOGY AND INFECTION

Frequency of Microbiologically Correct Antibiotic Therapy Increased by Infectious Disease Consultations and Microbiological Results

(2012) J. J. Kerremans et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Risk factors for developing clinical infection with carbapenem-resistant Klebsiella pneumoniae in hospital patients initially only colonized with carbapenem-resistant K pneumoniae

(2011) Abraham Borer et al.   AMERICAN JOURNAL OF INFECTION CONTROL

International Clinical Practice Guidelines for the Treatment of Acute Uncomplicated Cystitis and Pyelonephritis in Women: A 2010 Update by the Infectious Diseases Society of America and the European Society for Microbiology and Infectious Diseases

(2011) Kalpana Gupta et al.   CLINICAL INFECTIOUS DISEASES

Improving Door-to-Antibiotic Time in Severely Septic Emergency Department Patients

(2011) Eveline A. Hitti et al.   JOURNAL OF EMERGENCY MEDICINE

Etiology of Illness in Patients with Severe Sepsis Admitted to the Hospital from the Emergency Department

(2010) Alan C. Heffner et al.   CLINICAL INFECTIOUS DISEASES

Impact of time to antibiotics on survival in patients with severe sepsis or septic shock in whom early goal-directed therapy was initiated in the emergency department*

(2010) David F. Gaieski et al.   CRITICAL CARE MEDICINE

Initiation of Inappropriate Antimicrobial Therapy Results in a Fivefold Reduction of Survival in Human Septic Shock

(2009) Anand Kumar et al.   CHEST

Diagnosis and Management of Complicated Intra‐abdominal Infection in Adults and Children: Guidelines by the Surgical Infection Society and the Infectious Diseases Society of America

(2009) Joseph S. Solomkin et al.   CLINICAL INFECTIOUS DISEASES

Randomized trial of combination versus monotherapy for the empiric treatment of suspected ventilator-associated pneumonia*

(2009) Daren K. Heyland et al.   CRITICAL CARE MEDICINE

Hospital-wide impact of a standardized order set for the management of bacteremic severe sepsis*

(2009) Steven W. Thiel et al.   CRITICAL CARE MEDICINE

Role of the infectious diseases specialist consultant on the appropriateness of antimicrobial therapy prescription in an intensive care unit

(2008) Enrico Raineri et al.   AMERICAN JOURNAL OF INFECTION CONTROL