Thymoquinone (Tq) protects necroptosis induced by autophagy/mitophagy‐dependent oxidative stress in human bronchial epithelial cells exposed to cigarette smoke extract (CSE)

Thymoquinone and curcumin combination protects cisplatin-induced kidney injury, nephrotoxicity by attenuating NFκB, KIM-1 and ameliorating Nrf2/HO-1 signalling

(2020) Majed Al Fayi et al.   JOURNAL OF DRUG TARGETING

Thymoquinone attenuates phosphorylation of AKT to inhibit kidney cancer cell proliferation

(2019) Ayed Dera et al.   JOURNAL OF FOOD BIOCHEMISTRY

Rational combinations of indirubin and arylidene derivatives exhibit synergism in human non‐small cell lung carcinoma cells

(2019) Prasanna Rajagopalan et al.   JOURNAL OF FOOD BIOCHEMISTRY

Thymoquinone attenuates oxidative stress of kidney mitochondria and exerts nephroprotective effects in oxonic acid‐induced hyperuricemia rats

(2019) Ayed A. Dera et al.   BIOFACTORS

The protective effects of thymoquinone on lung damage caused by cigarette smoke

(2019) Nur Aleyna Yetkin et al.   BIOTECHNIC & HISTOCHEMISTRY

RIP1, RIP3, and MLKL Contribute to Cell Death Caused by Clostridium perfringens Enterotoxin

(2019) Archana Shrestha et al.   mBio

Cigarette smoke-induced autophagy impairment accelerates lung aging, COPD-emphysema exacerbations and pathogenesis

(2018) Neeraj Vij et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Thymoquinone alleviates the experimentally induced Alzheimer’s disease inflammation by modulation of TLRs signaling

(2018) YS Abulfadl et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Chronic cigarette smoking-induced oxidative/nitrosative stress in human erythrocytes and platelets

(2018) Pannuru Padmavathi et al.   Molecular & Cellular Toxicology

Nigella sativa fixed oil as alternative treatment in management of pain in Arthritis rheumatoid

(2018) Mohaddese Mahboubi et al.   PHYTOMEDICINE

Therapeutic potential of thymoquinone liposomes against the systemic infection of Candida albicans in diabetic mice

(2018) Masood A. Khan et al.   PLoS One

Autophagy, selective autophagy, and necroptosis in COPD

(2018) Kenji Mizumura et al.   International Journal of Chronic Obstructive Pulmonary Disease

Monitoring and Measuring Autophagy

(2017) Saori R. Yoshii et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Inflammatory Effects of Menthol vs. Non-menthol Cigarette Smoke Extract on Human Lung Epithelial Cells: A Double-Hit on TRPM8 by Reactive Oxygen Species and Menthol

(2017) An-Hsuan Lin et al.   Frontiers in Physiology

Mitochondrial fusion by pharmacological manipulation impedes somatic cell reprogramming to pluripotency: New insight into the role of mitophagy in cell stemness

(2016) Alejandro Vazquez-Martin et al.   Aging-US

Analysis of the Effects of Cigarette Smoke on Staphylococcal Virulence Phenotypes

(2015) Elisa K. McEachern et al.   INFECTION AND IMMUNITY

mTOR: a pharmacologic target for autophagy regulation

(2015) Young Chul Kim et al.   JOURNAL OF CLINICAL INVESTIGATION

Mitophagy-dependent necroptosis contributes to the pathogenesis of COPD

(2014) Kenji Mizumura et al.   JOURNAL OF CLINICAL INVESTIGATION

Cerebral ischemia-reperfusion-induced autophagy protects against neuronal injury by mitochondrial clearance

(2013) Xiangnan Zhang et al.   Autophagy

New insights into the function and regulation of mitochondrial fission

(2013) Hidenori Otera et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Attenuation of Doxorubicin-Induced Cardiotoxicity by mdivi-1: A Mitochondrial Division/Mitophagy Inhibitor

(2013) Mayel Gharanei et al.   PLoS One

Mitophagy is triggered by mild oxidative stress in a mitochondrial fission dependent manner

(2012) Magdalena Frank et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

ROS-dependent regulation of Parkin and DJ-1 localization during oxidative stress in neurons

(2012) Alvin P. Joselin et al.   HUMAN MOLECULAR GENETICS

Human Alveolar Epithelial Cell Injury Induced by Cigarette Smoke

(2011) Beata Kosmider et al.   PLoS One

Pathogenic triad in COPD: oxidative stress, protease–antiprotease imbalance, and inflammation

(2011) Bernard Fischer et al.   International Journal of Chronic Obstructive Pulmonary Disease

Induction of autophagy-dependent necroptosis is required for childhood acute lymphoblastic leukemia cells to overcome glucocorticoid resistance

(2010) Laura Bonapace et al.   JOURNAL OF CLINICAL INVESTIGATION

Termination of autophagy and reformation of lysosomes regulated by mTOR

(2010) Li Yu et al.   NATURE

Mitochondrial fusion and fission in cell life and death

(2010) Benedikt Westermann   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mechanisms of mitophagy

(2010) Richard J. Youle et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin

(2010) Derek P. Narendra et al.   PLOS BIOLOGY

The Natural History of Chronic Airflow Obstruction Revisited

(2009) Robab Kohansal et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Protective Effect of Quercetin against Gentamicin-Induced Nephrotoxicity in Rats

(2009) Ihab Talat Abdel-Raheem et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Mitochondrial dynamics-fusion, fission, movement, and mitophagy-in neurodegenerative diseases

(2009) H. Chen et al.   HUMAN MOLECULAR GENETICS

Farnesol ameliorates massive inflammation, oxidative stress and lung injury induced by intratracheal instillation of cigarette smoke extract in rats: An initial step in lung chemoprevention

(2008) Wajhul Qamar et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Egr-1 Regulates Autophagy in Cigarette Smoke-Induced Chronic Obstructive Pulmonary Disease

(2008) Zhi-Hua Chen et al.   PLoS One