D-Glucose uptake and clearance in the tauopathy Alzheimer’s disease mouse brain detected by on-resonance variable delay multiple pulse MRI

In vivo imaging of phosphocreatine with artificial neural networks

(2020) Lin Chen et al.   Nature Communications

Altered d-glucose in brain parenchyma and cerebrospinal fluid of early Alzheimer’s disease detected by dynamic glucose-enhanced MRI

(2020) Jianpan Huang et al.   Science Advances

T1ρ-based dynamic glucose-enhanced (DGEρ) MRI at 3 T: method development and early clinical experience in the human brain

(2019) Kai Herz et al.   MAGNETIC RESONANCE IN MEDICINE

Meningeal lymphatic vessels at the skull base drain cerebrospinal fluid

(2019) Ji Hoon Ahn et al.   NATURE

High‐resolution creatine mapping of mouse brain at 11.7 T using non‐steady‐state chemical exchange saturation transfer

(2019) Lin Chen et al.   NMR IN BIOMEDICINE

Forecasting the prevalence of preclinical and clinical Alzheimer's disease in the United States

(2018) Ron Brookmeyer et al.   Alzheimers & Dementia

Separating fast and slow exchange transfer and magnetization transfer using off-resonance variable-delay multiple-pulse (VDMP) MRI

(2018) Lin Chen et al.   MAGNETIC RESONANCE IN MEDICINE

Chemical exchange-sensitive spin-lock (CESL) MRI of glucose and analogs in brain tumors

(2018) Tao Jin et al.   MAGNETIC RESONANCE IN MEDICINE

Dynamic glucose enhanced MRI of the placenta in a mouse model of intrauterine inflammation

(2018) Dan Wu et al.   PLACENTA

Gadolinium-based Contrast Media, Cerebrospinal Fluid and the Glymphatic System: Possible Mechanisms for the Deposition of Gadolinium in the Brain

(2018) Toshiaki Taoka et al.   Magnetic Resonance in Medical Sciences

GlucoCEST imaging with on-resonance variable delay multiple pulse (onVDMP) MRI

(2018) Xiang Xu et al.   MAGNETIC RESONANCE IN MEDICINE

Creatine and phosphocreatine mapping of mouse skeletal muscle by a polynomial and Lorentzian line-shape fitting CEST method

(2018) Lin Chen et al.   MAGNETIC RESONANCE IN MEDICINE

Functional aspects of meningeal lymphatics in ageing and Alzheimer’s disease

(2018) Sandro Da Mesquita et al.   NATURE

Deuterium metabolic imaging (DMI) for MRI-based 3D mapping of metabolism in vivo

(2018) Henk M. De Feyter et al.   Science Advances

Possible artifacts in dynamic CEST MRI due to motion and field alterations

(2018) Moritz Zaiss et al.   JOURNAL OF MAGNETIC RESONANCE

Protein aggregation linked to Alzheimer's disease revealed by saturation transfer MRI

(2018) Lin Chen et al.   NEUROIMAGE

Chemical exchange-sensitive spin-lock MRI of glucose analog 3-O-methyl-d-glucose in normal and ischemic brain

(2017) Tao Jin et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Is Tau Imaging More Than Just Upside-Down 18 F-FDG Imaging?

(2017) Thilo van Eimeren et al.   JOURNAL OF NUCLEAR MEDICINE

Investigation of the contribution of total creatine to the CEST Z -spectrum of brain using a knockout mouse model

(2017) Lin Chen et al.   NMR IN BIOMEDICINE

T1ρ-weighted Dynamic Glucose-enhanced MR Imaging in the Human Brain

(2017) Daniel Paech et al.   RADIOLOGY

Earliest accumulation of β-amyloid occurs within the default-mode network and concurrently affects brain connectivity

(2017) Sebastian Palmqvist et al.   Nature Communications

Outflow of cerebrospinal fluid is predominantly through lymphatic vessels and is reduced in aged mice

(2017) Qiaoli Ma et al.   Nature Communications

Fast and Quantitative T1ρ-weighted Dynamic Glucose Enhanced MRI

(2017) Patrick Schuenke et al.   Scientific Reports

Adiabatically prepared spin-lock approach for T1ρ-based dynamic glucose enhanced MRI at ultrahigh fields

(2016) Patrick Schuenke et al.   MAGNETIC RESONANCE IN MEDICINE

On-resonance variable delay multipulse scheme for imaging of fast-exchanging protons and semisolid macromolecules

(2016) Jiadi Xu et al.   MAGNETIC RESONANCE IN MEDICINE

The neuritic plaque facilitates pathological conversion of tau in an Alzheimer’s disease mouse model

(2016) Tong Li et al.   Nature Communications

Scan-rescan reproducibility of parallel transmission based amide proton transfer imaging of brain tumors

(2015) Osamu Togao et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

Dynamic glucose enhanced (DGE) MRI for combined imaging of blood-brain barrier break down and increased blood volume in brain cancer

(2015) Xiang Xu et al.   MAGNETIC RESONANCE IN MEDICINE

GLUT1 reductions exacerbate Alzheimer's disease vasculo-neuronal dysfunction and degeneration

(2015) Ethan A Winkler et al.   NATURE NEUROSCIENCE

Early Detection of Cerebral Glucose Uptake Changes in the 5XFAD Mouse

(2014) I.R. Macdonald et al.   Current Alzheimer Research

Mapping Brain Glucose Uptake with Chemical Exchange-Sensitive Spin-Lock Magnetic Resonance Imaging

(2014) Tao Jin et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Natural D-glucose as a biodegradable MRI relaxation agent

(2014) Nirbhay N. Yadav et al.   MAGNETIC RESONANCE IN MEDICINE

Two Phase 3 Trials of Bapineuzumab in Mild-to-Moderate Alzheimer's Disease

(2014) Stephen Salloway et al.   NEW ENGLAND JOURNAL OF MEDICINE

InverseZ-spectrum analysis for spillover-, MT-, andT1-corrected steady-state pulsed CEST-MRI - application to pH-weighted MRI of acute stroke

(2014) Moritz Zaiss et al.   NMR IN BIOMEDICINE

Amyloid-β and Tau

(2014) George S. Bloom   JAMA Neurology

Amyloid β deposition, neurodegeneration, and cognitive decline in sporadic Alzheimer's disease: a prospective cohort study

(2013) Victor L Villemagne et al.   LANCET NEUROLOGY

In vivo imaging of glucose uptake and metabolism in tumors

(2013) Simon Walker-Samuel et al.   NATURE MEDICINE

NaturalD-glucose as a biodegradable MRI contrast agent for detecting cancer

(2012) Kannie W. Y. Chan et al.   MAGNETIC RESONANCE IN MEDICINE

Differential effect of APOE genotype on amyloid load and glucose metabolism in AD dementia

(2012) R. Ossenkoppele et al.   NEUROLOGY

A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid  

(2012) J. J. Iliff et al.   Science Translational Medicine

Posterior Cingulate Glucose Metabolism, Hippocampal Glucose Metabolism, and Hippocampal Volume in Cognitively Normal, Late-Middle-Aged Persons at 3 Levels of Genetic Risk for Alzheimer Disease

(2012) Hillary D. Protas et al.   JAMA Neurology

Animal research: Reporting in vivo experiments: The ARRIVE guidelines

(2010) Carol Kilkenny et al.   BRITISH JOURNAL OF PHARMACOLOGY

Intensity-Based Image Registration by Minimizing Residual Complexity

(2010) Andriy Myronenko et al.   IEEE TRANSACTIONS ON MEDICAL IMAGING

A simple approach for three-dimensional mapping of baseline cerebrospinal fluid volume fraction

(2010) Qin Qin   MAGNETIC RESONANCE IN MEDICINE

Spin-locking versus chemical exchange saturation transfer MRI for investigating chemical exchange process between water and labile metabolite protons

(2010) Tao Jin et al.   MAGNETIC RESONANCE IN MEDICINE

The use of PET in Alzheimer disease

(2010) Agneta Nordberg et al.   Nature Reviews Neurology

Characterization of 7- and 19-month-old Tg2576 mice using multimodal in vivo imaging: limitations as a translatable model of Alzheimer's disease

(2010) Feng Luo et al.   NEUROBIOLOGY OF AGING