IL‐17A‐producing T cells exacerbate fine particulate matter‐induced lung inflammation and fibrosis by inhibiting PI3K/Akt/mTOR‐mediated autophagy

Proteomic profile of TGF-β1 treated lung fibroblasts identifies novel markers of activated fibroblasts in the silica exposed rat lung

(2019) Mao Na et al.   EXPERIMENTAL CELL RESEARCH

Inhibition of Rac1 activity alleviates PM2.5-induced pulmonary inflammation via the AKT signaling pathway

(2019) Shuijuan Zhang et al.   TOXICOLOGY LETTERS

Integrative characterization of fine particulate matter-induced chronic obstructive pulmonary disease in mice

(2019) Qiuyue Li et al.   SCIENCE OF THE TOTAL ENVIRONMENT

GOLGA2 loss causes fibrosis with autophagy in the mouse lung and liver

(2018) Sungjin Park et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

PI3K/AKT/mTOR activation and autophagy inhibition plays a key role in increased cholesterol during IL-17A mediated inflammatory response in psoriasis

(2018) Pallavi Varshney et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Mitochondrial damage mediated by ROS incurs bronchial epithelial cell apoptosis upon ambient PM2.5 exposure

(2018) Xiaoting Jin et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

Inflammation and fibrosis

(2018) Matthias Mack   MATRIX BIOLOGY

The airway inflammation induced by nasal inoculation of PM2.5 and the treatment of bacterial lysates in rats

(2018) Yang Shen et al.   Scientific Reports

TGF-β receptors: In and beyond TGF-β signaling

(2018) Alexandra Vander Ark et al.   CELLULAR SIGNALLING

Bufei Huoxue Capsule Attenuates PM2.5-Induced Pulmonary Inflammation in Mice

(2017) Yue Jing et al.   Evidence-based Complementary and Alternative Medicine

Lysocardiolipin acyltransferase regulates TGF-β mediated lung fibroblast differentiation

(2017) Long Shuang Huang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Oral administration of Lactobacillus paracasei L9 attenuates PM2.5-induced enhancement of airway hyperresponsiveness and allergic airway response in murine model of asthma

(2017) Xifan Wang et al.   PLoS One

Interleukin-17 induces human alveolar epithelial to mesenchymal cell transition via the TGF-β1 mediated Smad2/3 and ERK1/2 activation

(2017) Ting Wang et al.   PLoS One

IL-27 inhibits the TGF-β1-induced epithelial-mesenchymal transition in alveolar epithelial cells

(2016) Zhaoxing Dong et al.   BMC CELL BIOLOGY

Respective IL-17A production by γδ T and Th17 cells and its implication in host defense against chlamydial lung infection

(2016) Hong Bai et al.   Cellular & Molecular Immunology

Short-term Effects of Outdoor Air Pollution on Lung Function among Female Non-smokers in China

(2016) Yun Zhou et al.   Scientific Reports

Effect of Fine Particulate Matter (PM2.5) on Rat Placenta Pathology and Perinatal Outcomes

(2016) Yi Liu et al.   MEDICAL SCIENCE MONITOR

Autophagy mechanisms in sputum and peripheral blood cells of patients with severe asthma: a new therapeutic target

(2015) G.-Y. Ban et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Innate cellular sources of interleukin-17A regulate macrophage accumulation in cigarette- smoke-induced lung inflammation in mice

(2015) Steven Bozinovski et al.   CLINICAL SCIENCE

The Role of Mitochondrial DNA in Mediating Alveolar Epithelial Cell Apoptosis and Pulmonary Fibrosis

(2015) Seok-Jo Kim et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Particulate matter 2.5 induces autophagy via inhibition of the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin kinase signaling pathway in human bronchial epithelial cells

(2015) TIE LIU et al.   Molecular Medicine Reports

Compromised peroxisomes in idiopathic pulmonary fibrosis, a vicious cycle inducing a higher fibrotic response via TGF-β signaling

(2015) Gani Oruqaj et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Conditioned media from mesenchymal stromal cells restore sodium transport and preserve epithelial permeability in an in vitro model of acute alveolar injury

(2014) Arnaud Goolaerts et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

IL-17 induces type V collagen overexpression and EMT via TGF-β-dependent pathways in obliterative bronchiolitis

(2012) Ragini Vittal et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Blocking IL-17A Promotes the Resolution of Pulmonary Inflammation and Fibrosis Via TGF- 1-Dependent and -Independent Mechanisms

(2011) S. Mi et al.   JOURNAL OF IMMUNOLOGY

Lung and brainstem cytokine levels are associated with breathing pattern changes in a rodent model of acute lung injury

(2011) Frank J. Jacono et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Blockade of Interleukin-17A Results in Reduced Atherosclerosis in Apolipoprotein E–Deficient Mice

(2010) Emily Smith et al.   CIRCULATION

Episodic Exposure to Fine Particulate Air Pollution Decreases Circulating Levels of Endothelial Progenitor Cells

(2010) Timothy E. O'Toole et al.   CIRCULATION RESEARCH

Interleukin-17A Is Dispensable for Myocarditis but Essential for the Progression to Dilated Cardiomyopathy

(2010) G. Christian Baldeviano et al.   CIRCULATION RESEARCH

Protective effect of sesamol on the pulmonary inflammatory response and lung injury in endotoxemic rats

(2010) Pei-Yi Chu et al.   FOOD AND CHEMICAL TOXICOLOGY

Bleomycin and IL-1β–mediated pulmonary fibrosis is IL-17A dependent

(2010) Mark S. Wilson et al.   JOURNAL OF EXPERIMENTAL MEDICINE

New Mechanisms of Pulmonary Fibrosis

(2009) Robert M. Strieter et al.   CHEST

Rapid pulmonary fibrosis induced by acute lung injury via a lipopolysaccharide three-hit regimen

(2009) Hui Li et al.   Innate Immunity

Apoptosis in lung injury and fibrosis

(2008) F. Drakopanagiotakis et al.   EUROPEAN RESPIRATORY JOURNAL