Calcitonin inhibits intervertebral disc degeneration by regulating protein kinase C

IL-10 delays the degeneration of intervertebral discs by suppressing the p38 MAPK signaling pathway

(2019) Jun Ge et al.   FREE RADICAL BIOLOGY AND MEDICINE

Low back pain: a major global challenge

(2018) Stephanie Clark et al.   LANCET

Prolactin inhibits the progression of intervertebral disc degeneration through inactivation of the NF-κB pathway in rats

(2018) Xiexing Wu et al.   Cell Death & Disease

Preclinical development of a microRNA-based therapy for intervertebral disc degeneration

(2018) Ming-liang Ji et al.   Nature Communications

Calcitonin protects chondrocytes from lipopolysaccharide-induced apoptosis and inflammatory response through MAPK/Wnt/NF-κB pathways

(2017) Lai-Bo Zhang et al.   MOLECULAR IMMUNOLOGY

Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013

(2015) Theo Vos et al.   LANCET

Calcitonin suppresses intervertebral disk degeneration and preserves lumbar vertebral bone mineral density and bone strength in ovariectomized rats

(2015) F.-m. Tian et al.   OSTEOPOROSIS INTERNATIONAL

The inhibitory effect of salmon calcitonin on intervertebral disc degeneration in an ovariectomized rat model

(2014) Yang Luo et al.   EUROPEAN SPINE JOURNAL

Injectable, high-density collagen gels for annulus fibrosus repair: Anin vitrorat tail model

(2014) Brandon Borde et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Oral salmon calcitonin protects against impaired fasting glycemia, glucose intolerance, and obesity induced by high-fat diet and ovariectomy in rats

(2013) Michael Feigh et al.   MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY

C-Fos Regulation by the MAPK and PKC Pathways in Intervertebral Disc Cells

(2013) Katsuya Yokoyama et al.   PLoS One

Annular Repair Using High-Density Collagen Gel

(2013) Peter Grunert et al.   SPINE

The role of the ERK1/2 pathway as an alternative to the aging-diminished cyclic AMP pathway in calcitonin-mediated chondrogenesis in human nucleus pulposus

(2012) Wei-Hong Chen et al.   BIOMATERIALS

Ex vivo observation of human intervertebral disc tissue and cells isolated from degenerated intervertebral discs

(2012) Gabriela Ciapetti et al.   EUROPEAN SPINE JOURNAL

The expression and role of non-canonical (PKC) signaling in nucleus pulposus cell metabolism

(2012) Fumiyuki Arai et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

The pathophysiologic role of the protein kinase Cδ pathway in the intervertebral discs of rabbits and mice: In vitro, ex vivo, and in vivo studies

(2011) Michael B. Ellman et al.   ARTHRITIS AND RHEUMATISM

Modified house-keeping gene expression in a rat tail compression loading-induced disc degeneration model

(2011) Takashi Yurube et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

The Effect of Injection Volume on Disc Degeneration in a Rat Tail Model

(2011) Hua-jie Mao et al.   SPINE

Calcitonin Enhanced Lumbar Spinal Fusion in a New Zealand Rabbit Model

(2011) Yong Liu et al.   SPINE

Cartilage tissue enhances proteoglycan retention by nucleus pulposus cells in vitro

(2010) Claudia J. Arana et al.   ARTHRITIS AND RHEUMATISM

Alendronate prevents lumbar intervertebral disc degeneration in ovariectomized rats

(2010) Zhen Li et al.   BONE

The effect of oral salmon calcitonin delivered with 5-CNAC on bone and cartilage degradation in osteoarthritic patients: a 14-day randomized study

(2009) M.A. Karsdal et al.   OSTEOARTHRITIS AND CARTILAGE

Recent advances in annular pathobiology provide insights into rim-lesion mediated intervertebral disc degeneration and potential new approaches to annular repair strategies

(2008) James Melrose et al.   EUROPEAN SPINE JOURNAL

Enhanced Type X Collagen Expression in the Extruded Nucleus Pulposus of the Chondrodystrophoid Dog

(2008) Hisanori ITOH et al.   JOURNAL OF VETERINARY MEDICAL SCIENCE

Structural Basis of Protein Kinase C Isoform Function

(2008) Susan F. Steinberg   PHYSIOLOGICAL REVIEWS

The cellular pathobiology of the degenerate intervertebral disc and discogenic back pain

(2008) A. J. Freemont   RHEUMATOLOGY