Endoplasmic reticulum stress‐induced exosomal miR‐27a‐3p promotes immune escape in breast cancer via regulating PD‐L1 expression in macrophages

Endoplasmic Reticulum Stress Promotes Liver Cancer Cells to Release Exosomal miR-23a-3p and Up-regulate PD-L1 Expression in Macrophages

(2019) Jiatao Liu et al.   HEPATOLOGY

Insluin and epithelial growth factor (EGF) promote programmed death ligand 1(PD-L1) production and transport in colon cancer stem cells

(2019) Mingshui Chen et al.   BMC CANCER

Immune induction strategies in metastatic triple-negative breast cancer to enhance the sensitivity to PD-1 blockade: the TONIC trial

(2019) Leonie Voorwerk et al.   NATURE MEDICINE

Long non-coding RNA TTN-AS1 promotes the progression of lung adenocarcinoma by regulating PTEN/PI3K/AKT signaling pathway

(2019) Jiwen Luo et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

IFN-γ-mediated inhibition of lung cancer correlates with PD-L1 expression and is regulated by PI3K-AKT signaling

(2018) Yi Gao et al.   INTERNATIONAL JOURNAL OF CANCER

Tumour-infiltrating lymphocytes and prognosis in different subtypes of breast cancer: a pooled analysis of 3771 patients treated with neoadjuvant therapy

(2018) Carsten Denkert et al.   LANCET ONCOLOGY

MAGI2 is an independent predictor of biochemical recurrence in prostate cancer

(2018) Stephanie N. David et al.   PROSTATE

Analysis of MicroRNA Signature Differentially Expressed in Exosomes from Adriamycin-resistant and Parental Human Breast Cancer Cells

(2018) Wei-xian Chen et al.   BIOSCIENCE REPORTS

CCL20 triggered by chemotherapy hinders the therapeutic efficacy of breast cancer

(2018) Weilong Chen et al.   PLOS BIOLOGY

PD-L1 on tumor cells is sufficient for immune evasion in immunogenic tumors and inhibits CD8 T cell cytotoxicity

(2017) Vikram R. Juneja et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Partial-breast radiotherapy after breast conservation surgery for patients with early breast cancer (UK IMPORT LOW trial): 5-year results from a multicentre, randomised, controlled, phase 3, non-inferiority trial

(2017) Charlotte E Coles et al.   LANCET

miR-27a-3p targeting RXRα promotes colorectal cancer progression by activating Wnt/β-catenin pathway

(2017) Jiangtao Liang et al.   Oncotarget

The miR-25-93-106b cluster regulates tumor metastasis and immune evasion via modulation of CXCL12 and PD-L1

(2017) Michele Cioffi et al.   Oncotarget

MiR-487a Promotes TGF-β1-induced EMT, the Migration and Invasion of Breast Cancer Cells by Directly Targeting MAGI2

(2016) Mengtao Ma et al.   International Journal of Biological Sciences

MicroRNAs in extracellular vesicles: potential cancer biomarkers

(2016) Takashi Kinoshita et al.   JOURNAL OF HUMAN GENETICS

miR-27a-mediated antiproliferative effects of metformin on the breast cancer cell line MCF-7

(2016) Wei Zhao et al.   ONCOLOGY REPORTS

MiR-27a-3p functions as an oncogene in gastric cancer by targeting BTG2

(2016) Lin Zhou et al.   Oncotarget

Exosomes in carcinogenesis: molecular palkis carry signals for the regulation of cancer progression and metastasis

(2016) Arvind Subramanian et al.   Journal of Cell Communication and Signaling

Breast cancer

(2015) Chris Woolston   NATURE

Regulation of exosome release from mammary epithelial and breast cancer cells – A new regulatory pathway

(2014) Andrew Riches et al.   EUROPEAN JOURNAL OF CANCER

Cell-extrinsic effects of the tumor unfolded protein response on myeloid cells and T cells

(2013) Maurizio Zanetti   Annals of the New York Academy of Sciences

MAGI2 enhances the sensitivity of BEL-7404 human hepatocellular carcinoma cells to staurosporine-induced apoptosis by increasing PTEN stability

(2013) XIN LI et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

MiR-134/487b/655 Cluster Regulates TGF- -Induced Epithelial-Mesenchymal Transition and Drug Resistance to Gefitinib by Targeting MAGI2 in Lung Adenocarcinoma Cells

(2013) K. Kitamura et al.   MOLECULAR CANCER THERAPEUTICS

MicroRNAs as mediators of viral evasion of the immune system

(2013) Bryan R Cullen   NATURE IMMUNOLOGY

PARP16 is a tail-anchored endoplasmic reticulum protein required for the PERK- and IRE1α-mediated unfolded protein response

(2012) Miri Jwa et al.   NATURE CELL BIOLOGY

Tumor progression by immune evasion in melanoma

(2010) Mohammed Kashani-Sabet   CANCER

Macrophage Diversity Enhances Tumor Progression and Metastasis

(2010) Bin-Zhi Qian et al.   CELL

MicroRNA-101-mediated Akt activation and estrogen-independent growth

(2010) M Sachdeva et al.   ONCOGENE