Corilagin suppresses RANKL‐induced osteoclastogenesis and inhibits oestrogen deficiency‐induced bone loss via the NF‐κB and PI3K/AKT signalling pathways

TRAIL inhibits RANK signaling and suppresses osteoclast activation via inhibiting lipid raft assembly and TRAF6 recruitment

(2019) Hsiu-Jung Liao et al.   Cell Death & Disease

Corilagin Interferes With Toll-Like Receptor 3-Mediated Immune Response in Herpes Simplex Encephalitis

(2019) Lu-Jun Li et al.   Frontiers in Molecular Neuroscience

Activation of ROS/MAPKs/NF-κB/NLRP3 and inhibition of efferocytosis in osteoclast-mediated diabetic osteoporosis

(2019) Yanan An et al.   FASEB JOURNAL

Association Between Drug Treatments for Patients With Osteoporosis and Overall Mortality Rates

(2019) Steven R. Cummings et al.   JAMA Internal Medicine

From Osteoclast Differentiation to Osteonecrosis of the Jaw: Molecular and Clinical Insights

(2019) Anesi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

l -tetrahydropalmatine suppresses osteoclastogenesis in vivo and in vitro via blocking RANK-TRAF6 interactions and inhibiting NF-κB and MAPK pathways

(2019) Xin Zhi et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Targeting Macrophages: Friends or Foes in Disease?

(2019) Juan A. Ardura et al.   Frontiers in Pharmacology

Synergistic combination treatment to break cross talk between cancer cells and bone cells to inhibit progression of bone metastasis

(2019) Sivakumar Vijayaraghavalu et al.   BIOMATERIALS

Blocking glucocorticoid signaling in osteoblasts and osteocytes prevents mechanical unloading-induced cortical bone loss

(2019) Jiancheng Yang et al.   BONE

A natural small molecule inhibitor corilagin blocks HCV replication and modulates oxidative stress to reduce liver damage

(2018) B. Uma Reddy et al.   ANTIVIRAL RESEARCH

Corilagin, a promising medicinal herbal agent

(2018) Xuan Li et al.   BIOMEDICINE & PHARMACOTHERAPY

Sophocarpine attenuates wear particle-induced implant loosening by inhibiting osteoclastogenesis and bone resorption via suppression of the NF-κB signalling pathway in a rat model

(2018) Chen-he Zhou et al.   BRITISH JOURNAL OF PHARMACOLOGY

Corilagin Attenuates Allergy and Anaphylactic Reaction by Inhibiting Degranulation of Mast Cells

(2018) Jie Zhou et al.   MEDICAL SCIENCE MONITOR

A Matrine Derivative M54 Suppresses Osteoclastogenesis and Prevents Ovariectomy-Induced Bone Loss by Targeting Ribosomal Protein S5

(2018) Zhi Xin et al.   Frontiers in Pharmacology

Tomatidine suppresses osteoclastogenesis and mitigates estrogen deficiency-induced bone mass loss by modulating TRAF6-mediated signaling

(2018) Bin Hu et al.   FASEB JOURNAL

Action of corilagin on hyperglycemia, hyperlipidemia and oxidative stress in streptozotocin-induced diabetic rats

(2018) H.S. Nandini et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Matrine prevents bone loss in ovariectomized mice by inhibiting RANKL-induced osteoclastogenesis

(2017) Xiao Chen et al.   FASEB JOURNAL

TNF-α promotes osteoclastogenesis through JNK signaling-dependent induction of Semaphorin3D expression in estrogen-deficiency induced osteoporosis

(2017) Chenglin Sang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Corilagin sensitizes epithelial ovarian cancer to chemotherapy by inhibiting Snail-glycolysis pathways

(2017) Luoqi Jia et al.   ONCOLOGY REPORTS

Hepatoprotective Effects of Corilagin Following Hemorrhagic Shock are Through Akt-Dependent Pathway

(2017) Fu-Chao Liu et al.   SHOCK

Apoptotic and genomic effects of corilagin on SKOV3 ovarian cancer cell line

(2017) Rukset Attar et al.   OncoTargets and Therapy

Matrine derivate MASM uncovers a novel function for ribosomal protein S5 in osteoclastogenesis and postmenopausal osteoporosis

(2017) Xiao Chen et al.   Cell Death & Disease

Antioxidant and pro-angiogenic effects of corilagin in rat cerebral ischemia via Nrf2 activation

(2017) Yi Ding et al.   Oncotarget

DC-STAMP: A Key Regulator in Osteoclast Differentiation

(2016) Ya-Hui Chiu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Animal models for osteoporosis

(2015) Toshihisa Komori   EUROPEAN JOURNAL OF PHARMACOLOGY

Management of severe osteoporosis

(2015) Paul D. Miller   EXPERT OPINION ON PHARMACOTHERAPY

Antiviral effects of Phyllanthus urinaria containing corilagin against human enterovirus 71 and Coxsackievirus A16 in vitro

(2014) Sang-Gu Yeo et al.   ARCHIVES OF PHARMACAL RESEARCH

A potential anti-tumor herbal medicine, Corilagin, inhibits ovarian cancer cell growth through blocking the TGF-β signaling pathways

(2013) Luoqi Jia et al.   BMC Complementary and Alternative Medicine

Corilagin inhibits hepatocellular carcinoma cell proliferation by inducing G2/M phase arrest

(2013) Yanlin Ming et al.   CELL BIOLOGY INTERNATIONAL

The impact of decreasing U.S. hip fracture rates on future hip fracture estimates

(2013) J. A. Stevens et al.   OSTEOPOROSIS INTERNATIONAL

Sensitization of Hep3B hepatoma Cells to Cisplatin and Doxorubicin by Corilagin

(2013) Roberto Gambari et al.   PHYTOTHERAPY RESEARCH

Molecular biology of bone remodeling: Implications for new therapeutic targets for osteoporosis

(2010) J. Chris Gallagher et al.   MATURITAS

Functions of RANKL/RANK/OPG in bone modeling and remodeling

(2008) Brendan F. Boyce et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

IL-23 promotes osteoclast formation by up-regulation of receptor activator of NF-κB (RANK) expression in myeloid precursor cells

(2008) Li Chen et al.   EUROPEAN JOURNAL OF IMMUNOLOGY