Nicotinic Cholinergic System and COVID-19: In Silico Identification of an Interaction between SARS-CoV-2 and Nicotinic Receptors with Potential Therapeutic Targeting Implications

Clinical predictors of mortality due to COVID-19 based on an analysis of data of 150 patients from Wuhan, China

(2020) Qiurong Ruan et al.   INTENSIVE CARE MEDICINE

Pathological findings of COVID-19 associated with acute respiratory distress syndrome

(2020) Zhe Xu et al.   Lancet Respiratory Medicine

Structural and Functional Basis of SARS-CoV-2 Entry by Using Human ACE2

(2020) Qihui Wang et al.   CELL

Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein

(2020) Alexandra C. Walls et al.   CELL

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

(2020) Markus Hoffmann et al.   CELL

The pivotal link between ACE2 deficiency and SARS-CoV-2 infection

(2020) Paolo Verdecchia et al.   European Journal of Internal Medicine

Systematic review of the prevalence of current smoking among hospitalized COVID-19 patients in China: could nicotine be a therapeutic option?

(2020) Konstantinos Farsalinos et al.   Internal and Emergency Medicine

Cytokine release syndrome in severe COVID-19: interleukin-6 receptor antagonist tocilizumab may be the key to reduce mortality

(2020) Chi Zhang et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Trials of anti-tumour necrosis factor therapy for COVID-19 are urgently needed

(2020) Marc Feldmann et al.   LANCET

Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study

(2020) Fei Zhou et al.   LANCET

COVID-19: consider cytokine storm syndromes and immunosuppression

(2020) Puja Mehta et al.   LANCET

Renin–Angiotensin–Aldosterone System Inhibitors in Patients with Covid-19

(2020) Muthiah Vaduganathan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Coronavirus disease 2019 (COVID-19) and anti-rheumatic drugs

(2020) Tsvetoslav Georgiev   RHEUMATOLOGY INTERNATIONAL

Smoking Upregulates Angiotensin-Converting Enzyme-2 Receptor: A Potential Adhesion Site for Novel Coronavirus SARS-CoV-2 (Covid-19)

(2020) Samuel James Brake et al.   Journal of Clinical Medicine

The cholinergic anti-inflammatory pathway: an innovative treatment strategy for respiratory diseases and their comorbidities

(2018) Mitsuhiro Yamada et al.   CURRENT OPINION IN PHARMACOLOGY

Varenicline is a smoking cessation drug that blocks alveolar expansion in mice intratracheally administrated porcine pancreatic elastase

(2018) Mitsuhisa Koga et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Galantamine anti-colitic effect: Role of alpha-7 nicotinic acetylcholine receptor in modulating Jak/STAT3, NF-κB/HMGB1/RAGE and p-AKT/Bcl-2 pathways

(2018) Shakeeb A. Wazea et al.   Scientific Reports

Cytokine release syndrome

(2018) Alexander Shimabukuro-Vornhagen et al.   Journal for ImmunoTherapy of Cancer

Nicotine and the Renin-Angiotensin System

(2018) Joshua M. Oakes et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Physiological functions of the cholinergic system in immune cells

(2017) Takeshi Fujii et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Expression and Function of the Cholinergic System in Immune Cells

(2017) Takeshi Fujii et al.   Frontiers in Immunology

A systematic review of possible serious adverse health effects of nicotine replacement therapy

(2016) Peter N. Lee et al.   ARCHIVES OF TOXICOLOGY

Galantamine protects against lipopolysaccharide-induced acute lung injury in rats

(2016) G. Li et al.   BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH

Pharmacological and molecular studies on the interaction of varenicline with different nicotinic acetylcholine receptor subtypes. Potential mechanism underlying partial agonism at human α4β2 and α3β4 subtypes

(2015) Hugo R. Arias et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Cytokines and chemokines: At the crossroads of cell signalling and inflammatory disease

(2014) Mark D. Turner et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Carbon monoxide in exhaled breath testing and therapeutics

(2013) Stefan W Ryter et al.   Journal of Breath Research

Nicotine treatment of mild cognitive impairment: A 6-month double-blind pilot clinical trial

(2012) P. Newhouse et al.   NEUROLOGY

Nicotine Reduces TNF-α Expression Through a α7 nAChR/MyD88/NF-ĸB Pathway in HBE16 Airway Epithelial Cells

(2011) Qi Li et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega

(2011) F. Sievers et al.   Molecular Systems Biology

Ligand-binding domain of an α7-nicotinic receptor chimera and its complex with agonist

(2011) Shu-Xing Li et al.   NATURE NEUROSCIENCE

Nicotine Exerts an Anti-inflammatory Effect in a Murine Model of Acute Lung Injury

(2010) Jon Mabley et al.   INFLAMMATION

Protective Effect of Nicotine on Lipopolysaccharide-Induced Acute Lung Injury in Mice

(2010) Yun Feng Ni et al.   RESPIRATION

Recent advances in understanding the structure of nicotinic acetylcholine receptors

(2009) Marios Zouridakis et al.   IUBMB LIFE

Requisite Role of the Cholinergic α7 Nicotinic Acetylcholine Receptor Pathway in Suppressing Gram-Negative Sepsis-Induced Acute Lung Inflammatory Injury

(2009) Xiao Su et al.   JOURNAL OF IMMUNOLOGY

Convergence of alpha 7 nicotinic acetylcholine receptor-activated pathways for anti-apoptosis and anti-inflammation: Central role for JAK2 activation of STAT3 and NF-κB

(2008) Mario B. Marrero et al.   BRAIN RESEARCH

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(2008) William Parrish et al.   MOLECULAR MEDICINE