Article
Public, Environmental & Occupational Health
Santosh Kumar Sidhwani, Talat Mirza, Ambrina Khatoon, Fouzia Shaikh, Rizma Khan, Omer Ahmed Shaikh, Abdulqadir J. Nashwan
Summary: This study aimed to investigate the correlation between inflammatory markers and the severity of COVID-19. The results showed a significant association between all markers, except procalcitonin, and disease severity. These findings could enhance our understanding of COVID-19 pathogenesis and aid in predicting and managing severe cases.
JOURNAL OF INFECTION AND PUBLIC HEALTH
(2023)
Review
Pharmacology & Pharmacy
Sevket Balta, Ilknur Balta
Summary: This review assesses the relationship between inflammatory markers and COVID-19 infection, including both known and emerging markers. These markers play important roles in follow-up, treatment response assessment, and risk stratification.
CURRENT VASCULAR PHARMACOLOGY
(2022)
Article
Medicine, General & Internal
Vanesa Seery, Silvina C. Raiden, Silvia C. Algieri, A. Grisolia, Daniela Filippo, Norberto De Carli, Sandra Di Lalla, Hector Cairoli, Maria J. Chiolo, Claudia N. Meregalli, Lorena I. Gimenez, Gabriela Gregorio, Mariam Sarli, Ana L. Alcalde, Carolina Davenport, Maria J. Bruera, Nancy Simaz, Mariela F. Perez, Valeria Nivela, Carola Bayle, Patricia Tuccillo, Maria T. Agosta, Hernan Perez, Susana Villa Nova, Patricia Suarez, Eugenia M. Takata, Mariela Garcia, Jorge Lattner, Maria J. Rolon, Patricia Coll, Ines Sananez, Maria P. Holgado, Fernando Ferrero, Jorge Geffner, Lourdes Arruvito
Summary: Neutrophils in children with COVID-19 exhibit a unique phenotype with high expression of inhibitory receptors and low expression of adhesion molecules, potentially preventing tissue infiltration. The expression of CD64 and serum IgG antibodies to the spike protein of SARS-CoV-2 can differentiate asymptomatic cases from mild and moderate cases of COVID-19.
Article
Biochemistry & Molecular Biology
Etienne Cavalier, Julien Guiot, Katharina Lechner, Alexander Dutsch, Mark Eccleston, Marielle Herzog, Thomas Bygott, Adrian Schomburg, Theresa Kelly, Stefan Holdenrieder
Summary: The study found elevated levels of nucleosomes in the plasma of COVID-19 patients, especially in those with severe disease. Increased citrullinated nucleosomes levels indicate neutrophil activation in severely affected individuals. Furthermore, nucleosome levels correlate with disease severity and may serve as a guiding biomarker for treatment.
FRONTIERS IN MOLECULAR BIOSCIENCES
(2021)
Article
Automation & Control Systems
Yonghang Tai, Kai Qian, Xiaoqiao Huang, Jun Zhang, Mian Ahmad Jan, Zhengtao Yu
Summary: A novel intelligent navigation technique combining AR, haptic feedback, and deep learning was developed for accurate image-guided COVID-19 lung biopsy. The model achieved high accuracy in classification and demonstrated superior performance compared to existing navigation techniques. The study opens up new avenues for integrating AR, haptic rendering, and deep learning in surgical navigation for COVID-19 interventions.
IEEE TRANSACTIONS ON INDUSTRIAL INFORMATICS
(2021)
Article
Biology
Iulia Cristina Bagiu, Ileana Luminita Scurtu, Delia Ioana Horhat, Ion Cristian Mot, Razvan Mihai Horhat, Radu Vasile Bagiu, Ionut Dragos Capraru, Mircea Mihai Diaconu, Ovidiu Adam, Bogdan Ciornei, Dan Dumitru Vulcanescu, Iulius Juganaru, Andrei-Cristian Bondar, Florin George Horhat
Summary: This study identified that CRP, LDH, and vitamin D levels are important biomarkers for COVID-19-positive pediatric patients, while CK levels were mostly within normal ranges. Clinical severity was associated with CRP, LDH, and vitamin D levels.
Article
Multidisciplinary Sciences
Giulia Besutti, Paolo Giorgi Rossi, Marta Ottone, Lucia Spaggiari, Simone Canovi, Filippo Monelli, Efrem Bonelli, Tommaso Fasano, Nicola Sverzellati, Andrea Caruso, Nicola Facciolongo, Giulia Ghidoni, Anna Simonazzi, Mauro Iori, Andrea Nitrosi, Stefania Fugazzaro, Stefania Costi, Stefania Croci, Elisabetta Teopompi, Annalisa Gallina, Marco Massari, Giovanni Dolci, Fabio Sampaolesi, Pierpaolo Pattacini, Carlo Salvarani
Summary: Inflammatory burden during COVID-19 is associated with residual lung CT abnormalities in severe COVID-19 pneumonia survivors, suggesting that inflammation is linked to short- and medium-term lung damage in COVID-19 patients.
SCIENTIFIC REPORTS
(2022)
Article
Medicine, General & Internal
Pere Trias-Sabria, Eduard Dorca Duch, Maria Molina-Molina, Samantha Aso, Marta Diez-Ferrer, Alfredo Marin Muniz, Jaume Bordas-Martinez, Joan Sabater, Patricio Luburich, Belen del Rio, Xavier Solanich, Jordi Dorca, Salud Santos, Guillermo Suarez-Cuartin
Summary: Lung ultrasound (LU) and chest CT scans can be used to identify the histological features of COVID-19 in patients with severe respiratory worsening. LU B2-lines and C-profile are associated with different CT patterns and histological findings of diffuse alveolar damage (DAD) and lung fibrosis.
FRONTIERS IN MEDICINE
(2022)
Article
Medicine, General & Internal
Cosmin Citu, Oana Maria Gorun, Andrei Motoc, Ioana Mihaela Citu, Florin Gorun, Daniel Malita
Summary: The study found that CRP, NLR, and IL-6 were significantly positively correlated with lung damage and had good accuracy in diagnosing severe lung involvement, with IL-6 having the highest AUC-ROC curve. These inflammatory markers can be used to evaluate the severity of COVID-19.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Multidisciplinary Sciences
Emily S. Lau, Jenna N. McNeill, Samantha M. Paniagua, Elizabeth E. Liu, Jessica K. Wang, Ingrid V. Bassett, Caitlin A. Selvaggi, Steven A. Lubitz, Andrea S. Foulkes, Jennifer E. Ho
Summary: In patients hospitalized with COVID-19 infection, men exhibited more robust inflammatory activation with higher levels of inflammatory markers and worse clinical outcomes compared to women. Gender may modify the association of peak CRP with death and ICU admission.
Review
Oncology
Chunhua Xu, Li Li, Wei Wang
Summary: The COVID-19 pandemic has posed challenges to lung cancer patients undergoing lung biopsies, requiring strict management of indications and personalized care to protect patients from the impact of the pandemic.
TECHNOLOGY IN CANCER RESEARCH & TREATMENT
(2021)
Article
Health Care Sciences & Services
Manuel Rubio-Rivas, Jose M. Mora-Lujan, Abelardo Montero, Josefa Andrea Aguilar Garcia, Manuel Mendez Bailon, Ana Fernandez Cruz, Isabel Oriol, Francisco-Javier Teigell-Munoz, Beatriz Dendariena Borque, Andres De la Pena Fernandez, Raquel Fernandez Gonzalez, Ricardo Gil Sanchez, Javier Fernandez Fernandez, Marta Catalan, Begona Cortes-Rodriguez, Carmen Mella Perez, Lorena Montero Rivas, Rebeca Suarez Fuentetaja, Jara Eloisa Ternero Vega, Javier Ena, Anabel Martin-Urda Diez-Canseco, Cristina Perez Garcia, Jose F. Varona, Jose Manuel Casas-Rojo, Jesus Millan Nunez-Cortes
Summary: Inflammatory cascade is the main cause of death in COVID-19 patients. Based on data from the Spanish SEMI-COVID-19 Registry, treatment with CS alone or CS plus TCZ should be based on the degrees of inflammation, with the combination reserved for high and very high-risk patients.
JOURNAL OF GENERAL INTERNAL MEDICINE
(2022)
Article
Health Care Sciences & Services
Ekaterina Sorokina, Alisa Pautova, Oleg Fatuev, Vladislav Zakharchenko, Alexander Onufrievich, Andrey Grechko, Natalia Beloborodova, Ekaterina Chernevskaya
Summary: Post-COVID-19 syndrome is a complex condition that leads to impairment in multiple body systems after COVID-19 infection. A study examined the clinical, laboratory, and gut disorders in patients with post-COVID-19 syndrome before and after a 14-day rehabilitation program. The results showed improvements in respiratory function, general well-being, and mood, but some metabolic and inflammatory variables did not fully recover during the program. The study also found imbalances in the gut microbiota of patients. The authors suggest that personalized rehabilitation programs should consider not only biomarker levels, but also the individual taxonomy of the gut microbiota.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Article
Medicine, General & Internal
Ali Razaghi, Attila Szakos, Marwa Alouda, Bela Bozoky, Mikael Bjornstedt, Laszlo Szekely
Summary: Critically ill COVID-19 patients with pleural effusion have a higher risk of longer hospitalization, multisystem inflammatory syndrome, and mortality. The study evaluated the pleural effusions of deceased COVID-19 patients and identified elevated levels of various protein markers, indicating overstimulation of the immune system and cytokine storm. The study also found damage to arterial and cardiovascular organs. Certain markers, such as CA12, CD40, IL-6, IL-8, PD-L1, and VEGFA, showed potential as biomarkers for disease severity and prognosis or as therapy targets. Additionally, the involvement of JAK/STAT pathways in hyperinflammation suggests the potential use of JAK inhibitors as an effective treatment.
Article
Immunology
Silke Lauren Sommen, Lise Beier Havdal, Joel Selvakumar, Gunnar Einvik, Truls Michael Leegaard, Fridtjof Lund-Johansen, Annika E. E. Michelsen, Tom E. E. Mollnes, Tonje Stiansen-Sonerud, Trygve Tjade, Vegard Bruun Bratholm Wyller, Lise Lund Berven
Summary: This study investigated immunological markers and pulmonary function in COVID-19 convalescents at 6 months after mild infection. The results showed that although there was an increase in chemokines among the COVID-19 convalescents, it was not associated with long-lasting symptoms of COVID-19.
FRONTIERS IN IMMUNOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Xueying Cao, Lanling Zhao, Bari Wulan, Dongxing Tan, Qianwu Chen, Jizhen Ma, Jintao Zhang
Summary: By utilizing the electrospun-pyrolysis cooperative strategy to modulate the porous structure of the carbon support and adjust the bridging structure of atomically dispersed metal species, the unique chemical structure of binuclear nickel bridging with nitrogen and carbon atoms has been identified to enhance CO2 reduction substantially.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Electrochemistry
Min Wang, Chengwei Cao, Fan Su, Yi Wang, Lu Liu, Wei Wang, Wei Zhang, Hailin Shen, Jintao Zhang
Summary: This study proposes an effective strategy to improve the cyclic stability and specific capacity of rechargeable aqueous Zn/MnO2 batteries through the synergistic effect of lithium ions pre-embedding and electrolyte additives. The results show that the lithium pre-embedded samples exhibit higher reversible capacity, outstanding cyclic stability, and promising rate performance. Furthermore, the addition of Li2SO4 additive enhances the cyclic stability and capacity of the battery.
ELECTROCHIMICA ACTA
(2022)
Article
Chemistry, Multidisciplinary
Yulong He, Miaomiao Liu, Song Chen, Jintao Zhang
Summary: By assembling and pyrolyzing metal-organic frameworks with nitrogen doping, hierarchical porous carbon fibers were prepared to inhibit the shuttle effect of polyiodide species. The self-supported carbon nanofiber electrode, benefitting from the confinement effect of the highly porous carbon network and nitrogen doping, achieved reversible two-step conversion between iodine and polyiodide.
SCIENCE CHINA-CHEMISTRY
(2022)
Review
Materials Science, Multidisciplinary
Alpha Chi Him Tsang, Jintao Zhang, Kwun Nam Hui, Kwan San Hui, Haibao Huang
Summary: Direct ink writing (DIW) is a low-cost and environmentally-friendly method for rapid design and construction of scalable 3D structures, utilizing optimized rheological properties and a wide range of nanomaterials to enhance performance. It has potential applications in medical, energy storage, and environmental treatment fields.
ADVANCED MATERIALS TECHNOLOGIES
(2022)
Article
Chemistry, Multidisciplinary
Shunping Ji, Jielei Li, Junfeng Li, Chunyan Song, Shuo Wang, Kexuan Wang, Kwan San Hui, Chenyang Zha, Yunshan Zheng, Duc Anh Dinh, Shi Chen, Jintao Zhang, Wenjie Mai, Zikang Tang, Zongping Shao, Kwun Nam Hui
Summary: Potassium-ion batteries (PIBs) are a promising alternative to lithium-ion batteries (LIBs) for large-scale electrochemical storage devices due to the abundance of potassium resources. However, PIB electrodes typically have low capacity and poor cyclic stability, as well as safety concerns. In this study, zinc phosphide composites are designed as PIB anodes in a nonflammable triethyl phosphate (TEP) electrolyte to address these issues. The optimized composite shows high specific capacity and excellent cycling performance, attributed to reversible dynamic evolutions and conversions of sulfur-containing species in the solid electrolyte interphase (SEI).
ADVANCED FUNCTIONAL MATERIALS
(2022)
Article
Engineering, Environmental
Qianwu Chen, Song Chen, Lanling Zhao, Jizhen Ma, Huaisheng Wang, Jintao Zhang
Summary: The modulation of interface properties through metal nitride coating provides new insights for stabilizing the lithium metal anode and enhancing the reversibility of lithium batteries.
CHEMICAL ENGINEERING JOURNAL
(2022)
Article
Chemistry, Multidisciplinary
Song Chen, Qianwu Chen, Jizhen Ma, Jianjun Wang, Kwan San Hui, Jintao Zhang
Summary: The dynamic coordination chemistry of phytic acid with zinc ions can modulate the interfacial redox process of zinc, improving the cycling stability and specific capacity of aqueous zinc batteries.
Article
Chemistry, Physical
Bari Wulan, Lanling Zhao, Dongxing Tan, Xueying Cao, Jizhen Ma, Jintao Zhang
Summary: It has been demonstrated that the electrochemical transformation of bismuth sulfide nanorods can lead to the formation of a three-dimensional bismuth nanosheet network on functionalized carbon fibers, improving the performance of the carbon dioxide reduction reaction. The hierarchical bismuth nanosheet network shows high selectivity, large current density, and good long-term stability.
ADVANCED ENERGY MATERIALS
(2022)
Article
Chemistry, Applied
Xinxin Shu, Maomao Yang, Miaomiao Liu, Wei Pan, Jintao Zhang
Summary: The coordination structure of cobalt with nitrogen atoms on reduced graphene oxide (rGO) sheets was successfully regulated by a bridging strategy involving interfacial complexation and thermal treatment. The well-dispersed cobalt-nitrogen coordination structure on rGO enables efficient oxygen reduction and evolution reactions, leading to the excellent performance of the fabricated Zn-air battery in terms of power density and long-term stability.
JOURNAL OF ENERGY CHEMISTRY
(2022)
Article
Immunology
Dong Zhang, Hui Yang, Xue-Li Dong, Jin-Tao Zhang, Xiao-Fei Liu, Yun Pan, Jian Zhang, Jia-Wei Xu, Zi-Han Wang, Wen-Jing Cui, Liang Dong
Summary: The TL1A/DR3 axis is closely associated with TNF-a expression in asthma and plays a role in exacerbating epithelial-mesenchymal transformation (EMT). Inhibiting or interfering with the TL1A/DR3 axis may have therapeutic potential for improving EMT in asthma.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Chemistry, Multidisciplinary
Bari Wulan, Xueying Cao, Dongxing Tan, Xinxin Shu, Jintao Zhang
Summary: This study focuses on the rational design of electrocatalysts for integrated energy devices, specifically through the coordination of organic ligands with metal ions to anchor metal atoms in carbon materials. The resulting electrocatalyst shows promising performance in various electrocatalytic activities and demonstrates high CO faradaic efficiency. The research also reveals the potential for solar cells to achieve higher conversion efficiency through the use of these electrocatalysts.
ADVANCED FUNCTIONAL MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Dongxing Tan, Bari Wulan, Jizhen Ma, Xueying Cao, Jintao Zhang
Summary: The electrocatalytic efficiency for synchronous formate generation can be improved by modifying the interface of cuprous oxide with polyvinylpyrrolidone (PVP). Density functional theory calculations show that the interfacial properties can be effectively regulated by PVP functionalization to improve the selectivity of formate generation. The advanced electrocatalysis enables efficient coupling of CO2 reduction with methanol oxidation in a solar cell-powered electrochemical cell.
Article
Chemistry, Physical
Hong Li, Xinxin Shu, Haolong Xi, Zhengxing Lv, He Tian, Jintao Zhang, Haibing Xia
Summary: Fe-Cu diatomic nanoclusters with sizes of 0.5-2.5 nm were prepared by chelation interaction and doping interaction. They were proposed as a new type of active site for oxygen reduction reaction (ORR). The as-prepared catalysts showed enhanced electrocatalytic performance and better stability compared to commercial Pt/C catalysts.
JOURNAL OF MATERIALS CHEMISTRY A
(2022)
Article
Allergy
Jintao Zhang, Dong Zhang, Yun Pan, Xiaofei Liu, Jiawei Xu, Xinrui Qiao, Wenjing Cui, Liang Dong
Summary: The TL1A-DR3 axis plays an important role in asthma, especially in its secreted form. The study indicates that TL1A is involved in airway remodeling. The TL1A-DR3 axis may regulate the development of asthma through the nuclear factor-kappa B pathway.
ALLERGY ASTHMA & IMMUNOLOGY RESEARCH
(2022)
Review
Endocrinology & Metabolism
Rong Zeng, Zihan Wang, Jintao Zhang, Ziting Liang, Changjuan Xu, Jing Wang, Liang Dong
Summary: Our meta-analysis suggests a possible association between type 1 diabetes and asthma, and patients who were previously diagnosed with asthma carried higher odds of developing type 1 diabetes.
