Article
Biotechnology & Applied Microbiology
Jieteng Chen, Weishun Zeng, Jing Gan, Yunxue Li, Yifan Pan, Junyan Li, Hao Chen
Summary: The study investigated the effects of different extraction conditions on the yields, chemical composition, rheological properties, and antioxidant activities of ulvan. Enzyme and ultrasonic treatment improved extraction yields and affected the composition of ulvan, with enzyme-assisted extraction showing the highest DPPH radical scavenging ability. The physicochemical properties of ulvan were significantly influenced by extraction methods, highlighting potential applications in healthcare due to its antioxidative properties.
ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS
(2021)
Article
Chemistry, Applied
Yu Han, Yulin Wu, Guoqiang Li, Meiying Li, Ru Yan, Zhenlin Xu, Hongtao Lei, Yuanming Sun, Xuewu Duan, Lianmei Hu, Riming Huang
Summary: The study found that three polysaccharides extracted from seaweed have significant effects on macrophages, especially UPP-1, which can promote cell proliferation, phagocytic activity, nitric oxide release, and cytokine secretion. Furthermore, UPP-1 also affects the genes and metabolism of macrophages, involving pathways such as amino acid synthesis, glycerophospholipid metabolism, and carbon metabolism.
Article
Chemistry, Medicinal
Yuzhou Wan, Lin Liu, Bo Zhang, Shaopeng Wang, Xiaoqian Wang, Kexu Chen, Yuxi Li, Tingting Zhao, Huimin Qi
Summary: This study elucidated the main structure of the high-sulfated derivative of Ulva pertusa polysaccharide (HU) and explored its therapeutic effect against nonalcoholic fatty liver disease (NAFLD). Results showed that HU effectively reduced blood lipid levels, improved liver function, decreased lipid droplets in the liver, and suppressed the abnormal enlargement of epididymal fat cells. HU appears to have a protective effect on the development of NAFLD.
Article
Biotechnology & Applied Microbiology
Tiancheng Tang, Chen Li, Benwei Zhu, Zhong Yao
Summary: Ulvan lyase ULA-3 from Alteromonas sp. 76-1 was cloned, heterologously expressed and characterized in this study. ULA-3 showed optimal activity at 45 °C and pH 9.0, with a Km of 1.879 mg mL(-1) and Vmax of 2.597 μmol min(-1) mL(-1). Its enzyme activity was 11.754 U mg(-1). The enzyme displayed excellent metal ion stability and was able to degrade ulvan into oligosaccharides with a Dp of 2-4 and unsaturated double bonds. This study expands the ulvan lyase database and provides opportunities for utilizing ulvan as a green biomass resource.
JOURNAL OF APPLIED PHYCOLOGY
(2023)
Article
Agriculture, Multidisciplinary
Xiaoqing Li, Yihan Chen, Xiaoxiang Gao, Yijing Wu, Hesham Rushdy El-Seedi, Yong Cao, Chao Zhao
Summary: A novel polysaccharide from Ulva lactuca (ULP) was found to exhibit antihyperuricemic activity by regulating biochemical indexes, gene expressions, tissue pathology, and gut microbiota. It effectively reduced serum uric acid levels, improved renal injury, and showed potential in treating hyperuricemia-related diseases.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2021)
Review
Biotechnology & Applied Microbiology
Tiancheng Tang, Shengsheng Cao, Benwei Zhu, Qian Li
Summary: Ulvan from marine green algae has potential in various fields and can be degraded by ulvan lyase to produce oligosaccharides with beneficial effects. Studies on ulvan lyases have identified four families of lyases and demonstrated their structural features, aiding in understanding their catalytic mechanisms.
ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS
(2021)
Article
Chemistry, Medicinal
Danni Wang, Yujiao Li, Lu Han, Chengying Yin, Yongqing Fu, Qi Zhang, Xia Zhao, Guoyun Li, Feng Han, Wengong Yu
Summary: This thesis explores the properties of a new polysaccharide lyase family 25 ulvan lyase TsUly25B from the marine bacterium Thalassomonas sp. LD5. It is salt-tolerant and exhibits high thermal stability. TsUly25B adopts an endolytic manner to degrade ulvan polysaccharides and produces unsaturated ulvan disaccharides and tetrasaccharides. This research enriches the ulvan lyase library and advances the utilization of ulvan lyases in further fundamental research and production of ulvan oligosaccharides.
Article
Agriculture, Dairy & Animal Science
Monica M. Costa, Luis B. Pio, Pedro Bule, Vania A. Cardoso, Marlene Duarte, Cristina M. Alfaia, Diogo F. Coelho, Joana A. Bras, Carlos M. G. A. Fontes, Jose A. M. Prates
Summary: This study evaluated the potential of an enzyme called ulvan lyase to degrade the cell walls of green macroalgae and release nutritive compounds. The results showed that ulvan lyase was the most efficient enzyme in disrupting the cell walls and promoting the release of reducing sugars and monosaccharides. However, there was no significant release of fatty acids, proteins, or pigments. These findings suggest that ulvan lyase has the potential to enhance the bioaccessibility of bioactive products from green macroalgae for use in the feed industry.
Article
Biochemistry & Molecular Biology
Chen Li, Tiancheng Tang, Jinju Jiang, Zhong Yao, Benwei Zhu
Summary: Ulva is a globally distributed specie with high economic value. This study explores a putative ulvan lyase from Alteromonas sp. KUL_42 and characterizes its properties. The results showed that the ulvan lyase had high catalytic activity and could maintain its activity within a certain temperature range. This study enriches the ulvan lyase library and promotes the development and utilization of Ulva resources.
Article
Green & Sustainable Science & Technology
N. Arul Manikandan, Piet N. L. Lens
Summary: A green strategy using citric acid as both an extractant and a cross-linking agent was developed to extract and esterify ulvan from two different morphologies of seaweed, foliose and filamentous Ulva sp., for hydrogel preparation. The optimized extraction process parameters yielded superior ulvan extraction compared to conventional hydrochloric acid and water-based methods. The extracted ulvan was characterized and used to prepare hydrogels with promising applications in various fields.
JOURNAL OF CLEANER PRODUCTION
(2022)
Article
Chemistry, Medicinal
Sujian Cao, Yajing Yang, Shan Liu, Zhuling Shao, Xiao Chu, Wenjun Mao
Summary: This study obtained a sulfated polysaccharide, UCP, from the green alga Ulva conglobata Kjellman and characterized its structure and immunomodulatory activity. The results showed that UCP has potential immunomodulatory effects and can improve immune suppression.
Article
Biotechnology & Applied Microbiology
Fei Xu, Fang Dong, Xiao-Hui Sun, Hai-Yan Cao, Hui-Hui Fu, Chun-Yang Li, Xi-Ying Zhang, Andrew McMinn, Yu-Zhong Zhang, Peng Wang, Xiu-Lan Chen
Summary: Ulvan is an important marine polysaccharide and bacterial ulvan lyases play crucial roles in its degradation. A new ulvan lyase, Uly1, belonging to polysaccharide lyase family 24, from the marine bacterium Catenovulum maritimum has been characterized. The study provides new insights into ulvan lyases and their degradation mechanisms.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
(2021)
Article
Chemistry, Applied
Joel T. Kidgell, Susan M. Carnachan, Marie Magnusson, Rebecca J. Lawton, Ian M. Sims, Simon F. R. Hinkley, Rocky de Nys, Christopher R. K. Glasson
Summary: The study revealed significant differences in the yield, iduronic acid content, molecular weight, and storage moduli of ulvans from blade and filamentous Ulva species, highlighting the variability of their physicochemical properties and morphology-based division within the genus Ulva.
CARBOHYDRATE POLYMERS
(2021)
Review
Biotechnology & Applied Microbiology
Chen Li, Tiancheng Tang, Yuguang Du, Ling Jiang, Zhong Yao, Limin Ning, Benwei Zhu
Summary: Ulvan, the primary component polysaccharide of Ulva cell wall, has complex structure and varied biological activities. However, the extraction and utilization of ulvan have been hindered by issues such as large molecular weight and low solubility. Ulva oligosaccharides obtained by degrading ulvan can effectively address these problems and retain the biological activities. Nevertheless, there is a shortage of comprehensive reviews on ulvan and Ulva oligosaccharides.
BIORESOURCES AND BIOPROCESSING
(2023)
Article
Chemistry, Applied
Hao Tang, Jinwen Huang, Qingxia Yuan, Kunling Lv, Haiqiong Ma, Tingting Li, Yonghong Liu, Shunli Mi, Longyan Zhao
Summary: In this study, a novel polysaccharide (CPP-1) was isolated from Chlorella pyrenoidosa and sulfated, showing potential as an anticoagulant. CPP-1 was mainly composed of D-mannopyranose, 3-O-methylated D-mannopyranose, and D-galactopyranose. The sulfated Chlorella mannogalactan (SCM) derived from CPP-1 demonstrated strong anticoagulant activity, making it a possible safer alternative to heparin-like drugs.
CARBOHYDRATE POLYMERS
(2023)
Article
Chemistry, Analytical
Guohui Wei, Xianjun Fu, Zhenguo Wang
Summary: This study developed a classification model using compound data set and molecular descriptors to predict the cold-hot-neutral nature of CHM compounds, demonstrating high predictive accuracy of the model.
JOURNAL OF AOAC INTERNATIONAL
(2021)
Article
Chemistry, Analytical
Xian Fu, Yu Wang, Bing Xia, Peiyu Shi, Yan Zhou
Summary: The newly developed USD-MS technique showed promising results in analyzing tissues with different morphologies and performed well in analyzing liver tumors and paracancerous tissues. Additionally, the method caused minimal tissue damage during analysis, allowing rats and mice with orthotopic tumors to survive after the experiments.
ANALYTICAL CHEMISTRY
(2021)
Article
Plant Sciences
Shan He, Tianqi Wang, Congwei Shi, Zhenguo Wang, Xianjun Fu
Summary: The study found that Danshen has 115 chemical targets related to anemia, with its treatment mechanism significantly linked to the Jak-STAT signaling pathway. Experimental results showed that Danshen extracts could enhance red blood cell count, cardiac output, and blood flow velocity, with Danshen aqueous extract exhibiting a wider range of anti-anemia effects and lower toxicity.
JOURNAL OF ETHNOPHARMACOLOGY
(2022)
Article
Biotechnology & Applied Microbiology
Shan He, Wei-Bing Peng, Xian-Jun Fu, Hong-Lei Zhou, Zhen-Guo Wang
Summary: Deep sea water (DSW) has been found to contain beneficial minerals that can improve cognitive impairment and reduce the hyperphosphorylation of Tau protein by activating the Akt/GSK-3p signaling pathway. These experimental results suggest that DSW may be explored as a natural neuroprotective food for the prevention and treatment of Alzheimer's disease (AD).
MARINE BIOTECHNOLOGY
(2022)
Review
Materials Science, Biomaterials
Li Qiao, Huishu Yang, Shijie Gao, Le Li, Xianjun Fu, Qingcong Wei
Summary: Nanodrug delivery systems combined with self-assembly technology are attracting increasing attention due to their advantages, and are expected to have potential therapeutic value in the field of biomedicine in the future.
JOURNAL OF MATERIALS CHEMISTRY B
(2022)
Article
Medicine, Research & Experimental
Wen-Wen Zhang, Hong Cao, Yang Li, Xian-Jun Fu, Yu-Qiu Zhang
Summary: This study reveals the important role of peripheral adenylyl cyclase isoform AC3 in nociceptive transmission and regulation of opioid receptor signaling. The conditional knockout of AC3 in mouse DRGs led to increased nociceptive responses, decreased Kv channel currents, and increased neuronal excitability. Furthermore, AC3 knockout abolished the analgesic effect of KOR agonist and its inhibition on Kv channel, suggesting the involvement of AC3 in KOR opioid analgesia through classical G alpha(i/o) signaling or direct interaction with KOR. Additionally, the upregulation of AC1 and cAMP levels in AC3-deficient DRGs highlights the compensatory role of AC1 in the absence of AC3.
Review
Plant Sciences
Yang Liu, Bao-Guo Li, Yu-Hua Su, Ruo-Xi Zhao, Peng Song, Hui Li, Xin-Hai Cui, Hong-Mei Gao, Run-Xiang Zhai, Xian-Jun Fu, Xia Ren
Summary: This review provides an overview of the application of traditional Chinese medicine (TCM) in the treatment of ulcerative colitis (UC). Through regulating inflammatory cytokines, intestinal flora, immune system, and protecting the intestinal mucosa, TCM has shown therapeutic effects in treating UC.
JOURNAL OF ETHNOPHARMACOLOGY
(2022)
Review
Medicine, Research & Experimental
Li Qiao, Huishu Yang, Xin-xin Shao, Qiuyan Yin, Xian-Jun Fu, Qingcong Wei
Summary: Glioma is the most common and aggressive primary intracranial tumor within the central nervous system. The blood-brain barrier has been a major obstacle for effective glioma treatment. Nanocarrier-mediated drug delivery has emerged as an effective and noninvasive system for treating glioma, showing great potential in glioma therapy.
MOLECULAR PHARMACEUTICS
(2022)
Article
Materials Science, Multidisciplinary
Pinhong Chen, Muyuan Chai, Zhuoxian Mai, Minjian Liao, Xiaoqi Xie, Zhiwei Lu, Weiqi Zhang, Hui Zhao, Xianming Dong, Xianjun Fu, Frank Ko, Xuetao Shi, Wenxu Zheng, Wuyi Zhou
Summary: Nanofiberous membranes incorporated with curcumin, tannic acid and silver nanoparticles were successfully fabricated by electrospinning. Characterization and analysis showed that the obtained composite membranes had good physicochemical properties and biocompatibility, making them suitable for wound prevention against free radicals and bacteria.
MATERIALS TODAY COMMUNICATIONS
(2022)
Article
Plant Sciences
Libing Hu, Fei Zhou, Xianjun Fu
Summary: This paper studies the texture synthesis method of ecological plant protection image based on convolutional neural network and verifies the superiority of this method through experiments.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Chemistry, Medicinal
Shan He, Wei-Bing Peng, Hong-Lei Zhou, Xian-Jun Fu, Yan-Hua Sun, Zhen-Guo Wang
Summary: This study investigates the regulatory mechanism of Fucoidan and deep-sea water (DSW) co-administration on type 2 diabetes (T2DM). Results show that the combination can effectively inhibit weight loss, decrease fasting blood glucose and lipids levels, and improve hepatopancreatic pathology and abnormal signaling pathways.
Article
Medicine, Research & Experimental
Zhihong Deng, Lifeng Zhao, Xiuxue Li, Chang-Yun Wang, Yue Zhou, Mengfei Li, Yingfei Li, Xianjun Fu
Summary: This study investigated the effects and mechanisms of an extract from the folium crataegi plant for burn wound treatment. The results showed that the aqueous extract had better therapeutic effects than the alcoholic extract. The extract promoted wound healing through anti-inflammatory, antioxidant and antibacterial effects, and may also involve regulation of the circadian rhythm pathway.
BIOMEDICINE & PHARMACOTHERAPY
(2023)
Review
Multidisciplinary Sciences
Xia Ren, Chun-Xiao Yan, Run-Xiang Zhai, Kuo Xu, Hui Li, Xian-Jun Fu
Summary: Traditional Chinese medicine (TCM) is limited in clinical application due to the difficulty in elucidating effective substances and lack of scientific evidence. Network pharmacology based on drug systems research provides a new approach for understanding TCM's complex systems. This review introduces commonly used web tools for compound-target interaction prediction in TCM pharmacology research and compares and analyzes their basic properties.
Article
Spectroscopy
Guohui Wei, Xianjun Fu, Zhenguo Wang, Honglei Zhou
Summary: The nature theory of Chinese medicine is a core basic theory of traditional Chinese medicine, and chemical fingerprint technology has been widely used in the identification and research of Chinese medicine. A predictive identification model was studied based on a constructed Chinese medicine fingerprint database to classify the cold-hot nature of Chinese medicines, proving to be effective with better predictive stability and extrapolation compared to existing classical models.
Article
Chemistry, Multidisciplinary
Guohui Wei, Xianjun Fu, Xueying He, Peng Qiu, Lu Yue, Rong Rong, Zhenguo Wang
Summary: This study analyzed the chemical components of 61 Chinese herbal medicines using GC technology and constructed a predictive identification model through distance metric learning algorithm and improved k-nearest neighbor algorithm, confirming the relationship between the "cold-hot nature" of Chinese herbal medicines and the similarity of their chemical components, with better predictive performance than existing classical models.
Article
Biochemistry & Molecular Biology
Wei-Han Hui, Yen-Lin Chen, Shu-Wei Chang
Summary: Crosslinking affects the mechanical behavior and tissue metabolism of collagen-based tissues. Aging and diabetes alter the crosslinking type and density, thus changing tissue properties. High-connectivity enzymatic crosslinking and advanced-glycation end-products result in uniform deformation under daily activity, while low-connectivity enzymatic crosslinking does not. High-connectivity model displays more sliding, while AGEs induce instability in structures near the binding sites.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yao-Bin Ma, Xiao-Qiu Zhou, Wei-Dan Jiang, Pei Wu, Yang Liu, Shu-Wei Li, Ling Tang, Lu Zhang, Hai-Feng Mi, Lin Feng
Summary: Tea polyphenols (TPs) are an inexpensive feed additive that can protect the gill function of fish against Flavobacterium columnare (F. columnare) through various mechanisms, including suppression of oxidative stress, apoptosis, and inflammation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yan-Jia Guo, Jing-Ru Pang, Yu Zhang, Zhong-Rui Li, Xiao-Lin Zi, Hong-Min Liu, Ning Wang, Li-Juan Zhao, Ya Gao, Bo Wang, Piet Herdewijn, Cheng-Yun Jin, Ying Liu, Yi-Chao Zheng
Summary: This study identifies the conjugation of NEDD8 to LSD1 and its impact on GC cells, revealing the significance of LSD1 neddylation in GC.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Geum-Jae Jeong, Fazlurrahman Khan, Nazia Tabassum, Young-Mog Kim
Summary: Vibrio species are motile gram-negative bacteria commonly found in aquatic environments. They can adapt to environmental fluctuations and develop protective mechanisms against host immune systems. Different types of sigma and anti-sigma factors play important roles in regulating gene expression and virulence in Vibrio species.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Zahra Mohammadbagheri, Behrooz Movahedi, Shaghayegh Saeedi, Abbas Rahmati
Summary: In this study, a reusable biobased composite hydrogel was successfully synthesized and used for the removal of Tl(I) from aqueous solutions. The hydrogel exhibited high adsorption capacity and thermal stability, and the adsorption process was found to be thermodynamically spontaneous. The results demonstrated that the hydrogel can be reused multiple times without significant loss of its adsorption capacity.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Iqra Batool, Muhammad Imran, Ayesha Anwar, Farhan Ahmed Khan, Afrah E. Mohammed, Ashwag Shami, Hafiz Iqbal
Summary: Enzyme immobilization on ZnO/SnO2 and ZnO/SnO2/SA nanocomposites was studied, and the catalytic and biochemical characteristics of the immobilized enzyme were investigated. The results showed that ZnO/SnO2 and ZnO/SnO2/SA nanostructures are suitable carriers for enzyme immobilization.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Elias Mosaffa, Dhruvi Patel, Nasim Amiri Ramsheh, Rishikumar Indravadan Patel, Atanu Banerjee, Hossein Ghafuri
Summary: In this study, a unique 3D bead structure of adsorbent, composed of bacterial cellulose microfilaments reinforced chitosan adorned with melamine 2D plates, was synthesized for anionic dye removal. The adsorbent showed high specific surface area and abundant functional groups, resulting in exceptional adsorption capacity. The characteristics and optimal conditions of the adsorbent were assessed and analyzed.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Carolina Gismene, Jorge Enrique Hernandez Gonzalez, Marilia de Freitas Calmon, Andrey Fabricio Ziem Nascimento, Angela Rocio Nino Santisteban, Felipe Antunes Calil, Alana Della Torre da Silva, Paula Rahal, Rejane Maira Goes, Raghuvir Krishnaswamy Arni, Ricardo Barros Mariutti
Summary: Mammaliicoccus sciuri, a bacterium of clinical and veterinary relevance, expresses the virulence factor Exfoliative Toxin C (ExhC), which binds specifically to desmoglein-1 (Dsg1) and plays a role in tissue integrity. This study investigates the necrotic activity of ExhC and identifies a variant lacking necrotic potential but retaining enzymatic activity through mutagenesis experiments and crystal structure determination.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Bibhas K. Bhunia, Ashutosh Bandyopadhyay, Souradeep Dey, Biman B. Mandal
Summary: Intervertebral disc degeneration is a major cause of chronic low back pain and disability. Researchers have developed a bioactive silk-based hybrid hydrogel system functionalized with decellularized human Wharton's jelly extracellular matrix as bioactive cues. The hydrogels mimic the rheological and mechanical properties of the native nucleus pulposus tissue and support cell viability, proliferation, and tissue maturation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Qun Zhang, Yonggan Yan, Zhao Li, Jing Du, Kai Zhang, Liguo Zhang, Ting Wang, Alberto Bianco, Shaohua Ge, Baojin Ma
Summary: A new crosslinking strategy has been devised to construct injectable sodium alginate hydrogels, which can be regulated for injectability and have great potential in biomedical applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Seong Eun Hong, Ji-Soo Lee, Hyeon Gyu Lee
Summary: The potential of multi-layer nanoemulsions for improving the cellular uptake, antioxidant activity, and in vitro bioaccessibility of alpha-tocopherol was examined. The results showed that the multi-layer nanoemulsions significantly enhanced the cellular uptake and antioxidant activity of alpha-tocopherol compared to free coumarin 6. Furthermore, the use of chitosan and dextran sulfate as wall materials in the multi-layer nanoemulsions led to even higher cellular uptake, in vitro bioaccessibility, and antioxidant activity of alpha-tocopherol.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jingjing Yu, Yanhui Zhang, Ruoning Zhang, Yanxiang Gao, Like Mao
Summary: High internal phase emulsions (HIPEs) based on beeswax (BW) oleogels and octenyl succinic acid starch (OSA starch) were prepared by a simple one-step method. The results showed that oleogelation improved the stability and encapsulation capability of the HIPEs, which is significant for the development of novel healthy food.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Bi-Feng Yao, Xiu-Ju Luo, Jun Peng
Summary: The balanced and continuous fission and fusion of mitochondria, regulated by OPA1, are important for maintaining mitochondrial dynamics in cardiovascular disorders. Understanding the role of OPA1 in mitochondrial fusion can provide insights into the pathogenesis of cardiovascular diseases.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Gokul Paramasivam, Anandhavelu Sanmugam, Vishnu Vardhan Palem, Murugan Sevanan, Ananda Babu Sairam, Nachiappan Nachiappan, Buhyun Youn, Jung Sub Lee, Muthuchamy Nallal, Kang Hyun Park
Summary: Nanomaterials are being used to deliver therapeutic agents in living systems. Different nanotechnological applications such as immunosensors, immune assays, and drug delivery are being implemented using nanotechnology. Genomics plays a crucial role in selecting appropriate drugs for personalized cancer therapy. It helps in analyzing gene and protein expression, disease classification, and designing disease models. Delivering drugs to specific areas using nanoparticles is a challenging issue.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jing Li, Wei Wang, Han Wu, Feng Peng, Hui Gao, Ying Guan
Summary: In this study, CMH-based CPF films were prepared and their thermal and barrier properties were successfully regulated. The tensile strength and water vapor barrier property of CPF films were significantly improved, making them promising for food packaging applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)