Article
Chemistry, Physical
Shihao He, Qingye Meng, Shuangling Zhong, Yan Gao, Xuejun Cui
Summary: Smart drug carriers with targeted delivery and controlled release ability, such as the FA-RANCs developed in this study, have shown promising potential for delivering and releasing hydrophobic anti-cancer drugs in a controlled manner.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2022)
Article
Chemistry, Multidisciplinary
Rachel D. Field, Margaret A. Jakus, Xiaoyu Chen, Kelia Human, Xuanhe Zhao, Parag Chitnis, Samuel K. Sia
Summary: In this study, we have developed a microfluidic system that can trigger drug release using focused ultrasound. The microcapsules made of hydrogels can release drugs as desired and have shown biocompatibility and wireless triggerability.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Chemistry, Physical
Alireza Parvaresh, Zhila Izadi, Houshang Nemati, Hossein Derakhshankhah, Mehdi Jaymand
Summary: A redox-and pH-responsive magnetic hydrogel was developed for sustained and targeted delivery of doxorubicin. The hydrogel, based on alginate, was synthesized using Fe3O4 nanoparticles and cystamine through double crosslinking. The hydrogel exhibited controlled drug release behavior, strong interaction with human serum albumin, and increased anti-cancer activity over time.
JOURNAL OF MOLECULAR LIQUIDS
(2023)
Article
Chemistry, Applied
Abeer Abdulaziz H. Bukhari, Nadia H. Elsayed, M. Monier
Summary: The photo-crosslinkable hydrogel derived from cinnamoyl modified alginate shows potential as an efficient drug carrier with the ability to control drug release. The gel can be crosslinked without the need for initiators through UV exposure, and the extent of crosslinking can be adjusted through cinnamoyl functionalization or UV light exposure time.
CARBOHYDRATE POLYMERS
(2021)
Article
Chemistry, Multidisciplinary
Amit Fischer, Pu Zhang, Yu Ouyang, Yang Sung Sohn, Ola Karmi, Rachel Nechushtai, Eli Pikarsky, Itamar Willner
Summary: In this study, the assembly of ATP and miRNA-responsive DNA tetrahedra-functionalized carboxymethyl cellulose hydrogel microcapsules is presented. The microcapsules are selectively unlocked and release the loaded drugs in the presence of ATP or miRNA-141. The functionalized microcapsules with DNA tetrahedra nanostructures exhibit superior permeation into cells, particularly breast cancer cells. The stimuli-responsive, drug-loaded, DNA tetrahedra-modified microcapsules show superior and selective cytotoxicity toward cancer cells.
Article
Chemistry, Multidisciplinary
Shameer Pillarisetti, Veena Vijayan, Jayakumar Rangasamy, Rizia Bardhan, Saji Uthaman, In-Kyu Park
Summary: We report a multi-stimulus responsive alginate nanogel that responds to changes in pH and redox potential in the tumor microenvironment. Combined with chemotherapy and photodynamic therapy (PDT), this nanogel enhances the therapeutic effect in breast cancer and melanoma by releasing a hydrophobic photosensitizer and a cytotoxic agent.
JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
(2023)
Article
Chemistry, Physical
Jilin Fan, Mingjun Xuan, Pengkun Zhao, Mark Loznik, Junlin Chen, Fabian Kiessling, Lifei Zheng, Andreas Herrmann
Summary: The development of ultrasound-responsive microcapsule structures has provided new insights into the development of ultrasound triggered small molecule drug delivery assisted by metallic nanoparticles. By employing nanodrugs encapsulated in microcapsules, drug leakage can be prevented and the delivery system can respond to high-intensity focused ultrasound.
Article
Chemistry, Physical
Jilin Fan, Mingjun Xuan, Pengkun Zhao, Mark Loznik, Junlin Chen, Fabian Kiessling, Lifei Zheng, Andreas Herrmann
Summary: The development of ultrasound-responsive microcapsule structures has enabled the controlled delivery of macromolecular cargoes for biomedical applications. However, delivering small molecular cargoes using microcapsules has been a challenge due to drug leakage. In this study, we proposed a new strategy by using nanodrugs encapsulated in microcapsules, which prevented drug leakage and provided responsiveness to ultrasound. Furthermore, we demonstrated the activation of antibacterial activity by ultrasound using the nanodrug@Microcapsules.
Article
Pharmacology & Pharmacy
Ahmed Gedawy, Giuseppe Luna, Jorge Martinez, Daniel Brown, Hani Al-Salami, Crispin R. Dass
Summary: A novel gliclazide-loaded elastomeric carbohydrate pharmaceutical vehicle was developed using a siliconized alginate platform. The microcapsules loaded with gliclazide showed excellent encapsulation efficiency (>92.13% +/- 0.76) and sustained drug release. The use of tetraethyl orthosilicate (TEOS) crosslinking improved the mechanical durability of the microcapsules.
Article
Materials Science, Multidisciplinary
Ekaterina Lengert, Mariia Saveleva, Roman Verkhovskii, Anna Abramova, Irina Goryacheva
Summary: The development of a novel system for water-insoluble glucocorticoid delivery shows promising results in improving bioavailability and sustained release, potentially reducing the number of injections needed and enhancing therapeutic outcomes for osteoarthritis treatment.
Article
Biochemistry & Molecular Biology
Zheng Wu, Jun Shi, Pingan Song, Jingguo Li, Shaokui Cao
Summary: In this study, a pH/NIR multi-responsive drug delivery platform was successfully fabricated using a layer-by-layer approach, consisting of hollow hydroxyapatite, chitosan/hyaluronic acid multilayers, gold nanorods, and MXene. The system exhibited excellent photothermal conversion efficiency and biocompatibility, with outstanding drug release performance under acidic conditions and effective activation by near-infrared light.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Engineering, Biomedical
Yonggang Zhang, Jiaping Li, Pamela Habibovic
Summary: In this study, a sandwich-structured magnetically responsive three-dimensional scaffold has been developed. The scaffold exhibits multimodal motion under external magnetic field and can be used as a smart carrier for remote-controlled compound delivery. It also shows good biocompatibility, making it a potential smart biomaterial for various biomedical applications.
BIOACTIVE MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Jean Schoeller, Fabian Itel, Karin Wuertz-Kozak, Sandra Gaiser, Nicolas Luisier, Dirk Hegemann, Stephen J. Ferguson, Giuseppino Fortunato, Rene M. Rossi
Summary: Surface functionalization of electrospun nanofibers allows for the introduction of additional functionalities while retaining high porosity and surface-to-volume ratio. In this study, chitosan and alginate were sequentially deposited on PLGA nanofibers to form a polyelectrolyte complex for controlled release of ibuprofen. Chitosan with a positive surface charge regulated the interactions between the drug and the coating, resulting in slower release at acidic pH compared to neutral pH.
Article
Chemistry, Physical
Qingye Meng, Shuangling Zhong, Shihao He, Yan Gao, Xuejun Cui
Summary: The study used an eco-friendly polysaccharide hyaluronic acid to design folic acid-modified microcapsules loaded with curcumin. These microcapsules showed good biocompatibility and targeting, avoiding side effects on normal tissues, with great potential for future clinical applications.
COLLOID AND INTERFACE SCIENCE COMMUNICATIONS
(2021)
Article
Chemistry, Applied
Huong Thi Hoang, Trung Thang Vu, Viswanathan Karthika, Sung-Han Jo, Yi-Jun Jo, Jeong-Woo Seo, Chul-Woong Oh, Sang-Hyug Park, Kwon Taek Lim
Summary: A physically and chemically double-crosslinked hydrogel derived from chitosan oligosaccharide/alginate was developed for the delivery of ketoprofen. The hydrogel showed outstanding hydrophobic drug loading and sustained release, as well as pH responsiveness, making it a potential candidate for hydrophobic drug delivery.
CARBOHYDRATE POLYMERS
(2022)
Article
Chemistry, Physical
Fen Qiao, Wenjie Liu, Jing Yang, Jiaren Yuan, Kaiyue Sun, Peng Fei Liu
Summary: In this paper, the chain-like structure of ZnO/ZnS heterojunction was prepared by electrospinning and ion exchange, and the influence of vulcanization degree on the hydrogen production of ZnO/ZnS was studied. The chain-like ZnO/ZnS heterojunction showed better photocatalytic hydrogen production performance compared to bare ZnO. This study provides practical reference value for the design of new composite photocatalysts and the study of catalytic mechanisms.
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
(2023)
Article
Physics, Multidisciplinary
M. Shoaib, I. Khan, S. M. Wabaidur, Md Ataul Islam, G. Rooh, N. Chanthima, I. Ullah, J. Kaewkhao, A. Ahad, Fen Qiao
Summary: This study prepares glasses with different chemical compositions and investigates their physical and luminescence properties. The findings show that the NSrFDy glass exhibits higher emission spectra intensity compared to the NSrODy glass, possibly due to the difference in OH concentrations and the energy transfer mechanism. The NSrFDy glass also demonstrates a high value of stimulated emission cross-section, making it a potential candidate for laser gain medium.
BRAZILIAN JOURNAL OF PHYSICS
(2023)
Article
Chemistry, Physical
Yan Zhao, Jihua Zheng, Jing Yang, Wenjie Liu, Fen Qiao, Jiabiao Lian, Guochun Li, Tao Wang, Jiangwei Zhang, Limin Wu
Summary: In this study, a unique hierarchical polypyrrole@cobalt sulfide (PPy-hs@CoS) hollow sphere-based nanofilm is prepared as interdigitated electrodes for flexible on-chip micro-supercapacitors (MSC). The PPy-hs@CoS composite material shows improved specific capacitance and resistance due to the great flexibility and high electrical conductivity of PPy-hs and the electrochemical activity of CoS. Density functional theory calculations confirm the synergistic effect of each component in enhancing reaction kinetics. The quasi-solid-state on-chip flexible MSC based on PPy-hs@CoS and activated carbon (AC) microelectrodes exhibits large areal-specific capacitance, ultrahigh energy density, and long cycle lifespan. By arranging two of the MSCs in series and parallel connections, the output voltage and current can be increased. Additionally, a self-charging system is developed by connecting the MSCs with a piece of commercial solar cells.
Article
Materials Science, Multidisciplinary
Jin-Zhi Hu, Wen-Jie Liu, Ji-Hua Zheng, Guo-Chun Li, Yong-Feng Bu, Fen Qiao, Jia-Biao Lian, Yan Zhao
Summary: In this study, a coral-like composite material was synthesized using electrostatic spinning combined with a wet chemical method. The composite exhibited a stable microstructure, exposed more active sites, and showed enhanced rate capability and cycling stability. This study provides a new preparation strategy for high-performance sodium-ion batteries.
Article
Thermodynamics
Yanzhen Liu, Qingping Li, Xin Lv, Lei Yang, Junfeng Wang, Fen Qiao, Jiafei Zhao, Huiping Qi
Summary: In deep-sea oil and gas transportation, kinetic inhibitors are used to prevent gas hydrates from clogging pipelines. However, clay particles can adsorb these inhibitors, reducing their effectiveness. This study found that 1:1-type layered silicates can only adsorb inhibitors through the surface, while 2:1-type layered silicates can adsorb inhibitors through both surface and intercalation. The adsorbed inhibitors make the clay particles aggregate and settle, weakening their inhibitory effect on gas hydrates.
Article
Chemistry, Physical
Wenjie Liu, Fen Qiao, Jing Yang, Jiaren Yuan, Yi Xie, Tao Wang, Jinzhi Hu, Jihua Zheng, Rui Ren, Xiaomin Kang, Yan Zhao, Jiangwei Zhang
Summary: A unique mesoporous heterostructure cobalt disulfide/carbon nanofibers (CoS2/PCNFs) composite with excellent hydrophilicity is prepared using polyethylene glycol (PEG) as a pore-forming agent. The CoS2/PCNF electrode exhibits excellent cycle stability, good rate performance, and high specific capacity. The unique CoS2/PCNF electrode is expected to be widely used in other electrochemical energy storage devices.
Article
Engineering, Chemical
Jing Yang, Heng-Quan Chen, Fen Qiao, Xifeng Zhu, Tao Wang, Wei-Ping Pan
Summary: Engineering metal-based nanoarchitectures and their atomic-scale arrangement is a promising avenue for enhanced mercury adsorbent activities. Interactions between metal single atoms and substrates result in regulated transitions between distinct reaction processes that boost mercury adsorption activity. This work contributed to a thorough comprehension of the structural and adsorption properties of the ZIF-derived Co3O4 sorbent engineering with a single atom and enabled the efficient capture of elemental mercury in flue gas by such ZIF-derived sorbent.
SEPARATION AND PURIFICATION TECHNOLOGY
(2023)
Article
Materials Science, Multidisciplinary
Jing Yang, Ji-Kang Zhao, Qing-An Sun, Yu Fan, Peng-Fei Liu, Fen Qiao
Summary: This study proposes a theoretical model based on the actual properties of silver nanoparticles (Ag NPs) and compares the MeHg adsorption properties of different surfaces ((1 1 1), (1 1 0), (1 0 0), and (2 1 1)) through first-principles theoretical study. It is found that each surface of the NPs has a strong affinity for MeHg despite differences in surface structure. The electronic charge density difference, partial density of states (PDOS), and Bader charge were investigated to understand the electron interaction of adsorbed MeHg with each surface of Ag NPs. The calculated energy barrier of MeHg diffusion on the facets of Ag NPs follows the trend of (1 0 0) > (1 1 0) > (2 1 1) > (1 1 1). The potential application of Ag NPs in MeHg removal in liquids is highly promising due to their superior diffusivity and high affinity for MeHg. This work provides a new strategy for using metal NPs as scavenger materials for MeHg in liquid conditions.
MATERIALS TODAY COMMUNICATIONS
(2023)
Article
Physics, Multidisciplinary
I. Khan, M. Shoaib, Munirah D. Albaqami, S. M. Wabaidur, Wazir Muhammad, G. Rooh, S. Kothan, N. Intachai, I. Ullah, E. Ahmad, F. Qiao, J. Kaewkhao
Summary: The emission, absorption, and decay time measurements of CaO-SrO-BaO-B2O3 glass doped with Ho3+ ions (BCBaSrHo) were studied. JO theory was used to evaluate the radiative properties of BCBaSrHo. The increase in density with Ho3+-ion concentration suggests a tightly packed and compact BCBaSrHo glass structure. The photoluminescence emission spectra of BCBaSrHo showed three emission transitions, and the BCBaSrHo(0.5) glass exhibited potential applications in green and red lasers.
BRAZILIAN JOURNAL OF PHYSICS
(2023)
Article
Engineering, Chemical
Jing Yang, Fen Qiao, Bin Li, Tao Wang, Chaoen Li, Jiang Wu, Dongjing Liu
Summary: Engineering the microstructure of sorbents to control their interfacial activity is a promising approach for enhancing mercury adsorption efficiency. In this study, carbon nitride microspheres (CNS) synthesized via hydrothermal route were used for Hg0 adsorption. A heterojunction structure was developed through density functional theory (DFT) calculations, leading to significantly improved mercury capture ability of CNS. The optimized 5CeO2/CNS composite exhibited a Hg0 removal efficiency of 98.3%, highlighting the effectiveness of constructing heterojunction interfaces to enhance mercury capture.
SEPARATION AND PURIFICATION TECHNOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Fen Qiao, Sen Qian, Wenjie Liu, Taihang Zhou, Jing Yang, Jikang Zhao, Jiaren Yuan
Summary: Cu2O with a cubic structure was used as a template to synthesize Cu2O/Cu2S core-shell material through the redox reaction of Cu2O and Na2S. The structure and photohydrogen production performance of Cu2O/Cu2S were studied by adjusting the sulfidization time. The flower-shaped hollow structure of Cu2O/Cu2S was obtained, and the hydrogen production reached 1076.95 μmol g(-1) after 5 hours of illumination. The Cu2O/Cu2S heterostructure improved the photoresponse ability and carrier transport properties, leading to enhanced photocatalytic hydrogen production.
Article
Chemistry, Multidisciplinary
Ling Li, Yuwei Zhong, Yongfei Hu, Jilin Bai, Fen Qiao, Abdelaal S. A. Ahmed, Ghafar Ali, Xiujian Zhao, Yi Xie
Summary: This study develops a facile room-temperature approach for the synthesis of environmentally friendly all-inorganic orange-red-emitting Ag-doped and Mn-doped lead-free halide double perovskite Cs2NaBiCl6 (CNBC) in the shape of an octahedron. Both Ag and Mn doping heavily enhance the photoluminescence intensity of the CNBC samples, and their stability is studied under various conditions. The photocatalytic performances of the samples are investigated, demonstrating a strong and stable photodegradation activity. This work provides a facile and cost-effective protocol for doped lead-free double perovskites as stable and environmentally friendly alternative photocatalysts.
Review
Chemistry, Multidisciplinary
Dunyuan Jin, Fen Qiao, Huaqiang Chu, Yi Xie
Summary: At present, the problems of high energy consumption and low efficiency in electrocatalytic hydrogen production have limited its large-scale industrial application. Constructing effective catalysts, particularly transition metal alloys, has been proven as a promising solution. This study summarizes the theories and characterization methods of electrocatalysis, analyzes the recent progress in using binary, ternary, and high entropy alloys for hydrogen evolution reaction (HER), and discusses the synthesis methods and optimization strategies for transition metal alloys in detail. Despite the significant progress, there is still considerable room for applications. Finally, the challenges, prospects, and research directions of transition metal alloys in the future are predicted.
Article
Materials Science, Multidisciplinary
Kai Peng, Liyan Liu, Narayanamoorthy Bhuvanendran, Fen Qiao, Guangping Lei, Sae Youn Lee, Qian Xu, Huaneng Su
Summary: Well-defined nickel-iron-vanadium layered double hydroxide nanosheets modified by sulfur incorporation (S-NiFeV LDH) on a nickel foam substrate were synthesized using a facile two-step hydrothermal method. The as-prepared S-NiFeV LDH catalyst shows superior electrocatalytic performance for the urea oxidation reaction, attributed to improved intrinsic activity, electrical conductivity, and large specific surface area.
MATERIALS ADVANCES
(2023)
Article
Materials Science, Multidisciplinary
Wen-Jie Liu, Ming Yuan, Jia-Biao Lian, Guo-Chun Li, Qiu-Ping Li, Fen Qiao, Yan Zhao
Summary: In this study, partially sulfurized iron-cobalt oxide nanoparticles were embedded in carbon nanofibers via electrospinning and hydrothermal sulfurization. The resulting FCOS@CNF samples with hierarchical nanostructure exhibited high specific capacitance, good rate performance, and long cycle lifespan when used as supercapacitor electrodes.
Article
Biochemistry & Molecular Biology
Wei-Han Hui, Yen-Lin Chen, Shu-Wei Chang
Summary: Crosslinking affects the mechanical behavior and tissue metabolism of collagen-based tissues. Aging and diabetes alter the crosslinking type and density, thus changing tissue properties. High-connectivity enzymatic crosslinking and advanced-glycation end-products result in uniform deformation under daily activity, while low-connectivity enzymatic crosslinking does not. High-connectivity model displays more sliding, while AGEs induce instability in structures near the binding sites.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yao-Bin Ma, Xiao-Qiu Zhou, Wei-Dan Jiang, Pei Wu, Yang Liu, Shu-Wei Li, Ling Tang, Lu Zhang, Hai-Feng Mi, Lin Feng
Summary: Tea polyphenols (TPs) are an inexpensive feed additive that can protect the gill function of fish against Flavobacterium columnare (F. columnare) through various mechanisms, including suppression of oxidative stress, apoptosis, and inflammation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yan-Jia Guo, Jing-Ru Pang, Yu Zhang, Zhong-Rui Li, Xiao-Lin Zi, Hong-Min Liu, Ning Wang, Li-Juan Zhao, Ya Gao, Bo Wang, Piet Herdewijn, Cheng-Yun Jin, Ying Liu, Yi-Chao Zheng
Summary: This study identifies the conjugation of NEDD8 to LSD1 and its impact on GC cells, revealing the significance of LSD1 neddylation in GC.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Geum-Jae Jeong, Fazlurrahman Khan, Nazia Tabassum, Young-Mog Kim
Summary: Vibrio species are motile gram-negative bacteria commonly found in aquatic environments. They can adapt to environmental fluctuations and develop protective mechanisms against host immune systems. Different types of sigma and anti-sigma factors play important roles in regulating gene expression and virulence in Vibrio species.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Zahra Mohammadbagheri, Behrooz Movahedi, Shaghayegh Saeedi, Abbas Rahmati
Summary: In this study, a reusable biobased composite hydrogel was successfully synthesized and used for the removal of Tl(I) from aqueous solutions. The hydrogel exhibited high adsorption capacity and thermal stability, and the adsorption process was found to be thermodynamically spontaneous. The results demonstrated that the hydrogel can be reused multiple times without significant loss of its adsorption capacity.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Iqra Batool, Muhammad Imran, Ayesha Anwar, Farhan Ahmed Khan, Afrah E. Mohammed, Ashwag Shami, Hafiz Iqbal
Summary: Enzyme immobilization on ZnO/SnO2 and ZnO/SnO2/SA nanocomposites was studied, and the catalytic and biochemical characteristics of the immobilized enzyme were investigated. The results showed that ZnO/SnO2 and ZnO/SnO2/SA nanostructures are suitable carriers for enzyme immobilization.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Elias Mosaffa, Dhruvi Patel, Nasim Amiri Ramsheh, Rishikumar Indravadan Patel, Atanu Banerjee, Hossein Ghafuri
Summary: In this study, a unique 3D bead structure of adsorbent, composed of bacterial cellulose microfilaments reinforced chitosan adorned with melamine 2D plates, was synthesized for anionic dye removal. The adsorbent showed high specific surface area and abundant functional groups, resulting in exceptional adsorption capacity. The characteristics and optimal conditions of the adsorbent were assessed and analyzed.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Carolina Gismene, Jorge Enrique Hernandez Gonzalez, Marilia de Freitas Calmon, Andrey Fabricio Ziem Nascimento, Angela Rocio Nino Santisteban, Felipe Antunes Calil, Alana Della Torre da Silva, Paula Rahal, Rejane Maira Goes, Raghuvir Krishnaswamy Arni, Ricardo Barros Mariutti
Summary: Mammaliicoccus sciuri, a bacterium of clinical and veterinary relevance, expresses the virulence factor Exfoliative Toxin C (ExhC), which binds specifically to desmoglein-1 (Dsg1) and plays a role in tissue integrity. This study investigates the necrotic activity of ExhC and identifies a variant lacking necrotic potential but retaining enzymatic activity through mutagenesis experiments and crystal structure determination.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Bibhas K. Bhunia, Ashutosh Bandyopadhyay, Souradeep Dey, Biman B. Mandal
Summary: Intervertebral disc degeneration is a major cause of chronic low back pain and disability. Researchers have developed a bioactive silk-based hybrid hydrogel system functionalized with decellularized human Wharton's jelly extracellular matrix as bioactive cues. The hydrogels mimic the rheological and mechanical properties of the native nucleus pulposus tissue and support cell viability, proliferation, and tissue maturation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Qun Zhang, Yonggan Yan, Zhao Li, Jing Du, Kai Zhang, Liguo Zhang, Ting Wang, Alberto Bianco, Shaohua Ge, Baojin Ma
Summary: A new crosslinking strategy has been devised to construct injectable sodium alginate hydrogels, which can be regulated for injectability and have great potential in biomedical applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Seong Eun Hong, Ji-Soo Lee, Hyeon Gyu Lee
Summary: The potential of multi-layer nanoemulsions for improving the cellular uptake, antioxidant activity, and in vitro bioaccessibility of alpha-tocopherol was examined. The results showed that the multi-layer nanoemulsions significantly enhanced the cellular uptake and antioxidant activity of alpha-tocopherol compared to free coumarin 6. Furthermore, the use of chitosan and dextran sulfate as wall materials in the multi-layer nanoemulsions led to even higher cellular uptake, in vitro bioaccessibility, and antioxidant activity of alpha-tocopherol.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jingjing Yu, Yanhui Zhang, Ruoning Zhang, Yanxiang Gao, Like Mao
Summary: High internal phase emulsions (HIPEs) based on beeswax (BW) oleogels and octenyl succinic acid starch (OSA starch) were prepared by a simple one-step method. The results showed that oleogelation improved the stability and encapsulation capability of the HIPEs, which is significant for the development of novel healthy food.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Bi-Feng Yao, Xiu-Ju Luo, Jun Peng
Summary: The balanced and continuous fission and fusion of mitochondria, regulated by OPA1, are important for maintaining mitochondrial dynamics in cardiovascular disorders. Understanding the role of OPA1 in mitochondrial fusion can provide insights into the pathogenesis of cardiovascular diseases.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Gokul Paramasivam, Anandhavelu Sanmugam, Vishnu Vardhan Palem, Murugan Sevanan, Ananda Babu Sairam, Nachiappan Nachiappan, Buhyun Youn, Jung Sub Lee, Muthuchamy Nallal, Kang Hyun Park
Summary: Nanomaterials are being used to deliver therapeutic agents in living systems. Different nanotechnological applications such as immunosensors, immune assays, and drug delivery are being implemented using nanotechnology. Genomics plays a crucial role in selecting appropriate drugs for personalized cancer therapy. It helps in analyzing gene and protein expression, disease classification, and designing disease models. Delivering drugs to specific areas using nanoparticles is a challenging issue.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jing Li, Wei Wang, Han Wu, Feng Peng, Hui Gao, Ying Guan
Summary: In this study, CMH-based CPF films were prepared and their thermal and barrier properties were successfully regulated. The tensile strength and water vapor barrier property of CPF films were significantly improved, making them promising for food packaging applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
