Article
Environmental Sciences
Christian M. Bako, Timothy E. Mattes, Rachel F. Marek, Keri C. Hornbuckle, Jerald L. Schnoor
Summary: The experiments showed that the aerobic PCB-degrading bacteria Paraburkholderia xenovorans LB400 can rapidly degrade most PCB congeners when they are freely dissolved in liquid, but cannot degrade PCB congeners with three or more chlorine substituents in sediment slurry. Using GC/MS-MS triple quadrupole spectrometry, the study distinguished between physical (sorption to cells) and biological removal mechanisms, and illuminated how microorganisms like LB400 can selectively transform lower-chlorinated congeners over time.
ENVIRONMENTAL POLLUTION
(2021)
Article
Chemistry, Physical
Qiang Yang, Jing Guo, Yuanfa Liu, Fucheng Guan, Fanchen Sun, Xueyong Gong
Summary: This study proposes a simple and convenient method for preparing P(3,4HB)/GEL composite nanofibrous (P/G-CNF) to improve the hydrophilicity and biocompatibility. The P/G-CNF was prepared using alkyl polyglycoside (APG) as an emulsifier. The results show that the P/G-CNF exhibits excellent micromorphology, enhanced crystallization and mechanical properties, improved hydrophilicity, and non-cytotoxicity.
SURFACES AND INTERFACES
(2022)
Article
Biochemistry & Molecular Biology
Anna Czerniecka-Kubicka, Marcin Skotnicki, Weronika Gonciarz, Iwona Zarzyka, Barbara Jadach, Lenka Lovecka, Karolina Maternia-Dudzik, Miroslava Kovarova, Marek Pyda, Piotr Tutka, Vladimir Sedlarik
Summary: Polymeric cytisine-enriched fibers were prepared using electrospinning method based on poly(3-hydroxybutyrate). The biocompatibility, thermal analysis, and cytisine release from the fibers were examined. The morphology of the nanofibers was evaluated using scanning electron microscopy. Advanced thermal analysis was conducted to study the phases and thermal processes of the fibers. Quantitative thermal analysis revealed the heat capacities and allowed for the study of the glass transition and melting/crystallization process of the polymeric fibers. The dissolution behavior of cytisine was also investigated, showing delayed release from the polymeric nanofibers compared to the marketed product. The immunosafety of the tested polymeric nanofibers with cytisine was confirmed by regulatory agencies. The polymeric matrix with cytisine holds promise as a prolonged release formulation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Polymer Science
Tao Zhang, Yunjae Jang, Eunhye Lee, Sooan Shin, Ho-Jong Kang
Summary: This study investigates the supercritical carbon dioxide foaming characteristics of the biodegradable polymer P(3HB-co-4HB) for environmentally friendly packaging materials. The effect of the 4HB composition on the foaming conditions, such as pressure and temperature, is studied, and the resulting foam density and expansion ratio are evaluated. Increasing the 4HB content reduces the crystallinity and tan delta value required for foam cell growth. Lower foaming temperatures are needed to maintain a suitable tan delta value. However, foaming is not possible when the 4HB content exceeds 50% due to a high tan delta value. Crystalline P(3HB-co-4HB) with low 4HB content results in lower foam density and higher expansion ratio compared to non-crystalline P(3HB-co-4HB) with high 4HB content. The addition of a chain extender slightly increases the expansion ratio by reducing crystallinity and tan delta, most effectively with a 4HB content of 16%.
Review
Polymer Science
Yuliya Zhuikova, Vsevolod Zhuikov, Valery Varlamov
Summary: The development of modern medical devices focuses on finding and creating new materials with better properties. Natural biopolymers, such as polyhydroxyalkanoates and polysaccharides, show potential in various applications. This article describes the properties of these biopolymers and explores the creation of polymer composites to overcome their drawbacks.
Article
Polymer Science
Anatoly A. Olkhov, Elena E. Mastalygina, Vasily A. Ovchinnikov, Tatiana Monakhova, Alexandre A. Vetcher, Alexey L. Iordanskii
Summary: Blending PHB and CHT forms a heterophase system with a non-equilibrium stressed structure, enhancing microbial growth; the antimicrobial properties of CHT inhibit biodegradation; nonwoven nanofiber materials have a larger specific surface area, leading to increased thermo-oxidative and biological degradation capabilities.
Article
Engineering, Environmental
Xueqi Chen, Caihua Bai, Zhiling Li, Di Cao, Yunxia Zu, Zimeng Zhang, Guanshu Zhao, Jun Nan, Hongcheng Wang, Bin Liang, Aijie Wang
Summary: The combination of slow-release organic carbon sources and bioelectrochemical dechlorination system can improve dechlorination efficiency, control organocarbon release, and achieve simultaneous pollution removal and resource recovery in chlorinated hydrocarbon contaminated field.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Polymer Science
Polina M. Tyubaeva, Ivetta A. Varyan, Anna K. Zykova, Alena Yu Yarysheva, Pavel Ivchenko, Anatoly A. Olkhov, Olga Arzhakova
Summary: This study successfully developed high-performance composite fibrous materials based on biodegradable polymers, improved the quality of the materials by adding natural iron-containing porphyrin, and showed high porosity and antibacterial potential. These materials can be used in medical applications such as wound disinfection, accelerated healing, and tissue engineering.
Article
Polymer Science
Teresa Marques-Almeida, Liliana C. Fernandes, Daniela M. Correia, Carmen R. Tubio, Senentxu Lanceros-Mendez, Clarisse Ribeiro
Summary: This study reports on electrospun fiber based membranes with tailored physical properties and morphology by combining piezoelectric and biodegradable polymers with poly(ethylene oxide). The produced materials demonstrated huge potential for environmental and biotechnological applications that require piezoelectricity, biodegradability, and porosity.
POLYMERS FOR ADVANCED TECHNOLOGIES
(2022)
Article
Biochemistry & Molecular Biology
Anatoly Aleksandrovich Olkhov, Elena Evgenyevna Mastalygina, Vasily Andreevich Ovchinnikov, Alexander Sergeevich Kurnosov, Anatoly Anatolyevich Popov, Alexey Leonidovich Iordanskii
Summary: Developing biodegradable materials based on polymer blends with a programmable self-destruction period is a promising direction in polymer chemistry. In this study, non-woven fibrous materials obtained by electrospinning based on the blends of PLA and PHB were developed, and their biodegradation kinetics in aquatic and ozone environments were investigated. The results showed that PHB was biodegradable while PLA remained stable, and the rate of ozone degradation was higher for PLA and blends with a high content of PLA. The optimal composition was found to be 30PLA/70PHB for various applications.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Environmental Sciences
Deepak Verma, Nichakan Nichakornpong, Unchalee Kraiwitwattana, Manunya Okhawilai, Pornnapa Kasemsiri, Pranut Potiyaraj, Ratthapol Rangkupan
Summary: In this study, a PM2.5 dust filter was developed using the electrospinning technique with a biopolymer called poly(3-hydroxybutyrate) (PHB). The filter showed high filtration efficiency and tensile strength, making it a potential candidate for PM2.5 filtration membrane production.
ENVIRONMENTAL RESEARCH
(2023)
Article
Materials Science, Multidisciplinary
Thammarit Khamplod, James B. B. Winterburn, Sarah H. H. Cartmell
Summary: Improving ACL rupture repair methods may reduce the occurrence of long-term osteoarthritis. Research has shown that scaffolds made from 3-hydroxybutyrate-co-3-hydroxyvalerate have good biomechanical and biodegradable properties. Materials with 50 mol% 3-hydroxyvalerate content have increased elasticity and can be aligned in a fiber network, which is desirable for ACL repair applications.
SCIENCE AND TECHNOLOGY OF ADVANCED MATERIALS
(2022)
Article
Polymer Science
Jin-Chuang Yang, Jun Yang, Tie-Ying Zhang, Xin-Jun Li, Xiao-Bing Lu, Ye Liu
Summary: The development of biodegradable and recyclable polymers has partially solved the problem of realizing a sustainable plastics economy. This study focuses on toughening poly(3-hydroxybutyrate) (P3HB), a highly crystalline thermoplastic material, by reducing its crystallinity through catalytic carbonylative terpolymerization with different enantiopure epoxides. The properties of the resulting PHA copolymers can range from viscous oil to tough/ductile and brittle plastics, depending on the structure and stereochemistry of the epoxides used.
Article
Polymer Science
Polina M. Tyubaeva, Kristina G. Gasparyan, Alexander Yu. Fedotov, Pavel V. Lobzhanidze, Oleg V. Baranov, Alexey A. Egorov, Vladimir P. Sirotinkin, Vladimir S. Komlev, Anatoly A. Olkhov
Summary: The aim of this study is to produce a highly filled fibrous nonwoven material composed of poly-3-hydroxybutyrate (PHB) and a-tricalcium (a-TCP) phosphate using electrospinning, and to investigate its morphology, structure, and properties. The addition of a-TCP significantly affected the supramolecular structure of the material, allowing control over crystallinity, and resulted in changes in mechanical properties, FTIR spectra, and XRD curves. These findings have the potential to contribute to the development of new osteoconductive materials that can release calcium into the living organism in a controlled manner.
Article
Materials Science, Characterization & Testing
David Fernandez Armada, Victoria Gonzalez Rodriguez, Pedro Costa, Senentxu Lanceros-Mendez, Goretti Arias-Ferreiro, Maria-Jose Abad, Ana Ares-Pernas
Summary: The development of new conducting composites with lower environmental impact for electric and electronic applications is an important issue. Blending PHBV with HDPE and MWCNTs and optimizing their dispersion and amount has resulted in composites with reduced environmental impact and suitable for EMI shielding applications.
Article
Engineering, Biomedical
Lorena Garcia-del Rio, Patricia Diaz-Rodriguez, Gabriel Kristian Pedersen, Dennis Christensen, Mariana Landin
Summary: This study proposes a novel strategy to enhance local immunity against Chlamydia trachomatis through subcutaneous and sublingual vaccination. A thermosensitive hydrogel with desirable properties is developed using artificial intelligence techniques to facilitate vaccine absorption. In vivo studies show that the combined vaccination approach enhances cellular immune responses and elicits local immune response in the genital tract.
ADVANCED HEALTHCARE MATERIALS
(2022)
Review
Biology
Maria Florencia Lezcano, Giannina Alvarez, Priscila Chuhuaicura, Karina Godoy, Josefa Alarcon, Francisca Acevedo, Ivan Gareis, Fernando Jose Dias
Summary: Polyhydroxybutyrate (PHB) scaffolds show promising potential in promoting peripheral nerve regeneration, and the incorporation of additives appears to enhance nerve regeneration. However, standardized experimentation on animals is currently lacking in the reviewed studies, making it necessary to follow guidelines, improve study design, and enhance research quality.
Article
Pharmacology & Pharmacy
Ines Sifaoui, Patricia Diaz-Rodriguez, Ruben L. Rodriguez-Exposito, Maria Reyes-Batlle, Atteneri Lopez-Arencibia, Lizbeth Salazar Villatoro, Ismael Castelan-Ramirez, Maritza Omana-Molina, Alexis Oliva, Jose E. Pinero, Jacob Lorenzo-Morales
Summary: The present study aimed to develop Pitavastatin loaded nanoparticles suitable for ophthalmic administration and designed for the management of Acanthamoeba Keratitis. The nanoparticles obtained through a nanoprecipitation-solvent displacement method showed good amoebicidal activity and could solve the issue of poor aqueous solubility of Pitavastatin.
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
(2022)
Article
Biochemistry & Molecular Biology
Javier Suarez-Gonzalez, Amor R. Caceres-Perez, Alexis Oliva, Ana Santovena-Estevez, Jose B. Farina
Summary: This study developed an ultra-performance liquid chromatography method for analyzing fixed combination tablets used for treating tuberculosis. The method was optimized and validated, and proved to be accurate and precise in detecting multiple active pharmaceutical ingredients, which is significant for ensuring the quality of drug products.
Article
Multidisciplinary Sciences
Amor R. Caceres-Perez, Mohamed B. El Kory, Javier Suarez-Gonzalez, Mabel Soriano, M. Magdalena Echezarreta, Ana Santovena-Estevez, Jose B. Farina
Summary: The quality of antituberculosis drug products in Mauritania is substandard, mainly due to non-compliance with quality control standards. European drug products, on the other hand, meet the pharmacopeia specifications. Storage conditions also affect the quality of the drugs.
Review
Nanoscience & Nanotechnology
Helena Rouco, Patricia Garcia-Garcia, Erik Briffault, Patricia Diaz-Rodriguez
Summary: Osteoclasts play a crucial role in the bone resorption process during bone remodeling. Osteoporosis, characterized by decreased bone mass density and altered bone microarchitecture, poses challenges in its treatment due to low patients' adherence to available therapies. Hence, the development of new and safe treatments, such as synthetic and natural nanoparticles, to modulate osteoclasts activity is necessary. Synthetic nanoparticles can carry antiresorptive drugs or regulate osteoclasts gene expression, while natural nanoparticles, known as extracellular vesicles, have been studied for their role in bone homeostasis. By controlling osteoclast activity using nanoparticles, the management of osteoporosis can be improved.
WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY
(2023)
Article
Chemistry, Physical
Angela Arnosa-Prieto, Patricia Diaz-Rodriguez, Manuel A. Gonzalez-Gomez, Pelayo Garcia-Acevedo, Lisandra de Castro-Alves, Yolanda Pineiro, Jose Rivas
Summary: Macrophages can exhibit different phenotypes depending on the microenvironment and the characteristics of magnetic iron oxide nanoparticles (MNPs). This study demonstrates that the concentration and morphology of MNPs can influence the polarization of macrophages. The findings have implications for therapeutics targeting tissue regeneration and tumor progression.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2024)
Article
Biochemical Research Methods
Oscar Galarce-Bustos, Camilo Obregon, Alejandro Vallejos-Almirall, Christian Folch, Francisca Acevedo
Summary: This study isolated and identified seven compounds with potential antidiabetic activity from Annona cherimola Mill. leaves using an effect-directed analysis by thin-layer chromatography (TLC)-bioautography. Liriodenine, dicentrinone, N-methylnuciferine, anonaine, moupinamide, 3-methoxybenzenepropanoic acid, and methylferulate showed promising results with inhibitory activity against both enzymes and antioxidant capacity.
PHYTOCHEMICAL ANALYSIS
(2023)
Article
Pharmacology & Pharmacy
Jessica Salvo, Cristian Sandoval, Carolina Schencke, Francisca Acevedo, Mariano del Sol
Summary: This study aimed to investigate the effects of medical-grade honey with copper nanoparticles on the healing of infected or non-infected wounds. The results showed that the selected formulation had the same antibacterial potency as the medical-grade honey alone, and the addition of copper nanoparticles improved the maturation of collagen fibers and regulated the inflammatory process.
Article
Pharmacology & Pharmacy
Claudia Sanhueza, Jeyson Hermosilla, Catherine Klein, Alejandra Chaparro, Ivan Valdivia-Gandur, Victor Beltran, Francisca Acevedo
Summary: Peri-implantitis is a serious condition that can lead to dental implant failure. This study aimed to develop an electrospun scaffold loaded with cholecalciferol to treat peri-implantitis. The scaffold exhibited good mechanical properties and supported cell attachment and proliferation. The cholecalciferol-loaded scaffold promoted bone tissue regeneration. Further studies are needed to confirm the efficacy and safety of the scaffold.
Article
Pharmacology & Pharmacy
Daniela Vergara, Olga Lopez, Claudia Sanhueza, Catalina Chavez-Aravena, Jose Villagra, Mariela Bustamante, Francisca Acevedo
Summary: A novel co-encapsulation system called bicosomes has been developed to overcome the limitations of topical application of curcumin and α-tocopherol. The bicosomes efficiently solubilized and encapsulated curcumin and α-tocopherol, forming homogeneous bicelles. Furthermore, the bicosomes showed significant antioxidant and antifungal effects, making them a promising carrier for antioxidant molecules.
Article
Pharmacology & Pharmacy
Javier Suarez-Gonzalez, Ana Santovena-Estevez, Mabel Soriano, Jose B. Farina
Summary: This study evaluated the quality and stability of a new tablet formulation for treating tuberculosis under different storage conditions. The results showed that tablets stored at low relative humidity exhibited the best stability, and there was no significant difference between tablets exposed to or protected from light. Additionally, no formation of hydrazine, a mutagenic degradation product, was detected. This indicates that the tablet maintains its quality when appropriate storage conditions are used.
PHARMACEUTICAL SCIENCES
(2022)
Review
Biochemistry & Molecular Biology
Rocio Morales-Medina, Stephan Drusch, Francisca Acevedo, Alejandro Castro-Alvarez, Astrid Benie, Denis Poncelet, Marijana M. Dragosavac, Maria Victoria Defain Tesoriero, Patricia Lowenstein, Veronica Yonaha, Ramiro Iturralde, Regina Gauna Peter, Paul de Vos
Summary: Pectins have been proposed as emerging broadly applicable encapsulation materials due to their versatility, cost-effectiveness, and ability to be tailored to specific demands, providing health benefits. Insights into the chemical structure and related health benefits of pectins open new avenues for their application in food and feed. Despite the need for further study on factors such as the controlled release of cargo in the intestine and the impact of the pectin production process on its molecular structure, current knowledge indicates that pectins offer many advantages for encapsulation of bioactive food and feed ingredients.
Article
Biochemistry & Molecular Biology
Wei-Han Hui, Yen-Lin Chen, Shu-Wei Chang
Summary: Crosslinking affects the mechanical behavior and tissue metabolism of collagen-based tissues. Aging and diabetes alter the crosslinking type and density, thus changing tissue properties. High-connectivity enzymatic crosslinking and advanced-glycation end-products result in uniform deformation under daily activity, while low-connectivity enzymatic crosslinking does not. High-connectivity model displays more sliding, while AGEs induce instability in structures near the binding sites.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yao-Bin Ma, Xiao-Qiu Zhou, Wei-Dan Jiang, Pei Wu, Yang Liu, Shu-Wei Li, Ling Tang, Lu Zhang, Hai-Feng Mi, Lin Feng
Summary: Tea polyphenols (TPs) are an inexpensive feed additive that can protect the gill function of fish against Flavobacterium columnare (F. columnare) through various mechanisms, including suppression of oxidative stress, apoptosis, and inflammation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yan-Jia Guo, Jing-Ru Pang, Yu Zhang, Zhong-Rui Li, Xiao-Lin Zi, Hong-Min Liu, Ning Wang, Li-Juan Zhao, Ya Gao, Bo Wang, Piet Herdewijn, Cheng-Yun Jin, Ying Liu, Yi-Chao Zheng
Summary: This study identifies the conjugation of NEDD8 to LSD1 and its impact on GC cells, revealing the significance of LSD1 neddylation in GC.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Geum-Jae Jeong, Fazlurrahman Khan, Nazia Tabassum, Young-Mog Kim
Summary: Vibrio species are motile gram-negative bacteria commonly found in aquatic environments. They can adapt to environmental fluctuations and develop protective mechanisms against host immune systems. Different types of sigma and anti-sigma factors play important roles in regulating gene expression and virulence in Vibrio species.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Zahra Mohammadbagheri, Behrooz Movahedi, Shaghayegh Saeedi, Abbas Rahmati
Summary: In this study, a reusable biobased composite hydrogel was successfully synthesized and used for the removal of Tl(I) from aqueous solutions. The hydrogel exhibited high adsorption capacity and thermal stability, and the adsorption process was found to be thermodynamically spontaneous. The results demonstrated that the hydrogel can be reused multiple times without significant loss of its adsorption capacity.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Iqra Batool, Muhammad Imran, Ayesha Anwar, Farhan Ahmed Khan, Afrah E. Mohammed, Ashwag Shami, Hafiz Iqbal
Summary: Enzyme immobilization on ZnO/SnO2 and ZnO/SnO2/SA nanocomposites was studied, and the catalytic and biochemical characteristics of the immobilized enzyme were investigated. The results showed that ZnO/SnO2 and ZnO/SnO2/SA nanostructures are suitable carriers for enzyme immobilization.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Elias Mosaffa, Dhruvi Patel, Nasim Amiri Ramsheh, Rishikumar Indravadan Patel, Atanu Banerjee, Hossein Ghafuri
Summary: In this study, a unique 3D bead structure of adsorbent, composed of bacterial cellulose microfilaments reinforced chitosan adorned with melamine 2D plates, was synthesized for anionic dye removal. The adsorbent showed high specific surface area and abundant functional groups, resulting in exceptional adsorption capacity. The characteristics and optimal conditions of the adsorbent were assessed and analyzed.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Carolina Gismene, Jorge Enrique Hernandez Gonzalez, Marilia de Freitas Calmon, Andrey Fabricio Ziem Nascimento, Angela Rocio Nino Santisteban, Felipe Antunes Calil, Alana Della Torre da Silva, Paula Rahal, Rejane Maira Goes, Raghuvir Krishnaswamy Arni, Ricardo Barros Mariutti
Summary: Mammaliicoccus sciuri, a bacterium of clinical and veterinary relevance, expresses the virulence factor Exfoliative Toxin C (ExhC), which binds specifically to desmoglein-1 (Dsg1) and plays a role in tissue integrity. This study investigates the necrotic activity of ExhC and identifies a variant lacking necrotic potential but retaining enzymatic activity through mutagenesis experiments and crystal structure determination.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Bibhas K. Bhunia, Ashutosh Bandyopadhyay, Souradeep Dey, Biman B. Mandal
Summary: Intervertebral disc degeneration is a major cause of chronic low back pain and disability. Researchers have developed a bioactive silk-based hybrid hydrogel system functionalized with decellularized human Wharton's jelly extracellular matrix as bioactive cues. The hydrogels mimic the rheological and mechanical properties of the native nucleus pulposus tissue and support cell viability, proliferation, and tissue maturation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Qun Zhang, Yonggan Yan, Zhao Li, Jing Du, Kai Zhang, Liguo Zhang, Ting Wang, Alberto Bianco, Shaohua Ge, Baojin Ma
Summary: A new crosslinking strategy has been devised to construct injectable sodium alginate hydrogels, which can be regulated for injectability and have great potential in biomedical applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Seong Eun Hong, Ji-Soo Lee, Hyeon Gyu Lee
Summary: The potential of multi-layer nanoemulsions for improving the cellular uptake, antioxidant activity, and in vitro bioaccessibility of alpha-tocopherol was examined. The results showed that the multi-layer nanoemulsions significantly enhanced the cellular uptake and antioxidant activity of alpha-tocopherol compared to free coumarin 6. Furthermore, the use of chitosan and dextran sulfate as wall materials in the multi-layer nanoemulsions led to even higher cellular uptake, in vitro bioaccessibility, and antioxidant activity of alpha-tocopherol.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jingjing Yu, Yanhui Zhang, Ruoning Zhang, Yanxiang Gao, Like Mao
Summary: High internal phase emulsions (HIPEs) based on beeswax (BW) oleogels and octenyl succinic acid starch (OSA starch) were prepared by a simple one-step method. The results showed that oleogelation improved the stability and encapsulation capability of the HIPEs, which is significant for the development of novel healthy food.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Bi-Feng Yao, Xiu-Ju Luo, Jun Peng
Summary: The balanced and continuous fission and fusion of mitochondria, regulated by OPA1, are important for maintaining mitochondrial dynamics in cardiovascular disorders. Understanding the role of OPA1 in mitochondrial fusion can provide insights into the pathogenesis of cardiovascular diseases.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Gokul Paramasivam, Anandhavelu Sanmugam, Vishnu Vardhan Palem, Murugan Sevanan, Ananda Babu Sairam, Nachiappan Nachiappan, Buhyun Youn, Jung Sub Lee, Muthuchamy Nallal, Kang Hyun Park
Summary: Nanomaterials are being used to deliver therapeutic agents in living systems. Different nanotechnological applications such as immunosensors, immune assays, and drug delivery are being implemented using nanotechnology. Genomics plays a crucial role in selecting appropriate drugs for personalized cancer therapy. It helps in analyzing gene and protein expression, disease classification, and designing disease models. Delivering drugs to specific areas using nanoparticles is a challenging issue.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jing Li, Wei Wang, Han Wu, Feng Peng, Hui Gao, Ying Guan
Summary: In this study, CMH-based CPF films were prepared and their thermal and barrier properties were successfully regulated. The tensile strength and water vapor barrier property of CPF films were significantly improved, making them promising for food packaging applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
