Article
Gastroenterology & Hepatology
Anne F. Peery, Aasma Shaukat, Lisa L. Strate
Summary: Management of colonic diverticulitis should involve personalized diagnosis and treatment based on the patient's condition, including the use of imaging and lower endoscopy to exclude alternative diagnoses, selective antibiotic use, and lifestyle modifications to reduce the risk of recurrence. Patients should understand the importance of diet and healthy behaviors in preventing future episodes of diverticulitis.
Review
Gastroenterology & Hepatology
Peter H. R. Green, Shirley Paski, Cynthia W. Ko, Alberto Rubio-Tapia
Summary: This article summarizes the diagnosis and management of refractory celiac disease, providing guidance on evaluation, nutritional support, potential therapeutic options, and surveillance for complications. The article emphasizes the importance of regular follow-up and multidisciplinary care for patients with refractory celiac disease.
Review
Gastroenterology & Hepatology
Peter S. Liang, Aasma Shaukat, Seth D. Crockett
Summary: This expert review provides best practice advice for the chemoprevention of colorectal neoplasia, recommending the use of low-dose aspirin, metformin, and advising against the use of non-aspirin NSAIDs, calcium, vitamin D for prevention.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2021)
Article
Gastroenterology & Hepatology
Laura E. Targownik, Deborah A. Fisher, Sameer D. Saini
Summary: Proton pump inhibitors (PPIs) are widely used medications, but over prescription can lead to economic costs and adverse events. Deprescribing PPIs in ambulatory patients is an important strategy to reduce pill burden and costs. This clinical update provides best practice advice on PPI deprescribing.
Review
Gastroenterology & Hepatology
Puneeta Tandon, Anne Walling, Heather Patton, Tamar Taddei
Summary: Palliative Care is an approach focusing on improving the quality of life for patients facing life-limiting illness, applicable in cirrhosis patients. However, there is limited guidance and promotion of PC in patients with cirrhosis.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2021)
Review
Gastroenterology & Hepatology
Brian E. Lacy, Jan Tack, C. Prakash Gyawali
Summary: This article outlines a strategy for defining, diagnosing, and managing refractory gastroparesis, including evaluating symptoms and physical examination findings, verifying the accuracy of gastric emptying studies, classifying patients based on symptoms and study results, and initiating treatment based on the predominant symptom.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2022)
Review
Gastroenterology & Hepatology
Maureen M. Leonard, Benjamin Lebwohl, Alberto Rubio-Tapia, Federico Biagi
Summary: This study provides consensus statements on the diagnosis and management of patients with suspected celiac disease but negative results from serologic tests. Recommendations include reviewing histologic findings, conducting serologic tests, analyzing patient diets, collecting medication histories, and genetic testing to aid in accurate diagnosis and management.
Review
Gastroenterology & Hepatology
Bruce Wang, Herbert L. Bonkovsky, Joseph K. Lim, Manisha Balwani
Summary: Acute hepatic porphyrias (AHP) are rare, inborn errors of heme-metabolism. The most common type is acute intermittent porphyria. It mainly affects women of childbearing age and presents with severe abdominal pain. Diagnosis can be confirmed through urine tests, and management involves discontinuation of triggering drugs, administration of glucose and hemin, and use of painkillers and antiemetics.
Review
Gastroenterology & Hepatology
Shailja C. Shah, Prasad G. Iyer, Steven F. Moss
Summary: The purpose of this CPU Expert Review is to provide clinicians with guidance on the management of Helicobacter pylori after initial eradication therapy failure. The review is not formal systematic, but based on literature to provide practical advice. The strength or quality of the evidence was not formally rated, instead a combination of available evidence and consensus-based expert opinion were used to develop best practice advice.
Review
Gastroenterology & Hepatology
William D. Chey, Jana G. Hashash, Laura Manning, Lin Chang
Summary: Irritable bowel syndrome (IBS) is a common gastrointestinal disorder that affects quality of life. The latest clinical practice update recommends dietary modifications, such as the low-FODMAP diet, as the primary treatment for IBS symptoms. Best practice advice includes involving patients who are insightful and motivated in dietary changes, avoiding restrictive diets for patients who are poor candidates, highlighting the benefits of soluble fiber and the low-FODMAP diet, and following a three-phase approach for the low-FODMAP diet. The efficacy of a gluten-free diet for IBS is uncertain and there is limited evidence to support the routine use of biomarkers in clinical practice.
Review
Gastroenterology & Hepatology
David C. Whitcomb, Anna M. Buchner, Chris E. Forsmark
Summary: Exocrine pancreatic insufficiency (EPI) is a disorder caused by the failure of the pancreas to deliver enough digestive enzymes to the intestine, leading to malabsorption of nutrients. It is often underdiagnosed and requires increased awareness and treatment. Best practice advice for EPI includes treatment with pancreatic enzyme replacement therapy, monitoring of nutritional status, and supplementation as needed.
Review
Gastroenterology & Hepatology
Baha Moshiree, Douglas Drossman, Aasma Shaukat
Summary: Belching, bloating, and abdominal distention are common gastrointestinal symptoms that significantly affect patients' quality of life. This article provides best practice advice for clinicians on how to differentiate, diagnose, and manage these symptoms using dietary, behavioral, and drug therapies. The importance of proper evaluation and testing to rule out other potential diseases is also emphasized.
Review
Gastroenterology & Hepatology
Daniel S. Strand, Ryan J. Law, Dennis Yang, B. Joseph Elmunzer
Summary: The purpose of this study is to provide practical and evidence-based guidance on the role of endoscopy in recurrent acute and chronic pancreatitis, and ensure its accuracy and reliability through peer review.
Review
Gastroenterology & Hepatology
Rajesh N. Keswani, Seth D. Crockett, Audrey H. Calderwood
Summary: The purpose of this study was to provide best practice advice on improving the quality of screening and surveillance colonoscopy, but no formal rating of evidence quality or strength of recommendation was conducted.
Review
Gastroenterology & Hepatology
Rachel B. Issaka, Andrew T. Chan, Samir Gupta
Summary: Despite the decline in CRC mortality, it remains the second leading cause of cancer deaths in the United States. The AGA provides risk-stratification guidelines for CRC screening and post-polypectomy surveillance, while also calling for future research to fill gaps in the existing literature.
Article
Multidisciplinary Sciences
Gabriela Leite, Walter Morales, Stacy Weitsman, Shreya Celly, Gonzalo Parodi, Ruchi Mathur, Gillian M. Barlow, Rashin Sedighi, Maria Jesus Villanueva Millan, Ali Rezaie, Mark Pimentel
Article
Multidisciplinary Sciences
Ali Rezaie, Gabriela G. S. Leite, Gil Y. Melmed, Ruchi Mathur, Maria Jesus Villanueva-Millan, Gonzalo Parodi, Jon Sin, Juliana F. Germano, Walter Morales, Stacy Weitsman, Seung Young Kim, Jae Ho Park, Siamak Sakhaie, Mark Pimentel
Review
Psychiatry
Will Takakura, Mark Pimentel
FRONTIERS IN PSYCHIATRY
(2020)
Article
Gastroenterology & Hepatology
Brian E. Lacy, Mark Pimentel, Darren M. Brenner, William D. Chey, Laurie A. Keefer, Millie D. Long, Baha Moshiree
Summary: Irritable bowel syndrome (IBS) is a chronic disorder that significantly impacts patients' quality of life. The American College of Gastroenterology has developed a clinical guideline using GRADE methodology for the management of IBS, recommending a positive diagnostic approach, specific tests, treatments, and gut-directed psychotherapy to improve symptoms for patients with IBS.
AMERICAN JOURNAL OF GASTROENTEROLOGY
(2021)
Article
Rheumatology
Yossra Suliman, Suzanne Kafaja, Sunny J. Oh, Mohamed Alemam, Gianluca Bagnato, Giuseppina Abignano, Ram Raj Singh, Gillian Barlow, Xiaochen Liu, Isela Valera, Walter Morales, Ali Rezaie, Mark Pimentel, Francesco Del Galdo, Daniel E. Furst
Summary: The study shows that elevated anti-vinculin antibody levels are common in patients with SSc and suggests a potential link between increased anti-vinculin levels and gastrointestinal symptoms.
CLINICAL RHEUMATOLOGY
(2021)
Article
Gastroenterology & Hepatology
Stacy Weitsman, Shreya Celly, Gabriela Leite, Ruchi Mathur, Rashin Sedighi, Gillian M. Barlow, Walter Morales, Maritza Sanchez, Gonzalo Parodi, Maria Jesus Villanueva-Millan, Ali Rezaie, Mark Pimentel
Summary: This study compared the duodenal and stool microbiomes of PPI users and non-users, finding differences in the relative abundance of certain microbial families in the duodenal and stool microbiomes of PPI users. However, PPI use was not associated with higher rates of SIBO. The clinical implications of these findings remain unclear.
DIGESTIVE DISEASES AND SCIENCES
(2022)
Meeting Abstract
Gastroenterology & Hepatology
Leopoldo Valiente-Banuet, Gabriela Leite, Ruchi Mathur, Mark Pimentel
AMERICAN JOURNAL OF GASTROENTEROLOGY
(2020)
Meeting Abstract
Gastroenterology & Hepatology
Will Takakura, Christine Chang, Ava Hosseini, Jiajing Wang, Edward Kowalewski, Ruchi Mathur, Ali Rezaie, Mark Pimentel
AMERICAN JOURNAL OF GASTROENTEROLOGY
(2020)
Meeting Abstract
Gastroenterology & Hepatology
Shreya Celly, Gabriela Leite, Gillian Barlow, Gonzalo Parodi, Maritza Sanchez, Maria Jesus Villanueva-Millan, Rashin Sedighi, Mark Pimentel, Ruchi Mathur
Meeting Abstract
Gastroenterology & Hepatology
Shreya Celly, Rashin Sedighi, Gabriela Leite, Maria Jesus Villanueva-Millan, Maritza Sanchez, Gonzalo Parodi, Mark Pimentel, Ali Rezaie, Ruchi Mathur
Meeting Abstract
Gastroenterology & Hepatology
Christine Chang, Ava Hosseini, Rashin Sedighi, Gabriela Leite, Ali Rezaie, Mark Pimentel, Ruchi Mathur
Meeting Abstract
Gastroenterology & Hepatology
Christopher Chang, William D. Chey, Mark Pimentel, Zeev Heimanson, Brian E. Lacy
Meeting Abstract
Gastroenterology & Hepatology
Chandrima Chatterjee, Rashin Sedighi, Gabriela Leite, Shreya Celly, Ava Hosseini, Ali Rezaie, Mark Pimentel, Ruchi Mathur
Meeting Abstract
Economics
C. Tyson, M. Pimentel, R. Magar