Article
Peripheral Vascular Disease
Dan Liao, Zhi-Peng Guo, Li-Rong Tang, Yue Gao, Zhu-Qing Zhang, Ming-Hao Yang, Rong-Ping Wang, Chun-Hong Liu
Summary: Our study aims to investigate the alterations and diagnostic efficiency of regional homogeneity (ReHo) and functional connectivity (FC) in hypertension patients with cognitive impairment. We enrolled 62 hypertension patients with cognitive impairment (HTN-CI), 59 hypertension patients with normal cognition (HTN-NC), and 58 healthy controls (HCs) with rs-fMRI data. Univariate analysis was performed to observe brain regions with significant differences among the three groups. MVPA analysis displayed high classification ability in distinguishing HTN-CI from HTN-NC and HCs. The findings may contribute to unveiling the underlying neuropathological mechanism of HTN-CI.
HYPERTENSION RESEARCH
(2023)
Article
Dentistry, Oral Surgery & Medicine
Lewis Winning, Celine De Looze, Silvin P. Knight, Daniel Carey, James F. Meaney, Rose Anne Kenny, Brian O'Connell
Summary: Tooth loss is associated with regional grey matter volume (GMV) in community dwelling older men and women from Ireland. Participants with 1-19 teeth and >20 teeth showed increased GMV in the paracentral lobule and cuneus cortex compared to edentates. This finding may provide a potential explanatory link to the association between tooth loss and cognitive decline.
JOURNAL OF DENTISTRY
(2023)
Article
Behavioral Sciences
Luyi Zhou, Yihang Ma, Hong Chen, Pengfei Han
Summary: Both food cravings and long-term food consumption have different effects on the brain, and these effects show sex differences. This study aimed to explore the potential sex-specific neuroanatomical correlations between spicy food craving and habitual spicy food consumption. The results showed that in women, spicy food craving was significantly correlated with gray matter volume in the right supplementary motor area (SMA) and the dorsal superior frontal gyrus, while in men, it was associated with greater gray matter volume in the inferior temporal gyrus and the occipital gyrus. In addition, habitual spicy food consumption was correlated with increased gray matter volume in the bilateral putamen, left postcentral gyrus, and right paracentral lobule, which was more pronounced in female participants. These findings suggest that there are distinct central neural reflections of trait craving or habitual exposure to spicy flavors, and the sex-specific correlation between spicy food craving and brain anatomical features may be related to food-related sensory imagery or cognitive control.
Article
Clinical Neurology
Bochao Cheng, Xiao Hu, Neil Roberts, Yajun Zhao, Xin Xu, Yushan Zhou, Xi Tan, Shanhui Chen, Yajing Meng, Song Wang, Haoyang Xing, Wei Deng
Summary: This structural MRI study analyzed the differences in neural structures between postpartum depression (PPD) patients and healthy postnatal women (HPW), as well as the relationship with a range of factors. The results showed significant differences in regional gray matter volume (rGMV) and prolactin levels between PPD patients and HPW. Prolactin level was found to mediate the relationship between brain structure and PPD symptoms in the anterior insular region.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Behavioral Sciences
Chen Bai, Yunlei Wang, Yan Zhang, Xianna Wang, Zhenbo Chen, Weiyong Yu, Haojie Zhang, Xingzhu Li, Kaixuan Zhu, Yuxiang Wang, Tong Zhang
Summary: This study used structural and functional magnetic resonance imaging (MRI) to investigate brain abnormalities in young children with Autism Spectrum Disorder (ASD). The results showed that children with ASD had increased gray matter volumes in social cognition-related brain regions compared to typically developing controls. Additionally, the functional connectivity in certain brain regions was correlated with adaptability and language development in children with ASD. The combination of structural and functional features had high accuracy in discriminating between ASD and typically developing children.
Article
Neurosciences
Wenjing Zhu, Zan Wang, Miao Yu, Xiangrong Zhang, Zhijun Zhang
Summary: Deficient schizophrenia (DS) and non-deficient schizophrenia (NDS) have differences in functional connectivity (FC) based on region of interest (ROI) from gray matter volume (GMV). This study investigates FC alterations between DS and NDS and their correlation with clinical symptoms. Thalamic functional connection imbalance is also explored.
FRONTIERS IN NEUROSCIENCE
(2023)
Article
Neurosciences
Kelly Rootes-Murdy, Elaheh Zendehrouh, Vince D. Calhoun, Jessica A. Turner
Summary: Individuals with schizophrenia exhibit consistent gray matter reductions in regions such as the prefrontal cortex, cerebellum, and thalamus. Both univariate and multivariate analyses showed that healthy controls had higher gray matter volume and concentration compared to patients. While there was moderate overlap between different gray matter quantities, only a few brain regions showed significant correlations in patterns across the cortex.
FRONTIERS IN NEUROSCIENCE
(2021)
Article
Medicine, General & Internal
Deokjong Lee, Woojin Kim, Jung Eun Lee, Junghan Lee, Seung-Koo Lee, Sei-Jin Chang, Da Yee Jeung, Dae-Sung Hyun, Hye-Yoon Ryu, Changsoo Kim, Young-Chul Jung
Summary: The study revealed that firefighters with high occupational stress exhibited lower gray matter volume in regions such as the insula, left amygdala, right medial prefrontal cortex, and anterior cingulate cortex. These gray matter abnormalities are associated with emotional dysregulation and may contribute to firefighter susceptibility to burnout.
JOURNAL OF KOREAN MEDICAL SCIENCE
(2021)
Article
Multidisciplinary Sciences
Elisabeth Solana, Eloy Martinez-Heras, Victor Montal, Eduard Vilaplana, Elisabet Lopez-Soley, Joaquim Radua, Nuria Sola-Valls, Carmen Montejo, Yolanda Blanco, Irene Pulido-Valdeolivas, Maria Sepulveda, Magi Andorra, Joan Berenguer, Pablo Villoslada, E. H. Martinez-Lapiscina, Ferran Prados, Albert Saiz, Juan Fortea, Sara Llufriu
Summary: In multiple sclerosis, the diffusion rate and volume changes of gray matter show differential spatial predominance in different brain regions as the disease progresses. Furthermore, microstructural integrity loss and atrophy at different stages are associated with white matter lesion load and physical and cognitive disability.
SCIENTIFIC REPORTS
(2021)
Article
Neurosciences
Xia Zhe, Xiaoling Zhang, Li Chen, Li Zhang, Min Tang, Dongsheng Zhang, Longchao Li, Xiaoyan Lei, Chenwang Jin
Summary: This study found that patients with vestibular migraine show structural alterations in areas associated with pain and vestibular processing, as well as changes in resting-state functional connectivity in these regions. Reduced gray matter volume in the left parietoinsular vestibular cortex was negatively correlated with Dizziness Handicap Inventory score in patients, and increased functional connectivity was observed between the left primary somatosensory cortex/inferior parietal lobule and the left PIVC in patients with vestibular migraine.
FRONTIERS IN NEUROSCIENCE
(2021)
Article
Psychology, Clinical
Beatrix Krause-Sorio, Prabha Siddarth, Michaela M. Milillo, Lisa A. Kilpatrick, Katherine L. Narr, Helen Lavretsky
Summary: This study examined the relationships between geriatric depression, brain morphometry, anxiety, and resilience. The results showed that greater gray matter volume in widespread brain regions was associated with reduced anxiety and apathy, as well as increased resilience.
INTERNATIONAL PSYCHOGERIATRICS
(2023)
Article
Geriatrics & Gerontology
Min Zhong, Chenglin Li, Hongquan Lu, Donghui Xue, Yaxi Wang, Yinyin Jiang, Sha Zhu, Ruxin Gu, Xu Jiang, Bo Shen, Jun Zhu, Wenbin Zhang, Yang Pan, Jun Yan, Li Zhang
Summary: This study aims to investigate the pathogenesis of minor hallucination in Parkinson's disease and identify brain regions associated with structural and functional abnormalities that may contribute to the generation of hallucinations in PD.
FRONTIERS IN AGING NEUROSCIENCE
(2022)
Article
Psychiatry
Zhenning Ding, Zhipeng Ding, Yunhui Chen, Dan Lv, Tong Li, Tinghuizi Shang, Jidong Ma, Chuang Zhan, Xu Yang, Jian Xiao, Zhenghai Sun, Na Wang, Wenbin Guo, Chengchong Li, Zengyan Yu, Ping Li
Summary: Previous studies have found abnormal structures and functions in the brains of OCD patients. However, it is still unclear whether structural changes in the brain regions are related to alterations in dynamic functional connectivity in medicine-free OCD patients at rest. This study compared the gray matter volume differences between 50 medicine-free OCD patients and 50 healthy controls using MRI, and found reduced gray matter volume in the left superior temporal gyrus and right supplementary motor area in OCD patients, along with decreased dynamic functional connectivity in these brain regions. Finally, the study showed that the altered multimodal imaging data could accurately distinguish OCD patients from healthy controls with a high sensitivity and specificity.
Article
Clinical Neurology
Peirong Wu, Xiaomin Pang, Xiulin Liang, Wutong Wei, Xinrong Li, Jingyuan Zhao, Jinou Zheng
Summary: Our study reveals abnormal cerebral function in anti-NMDAR encephalitis patients, related to executive dysfunction. Patients show reduced ReHo values in multiple brain regions, with the bilateral posterior cerebellar lobe, anterior cerebellar lobe, midbrain, bilateral caudate nucleus, right superior frontal gyrus, right middle temporal gyrus, bilateral inferior parietal lobule, and left middle frontal gyrus being particularly affected. Furthermore, the ReHo values in the bilateral inferior parietal lobule were negatively associated with executive control scores in patients.
EUROPEAN JOURNAL OF NEUROLOGY
(2022)
Article
Anatomy & Morphology
Ayaka Ando, Peter Parzer, Michael Kaess, Susanne Schell, Romy Henze, Stefan Delorme, Bram Stieltjes, Franz Resch, Romuald Brunner, Julian Koenig
Summary: By longitudinally tracking structural brain development during adolescence, this study found that age best predicted longitudinal changes, while pubertal status had a significant impact on certain brain regions. However, the major limitation of this study was the recruitment of only two cohorts, limiting the investigation of complete trajectories over 6 years of development. Further longitudinal studies in more diverse samples are needed to replicate these findings and explore mechanisms underlying norm-variants in brain development.
BRAIN STRUCTURE & FUNCTION
(2021)
Correction
Computer Science, Interdisciplinary Applications
Xi Zhang, Xianhai Wang, Hongke Zhao, Patricia Ordonez de Pablos, Yongqiang Sun, Hui Xiong
Article
Biochemistry & Molecular Biology
Feng Liu, Jiayuan Xu, Lining Guo, Wen Qin, Meng Liang, Gunter Schumann, Chunshui Yu
Summary: Individual differences in human brain structure, function, and behavior can be explained by genetic variations, environmental exposures, and their interactions. While genetic variants associated with brain imaging phenotypes have been identified, the environmental exposures related to these phenotypes are largely unknown. This study proposes that research in environmental neuroscience should focus on understanding the associations between lifetime environmental exposures and brain imaging phenotypes, as well as identifying cumulative environmental effects and their vulnerable age windows.
MOLECULAR PSYCHIATRY
(2023)
Article
Neurosciences
Jingchun Liu, Caihong Wang, Wen Qin, Hao Ding, Yanmin Peng, Jun Guo, Tong Han, Jingliang Cheng, Chunshui Yu
Summary: Subcortical ischemic stroke can cause long-lasting changes in the cerebral cortex. This study investigated the relationship between cortical structural changes, motor recovery, lesion location, and early impairment of specific subsets of fibers in the corticospinal tract (CST) in patients with subcortical stroke. The findings revealed different patterns of cortical structural changes in patients with partial and complete recovery, which were associated with lesion location and impairment of specific CST fiber subsets.
HUMAN BRAIN MAPPING
(2023)
Article
Business
Xi Zhang, Yihang Cheng, Juan Liu, Hongke Zhao, Dongming Xu, Yulong Li
Summary: This study investigates the mechanism of lender retention in online prosocial lending from a self-determination perspective. The findings suggest that the lender's lending experience, such as the use of profit language in loan narratives and past participation failure, negatively affect lender retention. On the other hand, the lender's social connections, such as having friends or being part of a small lending team, positively influence lender retention. The study contributes to the literature on online philanthropy, self-determination theory, and user retention on online platforms.
Article
Business
Xi Zhang, Xuyan Wang, Fangqing Tian, Dongming Xu, Longwei Fan
Summary: This paper examines the impact of individual learning goal orientation and the digital feedback environment on individuals' feedback-seeking behaviors, and investigates the moderating effect of time pressure on these relationships.
Article
Neurosciences
Huaigui Liu, Wei Li, Nana Liu, Jie Tang, Lixin Sun, Jiayuan Xu, Yuan Ji, Yingying Xie, Hao Ding, Zhaoxiang Ye, Chunshui Yu, Wen Qin
Summary: Evidence suggests that dysregulation of the dopamine (DA) system and dysfunction of the prefrontal cortex (PFC) may contribute to the development of schizophrenia. However, the relationship between DA genes, PFC morphology, and schizophrenia is still not fully understood. In this study, we analyzed brain gene expression data and structural magnetic resonance imaging data to identify specific PFC subregions that are associated with the expression profiles of DA genes. We found that some PFC subregions showed abnormal increases in gray matter volume covariance with other brain regions in schizophrenia patients. Furthermore, our analysis of postmortem expression data revealed reduced coexpression of DA genes between the middle frontal gyrus and hippocampus in schizophrenia patients, with these genes being implicated in brain functions related to working memory, reward processing, speech production, and episodic memory.
Article
Neurosciences
Wenshuang Zhu, Feng Liu, Jilian Fu, Wen Qin, Kaizhong Xue, Jie Tang, Yong Zhang, Chunshui Yu
Summary: This study identified 903 clinically sensitive genes and 633 clinically insensitive genes associated with ALFF alterations in MDD. The sensitive genes were enriched for cell differentiation and development, while the insensitive genes were enriched for ion transport and synaptic signaling.
CNS NEUROSCIENCE & THERAPEUTICS
(2023)
Article
Endocrinology & Metabolism
Jingchun Liu, Caihong Wang, Wen Qin, Jun Guo, Tong Han, Jingliang Cheng, Chunshui Yu
Summary: Subcortical stroke leads to structural changes in multiple areas of the cerebral cortex. The location of the lesion affects the pattern of cortical thickness changes. Motor outcomes and impairment of the corticospinal tract are correlated with cortical thickness in specific gyri. The longitudinal dataset shows gradual changes in cortical thickness and area in regions with structural reorganization.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
(2023)
Article
Neuroimaging
Ling Wang, Yi Ji, Hao Ding, Qin Tian, Ke Fan, Dapeng Shi, Chunshui Yu, Wen Qin
Summary: The study used arterial spin labeling (ASL) to investigate abnormal cerebral blood flow (CBF) in patients with Leber's hereditary optic neuropathy (LHON) and its associations with disease duration and neuro-ophthalmological impairment. The results showed differences in brain regions of LHON patients, including the left sensorimotor and bilateral visual areas. LHON patients had lower CBF in the bilateral calcarine compared to healthy controls. Chronic LHON patients also showed lower CBF in the left middle frontal gyrus, sensorimotor cortex, and temporal-partial junction. Disease duration and neuro-ophthalmological impairments were found to affect the metabolism of non-visual areas.
BRAIN IMAGING AND BEHAVIOR
(2023)
Article
Management
Xi Zhang, Rui Chang, Minhao Gu, Baofeng Huo
Summary: This paper examines the impact of blockchain implementation on shareholder value by analyzing 138 blockchain implementation announcements of companies listed on the Chinese A-share stock market. The results show that blockchain implementation has a positive effect on shareholder value, which is moderated by business diversification, supply chain concentration, and environmental complexity.
INTERNATIONAL JOURNAL OF OPERATIONS & PRODUCTION MANAGEMENT
(2023)
Article
Computer Science, Information Systems
Dazhong Shen, Hengshu Zhu, Keli Xiao, Xi Zhang, Hui Xiong
Summary: In this article, a data-driven joint Bayesian learning approach called Joint-PJB is introduced to discover explainable joint patterns from personality and job-position-related behavioral data. The model is found to effectively measure the matching degree between employees and their work behaviors, and it showcases its utility in real-world talent management decisions.
ACM TRANSACTIONS ON MANAGEMENT INFORMATION SYSTEMS
(2023)
Article
Business
Xi Zhang, Xiaopei Liu, Yi Zhang, Bo Jin
Summary: Video course previews provide direct product experience for customers, reducing information asymmetry and promoting purchases. This study examines the interaction effects between extrinsic cues and video course previews and explores the effects of intrinsic cues based on cue utilization theory. Empirical testing using data from a medical knowledge payment platform reveals interesting findings with direct implications for optimizing previews and understanding the influence mechanism of video course previews on knowledge payment platforms.
IEEE TRANSACTIONS ON ENGINEERING MANAGEMENT
(2023)