Article
Fisheries
Chunling Wang, Jingyu Pan, Xiaodan Wang, Xinyu Cai, Zhideng Lin, Qingchao Shi, Erchao Li, Jian G. Qin, Liqiao Chen
Summary: The research showed that dietary N-acetylcysteine (NAC) improved growth performance and survival of Chinese mitten crab fed T-2 toxin. A dosage of 0.1% NAC effectively alleviated oxidative stress, immunodepression, and apoptosis induced by T-2 toxin.
Article
Fisheries
Kun Guo, Zhigang Zhao, Liang Luo, Shihui Wang, Rui Zhang, Wei Xu, Guo Qiao
Summary: This study found that aerial exposure stress affects oxidative damage and antioxidant capacity in the hepatopancreas of Eriocheir sinensis; immune-related enzyme activity and intestinal microbiota composition are also altered.
Article
Biochemistry & Molecular Biology
Xinping Guo, Ziang Qian, Qiqi Pan, Yuqing Hu, Wangxin Mei, Xiumei Xing, Shaowu Yin, Jie Ji, Kai Zhang
Summary: Excessive use of antibiotics in aquaculture leads to antibiotic residues in aquatic animal products, which poses a threat to human health. This study investigated the effects of florfenicol (FF) on Chinese mitten crabs, focusing on gut health, microbiota, and their relationship. The results showed that FF exposure caused significant changes in gut morphology, immune responses, apoptosis characteristics, and antioxidant enzyme activities. The high concentration of FF also led to a decrease in microbial diversity and changes in composition. These findings provide new insights into the impact of antibiotics on gut health and microbiota in aquatic invertebrates.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Environmental Sciences
Yuhang Hong, Yi Huang, Yanzhen Dong, Dayong Xu, Qiang Huang, Zhiqiu Huang
Summary: This study investigated the cytotoxic effects of abamectin on hepatopancreas cells of Chinese mitten crab. The results showed that abamectin inhibited cell viability and caused oxidative stress, DNA damage, and apoptosis. It also induced changes in antioxidant response and immune status.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2023)
Article
Marine & Freshwater Biology
Su Jiang, Weijian Zhang, Xiaobin Qian, Jie Ji, Xianhui Ning, Fei Zhu, Shaowu Yin, Kai Zhang
Summary: Hypoxia has irreversible damage on aquatic animals, but there are few reports on the effects of hypoxia stress and reoxygenation on intestinal homeostatic imbalance and consequent hepatopancreas-intestine axis health in crustacean. In this study, Chinese mitten crabs were exposed to hypoxic stress for 96 hours and then reoxygenated for 96 hours. The results showed that hypoxia impaired the intestinal tissue structure, increased oxidative stress, and altered the composition of the gut microbiota.
AQUATIC TOXICOLOGY
(2023)
Article
Fisheries
Zhiqiang Li, Zhigang Zhao, Liang Luo, Shihui Wang, Rui Zhang, Kun Guo, Yuhong Yang
Summary: This study investigated the effects of heat stress on the immune function, metabolism, and intestinal microbiota of Chinese mitten crab. The results showed that heat stress significantly affected the immune function and composition of the intestinal microbiota in this species.
Article
Environmental Sciences
Xingyu Nan, Xingkun Jin, Yu Song, Kaimin Zhou, Yukai Qin, Qun Wang, Weiwei Li
Summary: Using Chinese mitten crabs as a model, this study investigated the effects of polystyrene nanoplastics (PS NPs) on cell apoptosis, glucose metabolism, and antibacterial immunity. The results showed that PS NPs were endocytosed by crab hemocytes, leading to abnormal cell apoptosis, glucose metabolism disorder, and changes in antimicrobial immunity.
ENVIRONMENTAL POLLUTION
(2022)
Article
Fisheries
Xiawei Yu, Wenbin Liu, Keke Chen, Yuan Liu, Ying Deng, Cheng Chi
Summary: This study evaluated the effects of LBP on the hepatopancreas of Chinese mitten crab and found that LBP could restore the damage caused by T-2 toxin, improve antioxidant capacity, and reduce apoptosis and inflammation.
AQUACULTURE REPORTS
(2023)
Article
Biochemistry & Molecular Biology
Peng Huang, Liping Cao, Jinliang Du, Jiancao Gao, Yuning Zhang, Yi Sun, Quanjie Li, Zhijuan Nie, Gangchun Xu
Summary: There is growing evidence that long-term exposure to the widely used herbicide prometryn can induce toxicity in bony fish and shrimp. This study investigated the effects of prometryn on the hepatopancreas and intestine of the crab Eriocheir sinensis through a 20-day exposure experiment. The findings suggest that prometryn can reduce antioxidant enzyme activities, increase lipid peroxidation levels, and cause oxidative stress.
Article
Environmental Sciences
Xiaowen Zhang, Manli Shen, Cui Wang, Miaomiao Gao, Liuen Wang, Zeyu Jin, Xiaohua Xia
Summary: This study evaluated the effects of aluminum exposure on crayfish. The results showed that aluminum induced biochemical, histological, gut microbial, and immune changes in the crayfish. Therefore, excessive aluminum exposure may have adverse effects on various biological processes of crayfish, posing a potential threat to crayfish culture.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Fisheries
Ruoyu Zhou, Jinsong Liu, Xueyan Shi, Chunsheng Fu, Ying Jiang, Ruiqiang Zhang, Yanping Wu, Caimei Yang
Summary: This study demonstrated that the addition of garlic powder has positive effects on the growth performance, nonspecific immunity, antioxidant capacity, and intestinal flora structure of Chinese mitten crabs.
AQUACULTURE NUTRITION
(2022)
Article
Pharmacology & Pharmacy
Xiaozhen Yang, Xiaowen Yu, Ningbo Sun, Xingliang Shi, Chao Niu, Aoya Shi, Yongxu Cheng
Summary: The study revealed that GBH adversely affects the testes morphology and physiological functions of Chinese mitten crab, potentially causing decreases through inducing oxidative damage and apoptosis pathways. Additionally, the quality of spermatozoa was significantly impacted, thereby affecting the reproductive system.
TOXICOLOGY AND APPLIED PHARMACOLOGY
(2022)
Article
Environmental Sciences
Peng Huang, Jinliang Du, Liping Cao, Jiancao Gao, Quanjie Li, Yi Sun, Nailin Shao, Yuning Zhang, Gangchun Xu
Summary: In this study, the toxic effects of the triazine pesticide prometryn on Eriocheir sinensis were evaluated. The results showed that prometryn can cause damage to the hepatopancreas of E. sinensis through oxidative stress, induction of cell apoptosis, disruption of lipid metabolism, and immune damage.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2023)
Article
Fisheries
Tong Li, Demin Zhang, Yunfei Sun, Xiaozhen Yang, Wenwen Xiao, Yongxu Cheng, Zhiyuan Yao
Summary: This study used 16S rRNA gene amplicon sequencing to investigate the effects of short-term probiotic application on the intestinal microbial communities of Chinese mitten crab (CMC), revealing poor probiotic colonization in CMC intestines, no significant impact on alpha-diversity, significant changes in beta-diversity, and promotion of butanoate metabolism in CMC intestinal microbiota.
AQUACULTURE RESEARCH
(2022)
Article
Environmental Sciences
Xiawei Yu, Caiyan Zhang, Keke Chen, Yuan Liu, Ying Deng, Wenbin Liu, Dingdong Zhang, Guangzhen Jiang, Xiangfei Li, Sib Sankar Giri, Se Chang Park, Cheng Chi
Summary: This study used RNA sequencing technology to investigate the changes in the hepatopancreas transcriptome of Eriocheir sinensis after long-term exposure to T-2 toxin, revealing the effects of T-2 toxin on oxidative stress, apoptosis, autophagy, glucolipid metabolism, and protein synthesis. This provides a foundation for further research on the molecular toxicity mechanism of T-2 toxin in aquatic crustaceans.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2023)
Article
Engineering, Multidisciplinary
Fang Guo, Wei Han, Xi-chao Su, Yu-jie Liu, Rong-wei Cui
Summary: This paper studies the problem of weapon transportation support scheduling on an aircraft carrier deck and presents a novel solution architecture. By considering the interference of the carrier-based aircraft deck layout, a mixed integer formulation is established to minimize the total objective. A bi-population immune algorithm is proposed to solve the problem, which outperforms all compared algorithms and significantly improves efficiency. The established model and algorithm effectively respond to the weapon support requirements of carrier-based aircraft under different sortie missions.
DEFENCE TECHNOLOGY
(2023)
Article
Biochemical Research Methods
Zhouxian Li, Qi Wang, Keyun Wang, Weibing Zhang, Mingliang Ye
Summary: Protein lysine monomethylation is an important post-translational modification, but enriching and identifying monomethylated lysine (Kme1) peptides is challenging. This study proposes an antibody-free chemical proteomics approach to capture Kme1 peptides and successfully identifies multiple Kme1 sites in cells.
Article
Chemistry, Applied
Zhinian Cheng, Yang Wang, Daokuan Jin, Jianxin Liu, Wenghang Wang, Yongqiang Gu, Wanxin Ni, Zhaoxuan Feng, Mingbo Wu
Summary: Porous carbon-based catalysts derived from petroleum pitch exhibit excellent propane conversion (45.6%) and alkenes selectivity (73.9%, propylene and ethylene) due to their abundant surface quinone/ketone C-O groups and appropriate adsorption/desorption strengths, providing a promising alternative for propane dehydrogenation (PDH) process.
Article
Agriculture, Multidisciplinary
Zhou Qun, Yuan Rui, Zhang Wei-yang, Gu Jun-fei, Liu Li-jun, Zhang Hao, Wang Zhi-qin, Yang Jian-chang
Summary: "Utilizing the heterosis of indica/japonica hybrid rice (IJHR) is an effective way to increase rice grain yield. Rational application of nitrogen (N) fertilizer plays a very important role in using the heterosis of IJHR to achieve its great yield potential. The study aimed to clarify the responses of grain yield and N utilization of IJHR to N application rates and the underlying physiological mechanism."
JOURNAL OF INTEGRATIVE AGRICULTURE
(2023)
Article
Environmental Sciences
Yan Yang, Li Zhou, Wenling Zhang, Yanjun Yang, Yanyan Liu, Li Pan, Yanbei Huo, Ruijuan Wang, Yupei Ba, Xiaoyu Ren, Yana Bai, Ning Cheng
Summary: This study provides further evidence that exposure to air pollutants in the first trimester of pregnancy significantly increases the risk of neural tube defects.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Engineering, Environmental
Yan Kang, Haoqin Ma, Zequan Jing, Chaonan Zhu, Yixin Li, Haiming Wu, Peng Dai, Zizhang Guo, Jian Zhang
Summary: The use of iron-modified biochar in constructed wetlands enhances the removal of benzofluoranthrene and ammonium by increasing microbial degradation. The iron-mediated biochar increases dissolved organic carbon content and enriches microbial abundance and key enzymes involved in PAH degradation. This study confirms that the use of iron-modified biochar in constructed wetlands enhances PAH removal.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Xinyuan Chen, Ying Cao, Kaixuan Zhang, Zhen Wang, Xuejie Xie, Yunxiang Wang, Kuo Men, Jianrong Dai
Summary: This study investigated the feasibility of synthesizing MRI images at different rotation angles using deep learning. The results showed that CycleGAN can synthesize MRI images in prone and lateral positions, which could be beneficial for gantry-free radiation therapy.
Review
Materials Science, Biomaterials
Ran Wei, Danjie Li, Sheng Jia, Yuhong Chen, Jiqiu Wang
Summary: Obesity has become a critical health burden during the global pandemic, and the melanocortin receptor-4 (MC4R) has been identified as a key genetic factor in severe and early onset obesity. Previous studies have focused on the central role of MC4R in energy intake and expenditure, but evidence suggests its expression in peripheral systems as well. This review aims to provide a comprehensive understanding of the central and peripheral roles of MC4R in energy metabolism and endocrine hormone homeostasis.
Article
Chemistry, Analytical
Jianglong Yao, Yujie Liu, Bingying Jiang, Ruo Yuan, Yun Xiang
Summary: A highly sensitive electrochemical and enzyme-free biosensor is developed for detecting LCN1 using a new aptamer triplex switch probe and dual signal amplification. The sensor can sensitively detect LCN1 from 5 pM to 1 nM with a detection limit of 0.85 pM. It also exhibits high interfering protein discrimination capability and can be used to monitor low levels of LCN1 in diluted tear samples.
Article
Chemistry, Multidisciplinary
Yuyan Li, Fanghua Zhang, Wendong Liu, Mingzheng Shao, Zhe Hao, Hongyan Zhang, Ruizhong Zhang, Xiyan Li, Libing Zhang
Summary: A DNA nanoprobe activated by glutathione (GSH) was developed for spatially selective sensing and imaging of miRNA in living cells. The nanoprobe consisted of metal-organic frameworks (MOFs) and DNA hairpin probes tethered to the MOF surface, with a disulfide bond in the hairpin loop. Cleavage of the disulfide bond by GSH triggered a strand-displacement reaction with target miRNAs, enabling fluorescence signal readout in situ. The combination of endogenous GSH activation and MOF improved the spatial resolution of miRNA detection and imaging.
CHEMICAL COMMUNICATIONS
(2023)
Article
Engineering, Multidisciplinary
Yuanyuan Wang, Rui Wang, Xiaofeng Ren, Junan Lei
Summary: In order to improve the density and accuracy of 3D texture measurement in pavement function evaluation, the traditional binocular reconstruction technology was improved in three aspects. Firstly, a single moving laser line was introduced for global scanning constraints to overcome the difficulty of installing and recognizing excessive laser lines. Secondly, four improved algorithms, including disparity replacement, superposition synthesis, subregion segmentation, and subregion segmentation centroid enhancement, were developed based on different constraint mechanisms. Lastly, an improved binocular reconstruction test device was developed to achieve the dual functions of 3D texture measurement and precision self-evaluation. Results showed that the introduction of a single laser line scanning constraint improved the measurement's accuracy. Among the various improved algorithms, the subregion segmentation centroid enhancement method had the best improvement effect and can be considered for use in pavement function evaluation.
CMES-COMPUTER MODELING IN ENGINEERING & SCIENCES
(2023)
Article
Chemistry, Multidisciplinary
Xiang Qin, Jingjing Liu, Genhui Teng, Baorui Liu, Yanhui Xie, Lin Ma, Dongying Hu
Summary: P25/PBP-TiO2 photoanode and N-doped porous carbon-supported Ni nanoparticles (Ni@NPC-X) were used in dye-sensitized solar cells (DSSCs) as the photoanode and counter electrode, respectively, creating a new perspective for blueberry-based photo-powered energy systems. The introduction of PBP into the P25 photoanode and the N doping of the porous carbon improved the adsorption capacity and electron transfer of the electrodes, resulting in higher power conversion efficiency (PCE) and good electrocatalysis and cycle stability.
Article
Integrative & Complementary Medicine
Yuehong Zhang, Dandan Dong, Youqin Yan, Hao Zhang, Guangli Wang, Wei Zhou, Wei Li, Li Qiu, Tingming Li, Quan Liu, Ping Xia, Lina Mao, Danlin Yang, Lu Yang, Fengmei Lian, Xiaolin Tong, Yuanming Ba
Summary: This study evaluated the effectiveness and safety of Jinshuibao capsules, a Traditional Chinese Medicine, in treating residual cardiopulmonary symptoms in convalescent COVID-19 patients. The results showed that after two weeks of treatment, the improvement rates and full recovery rates of symptoms such as dry cough, shortness of breath, sweating, chest tightness, and palpitation were significantly higher in the Jinshuibao group compared to the control group. The study suggests that Jinshuibao capsules have the potential to improve cardiopulmonary symptoms in convalescent COVID-19 patients with minimal adverse events.
JOURNAL OF TRADITIONAL CHINESE MEDICINE
(2023)
Article
Fisheries
Xiaochen Zhu, Penny Miller-Ezzy, Mark Gluis, Jianguang Qin, Youhong Tang, Yibing Liu, Yingying Zhao, Xiaoxu Li
Summary: This study investigated the effect of adding lipids and antioxidants on the survival rate of frozen mussel oocytes. The results showed that supplementing phospholipids or antioxidants in the base cryoprotectant agent significantly increased the survival rate of mussel larvae. Additionally, adding salmon lipid extract resulted in the highest survival rate and increased the number of mussel spat.
Article
Radiology, Nuclear Medicine & Medical Imaging
Ling Wang, Sidong Li, Yandong Liu, Kai Li, Lu Yin, Yongbin Su, Zhe Guo, Li Xu, Pengju Huang, Jian Geng, Wenshuang Zhang, Kangkang Ma, Kebin Cheng, Dong Yan, Glen M. Blake, Bo He, Yajun Liu, Xiaoguang Cheng
Summary: Increased bone marrow fat is associated with lower vBMD in both sexes. However, the relationship between marrow fat and other adipose tissues with vertebral fractures is not significant after adjusting for age.
EUROPEAN RADIOLOGY
(2023)