Polyunsaturated fatty acid deficiency affects sulfatides and other sulfated glycans in lysosomes through autophagy‐mediated degradation

Reciprocal surface expression of arylsulfatase A and ubiquitin in normal and defective mammalian spermatozoa

(2020) Kathleen M. Kelsey et al.   CELL AND TISSUE RESEARCH

Glycosaminoglycans from Alzheimer’s disease hippocampus have altered capacities to bind and regulate growth factors activities and to bind tau

(2019) Minh Bao Huynh et al.   PLoS One

Human Papillomavirus 11 Early Protein E6 Activates Autophagy by Repressing AKT/mTOR and Erk/mTOR

(2019) Boya Zhang et al.   JOURNAL OF VIROLOGY

The hypothalamus as the primary brain region of metabolic abnormalities in APP/PS1 transgenic mouse model of Alzheimer's disease

(2018) Hong Zheng et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The Renoprotective Effects of Docosahexaenoic Acid as an Add-on Therapy in Patients Receiving Eicosapentaenoic Acid as Treatment for IgA Nephropathy: A Pilot Uncontrolled Trial

(2018) Takahito Moriyama et al.   INTERNAL MEDICINE

Glycosaminoglycans have variable effects on α-synuclein aggregation and differentially affect the activities of the resulting amyloid fibrils

(2018) Surabhi Mehra et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

1,3-Dichloro-2-Propanol inhibits autophagy via P53/AMPK/mTOR pathway in HepG2 cells

(2018) Bijun Cheng et al.   FOOD AND CHEMICAL TOXICOLOGY

Impact of chronic kidney dysfunction on serum Sulfatides and its metabolic pathway in mice

(2018) Yosuke Yamada et al.   GLYCOCONJUGATE JOURNAL

Omega-3 polyunsaturated fatty acids promote amyloid-β clearance from the brain through mediating the function of the glymphatic system

(2017) Huixia Ren et al.   FASEB JOURNAL

Decreased Fatty Acid β-Oxidation Is the Main Cause of Fatty Liver Induced by Polyunsaturated Fatty Acid Deficiency in Mice

(2017) Takero Nakajima et al.   TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE

The yin and yang of autophagy in acute kidney injury

(2016) Anette Melk et al.   Autophagy

Atg5-mediated autophagy deficiency in proximal tubules promotes cell cycle G2/M arrest and renal fibrosis

(2016) Huiyan Li et al.   Autophagy

Thalamic pathology and memory loss in early Alzheimer’s disease: moving the focus from the medial temporal lobe to Papez circuit

(2016) John P. Aggleton et al.   BRAIN

Chondroitin sulfate and neuronal disorders

(2016) Hiroshi Kitagawa   Frontiers in Bioscience-Landmark

Low C24-OH and C22-OH sulfatides in human renal cell carcinoma

(2016) Il Chan Kim et al.   JOURNAL OF MASS SPECTROMETRY

Melatonin attenuates MPTP-induced neurotoxicity via preventing CDK5-mediated autophagy and SNCA/α-synuclein aggregation

(2015) Ling-Yan Su et al.   Autophagy

Binding of the pathogen receptor HSP90AA1 to avibirnavirus VP2 induces autophagy by inactivating the AKT-MTOR pathway

(2015) Boli Hu et al.   Autophagy

Novel inducers of BECN1-independent autophagy:cis-unsaturated fatty acids

(2015) Mireia Niso-Santano et al.   Autophagy

Arachidonic acid diet attenuates brain Aβ deposition in Tg2576 mice

(2015) Takashi Hosono et al.   BRAIN RESEARCH

Metabolic and Non-Cognitive Manifestations of Alzheimer’s Disease: The Hypothalamus as Both Culprit and Target of Pathology

(2015) Makoto Ishii et al.   Cell Metabolism

Unsaturated fatty acids induce non-canonical autophagy

(2015) M. Niso-Santano et al.   EMBO JOURNAL

Unsaturated fatty acid-induced non-canonical autophagy: unusual? or unappreciated?

(2015) V. A. Bankaitis   EMBO JOURNAL

Ebselen reduces autophagic activation and cell death in the ipsilateral thalamus following focal cerebral infarction

(2015) Yiliang Li et al.   NEUROSCIENCE LETTERS

Omega-3 Fatty Acids in Early Prevention of Inflammatory Neurodegenerative Disease: A Focus on Alzheimer’s Disease

(2015) J. Thomas et al.   Biomed Research International

Mechanisms of axon regeneration and its inhibition: Roles of sulfated glycans

(2014) Kenji Kadomatsu et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Sulfatide, A Major Lipid Component of Myelin Sheath, Activates Inflammatory Responses As an Endogenous Stimulator in Brain-Resident Immune Cells

(2014) S.-B. Jeon et al.   JOURNAL OF IMMUNOLOGY

Discovery of essential fatty acids

(2014) Arthur A. Spector et al.   JOURNAL OF LIPID RESEARCH

Protective Properties of Neural Extracellular Matrix

(2014) Anne Suttkus et al.   MOLECULAR NEUROBIOLOGY

Polyunsaturated fatty acids and their metabolites in brain function and disease

(2014) Richard P. Bazinet et al.   NATURE REVIEWS NEUROSCIENCE

Sulodexide and glycosaminoglycans in the progression of renal disease

(2014) V. Masola et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Autophagy in Acute Kidney Injury and Repair

(2014) Liyu He et al.   NEPHRON CLINICAL PRACTICE

mTOR and autophagy: A dynamic relationship governed by nutrients and energy

(2014) E.A. Dunlop et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Altered autophagy in the mice with a deficiency of saposin A and saposin B

(2013) Ying Sun et al.   Autophagy

Substrate recognition in selective autophagy and the ubiquitin–proteasome system

(2013) Anne Schreiber et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Effect of castration on renal glycosaminoglycans and their urinary excretion in male and female rats with chronic renal failure

(2013) C.C.S. Lemos et al.   BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH

Reduced Sulfation of Chondroitin Sulfate but Not Heparan Sulfate in Kidneys of Diabetic db/db Mice

(2013) Trine M. Reine et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Dietary fat modification in patients with chronic kidney disease: n-3 fatty acids and beyond

(2013) Xiaoyan Huang et al.   JOURNAL OF NEPHROLOGY

Specific changes of sulfatide levels in individuals with pre-clinical Alzheimer's disease: an early event in disease pathogenesis

(2013) Hua Cheng et al.   JOURNAL OF NEUROCHEMISTRY

Nutrient regulation of the mTOR Complex 1 signaling pathway

(2013) Sang Gyun Kim et al.   MOLECULES AND CELLS

Sulfatides are required for renal adaptation to chronic metabolic acidosis

(2013) P. Stettner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Time course study of Aβ formation and neurite outgrowth disruption in differentiated human neuroblastoma cells exposed to H2O2: Protective role of autophagy

(2013) Ghorbangol Ashabi et al.   TOXICOLOGY IN VITRO

Beclin 1 knockdown inhibits autophagic activation and prevents the secondary neurodegenerative damage in the ipsilateral thalamus following focal cerebral infarction

(2012) Shihui Xing et al.   Autophagy

Low Cerebrospinal Fluid Sulfatide Predicts Progression of White Matter Lesions – The LADIS Study

(2012) Michael Jonsson et al.   DEMENTIA AND GERIATRIC COGNITIVE DISORDERS

A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB

(2012) Carmine Settembre et al.   EMBO JOURNAL

Wogonoside induces autophagy in MDA-MB-231 cells by regulating MAPK-mTOR pathway

(2012) Yajing Sun et al.   FOOD AND CHEMICAL TOXICOLOGY

Role of sulfatide in normal and pathological cells and tissues

(2012) Tadanobu Takahashi et al.   JOURNAL OF LIPID RESEARCH

Imaging of complex sulfatides SM3 and SB1a in mouse kidney using MALDI-TOF/TOF mass spectrometry

(2011) Christian Marsching et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

The autophagy initiating kinase ULK1 is regulated via opposing phosphorylation by AMPK and mTOR

(2011) Dan Egan et al.   Autophagy

Characterization of the CLEAR network reveals an integrated control of cellular clearance pathways

(2011) Michela Palmieri et al.   HUMAN MOLECULAR GENETICS

Autophagosomes accumulation is associated with β-amyloid deposits and secondary damage in the thalamus after focal cortical infarction in hypertensive rats

(2011) Jian Zhang et al.   JOURNAL OF NEUROCHEMISTRY

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(2011) Noemi Fabelo et al.   MOLECULAR MEDICINE

Nutritional omega-3 deficiency abolishes endocannabinoid-mediated neuronal functions

(2011) Mathieu Lafourcade et al.   NATURE NEUROSCIENCE

TFEB Links Autophagy to Lysosomal Biogenesis

(2011) C. Settembre et al.   SCIENCE

Selective desorption/ionization of sulfatides by MALDI-MS facilitated using 9-aminoacridine as matrix

(2010) Hua Cheng et al.   JOURNAL OF LIPID RESEARCH

Pathogenic Lysosomal Depletion in Parkinson's Disease

(2010) B. Dehay et al.   JOURNAL OF NEUROSCIENCE

Mechanisms of n-3 fatty acid-mediated development and maintenance of learning memory performance

(2010) Hui-Min Su   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

The Pathogenic Implication of Abnormal Interaction Between Apolipoprotein E Isoforms, Amyloid-beta Peptides, and Sulfatides in Alzheimer’s Disease

(2010) Xianlin Han   MOLECULAR NEUROBIOLOGY

Functions of Chondroitin Sulfate and Heparan Sulfate in the Developing Brain

(2010) N. Maeda et al.   NEUROCHEMICAL RESEARCH

Sulfatides facilitate apolipoprotein E-mediated amyloid- peptide clearance through an endocytotic pathway

(2008) Youchun Zeng et al.   JOURNAL OF NEUROCHEMISTRY