Evolution of chromone-like compounds as potential antileishmanial agents, through the 21st century

Challenges with chromone as a privileged scaffold in drug discovery

(2018) Carlos F. M. Silva et al.   Expert Opinion on Drug Discovery

Phytochemical investigation and biological activities of Echium arenarium (Guss) extracts

(2018) Sarra Kefi et al.   MICROBIAL PATHOGENESIS

Chromones: privileged scaffolds for the production of multi-target-directed-ligand agents for the treatment of Alzheimer’s disease

(2018) Carlos F. M. Silva et al.   Expert Opinion on Drug Discovery

Synthesis and antiprotozoal activity of furanchalcone–quinoline, furanchalcone–chromone and furanchalcone–imidazole hybrids

(2017) Elisa García et al.   MEDICINAL CHEMISTRY RESEARCH

Synthesis, leishmanicidal, trypanocidal and cytotoxic activities of quinoline-chalcone and quinoline-chromone hybrids

(2017) Juan C. Coa et al.   MEDICINAL CHEMISTRY RESEARCH

Chromones: A Promising Ring System for New Anti-inflammatory Drugs

(2016) Carlos F. M. Silva et al.   ChemMedChem

Worldwide risk factors in leishmaniasis

(2016) A. Oryan et al.   Asian Pacific Journal of Tropical Medicine

Phytochemical composition, antiparasitic and α–glucosidase inhibition activities from Pelliciera rhizophorae

(2015) Dioxelis López et al.   Chemistry Central Journal

Antivascular and anti-parasite activities of natural and hemisynthetic flavonoids from New Caledonian Gardenia species (Rubiaceae)

(2015) Linh H. Mai et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Effect of Apigenin on Leishmania amazonensis Is Associated with Reactive Oxygen Species Production Followed by Mitochondrial Dysfunction

(2015) Fernanda Fonseca-Silva et al.   JOURNAL OF NATURAL PRODUCTS

Two polymethoxylated flavonoids with antioxidant activities and a rearranged clerodane diterpenoid from the leaf exudates of Microglossa pyrifolia

(2015) Aggrey Akimanya et al.   Phytochemistry Letters

Chromones as a privileged scaffold in drug discovery: A review

(2014) Rangappa S. Keri et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Leishmaniasis

(2014) David Pace   JOURNAL OF INFECTION

Synthesis, Leishmanicidal and Cytotoxic Activity of Triclosan-Chalcone, Triclosan-Chromone and Triclosan-Coumarin Hybrids

(2014) Elver Otero et al.   MOLECULES

Dietary flavonoids fisetin, luteolin and their derived compounds inhibit arginase, a central enzyme in Leishmania (Leishmania) amazonensis infection

(2013) Leticia Correa Manjolin et al.   FOOD CHEMISTRY

Chromone linked nitrone derivative induces the expression of iNOS2 and Th1 cytokines but reduces the Th2 response in experimental visceral leishmaniasis

(2013) Suvadip Mallick et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

An Update on Natural Occurrence and Biological Activity of Chromones

(2012) S. K. Sharma et al.   CURRENT MEDICINAL CHEMISTRY

The leishmanicidal flavonols quercetin and quercitrin target Leishmania (Leishmania) amazonensis arginase

(2012) Edson Roberto da Silva et al.   EXPERIMENTAL PARASITOLOGY

Flavonoid Dimers as Novel, Potent Antileishmanial Agents

(2012) Iris L. K. Wong et al.   JOURNAL OF MEDICINAL CHEMISTRY

Pyrone and Unusually Furanone-substituted Flavones from the Leaves of Hoslundia opposita

(2012) Rim Salame et al.   PLANTA MEDICA

Purine salvage in Leishmania: complex or simple by design?

(2012) Jan M. Boitz et al.   TRENDS IN PARASITOLOGY

Protective Therapy with Novel Chromone Derivative against Leishmania donovani Infection Induces Th1 Response in vivo

(2011) Suvadip Mallick et al.   CHEMOTHERAPY

Plant derived therapeutics for the treatment of Leishmaniasis

(2011) Rupashree Sen et al.   PHYTOMEDICINE

Antiparasitic Activity of C-Geranyl Flavonoids from Mimulus bigelovii

(2011) Manar M. Salem et al.   PHYTOTHERAPY RESEARCH

Polyamine metabolism in Leishmania: from arginine to trypanothione

(2010) Gianni Colotti et al.   AMINO ACIDS

Anti-leishmanial effects of purified compounds from aerial parts of Baccharis uncinella C. DC. (Asteraceae)

(2010) Luiz Felipe D. Passero et al.   PARASITOLOGY RESEARCH

In vitro antileishmanial, antiplasmodial and cytotoxic activities of phenolics and triterpenoids from Baccharis dracunculifolia D. C. (Asteraceae)

(2009) A.A. da Silva Filho et al.   FITOTERAPIA

Antileishmaniasis Activity of Flavonoids fromConsolidaoliveriana

(2009) Clotilde Marín et al.   JOURNAL OF NATURAL PRODUCTS

Antiplasmodial and leishmanicidal activity of biflavonoids from Indian Selaginella bryopteris

(2008) Olaf Kunert et al.   Phytochemistry Letters