Comparing a knowledge-driven approach to a supervised machine learning approach in large-scale extraction of drug-side effect relationships from free-text biomedical literature

Large-scale combining signals from both biomedical literature and the FDA Adverse Event Reporting System (FAERS) to improve post-marketing drug safety signal detection

(2014) Rong Xu et al.   BMC BIOINFORMATICS

Large-scale extraction of accurate drug-disease treatment pairs from biomedical literature for drug repurposing

(2013) Rong Xu et al.   BMC BIOINFORMATICS

Chapter 16: Text Mining for Translational Bioinformatics

(2013) K. Bretonnel Cohen et al.   PLoS Computational Biology

Extraction of potential adverse drug events from medical case reports

(2013) Harsha Gurulingappa et al.   Journal of Biomedical Semantics

Pharmacogenomics Knowledge for Personalized Medicine

(2012) M Whirl-Carrillo et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

STITCH 3: zooming in on protein-chemical interactions

(2011) M. Kuhn et al.   NUCLEIC ACIDS RESEARCH

Drug Discovery Using Chemical Systems Biology: Weak Inhibition of Multiple Kinases May Contribute to the Anti-Cancer Effect of Nelfinavir

(2011) Li Xie et al.   PLoS Computational Biology

Predicting new molecular targets for known drugs

(2009) Michael J. Keiser et al.   NATURE

Drug Discovery Using Chemical Systems Biology: Repositioning the Safe Medicine Comtan to Treat Multi-Drug and Extensively Drug Resistant Tuberculosis

(2009) Sarah L. Kinnings et al.   PLoS Computational Biology

Drug Target Identification Using Side-Effect Similarity

(2008) M. Campillos et al.   SCIENCE