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Xylan in drug delivery: A review of its engineered structures and biomedical applications

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ELSEVIER
DOI: 10.1016/j.ejpb.2020.04.016

Keywords

Xylan; Colon drug delivery; Films; Hydrogels; Nanoparticles

Funding

  1. Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior (CAPES) - Brazil [001]
  2. PROPESQ/UEPB -Brazil [4.03.00.00-5-371/2017-1]

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Xylan, an abundant biopolymer mainly extracted from plants and algae, is commonly studied for textile, food and biomedical applications. In this review, different approaches to obtain xylan-based products for drug delivery purposes were described. Investigations about xylan-based films, micro- and nanostructure, with the ability or not to swell (hydrogels), developed for biomedical applications, were summarized. Furthermore, a section on colon drug delivery and the methods that have been developed for the evaluation of these systems were presented.

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