Pegfilgrastim (PEG-G-CSF) induces anti-PEG IgM in a dose dependent manner and causes the accelerated blood clearance (ABC) phenomenon upon repeated administration in mice

Published 2020 View Full Article

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Title
Pegfilgrastim (PEG-G-CSF) induces anti-PEG IgM in a dose dependent manner and causes the accelerated blood clearance (ABC) phenomenon upon repeated administration in mice
Authors
Keywords
PEGylated protein, PEG-G-CSF, Anti-PEG antibodies, Complement activation, PEGylated liposomes
Journal
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
Volume 152, Issue -, Pages 56-62
Publisher
Elsevier BV
Online
2020-05-04
DOI
10.1016/j.ejpb.2020.04.026

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