Synthesis and biological evaluation of 4-(pyridin-4-oxy)-3-(3,3-difluorocyclobutyl)-pyrazole derivatives as novel potent transforming growth factor-β type 1 receptor inhibitors

Title
Synthesis and biological evaluation of 4-(pyridin-4-oxy)-3-(3,3-difluorocyclobutyl)-pyrazole derivatives as novel potent transforming growth factor-β type 1 receptor inhibitors
Authors
Keywords
ALK5, TGF-β inhibitor, Antitumor activity
Journal
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Volume 198, Issue -, Pages 112354
Publisher
Elsevier BV
Online
2020-04-29
DOI
10.1016/j.ejmech.2020.112354

Ask authors/readers for more resources

Reprint

Contact the author

Find Funding. Review Successful Grants.

Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.

Explore

Become a Peeref-certified reviewer

The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.

Get Started