Journal
EUROPEAN JOURNAL OF ENDOCRINOLOGY
Volume 183, Issue 5, Pages R119-R132Publisher
BIOSCIENTIFICA LTD
DOI: 10.1530/EJE-20-0548
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Funding
- National Institute on Aging [K01 AG047921]
- Doris Duke Charitable Foundation
- NIH
- Massachusetts General Hospital Department of Medicine Transformative Scholars Program
- Amgen, Inc.
- Seres Therapeutics, Inc.
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Despite well recognized improvements in obesity-related comorbidities, increasing evidence implicates bariatric surgery in the onset of adverse skeletal health outcomes. The purpose of this review is to provide a focused update in three critical areas: (i) emergent data on sleeve gastrectomy and bone loss, (ii) evidence linking bariatric surgery to incident fracture, and (iii) intervention strategies designed to mitigate surgical bone loss. Better understanding of these issues will inform our treatment of skeletal health for patients planning bariatric surgery.
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