Article
Physiology
Samuel A. Smith, Dominic Micklewright, Samantha L. Winter, Alexis R. Mauger
Summary: The study found that muscle pain induced by hypertonic saline injection interfered with the accurate reproduction of knee extensor torque, which could have detrimental effects on exercise regulation and endurance performance. The experimental group showed significantly increased variance in mean contraction torque at both 15% and 20% MVIT, as well as performed target torques at a similar pain intensity.
JOURNAL OF APPLIED PHYSIOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Colombe Otis, Emilie Bouet, Sokhna Keita-Alassane, Marilyn Frezier, Alienor Delsart, Martin Guillot, Agathe Bedard, Jean-Pierre Pelletier, Johanne Martel-Pelletier, Bertrand Lussier, Francis Beaudry, Eric Troncy
Summary: Validating animal pain models is crucial for enhancing translational research and pharmacological treatment response. This study found that a calibrated slight exercise protocol combined with multimodal analgesia had positive effects on the MI-RAT model, particularly when used in conjunction with positive analgesics, reducing sensitivity to pain and improving joint structure.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Anesthesiology
Samuel A. Smith, Ryan Norbury, Adam J. Hunt, Alexis R. Mauger
Summary: This study investigated the reliability of pain measures induced by intramuscular injections of hypertonic saline. The results showed good relative reliability for pain intensity and pain quality. However, there was substantial interindividual variability in pain measures. The study concluded that intramuscular injections of hypertonic saline can reliably induce experimental muscle pain.
EUROPEAN JOURNAL OF PAIN
(2023)
Article
Biology
Ruben Allois, Pasquale Pagliaro, Silvestro Roatta
Summary: Ischemic preconditioning (IPC) is a protective maneuver that involves alternating periods of occlusion and reperfusion of tissue blood flow. Results suggest that IPC delays fatigue onset by reducing muscle oxygen consumption. This delay in fatigue is likely due to improved metabolic efficiency of muscles.
Article
Anesthesiology
Zhiping Song, Shibiao Chen, Yang Zhang, Xiaoyun Shi, Na Zhao, Zhengyu Liao
Summary: The study demonstrated that lidocaine coinfusion can effectively alleviate vascular pain induced by hypertonic saline, with Group L showing significantly lower pain severity and incidence compared to Group C.
BMC ANESTHESIOLOGY
(2021)
Article
Sport Sciences
Robyn Feiss, Jason Kostrna, James W. Scruggs, Melissa Pangelinan, Gershon Tenenbaum
Summary: The study found that participants in both fast and slow tempo music conditions maintained a dissociative state longer during the wall-sit exercise compared to the no-music control group, but this effect was not present during the plank exercise. However, neither music condition had an impact on heart rate, perceived exertion, time to voluntary exhaustion, or mood. In the initial minutes of exercise, participants showed an increase in heart rate and perceived exertion, as well as a shift towards associative attention and high arousal state.
JOURNAL OF SPORTS SCIENCES
(2021)
Article
Rehabilitation
Derrick G. Sueki, Kim Dunleavy, Emilio J. Puentedura, Lindsey Heard, Peter Van der Heide, Ming-Shun Cheng
Summary: The study aimed to investigate whether mechanical pressure pain, short-term memory recall of a painful stimulus, or long-term memory of a previous painful lower limb injury would affect isometric muscle strength, and whether there was a difference in responses between participants with and without a previous history of injury. The findings suggest that recalled pain memory can impact motor responses and highlight the role of past injury history in the rehabilitation process.
AMERICAN JOURNAL OF PHYSICAL MEDICINE & REHABILITATION
(2023)
Article
Sport Sciences
Frederic Sabater-Pastor, Robin Faricier, Melanie Metra, Juan M. Murias, Callum G. Brownstein, Guillaume Y. Millet
Summary: This study compared the effects of running and cycling on energy cost when matched for duration and relative intensity. The results showed that cycling significantly increased energy cost at mid and end of exercise, while running did not show any changes in energy cost throughout the duration. Changes in energy cost during cycling were correlated with muscle fatigue and changes in cadence.
MEDICINE & SCIENCE IN SPORTS & EXERCISE
(2023)
Article
Sport Sciences
Leonardo G. M. Coelho, Joao B. Ferreira-Junior, Thomas B. Williams, Andre Maia-Lima, Diego A. Borba, Cristiano D. Silva, Daniel B. Coelho, Cristiano L. M. Barros, Luciano S. Prado, Emerson Silami-Garcia
Summary: The study aimed to evaluate the effect of head pre-cooling on the 5-km time-trial performance of amateur runners in the heat. Results showed that a 20-minute head cooling intervention improved 5-km running performance in a hot environment, suggesting it could be a practical pre-cooling strategy for both professional and amateur runners.
SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS
(2021)
Article
Medicine, General & Internal
Ana Onate-Figuerez, Vanesa Soto-Leon, Juan Avendano-Coy, Laura Mordillo-Mateos, Yolanda A. Perez-Borrego, Carolina Redondo-Galan, Pablo Arias, Antonio Oliviero
Summary: This study assessed hand motor fatigability in people with SCI and compared it with able-bodied individuals. The results showed that muscle force decline during a fatiguing task was similar between controls and SCI participants. Additionally, perceived fatigability and motor fatigability were largely independent in individuals with SCI.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Orthopedics
Giovanni Berardi, Christine Eble, Sandra K. Hunter, Marie Hoeger Bement
Summary: This study examined the changes in perceived pain and fatigue during and after exercise in people with and without fibromyalgia. The findings suggest that people with fibromyalgia experience significant pain and fatigue during recovery, particularly during concentric contractions.
Article
Emergency Medicine
Robert F. Deveau, Kaylee K. Marino, Kaitlin E. Crowley, Kevin C. McLaughlin, Sarah E. Culbreth
Summary: This study aimed to evaluate the incidence of infusion-related adverse events (IRAE) associated with peripheral administration of 3% sodium chloride. The results showed that the incidence of IRAE was associated with the duration of infusion, and the majority of events were mild with no permanent tissue injury.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2023)
Article
Sport Sciences
Joungbo Ko, Young C. Jang, John Quindry, Rodney Guttmann, Ludmila Cosio-Lima, Scott K. Powers, Youngil Lee
Summary: This study aimed to investigate the relationship between cardiac anomalies and metabolic disorders, as well as explore the role of endurance exercise in protecting the heart. The results demonstrated that endurance exercise improved obesity and hyperglycemia caused by a high-fat/high-fructose diet, and alleviated cardiac dysfunction. Moreover, endurance exercise inhibited cellular senescence and inflammation, promoted autophagy and apoptosis, thereby protecting the heart from metabolic distress.
MEDICINE & SCIENCE IN SPORTS & EXERCISE
(2023)
Article
Rehabilitation
Carlos Cruz-Montecinos, Rodrigo Nunez-Cortes, Benjamin Guzman-Gonzalez, Lars L. Andersen, Xavier Garcia-Masso, Joaquin Calatayud
Summary: A self-regulated dual task can increase trunk muscle endurance in patients after lumbar diskectomy, especially during back extension. The difference observed in time to failure between single task and dual task is associated with fear avoidance, and may be used to improve trunk muscle endurance, particularly for patients with high levels of fear avoidance.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2021)
Article
Neurosciences
Ryan Norbury, Samuel A. Smith, Mark Burnley, Megan Judge, Alexis R. Mauger
Summary: This study investigated the effects of muscle pain on neuromuscular and neurophysiological responses in the contralateral limb. The results showed that muscle pain can reduce endurance performance time and decrease voluntary force, but had no effect on doublet amplitude and MEP center dot M-max(-1) measures.
EXPERIMENTAL BRAIN RESEARCH
(2022)
Article
Physiology
Samuel A. Smith, Dominic Micklewright, Samantha L. Winter, Alexis R. Mauger
Summary: The study found that muscle pain induced by hypertonic saline injection interfered with the accurate reproduction of knee extensor torque, which could have detrimental effects on exercise regulation and endurance performance. The experimental group showed significantly increased variance in mean contraction torque at both 15% and 20% MVIT, as well as performed target torques at a similar pain intensity.
JOURNAL OF APPLIED PHYSIOLOGY
(2021)
Article
Psychology, Biological
Raul Canestri, Paulo Estevao Franco-Alvarenga, Cayque Brietzke, Italo Vinicius, Samuel A. Smith, Alexis R. Mauger, Marcio Fagundes Goethel, Flavio Oliveira Pires
Summary: This study investigated the impact of experimentally induced muscle pain on endurance performance, showing that hypertonic injection-induced muscle pain can lead to alterations in motor command and cortical activation, as well as an interplay of perceptual responses, ultimately affecting endurance exercise outcomes.
Article
Chemistry, Analytical
Carol M. E. Smyth, Samantha L. Winter, John W. Dickinson
Summary: This study demonstrates that real-time OEP phase angle feedback intervention can significantly improve breathing pattern synchrony in individuals with dysfunctional breathing patterns, leading to a transition towards a healthier breathing pattern.
Article
Physiology
Ryan Norbury, Samuel A. Smith, Mark Burnley, Megan Judge, Alexis R. Mauger
Summary: Muscle pain can reduce exercise performance by exacerbating neuromuscular fatigue, which is centrally mediated through inhibitory feedback from group III/IV nociceptors.
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY
(2022)
Article
Neurosciences
Ryan Norbury, Samuel A. Smith, Mark Burnley, Megan Judge, Alexis R. Mauger
Summary: This study investigated the effects of muscle pain on neuromuscular and neurophysiological responses in the contralateral limb. The results showed that muscle pain can reduce endurance performance time and decrease voluntary force, but had no effect on doublet amplitude and MEP center dot M-max(-1) measures.
EXPERIMENTAL BRAIN RESEARCH
(2022)
Article
Sport Sciences
Michele Girardi, Chiara Gattoni, Luca Sponza, Samuele Maria Marcora, Dominic Micklewright
Summary: This study compares the predictive accuracy of the power law, 2-parameter hyperbolic, and linear models on elite 1-hour track running performance, and evaluates the pacing profile and running pattern of the best two performances in men's history. The results suggest that the power law model may provide a more realistic prediction for 1-hour track running performance. Even pacing seems to be the best strategy for success in this type of running event.
SPORT SCIENCES FOR HEALTH
(2022)
Article
Physiology
Callum A. O'Malley, Christopher L. Fullerton, Alexis R. Mauger
Summary: Using exercise protocols at a fixed rating of perceived effort (RPE) is a useful method for exploring the psychophysical influences on exercise performance. However, studies have often arbitrarily selected RPE values without considering their correspondence to exercise intensity thresholds and domains. Aligning RPE intensities with established physiological thresholds seems more appropriate, although the reliability of this method has not been assessed.
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY
(2022)
Article
Anesthesiology
Samuel A. Smith, Ryan Norbury, Adam J. Hunt, Alexis R. Mauger
Summary: This study investigated the reliability of pain measures induced by intramuscular injections of hypertonic saline. The results showed good relative reliability for pain intensity and pain quality. However, there was substantial interindividual variability in pain measures. The study concluded that intramuscular injections of hypertonic saline can reliably induce experimental muscle pain.
EUROPEAN JOURNAL OF PAIN
(2023)
Review
Psychology, Clinical
Stanley Wong, An Yi Yu, Nicholas Fabiano, Ofer Finkelstein, Aryan Pasricha, Brett D. M. Jones, Joshua D. Rosenblat, Daniel M. Blumberger, Benoit H. Mulsant, M. Ishrat Husain
Summary: Interest in using psychedelic therapies for mental and substance use disorders has increased. Psilocybin, a classic serotonergic psychedelic, has emerged as a primary focus in clinical research. However, there is limited data on the safety and efficacy of other serotonergic psychedelics.
JOURNAL OF PSYCHOACTIVE DRUGS
(2023)
Article
Sport Sciences
Stephen Wong, Mark Burnley, Alexis Mauger, Sun Fenghua, James Hopker
Summary: This study examined the physiological responses during exercise at FTP and FTP+15W. The results showed that the time to task failure and VO2peak were significantly different between FTP and FTP+15W. Additionally, there was a significant difference in blood lactate levels. Therefore, FTP should not be considered a threshold marker for heavy and severe intensity.
JOURNAL OF SPORTS SCIENCES
(2022)
Article
Physiology
Christopher R. J. Fennell, Alexis R. Mauger, James G. Hopker
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY
(2023)
Article
Sport Sciences
Carol M. E. Smyth, Samantha L. Winter, John W. Dickinson
Summary: There is currently no definitive diagnostic method for breathing pattern disorders (BPD), but this study investigated the use of optoelectronic plethysmography (OEP) to differentiate between individuals with and without BPD. The results showed that OEP can effectively distinguish BPD from healthy individuals at rest and during exercise, based on measures of regional contribution and phase angles. The characteristics of BPD include asynchronous and thoracic dominant breathing patterns.
TRANSLATIONAL SPORTS MEDICINE
(2022)