Article
Computer Science, Information Systems
Pankush Kalgotra, Ramesh Sharda
Summary: In this study, a novel model combining network science and deep learning was developed to predict hospital Length of Stay (LOS) by creating a construct of latent comorbidities and using large-scale patient records. The model achieved a low mean absolute percent error of 29.8% across all disease categories, demonstrating its effectiveness in accurately estimating expected LOS for patients.
JOURNAL OF MANAGEMENT INFORMATION SYSTEMS
(2021)
Article
Medicine, General & Internal
Ahmet Balun, Alkame Akgumus
Summary: Elderly patients with acute coronary syndrome (ACS) are more fragile due to the burden of comorbidity. The Charlson Comorbidity Index (CCI) was used to assess the impact of comorbidity on 1-year mortality and clinical outcomes in elderly ACS patients who underwent percutaneous coronary intervention. Higher CCI scores were associated with increased stroke development and mortality rates in this population.
Article
Environmental Sciences
Jin Feng, Dawei Cao, Dashan Zheng, Zhengmin (Min) Qian, Cunrui Huang, Huiqing Shen, Yi Liu, Qiyong Liu, Jimin Sun, Guangyuan Jiao, Xiaoran Yang, Stephen Edward McMillin, Chongjian Wang, Hualiang Lin, Xinri Zhang, Shiyu Zhang
Summary: This study found significant associations between cold spells and hospital admissions, length of hospital stay, and hospitalization expenses for respiratory diseases. Compared with the non-cold spell period, the overall cumulative risk of hospitalization for total respiratory diseases on cold spell days was 1.232 (95% CI: 1.090, 1.394), with increased length of hospital stay and hospitalization expenses of 112.793 (95% CI: 10.755, 214.830) days and 127.568 (95% CI: 40.513, 214.624) thousand Chinese yuan, respectively. The cumulative risks of cold spells on total respiratory diseases and pneumonia were statistically significant. Harvesting effects were also observed in the associations between cold spells and hospital admission, length of hospital stay, and hospitalization expenses for respiratory diseases.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Review
Cardiac & Cardiovascular Systems
Alexander G. Truesdell, Mirvat A. Alasnag, Prashant Kaul, Syed Tanveer Rab, Robert F. Riley, Michael N. Young, Wayne B. Batchelor, Akiko Maehara, Frederick G. Welt, Ajay J. Kirtane, ACC Interventional Counci
Summary: Coronary angiography has been the standard for diagnosing coronary artery disease and guiding percutaneous coronary intervention (PCI). Intravascular imaging (IVI) technologies are used in conjunction with angiography to better assess plaque morphology and optimize PCI. IVI has utility in preintervention assessment, procedural guidance, and postintervention evaluation. IVI's role in reducing major adverse cardiac events in complex lesions is emerging, and further studies are underway. This paper provides an overview of available IVI technologies, reviews evidence supporting their use in PCI, and advocates for broader utilization.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2023)
Article
Public, Environmental & Occupational Health
Xinchen Ke, Wenrui Lin, Daishi Li, Shuang Zhao, Mingliang Chen, Yi Xiao, Xiang Chen, Minxue Shen, Juan Su
Summary: This study described the economic burden of melanoma patients in Hunan province, China, and investigated the factors influencing hospitalization spending and length of stay in patients undergoing melanoma surgery. The findings showed that melanoma imposes a heavy economic burden on patients, with middle-aged men with melanoma on the limbs experiencing the highest financial burden.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Medicine, General & Internal
Rocco Papalia, Guglielmo Torre, Anna Maria Alifano, Erika Albo, Giuseppe Francesco Papalia, Marco Bravi, Antonio De Vincentis, Emanuele Zappala, Biagio Zampogna, Vincenzo Denaro
Summary: Factors such as arterial hypertension, diabetes mellitus, surgical time, and intraoperative blood loss significantly influence the length of hospital stay in total knee arthroplasty. Stabilizing comorbidities and optimizing laboratory values can help reduce the overall healthcare burden in inpatient settings.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Steven M. Bradley, Lisa A. Kaltenbach, Katelyn Xiang, Amit P. Amin, Paul L. Hess, Thomas M. Maddox, Anil Poulose, Emmanouil S. Brilakis, Paul Sorajja, P. Michael Ho, Sunil V. Rao
Summary: This study examined the trends and hospital variation in same-day discharge following elective PCI, and evaluated the association between same-day discharge trends and patient outcomes. The research found that there was a significant increase in same-day discharge following elective PCI over the past decade, but this increase was not associated with worse 30-day mortality or rehospitalization rates.
JACC-CARDIOVASCULAR INTERVENTIONS
(2021)
Article
Medicine, General & Internal
Rocco Papalia, Biagio Zampogna, Guglielmo Torre, Giuseppe Francesco Papalia, Ferruccio Vorini, Marco Bravi, Erika Albo, Antonio De Vincentis, Vincenzo Denaro
Summary: This retrospective study evaluated the correlation between preoperative and perioperative factors and the length of hospital stay in total hip arthroplasty patients. Factors such as operative time, preoperative serum creatinine, intraoperative blood loss, and surgical approach were found to significantly correlate with increased hospitalization length. Logistic regression model showed an AUC of 0.748, indicating the important role of various variables in influencing hospital stay length.
JOURNAL OF CLINICAL MEDICINE
(2021)
Review
Cardiac & Cardiovascular Systems
Niels M. R. van der Sangen, Rik Rozemeijer, Dean R. P. P. Chan Pin Yin, Marco Valgimigli, Stephan Windecker, Stefan K. James, Sergio Buccheri, Jurrien M. ten Berg, Jose P. S. Henriques, Michiel Voskuil, Wouter J. Kikkert
Summary: Dual antiplatelet therapy is the standard of care for patients with chronic coronary syndrome and acute coronary syndrome undergoing percutaneous coronary intervention, but selecting the optimal duration and composition of treatment poses a major challenge. Current guidelines recommend risk stratification for tailoring treatment, yet various risk scoring methods and testing approaches have not been widely adopted in clinical practice. Further research and validation are needed to determine the effectiveness of these risk stratification methods in improving clinical outcomes.
EUROPEAN HEART JOURNAL
(2021)
Article
Gastroenterology & Hepatology
Zubair Bayat, Erin D. Kennedy, J. Charles Victor, Anand Govindarajan
Summary: This study found that surgeon factors, including low surgeon volume and increasing years-in-practice, were strongly and independently associated with longer LOS after colorectal surgery, while hospital factors did not have an independent impact. This suggests that LOS is primarily driven by surgeon-mediated care processes and may provide actionable targets for provider-level interventions to reduce LOS after CRS.
COLORECTAL DISEASE
(2023)
Review
Cardiac & Cardiovascular Systems
Davide Capodanno, Deepak L. Bhatt, C. Michael Gibson, Stefan James, Takeshi Kimura, Roxana Mehran, Sunil Rao, Philippe Gabriel Steg, Philip Urban, Marco Valgimigli, Stephan Windecker, Dominick J. Angiolillo
Summary: As the field of PCI advances, the importance of bleeding in treatment is increasingly recognized, being seen as having equally unfavorable prognostic implications as ischemic or thrombotic complications. Therefore, strategies focusing on maximizing treatment efficacy while minimizing safety concerns such as bleeding have become increasingly important.
NATURE REVIEWS CARDIOLOGY
(2022)
Article
Psychiatry
Xiaoning Shi, Yingying Zhao, Haichen Yang, Xiufeng Xu, Yiru Fang, Xin Yu, Qingrong Tan, Huichun Li, Guangqiang Sun, Hang Wu, Pengfei Wang, Jie Yang, Xuequan Zhu, Gang Wang, Ling Zhang
Summary: The aim of this study was to assess the clinical features and influencing factors of hospitalization times and length of stay in bipolar disorder (BD) patients. The results showed that better management of depressive episodes and functional rehabilitation may help reduce the length of stay. BD patients with more hospitalization times were characterized by higher risk of suicide and complex polypharmacy.
FRONTIERS IN PSYCHIATRY
(2023)
Article
Medicine, General & Internal
Ancuta Elena Vijan, Ioana Cristina Daha, Caterina Delcea, Gheorghe-Andrei Dan
Summary: This study found that acute coronary syndromes, infections, heart failure, increased NT-proBNP levels, heart failure with reduced ejection fraction, and elevated HAS-BLED score were independent predictors of extended length of hospital stay in atrial fibrillation patients.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Medicine, General & Internal
Christopher A. Rajkumar, Michael J. Foley, Fiyyaz Ahmed-Jushuf, Alexandra N. Nowbar, Florentina A. Simader, John R. Davies, Peter D. O'Kane, Peter Haworth, Helen Routledge, Tushar Kotecha, Reto Gamma, Gerald Clesham, Rupert Williams, Jehangir Din, Sukhjinder S. Nijjer, Nick Curzen, Neil Ruparelia, Manas Sinha, Jason N. Dungu, Sashiananthan Ganesananthan, Ramzi Khamis, Lal Mughal, Tim Kinnaird, Ricardo Petraco, James C. Spratt, Sayan Sen, Joban Sehmi, David J. Collier, Afzal Sohaib, Thomas R. Keeble, Graham D. Cole, James P. Howard, Darrel P. Francis, Matthew J. Shun-Shin, Rasha K. Al-Lamee
Summary: This study aimed to investigate whether PCI is more effective than a placebo procedure in relieving angina symptoms in patients with stable angina. The results showed that PCI resulted in a lower angina symptom score compared to the placebo procedure, indicating a better health status with respect to angina.
NEW ENGLAND JOURNAL OF MEDICINE
(2023)
Review
Cardiac & Cardiovascular Systems
David Hildick-Smith, Sandeep Arunothayaraj, Goran Stankovic, Shao-Liang Chen
Summary: Bifurcation coronary artery disease is common and influenced by altered endothelial shear stress. Various stenting techniques are available to treat bifurcation lesions and achieve optimal results.
Article
Cardiac & Cardiovascular Systems
Stephanie M. Spehar, Milan Seth, Peter Henke, Khaldoon Alaswad, Theodore Schreiber, Aaron Berman, John Syrjamaki, Omar E. Ali, Yousef Bader, David Nerenz, Hitinder Gurm, Devraj Sukul
Summary: The study found that Black patients had a higher risk of 90-day readmission and cumulative mortality following PCI compared with White patients. Associations were mediated by dual eligibility, community economic well-being, and traditional cardiovascular risk factors.
AMERICAN HEART JOURNAL
(2023)
Article
Multidisciplinary Sciences
Lorenzo Azzalini, Milan Seth, Devraj Sukul, Javier A. Valle, Edouard Daher, Brett Wanamaker, Michael T. Tucciarone, Anwar Zaitoun, Ryan D. Madder, Hitinder S. Gurm
Summary: The COVID-19 pandemic has affected the temporal trends and outcomes of patients undergoing percutaneous coronary intervention (PCI) in Michigan, leading to a reduction in PCI volume and an increase in risk-adjusted mortality. COVID-19 positive patients experienced worse outcomes.
Article
Cardiac & Cardiovascular Systems
Akash Kataruka, Charles C. Maynard, Ravi S. Hira, Larry Dean, Todd Dardas, Hitinder Gurm, Josiah Brown, Michael E. Ring, Jacob A. Doll
Summary: Many PCI programs in Washington State do not meet minimum volume standards despite government regulation. This certificate of need strategy has resulted in a tiered system where low-volume centers treat high-risk patients with poor outcomes, but there is not a significant increase in geographic access.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2022)
Editorial Material
Cardiac & Cardiovascular Systems
Devraj Sukul, Hitinder S. Gurm
CIRCULATION-CARDIOVASCULAR QUALITY AND OUTCOMES
(2023)
Editorial Material
Cardiac & Cardiovascular Systems
Hitinder S. Gurm, George Hanna
JACC-CARDIOVASCULAR INTERVENTIONS
(2023)
Article
Cardiac & Cardiovascular Systems
Renu Virmani, Aloke V. Finn, Matthew Kutyna, Yu Sato, Karen Meess, Cody Smith, Robert S. Chisena, Hitinder S. Gurm, Jon C. George
Summary: This study aims to assess the feasibility and treatment effect of pulsatile intravascular lithotripsy (PIVL) on calcified lesions in a cadaveric model of peripheral artery disease. The results show that PIVL treatment was successful and resulted in new fractures and luminal expansion of the vessels. Therefore, PIVL could be a promising new approach for the treatment of vascular calcification.
CARDIOVASCULAR REVASCULARIZATION MEDICINE
(2023)
Article
Surgery
Chloe A. Powell, Jeremy Albright, Jacob Culver, Nicholas H. Osborne, Matthew A. Corriere, Devraj Sukul, Hitinder Gurm, Peter K. Henke
Summary: This study evaluates the impact of race and socioeconomic status on outcomes after lower extremity bypass surgery. Black patients and socioeconomically disadvantaged patients are more likely to present with severe CLTI, leading to increased risk of amputation and other complications after the surgery.
Article
Cardiac & Cardiovascular Systems
Brett. L. L. Wanamaker, Ahmad Shoaib, Milan Seth, Devraj Sukul, Mamas. A. A. Mamas, Hitinder. S. S. Gurm
Summary: This study compared data from PCI registries in the United States and the United Kingdom, and found significant differences between the two countries in terms of the prevalence of diabetes and other comorbidities, the proportion of primary PCI, adoption of transradial PCI, and trends in mechanical support utilization.
CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS
(2023)
Article
Engineering, Biomedical
Jessie Jingxuan Lyu, Yao Liu, Hitinder S. Gurm, Albert Shih, Yihao Zheng
Summary: A miniature grinding wheel was successfully fabricated for atherectomy to remove calcified plaques in coronary and peripheral arteries. The wheel was made by nickel-diamond electroplating on a thin, flexible hollow stainless steel drive shaft. Experimental validation showed that the wheel effectively removed the calcified plaque. This research could lead to a more effective and safer treatment device for lesions deep in coronary and peripheral arteries.
MEDICAL ENGINEERING & PHYSICS
(2023)
Editorial Material
Cardiac & Cardiovascular Systems
Hitinder S. Gurm, David E. Hamilton
JACC-CARDIOVASCULAR INTERVENTIONS
(2023)
Editorial Material
Cardiac & Cardiovascular Systems
Hitinder S. Gurm, Nabeel Hyder
JACC-CARDIOVASCULAR INTERVENTIONS
(2023)
Meeting Abstract
Cardiac & Cardiovascular Systems
Ashwini Kerkar, Devraj Sukul, Milan Seth, Michael A. Lauer, M. Chadi Alraies, Elizabeth Jane Pielsticker, Gerald C. Koenig, Mamas A. Mamas, Hitinder S. Gurm
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2023)
Meeting Abstract
Cardiac & Cardiovascular Systems
Francesco Moroni, Hitinder S. Gurm, Zachary Gertz, Antonio Abbate, Lorenzo Azzalini
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2022)
Proceedings Paper
Engineering, Biomedical
Robert S. Chisena, Hitinder Gurm, Albert J. Shih
Summary: Micro-computed tomography (μCT) is a powerful tool for generating three-dimensional images of objects using penetrative X-rays. It is useful for imaging hardened biological tissues and studying the efficacy of cardiovascular devices for the treatment of intravascular calcium (IVC). This article presents a generalized approach that utilizes μCT for qualitative and quantitative analyses of the treatment effect of new devices on IVC tissue.
V CIRP CONFERENCE ON BIOMANUFACTURING
(2022)
Meeting Abstract
Cardiac & Cardiovascular Systems
Brett Wanamaker, Ahmad Shoaib, Milan Seth, Devraj Sukul, A. Mamas Mamas, Hitinder S. Gurm
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2022)