Article
Radiology, Nuclear Medicine & Medical Imaging
Guan-Yeu Chen, Teh-Fu Hsu, I-San Chan, Chia-Hao Liu, Wei-Ting Chao, Ying-Chu Shih, Ling-Yu Jiang, Yen-Hou Chang, Peng-Hui Wang, Yi-Jen Chen
Summary: This study compared the ability of the O-RADS and ADNEX models to classify benign or malignant adnexal lesions. The results showed that the O-RADS classification was comparable to the ADNEX model and had higher sensitivity at the 10% cutoff value. Additionally, the quick-access O-RADS flowchart was found to be helpful in categorization and could shorten the analysis time.
EUROPEAN RADIOLOGY
(2022)
Article
Veterinary Sciences
Adrian-Valentin Potarniche, Michal Czopowicz, Olga Szalus-Jordanow, Agata Moroz, Marcin Mickiewicz, Lucjan Witkowski, Iwona Markowska-Daniel, Emilia Bagnicka, Constantin Cerbu, Diana Olah, Marina Spinu, Jaroslaw Kaba
Summary: This study aimed to evaluate the performance of different commercial ELISAs in testing milk samples for CAE. The results show that both wELISA and TM/CA-ELISA can be interchangeably used for individual goat milk samples.
PREVENTIVE VETERINARY MEDICINE
(2021)
Article
Mathematical & Computational Biology
Larry L. Tang, Zhen Meng, Qizhai Li
Summary: This article introduces a powerful method for comparing two samples by drawing inference from ROC curve model parameters and using a comprehensive statistic based on Cauchy combination. The method is particularly useful for non-normal continuous biomarker results and performs well in various scenarios.
STATISTICS IN MEDICINE
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Davide Bellini, Nicola Panvini, Marco Rengo, Simone Vicini, Miriam Lichtner, Tiziana Tieghi, Dea Ippoliti, Federica Giulio, Elena Orlando, Mario Iozzino, Maria Grazia Ciolfi, Sarah Montechiarello, Ugo d'Ambrosio, Emanuele d'Adamo, Chiara Gambaretto, Stefano Panno, Vanessa Caldon, Cesare Ambrogi, Iacopo Carbone
Summary: This study evaluated the diagnostic accuracy and interobserver consistency of CO-RADS score in lung involvement by COVID-19, showing moderate agreement among readers with different levels of expertise and accurate diagnostic performance.
EUROPEAN RADIOLOGY
(2021)
Article
Mathematical & Computational Biology
Yi-Ting Hwang, Nan-Cheng Su
Summary: The paper discusses the accuracy assessment of diagnostic tests in medical research. Nonparametric estimators are used to calculate the variance and covariance of AUC estimates for paired designs, leading to sample size determination. Numerical results are provided due to the lack of closed-form solutions for most of the results.
BIOMETRICAL JOURNAL
(2022)
Article
Medicine, General & Internal
Mohamad Adam Bujang
Summary: Sample size calculation based on a specified width of 95% confidence interval allows researchers to determine the level of statistical accuracy they want to achieve for a study. This paper provides a conceptual background for sensitivity and specificity analysis and presents sample size tables based on a 95% confidence interval width. The paper also offers recommendations for sample size planning in diagnostic and screening scenarios, as well as discusses other relevant considerations in determining the minimum sample size and drafting the sample size statement for sensitivity and specificity analysis.
Review
Medical Laboratory Technology
Peter Schlattmann
Summary: This tutorial explains how to conduct a meta-analysis of diagnostic test accuracy studies based on 2x2 tables from primary studies. It discusses univariate methods for analyzing sensitivity and specificity, as well as logistic regression models for sensitivity with and without random effects. The use of diagnostic odds ratios (DOR) to assess publication bias is also covered. Additionally, bivariate random effects models are recommended, along with the construction of summary receiver operating characteristic (sROC) curves using a regression model. The tutorial includes instructions on performing the necessary calculations using the R software and provides an example meta-analysis of studies on Procalcitonin as a diagnostic marker for sepsis.
CLINICAL CHEMISTRY AND LABORATORY MEDICINE
(2023)
Article
Medicine, General & Internal
Wenhao Su, Tong Qiu, Meng Zhang, Cui Hao, Pengjiao Zeng, Zhangfeng Huang, Wenxing Du, Tianxiang Yun, Yunpeng Xuan, Lijuan Zhang, Yachong Guo, Wenjie Jiao
Summary: Most human diseases are accompanied by systems changes, and alkaline phosphatase has been identified as a decent systems biomarker for 19 different types of diseases. Understanding the molecular mechanisms of up-and-down-regulation of ALP activities could be key to understanding the body's reactions during disease progression.
CURRENT MEDICAL RESEARCH AND OPINION
(2022)
Article
Nursing
Yadan Chen, Limin Lv, Chunni Wu, Huan Wen, Hongxia Cai, Yujuan Xiao, Haihua Zhu
Summary: This study aimed to assess the predictive ability of the Johns Hopkins Fall Risk Assessment Tool (Chinese Version) in inpatient settings. A case-control study was conducted to determine the predictive ability of the tool using ROC curve and logistic regression analysis.
JOURNAL OF ADVANCED NURSING
(2022)
Article
Biology
M. Amico, I Van Keilegom, B. Han
Summary: This article introduces a cure model for handling cure fractions in survival data, and proposes a ROC curve estimator to evaluate the classification performance of cured/noncured status. Through simulations and comparisons, the good performance of the proposed method is demonstrated, applied to a breast cancer dataset.
Article
Mathematical & Computational Biology
Kevin J. Wilson, S. Faye Williamson, A. Joy Allen, Cameron J. Williams, Thomas P. Hellyer, B. Clare Lendrem
Summary: This article proposes a novel Bayesian approach to determine the sample size for the diagnostic accuracy study, utilizing information from the analytical validity stage. The approach uses assurance to calculate the required sample size based on the target width of a posterior probability interval and allows for the choice of using or disregarding the data from the analytical validity study. Sensitivity analyses and evaluations of prior-data conflict are performed to assess the robustness of the proposed method. The results demonstrate that the assurance-based approach can reduce the required sample size when suitable prior information is available.
STATISTICS IN MEDICINE
(2022)
Review
Psychology, Developmental
Alessio Bellato, Charlotte L. Hall, Madeleine J. Groom, Emily Simonoff, Anita Thapar, Chris Hollis, Samuele Cortese
Summary: This study conducted a systematic review and meta-analysis to evaluate the accuracy and clinical utility of the QbTest in the clinical assessment of attention-deficit/hyperactivity disorder (ADHD). The results showed that the QbTest has limited accuracy in discriminating between ADHD and non-ADHD clinical cases. However, when used as an adjunct to a full clinical assessment, the QbTest can improve assessment efficiency and reduce diagnosis time.
JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY
(2023)
Article
Oncology
Celia Touraine, Audrey Winter, Florence Castan, David Azria, Sophie Gourgou
Summary: Identifying factors that can predict the risk of late fibrosis in breast cancer patients is essential. Previous studies found RILA to be associated with late toxicities, smoking status, and hormonotherapy. This article evaluates the predictive performance of RILA and its association with other factors using a ROC curve analysis.
Article
Endocrinology & Metabolism
Antonio Garcia-Dominguez, Carlos E. Galvan-Tejada, Rafael Magallanes-Quintanar, Hamurabi Gamboa-Rosales, Irma Gonzalez Curiel, Jesus Peralta-Romero, Miguel Cruz
Summary: The development of medical diagnostic models for diabetes detection, using machine learning algorithms and feature selection techniques, has shown remarkable progress. These models, incorporating diverse datasets and prominent classifier algorithms, demonstrate superior performance with accuracies exceeding 94%. The study emphasizes the pivotal role of feature selection in optimizing the input data and improving the performance of diabetes detection models, contributing to the advancement of medical diagnostic capabilities.
JOURNAL OF DIABETES RESEARCH
(2023)
Article
Oncology
Chengzhen Bao, Jie Shen, Yue Zhang, Yan Zhang, Wei Wei, Ziteng Wang, Jia Ding, Lili Han
Summary: This study aimed to evaluate the diagnostic performance of radiologists on breast cancer with artificial intelligence (AI) support. The results showed that radiologists with AI support demonstrated improved sensitivity, agreement rate, and Kappa value, with shorter reading time.
Article
Food Science & Technology
Jose L. Horreo, Patrick S. Fitze, Alberto Jimenez-Valverde, Jorge Ari Noriega, Maria L. Pelaez
Article
Zoology
Enrique Ledesma, Alberto Jimenez-Valverde, Enrique Baquero, Rafael Jordana, Alberto de Castro, Vicente M. Ortuno
Article
Zoology
Miguel Penalver-Alcazar, Alberto Jimenez-Valverde, Pedro Aragon
Summary: Intraspecific variation impacts the performance of species distribution models, with geographically structured phylogenetic lineages showing differences in predicted potential distribution and environmental factors. Model predictive capacity varies depending on the algorithm used, and lineages exhibit low niche overlap, occurring in different environmental niches. Improved predictivity is observed in lineage-level distribution models, with partial spatial agreement between niche overlap and reported secondary contact zones.
Review
Zoology
Alberto Sendra, Ferran Palero, Alberto Jimenez-Valverde, Ana Sofia P. S. Reboleira
Summary: Diplurans are considered an exceptional group of animals adapted to cave environments, playing a crucial role in organic matter decomposition underground and being sensitive to human impacts. Comprehensive research is needed to fill knowledge gaps and aid in the conservation of cave ecosystems.
ZOOLOGICAL JOURNAL OF THE LINNEAN SOCIETY
(2021)
Article
Plant Sciences
Alberto Sendra, Ana Komericki, Josiane Lips, Yunxia Luan, Jesus Selfa, Alberto Jimenez-Valverde
Summary: This study identified two new genera and four new species of Diplura from caves in China and Myanmar, showcasing impressive morphological adaptation to cave ecosystems. The discovery highlights the biogeographical importance of biodiversity in East Asia, with vast karst regions still waiting to be explored and new species of diplurans waiting to be discovered.
EUROPEAN JOURNAL OF TAXONOMY
(2021)
Article
Biodiversity Conservation
Alberto Jimenez-Valverde
Summary: This study found that AUC and Se* are unbiased estimators and achieve the highest precision when prevalence is balanced. Increasing sample size leads to greater stability in the prevalence interval around 0.5. For sample sizes n <= 100, at least ten observations of the rare state should be considered, while a prevalence interval of [0.01, 0.99] is recommended for higher sample sizes.
BIODIVERSITY AND CONSERVATION
(2021)
Review
Biodiversity Conservation
Alberto Sendra, Alberto Jimenez-Valverde, Jesus Selfa, Ana Sofia P. S. Reboleira
Summary: Diplura is a basal hexapod group related to insects, with unique entognathan mouthparts, widespread distribution in terrestrial habitats, and dependence on high humidity and moderate temperatures. They are potentially sensitive to anthropogenic pressures and climate change, making them important targets for ecophysiological studies and conservation efforts.
INSECT CONSERVATION AND DIVERSITY
(2021)
Article
Zoology
Alberto Sendra, Spela Borko, Alberto Jimenez-Valverde, Jesus Selfa, Marko Lukic, Kazimir Miculinic, Tonci Rada, Dragan Antic
Summary: This study describes five new cave-adapted campodeids species, highlighting the importance of the Dinarides karst region as a center of diversification for campodeids and cave animals in general. Four out of five subgenera were present in the region studied, with a monophyletic subgroup colonizing the Dinaric plate during the middle of the Cenozoic.
REVUE SUISSE DE ZOOLOGIE
(2021)
Article
Zoology
J. L. Horreo, A. Jimenez-Valverde, P. S. Fitze
Summary: The research indicates that viviparous clades prefer habitats with less variable temperature and precipitation, while oviparous clades prefer habitats with more variable temperatures. Analysis using reproductive period climates confirms that viviparous lizards exhibit selfish behavior of mothers in relatively safer environments, giving them an adaptive advantage in survival.
FRONTIERS IN ZOOLOGY
(2021)
Article
Ecology
Alberto Jimenez-Valverde
Summary: This paper proposes a methodology to harmonize the distribution of suitability values in species distribution models, and harmonizes the area under the receiver operating characteristic curve (AUC) for comparison between different datasets. The author validates the method through simulations and empirical studies, and expects it to be useful in other research areas dealing with discrimination/classification problems.
METHODS IN ECOLOGY AND EVOLUTION
(2022)
Article
Plant Sciences
Alberto Sendra, Ferran Palero, Alba Sanchez-Garcia, Alberto Jimenez-Valverde, Jesus Selfa, Eter Maghradze, Shalva Barjadze
Summary: The article describes a new dipluran species, Plusiocampa (Plusiocampa) imereti, discovered in caves in the Imereti region of Georgia, which is a new addition to four other known Diplura species in the Black Sea region. This study provides the first CO1 sequences for Plusiocampinae taxa and the first molecular data for cave-dwelling Plusiocampa species in the region.
EUROPEAN JOURNAL OF TAXONOMY
(2021)
Article
Biodiversity Conservation
Marlon E. Cobos, Vijay Barve, Narayani Barve, Alberto Jimenez-Valverde, Claudia Nunez-Penichet
Summary: This article introduces rangemap, an R package that provides tools for exploring species' geographic distributions. The package includes analysis tools and visualization tools that can generate simple summaries and figures of species' ranges. It also allows for the generation of extents of occurrence and areas of occupancy based on IUCN criteria.
BIODIVERSITY INFORMATICS
(2022)
Article
Ecology
Alberto Jimenez-Valverde, Pedro Aragon, Jorge M. Lobo
Summary: Estimating local suitability with species distribution models (SDMs) can indicate the maximum abundance attainable by species, but the abundance-suitability relationship is typically wedge-shaped. The shape of this relationship is directly related to maximum abundance and is influenced by SDM quality and species prevalence.
GLOBAL ECOLOGY AND BIOGEOGRAPHY
(2021)
Article
Biodiversity Conservation
Alberto Jimenez-Valverde, Marta Rodriguez-Rey, Pablo Pena-Aguilera
Summary: This study compared global WorldClim v.2 database (WC) with regional Iberian Climate Atlas (ICA) in the geographical context of the Iberian Peninsula, focusing on differences in climatic variables and their impact on woody plant distribution models. Significant discrepancies were found in precipitation values between the two databases, while temperature values also showed noticeable differences, especially in high elevation areas. The source of climate data influenced estimated suitability values, discrimination capacity, and the importance of variables in the distribution models. Additionally, the rarity of species was associated with increased uncertainty related to the climate data source.
BIODIVERSITY AND CONSERVATION
(2021)
Article
Biodiversity Conservation
Yongcui Lan, Jinliang Wang, Qianwei Liu, Fang Liu, Lanfang Liu, Jie Li, Mengjia Luo
Summary: This study focuses on the five major plateau lake basins in central Yunnan, China, and constructs an ecological security pattern using the source-resistance surface-corridor-pinch point framework. The study simulates land use/cover change in the region and identifies early warning regions where future urban expansion poses a threat to current ecological source areas and corridors.
ECOLOGICAL INDICATORS
(2024)
Article
Biodiversity Conservation
Pingping Huang, Feng Zhao, Bailing Zhou, Kuidong Xu
Summary: This study investigates the distribution of benthic microeukaryotes in the China Seas and finds that they can stride over the ecological barrier of 32 degrees N. The study also highlights the significant influence of depth, temperature, and latitude on communities in the China Seas.
ECOLOGICAL INDICATORS
(2024)
Article
Biodiversity Conservation
Federico Morelli, Yanina Benedetti, Jesse Stanford, Leszek Jerzak, Piotr Tryjanowski, Paolo Perna, Riccardo Santolini
Summary: Species distribution models (SDMs) are numerical tools used for predicting species' spatial distribution. This study found that ecological characteristics, such as habitat specialization, play a role in improving the accuracy of SDMs.
ECOLOGICAL INDICATORS
(2024)
Article
Biodiversity Conservation
Xiaoxuan Wu, Hang Liu, Wei Liu
Summary: Global climate change, urbanization, and economic development have increased the need for sustainable human development, urban ecological governance, and low-carbon energy transformation. This study analyzes the green ecological transition in Chengdu based on panel data from 2010 to 2020, exploring its spatiotemporal evolution and key factors. The results show an overall upward trend in Chengdu's green ecological development and positive spatial autocorrelation in certain districts.
ECOLOGICAL INDICATORS
(2024)
Article
Biodiversity Conservation
Castaldi Simona, Formicola Nicola, Mastrocicco Micol, Morales Rodriguez Carmen, Morelli Raffaella, Prodorutti Daniele, Vannini Andrea, Zanzotti Roberto
Summary: Sustainable agricultural practices are increasingly important for global and national environmental policies and economy. This study compared the sustainability of grape production under integrated and organic management using multiple indicators. The results showed that organic management was more beneficial for most environmental aspects of the agroecosystem compared to integrated management, without affecting grape yield.
ECOLOGICAL INDICATORS
(2024)
Article
Biodiversity Conservation
Gaia Vaglio Laurin, Alexander Cotrina-Sanchez, Luca Belelli-Marchesini, Enrico Tomelleri, Giovanna Battipaglia, Claudia Cocozza, Francesco Niccoli, Jerzy Piotr Kabala, Damiano Gianelle, Loris Vescovo, Luca Da Ros, Riccardo Valentini
Summary: Phenology monitoring is important for understanding forest functioning and climate impacts. This research compares the phenological behavior of European beech forests using Tree-Talker (TT+) and Sentinel 2 satellite data. The study finds differences in the information derived by the two sensor types, particularly in terms of season length, phenology changepoints, and leaf period variability. TT+ with its higher temporal resolution demonstrates precision in capturing the phenological changepoints, especially when satellite image availability is limited.
ECOLOGICAL INDICATORS
(2024)
Article
Biodiversity Conservation
Huanhuan Pan, Ziqiang Du, Zhitao Wu, Hong Zhang, Keming Ma
Summary: The land use and cover changes resulting from coal mining activities and ecological restoration have had a significant impact on ecosystem services in mining areas. This study investigates the relationship between ecosystem services and land use intensity in coal mining areas, emphasizing the importance of understanding this interdependence for balanced human-land system development. The research examines the evolving relationship across different reclamation stages in Shanxi, China, using a coupling coordination degree model. The findings suggest the need for timely and judicious reclamation of coalfields, considering the land's bearing capacity.
ECOLOGICAL INDICATORS
(2024)
Article
Biodiversity Conservation
Jingjuan He, Yijun Shi, Lihua Xu, Zhangwei Lu, Mao Feng
Summary: This study examines the spatial interplay between changes in the blue-green spatial distribution and modifications in land surface temperature grades in Shanghai. The findings reveal that the transformation of the blue-green spatial pattern differs between different sectors of the city, and the impact on the thermal environment varies spatially.
ECOLOGICAL INDICATORS
(2024)
Article
Biodiversity Conservation
Yi Xu, Di Zhang, Junqiang Lin, Qidong Peng, Xiaohui Lei, Tiantian Jin, Jia Wang, Ruifang Yuan
Summary: This study analyzed the response relationship between phytoplankton growth and water environmental parameters in the Middle Route of the South-to-North Water Diversion Project in China using long-term monitoring data and machine learning models. The results revealed the differences between monitoring sites and identified the key parameters that affect phytoplankton growth.
ECOLOGICAL INDICATORS
(2024)