Review
Microbiology
Jonathon L. Baker
Summary: Research on the oral microbiome using omics approaches is crucial for improving human health and quality of life. This review provides a comprehensive perspective on the current state-of-the-art tools available for analyzing and studying the oral microbiome.
FEMS MICROBIOLOGY REVIEWS
(2023)
Review
Oncology
Zijian Zou, Wei Sun, Yu Xu, Wanlin Liu, Jingqin Zhong, Xinyi Lin, Yong Chen
Summary: Sarcomas are rare mesenchymal neoplasms with unique genetic characteristics, and their diagnosis relies heavily on pathological examination. Advanced treatments and multi-omics approaches have shown promise in improving outcomes and understanding sarcomas, but further research is needed to optimize their clinical application.
FRONTIERS IN ONCOLOGY
(2022)
Review
Biotechnology & Applied Microbiology
Alexander Arsov, Kaloyan Petrov, Penka Petrova
Summary: This article discusses the potential of microbial production of butanol as a new fuel and the challenge of butanol toxicity to microbes. Modern omics approaches have made significant progress in addressing the issue of low butanol tolerance, but a strain capable of both synthesis and tolerance at commercializable concentrations has yet to be discovered or produced.
BIOTECHNOLOGY ADVANCES
(2021)
Review
Food Science & Technology
Karolinny Cristiny de Oliveira Vieira, Hevelin Regiane Augusto da Silva, Isabela Poletto Masselli Rocha, Emmanuel Barboza, Lizziane Kretli Winkelstroter Eller
Summary: Outbreaks and deaths related to Foodborne Diseases (FBD) are constantly occurring worldwide, largely due to consumption of contaminated foodstuffs with pathogens. This review discusses the main omic techniques applied in foodborne pathogens and their potential in ensuring food safety. Omics have been shown to integrate variables that contribute to food safety and improve consumer health, costs, and product quality.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Review
Plant Sciences
Federico Scossa, Saleh Alseekh, Alisdair R. Fernie
Summary: Our agricultural systems are facing the urgent challenge of feeding a growing global population, requiring a better understanding of plant genetic and phenotypic diversity. Recent advances in plant genomics, combined with molecular profiling approaches such as genomics, transcriptomics, and metabolomics, offer insights into the complex architecture of agricultural traits and guide crop breeding strategies.
JOURNAL OF PLANT PHYSIOLOGY
(2021)
Review
Cell Biology
Jia-Chen Liu, Shan-Shan Dong, Hui Shen, Dan-Yue Yang, Bin-Bin Chen, Xue-Ying Ma, Yi-Ran Peng, Hong-Mei Xiao, Hong-Wen Deng
Summary: Sarcopenia is a systemic disease characterized by muscle dysfunction, with its genetic architecture and molecular mechanisms still largely unclear. Recent advancements in multi-omics studies offer new insights into the pathogenesis of sarcopenia and may lead to new clinical applications.
AGEING RESEARCH REVIEWS
(2022)
Review
Pharmacology & Pharmacy
Mengyuan Kan, Blanca E. Himes
Summary: Glucocorticoid drugs are widely used in the treatment of diseases, but there is still much to learn about their cell type-specific mechanisms and why patients respond differently. Recent studies have used genomics, transcriptomics, and other omics approaches to address these questions, but there are still knowledge gaps to be filled related to glucocorticoid action mechanisms.
PHARMACOLOGY & THERAPEUTICS
(2021)
Review
Plant Sciences
Yamshi Arif, Priyanka Singh, Andrzej Bajguz, Pravej Alam, Shamsul Hayat
Summary: This review discusses the crucial role of silicon in plant development and stress responses, highlighting its interactions with plant hormones and antioxidants, as well as its application in 'omic approaches. Furthermore, it emphasizes the need for further research on the role of silicon during abiotic stress in plants for a better understanding at a broader level.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2021)
Review
Biotechnology & Applied Microbiology
Ranjna Sirohi, Jaemin Joun, Hong Ii Choi, Vivek Kumar Gaur, Sang Jun Sim
Summary: This article discusses the potential of microalgae as an energy feedstock and the efforts to increase microalgae productivity using various omics techniques, with a particular focus on the application of genome sequencing and metabolic engineering in this field.
MICROBIAL CELL FACTORIES
(2021)
Review
Fisheries
Thao V. Nguyen, Andrea C. Alfaro, Craig Mundy, Jillian Petersen, Norman L. C. Ragg
Summary: The steady increase in global abalone aquaculture production has led to growing interest in applying new technologies, such as omics approaches, for abalone research. Omics techniques like genomics, transcriptomics, proteomics, and metabolomics are revealing key molecules and pathways in biological processes and identifying potential biomarkers. Integration of multiple omics approaches shows great potential in overcoming challenges and limitations to improve abalone production.
Review
Food Science & Technology
Choo Hock Tan
Summary: Venomic research utilizes various techniques to comprehensively understand the diversity and complexity of venom, with applications in treating envenoming, biodiscovery, and conservation. Snake venom proteomics is extensively studied, but the diverse methods and vast amount of information present challenges in data comparison and interpretation.
Review
Biochemistry & Molecular Biology
Theodore Alexandrov, Julio Saez-Rodriguez, Sinem K. Saka
Summary: Spatial omics is a rapidly growing field that integrates imaging and omics to obtain spatially resolved information. It has opened up new opportunities and challenges for method developers and provides a new window into spatial biology.
MOLECULAR SYSTEMS BIOLOGY
(2023)
Review
Biochemistry & Molecular Biology
Qiaolifan Aerqin, Zuo-Teng Wang, Kai-Min Wu, Xiao-Yu He, Qiang Dong, Jin-Tai Yu
Summary: This review summarizes the progress made in the discovery of reliable Alzheimer's disease (AD) biomarkers using genomics, transcriptomics, proteomics, and metabolomics. The importance of these biomarkers in the diagnosis and treatment of AD is discussed.
CELLULAR AND MOLECULAR LIFE SCIENCES
(2022)
Review
Microbiology
Ze Xiang, Jiayuan Li, Di Lu, Xuyong Wei, Xiao Xu
Summary: Viral hepatitis is a significant global public health problem that affects millions of people and has high morbidity and mortality. Multi-omics analysis has been widely used in studying the origin, diagnosis, and treatment targets of viral hepatitis.
FRONTIERS IN MICROBIOLOGY
(2022)
Review
Plant Sciences
Umer Mahmood, Xiaodong Li, Yonghai Fan, Wei Chang, Yue Niu, Jiana Li, Cunmin Qu, Kun Lu
Summary: Crop production is facing challenges from increasing food demand and climate change. Advances in omics techniques and machine learning algorithms can accelerate crop breeding to cope with these challenges. Plant breeding and genetic engineering can develop nutrient sufficient and climate-resilient crops.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Medicine, General & Internal
Shankargouda Patil, Pradeep Kumar Yadalam, Jagadish Hosmani, Zafar Ali Khan, Zeeshan Heera Ahmed, Vidya Gurram Shankar, Kamran Habib Awan
Summary: Oral immune-mediated disorders are a group of oral diseases or conditions that may result from an abnormality in the individual's normal immune response. Some of these disorders are associated with malignancy. This article provides an overview of several oral diseases, such as oral lichen planus, primary Sjogren's syndrome, systemic lupus erythematosus, dermatitis herpetiformis, and linear immunoglobulin A bullous dermatosis, which are caused by irregularities in the immune system and have the potential to undergo malignant transformation, thereby increasing morbidity and mortality rates.
DM DISEASE-A-MONTH
(2023)
Review
Dentistry, Oral Surgery & Medicine
Hosam Ali Baeshen, Tarek El-Bialy, Abdulrahman Alshehri, Wael Awadh, Jacob Thomas, Harnoor Dhillon, Shankargouda Patil
Summary: A systematic review of the literature revealed that clear aligners can have an impact on patients' speech, causing pronunciation errors and speech difficulties. However, these issues were temporary and most patients adapted to the aligners and recovered their normal speech.
EUROPEAN JOURNAL OF ORTHODONTICS
(2023)
Article
Chemistry, Organic
Ismail Celik, Mithun Rudrapal, Pradeep Kumar Yadalam, Sampath Chinnam, Thodur Madapusi Balaji, Saranya Varadarajan, Johra Khan, Shankargouda Patil, Sanjay G. Walode, Dhiraj Panke
Summary: This study investigated the binding affinity and inhibitory activity of resveratrol and its two natural analogues against the Rhizopus oryzae specific RdRp through computer simulations. The results suggest that these compounds could be potential candidates for the treatment of mucormycosis.
POLYCYCLIC AROMATIC COMPOUNDS
(2023)
Article
Dentistry, Oral Surgery & Medicine
Umarevathi Gopalakrishnan, Rajalakshmi Thakshina Murthy, A. Sumathi Felicita, Abdulrahman Alshehri, Wael Awadh, Abdullah Almalki, Thilla Sekar Vinothkumar, Hosam Ali Baeshen, Shilpa Bhandi, Arvind Kathir, Abhinaya Samala, A. Thirumal Raj, Artak Heboyan, Shankargouda Patil
Summary: This study aimed to examine the prevalence of sulfate-reducing bacteria (SRB) in orthodontic patients undergoing fixed appliance treatment. The results showed that the prevalence of SRB was significantly higher in orthodontic patients compared to non-orthodontic participants. This may be attributed to the presence of stainless steel in the oral environment facilitating the colonization of SRB.
INTERNATIONAL DENTAL JOURNAL
(2023)
Article
Dentistry, Oral Surgery & Medicine
Jaideep Mahendra, Little Mahendra, Vivek Sharma, Ahmed Alamoudi, Hammam Ahmed Bahammam, Maryam H. Mugri, Sarah Ahmed Bahammam, Maha A. Bahammam, Bassam Zidane, Rao P. Abirami Nayaki, Janani Muralidharan, Pavithra H. Dave, Thodur Madapusi Balaji, Shilpa Bhandi, Shankargouda Patil
Summary: This study aimed to explore the levels of periodontal red-complex bacteria (RCB) in pregnant women with periodontal disease and its association with preeclampsia. The results showed that preeclamptic women with periodontitis had higher periodontal indices, blood pressure, and urine protein content. Therefore, reducing the periodontal bacterial load in pregnant women through good oral hygiene maintenance can further decrease the risk of adverse pregnancy outcomes, including preeclampsia.
INTERNATIONAL DENTAL JOURNAL
(2023)
Review
Cell Biology
Srimanta Patra, Shankargouda Patil, Daniel J. J. Klionsky, Sujit K. K. Bhutia
Summary: Recent studies have shown that lysosomes, traditionally thought of as static garbage disposals, play a dynamic and multi-functional role in maintaining cellular homeostasis. Lysosomes sense cellular metabolic status and regulate the balance between catabolism and anabolism through signaling pathways, proteins, and transcription factors. Lysosomes also interact with other organelles and their positioning and motility are critical for cellular adaptation. Furthermore, lysosomes can orchestrate different cell death mechanisms to maintain cellular homeostasis, highlighting their central role as a signaling hub.
JOURNAL OF CELLULAR PHYSIOLOGY
(2023)
Article
Environmental Sciences
Priyankar Chakraborthy, Potluri Leela Ravishankar, Anbukumari Vadivelu Saravanan, Khalid J. Alzahrani, Ibrahim F. Halawan, Saleh Alshammeri, Mrim M. Alnfiai, Hosam Ali Baeshen, Sarah Yasser M. Qattan, Ammar Almarghlani, Sunanda Rao Karkala, Anila Neelakandan, Shankargouda Patil
Summary: This study aimed to compare the effectiveness of AmnioGuard and BioMesh in combination with NovaBone putty in intrabony defects. The results showed that at 6 months post-operatively, Group B had a statistically significant change in both clinical and radiographic measures (33% bone gain) compared to Group A (16% bone gain).
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2023)
Article
Medicine, Research & Experimental
Aishwaraya Veerabadran Loganathan, Sangeetha Subramanian, P. S. G. Prakash, Devapriya Appukuttan, Jasmine Crena, Khalid J. Alzahrani, Khalaf Alsharif, Ibrahim Faisal F. Halawani, Fuad M. Alzahrani, Saleh Alshammeri, Maha A. Bahammam, Thodur Madapusi Balaji, Hosam Ali Baeshen, Shankargouda Patil
Summary: This study conducted in India evaluated and compared the clinical outcomes of using connective tissue graft and lyophilized chorion membrane in treating gingival recession in chronic smokers. The results demonstrated the favorable role of lyophilized chorion membrane in root coverage procedures for smokers.
MEDICAL SCIENCE MONITOR
(2023)
Review
Multidisciplinary Sciences
Shankargouda Patil, Shilpa Bhandi, Mohammed Mousa H. Bakri, Dhalia H. Albar, Khalid J. Alzahrani, Mohammad S. Al-Ghamdi, Mrim M. Alnfiai, Marcos Roberto Tovani-Palone
Summary: Patients with prolonged edentulism face challenges in replacing missing teeth. The use of non-resorbable and resorbable membranes in guided bone regeneration showed similar efficacy. However, further research is needed to draw conclusive results due to the low quality of evidence.
Article
Cell Biology
Prakash P. Praharaj, Srimanta Patra, Soumya R. Mishra, Subhadip Mukhopadhyay, Daniel J. Klionsky, Shankargouda Patil, Sujit K. Bhutia
Summary: This study found that cisplatin treatment activated higher mitophagy in oral cancer stem cells by regulating CLU levels. CLU regulated mitochondrial fission by activating AKT kinase, leading to mitochondrial fission. Furthermore, CLU-mediated mitophagy positively regulated oral cancer stem cells by degrading MSX2 and preventing its nuclear translocation, which suppressed SOX2 activity and inhibited cancer stemness and self-renewal ability.
Article
Medicine, General & Internal
Arockia Antony Praveen, Santhosh Venkadassalapathy, Dhayanand John Victor, P. S. G. Prakash, Santo Grace Umesh, Hosam Ali Baeshen, Thodur Madapusi Balaji, Shankargouda Patil, Rodolfo Reda, Luca Testarelli
Summary: The study aimed to compare the efficacy of two hydrodynamic sinus lifting procedures in placing immediate implants in maxillary posterior sites with compromised native bone. The MIAMBE group had lower rates of sinus membrane perforations and nasal bleeding, as well as lower VAS scores, compared to the DIHSFE group. Post-operative sinusitis rates did not differ significantly between the two groups. Therefore, MIAMBE appears to have superior patient outcomes and fewer complications compared to DIHSFE.
PATIENT PREFERENCE AND ADHERENCE
(2023)
Article
Medicine, General & Internal
Geetha Ari, Sathish Rajendran, Jaideep Mahendra, N. Ambalavanan, Shonali Vijayaraj, Little Mahendra, Thodur Madapusi Balaji, Hosam Ali Baeshen, Shankargouda Patil, Rodolfo Reda, Luca Testarelli
Summary: The purpose of this study was to estimate and compare the levels of NT-proBNP in saliva and GCF in systemically healthy subjects with severe chronic periodontitis before and after periodontal flap surgery. The results showed that NT-proBNP levels were higher in the periodontitis group compared to the controls, and they decreased following surgical periodontal therapy. The findings suggest that NT-proBNP could serve as a potential biomarker for periodontitis in saliva and GCF.
INTERNATIONAL JOURNAL OF GENERAL MEDICINE
(2023)
Review
Dentistry, Oral Surgery & Medicine
Shankargouda Patil, Tim Joda, Burke Soffe, Kamran H. Awan, Hytham N. Fageeh, Marcos Roberto Tovani-Palone, Frank W. Licari
Summary: This systematic review evaluated the efficacy of AI models in detecting radiographic periodontal bone loss (PBL) and accuracy in classifying lesions. The results suggest that AI has the potential to aid in the detection of PBL and classification of periodontal diseases, but further research is needed to standardize AI algorithms and validate their clinical usefulness.
JOURNAL OF THE AMERICAN DENTAL ASSOCIATION
(2023)
Article
Medicine, General & Internal
Rajib Dhar, Arikketh Devi, Shankargouda Patil, Marcos Roberto Tovani-Palone
Summary: This article discusses the involvement of exosomes, a subpopulation of extracellular vesicles secreted by cells in normal or pathological conditions, in cancer progression and their potential as a therapeutic tool based on their molecular signature for investigating cancer biomarkers. Recent research also reveals the potential role of exosomes in anticancer drug delivery and their future orientation in theranostics perspectives.
ELECTRONIC JOURNAL OF GENERAL MEDICINE
(2023)
Correction
Dentistry, Oral Surgery & Medicine
Mamata S. Kamat, Rudrayya S. Puranik, A. Bhagavan Das Rai, B. R. Patil, Shankargouda Patil
CLINICAL ORAL INVESTIGATIONS
(2023)
